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Income Taxes (Reconciliation of Income Taxes) (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Income Tax Disclosure [Abstract]                      
Income tax at the U.S. federal statutory tax rate                 $ 797.1 $ 769.1 $ 1,180.9
Add (deduct):                      
International operations, including Puerto Rico                 (629.7) (428.9) (313.7)
General business credits                 (87.4) (66.8) (58.3)
Non-deductible acquired IPR&D                 309.9 300.1 0.0
2017 Tax Act                   1,914.0 0.0
2017 Tax Act                 175.3    
Other                 (1.5) (86.0) (172.5)
Income taxes $ (186.2) $ 261.5 $ 264.7 $ 223.6 $ 1,941.0 $ 36.0 $ 252.5 $ 172.0 $ 563.7 $ 2,401.5 $ 636.4