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Summary of Significant Accounting Policies (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Average Remaining Maturity of Foreign Currency Derivatives                 12 months    
Depreciation                 $ 716.2 $ 717.6 $ 759.1
Operating Leases, Rent Expense                 221.0 225.7 227.3
Collaboration and other revenue                 833.7 808.1 788.4
Revenue $ 5,760.5 $ 5,191.7 $ 5,404.8 $ 4,865.1 $ 5,375.6 $ 4,959.7 $ 4,978.7 $ 4,644.7 $ 21,222.1 $ 19,958.7 $ 19,615.6
Minimum [Member]                      
Finite-Lived Intangible Assets, Useful Life                 3 years    
Minimum [Member] | Building [Member]                      
Property, Plant and Equipment, Useful Life                 12 years    
Minimum [Member] | Equipment [Member]                      
Property, Plant and Equipment, Useful Life                 3 years    
Maximum [Member]                      
Finite-Lived Intangible Assets, Useful Life                 20 years    
Maximum [Member] | Building [Member]                      
Property, Plant and Equipment, Useful Life                 50 years    
Maximum [Member] | Equipment [Member]                      
Property, Plant and Equipment, Useful Life                 25 years