Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Millions	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Revenue	$ 21,222.1	$ 19,958.7	$ 19,615.6
Costs, expenses, and other:
Cost of sales	5,654.9	5,037.2	4,932.5
Research and development	5,243.9	4,796.4	4,733.6
Marketing, selling, and administrative	6,452.0	6,533.0	6,620.8
Acquired in-process research and development	30.0	535.0	200.2
Asset impairment, restructuring, and other special charges	382.5	367.7	468.7
Other-net, (income) expense	84.8	(100.6)	(340.5)
Cost of sales, operating expenses, and other-net	17,848.1	17,168.7	16,615.3
Income before income taxes	3,374.0	2,790.0	3,000.3
Income taxes	636.4	381.6	609.8
Net income	$ 2,737.6	$ 2,408.4	$ 2,390.5
Earnings per share:
Basic	$ 2.59	$ 2.27	$ 2.23
Diluted	$ 2.58	$ 2.26	$ 2.23
Shares used in calculation of earnings per share:
Basic	1,058,324	1,061,913	1,069,932
Diluted	1,061,825	1,065,720	1,074,286