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Acquisitions and Divestiture (Tables)
12 Months Ended
Dec. 31, 2019
Business Combinations [Abstract]  
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed
The following table summarizes the amounts recognized for assets acquired and liabilities assumed as of the acquisition date:
Estimated Fair Value at February 15, 2019
Acquired IPR&D(1)
$
4,670.0

Finite-lived intangibles(2)
980.0

Deferred income taxes
(1,032.8
)
Other assets and liabilities - net
(26.4
)
Total identifiable net assets
4,590.8

Goodwill(3)
2,326.9

Total consideration transferred - net of cash acquired
$
6,917.7

(1) $4.60 billion of the acquired IPR&D relates to selpercatinib (LOXO-292).
(2) Contract-based intangibles (primarily related to Vitrakvi) which are being amortized to cost of sales on a straight-line basis over their estimated useful lives, were expected to have a weighted average useful life of approximately 12 years from the acquisition date.
(3) The goodwill recognized from this acquisition is attributable primarily to future unidentified projects and products and the assembled workforce for Loxo and is not deductible for tax purposes.
Schedule of Research and Development Assets Acquired Other than Through Business Combination
The following table and narrative summarize our asset acquisitions during 2019, 2018, and 2017.
Counterparty
Compound(s),Therapy, or Asset
Acquisition Month
 
Phase of Development(1)
 
Acquired IPR&D Expense
AC Immune SA
Tau aggregation inhibitor small molecules for the potential treatment of Alzheimer's disease and other neurodegenerative diseases
January 2019 & September 2019(2)
 
Pre-clinical
 
$
127.1

ImmuNext, Inc.
Novel immunometabolism target
March 2019
 
Pre-clinical
 
40.0

Avidity Biosciences, Inc.
Potential new medicines in immunology and other select indications
April 2019
 
Pre-clinical
 
25.0

Centrexion Therapeutics Corporation
CNTX-0290, a novel, small molecule somatostatin receptor type 4 agonist
July 2019
 
Phase I
 
47.5

 
 
 
 
 
 
 
Sigilon Therapeutics
Encapsulated cell therapies for the potential treatment of type 1 diabetes
April 2018
 
Pre-clinical
 
66.9

AurKa Pharma, Inc.
AK-01, an Aurora kinase A inhibitor
June 2018
 
Phase I
 
81.8

ARMO BioSciences, Inc. (ARMO)
Cancer therapy - pegilodecakin
June 2018
 
Phase III
 
1,475.8

Anima Biotech
Translation inhibitors for selected neuroscience targets
July 2018
 
Pre-clinical
 
30.0

SIGA Technologies, Inc.
Priority Review Voucher
October 2018
 
Not applicable
 
80.0

Chugai Pharmaceutical Company
OWL833, an oral non-peptidic GLP-1 receptor agonist
October 2018
 
Pre-clinical
 
50.0

NextCure, Inc.
Immuno-oncology cancer therapies
November 2018
 
Pre-clinical(3)
 
28.1

Dicerna Pharmaceuticals, Inc.
Cardio-metabolic disease, neurodegeneration, and pain
December 2018
 
Pre-clinical
 
148.7

Hydra Biosciences
TRPA1 antagonists program for the potential treatment of chronic pain syndromes
December 2018
 
Pre-clinical
 
22.6

 
 
 
 
 
 
 
CoLucid Pharmaceuticals, Inc. (CoLucid)
Oral therapy for the acute treatment of migraine - lasmiditan
March 2017
 
Phase III
 
857.6

KeyBioscience AG
Multiple molecules for treatment of metabolic disorders
July 2017
 
Phase II
 
55.0

Nektar Therapeutics
Immunological therapy - NKTR-358
August 2017
 
Phase I
 
150.0

CureVac AG
Cancer vaccines
November 2017
 
Pre-clinical
 
50.0

(1) The phase of development presented is as of the date of the arrangement and represents the phase of development of the most advanced asset acquired, where applicable.
(2) We recognized acquired IPR&D expenses of $96.9 million in January 2019 upon entering into a license agreement and $30.2 million in September 2019 upon entering into an amendment to the license agreement.
(3) This research and development collaboration agreement has been terminated, to be effective March 2020.