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Collaborations (Details)
12 Months Ended 1 Months Ended 12 Months Ended 3 Months Ended 1 Months Ended 1 Months Ended 12 Months Ended 3 Months Ended 12 Months Ended 1 Months Ended 3 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 3 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 11 Months Ended 1 Months Ended
Dec. 31, 2012
USD ($)
Dec. 31, 2011
USD ($)
Dec. 31, 2010
USD ($)
Dec. 31, 2012
Erbitux [Member]
USD ($)
Dec. 31, 2011
Erbitux [Member]
USD ($)
Dec. 31, 2010
Erbitux [Member]
USD ($)
Dec. 31, 2012
Effient [Member]
USD ($)
Dec. 31, 2011
Effient [Member]
USD ($)
Dec. 31, 2010
Effient [Member]
USD ($)
Aug. 31, 2012
Amylin [Member]
USD ($)
Nov. 30, 2011
Amylin [Member]
USD ($)
Dec. 31, 2011
Amylin [Member]
USD ($)
Dec. 31, 2010
Amylin [Member]
USD ($)
Dec. 31, 2012
Exenatide [Member]
USD ($)
Dec. 31, 2011
Exenatide [Member]
USD ($)
Dec. 31, 2010
Exenatide [Member]
USD ($)
Mar. 31, 2011
Boerhringer Ingelheim (BI) [Member]
USD ($)
Nov. 30, 2011
Sales NEW [Member]
Amylin [Member]
Aug. 31, 2012
Revenue Share [Member]
Amylin [Member]
USD ($)
Dec. 31, 2012
Revenue Share [Member]
Exenatide Once Weekly [Member]
USD ($)
Nov. 30, 2011
Secured Note [Member]
Amylin [Member]
USD ($)
Dec. 31, 2012
Secured Note [Member]
Amylin [Member]
Dec. 31, 2012
Profit and Development and Marketing Share [Member]
Effient [Member]
Mar. 31, 2010
Prepaid Selling and Marketing Expense [Member]
Duloxetine BI [Member]
USD ($)
Dec. 31, 2012
Royalty Payments Received [Member]
Solanezumab [Member]
USD ($)
Dec. 31, 2009
Research and Development Exp [Member]
Baricitinib [Member]
Nov. 30, 2011
Milestone Payments [Member]
Amylin [Member]
USD ($)
Sep. 30, 2011
Milestone Payments [Member]
TPG-Axon [Member]
USD ($)
Dec. 31, 2012
Milestone Payments [Member]
BI compounds [Member]
EUR (€)
Dec. 31, 2011
Milestone Payments [Member]
BI compounds [Member]
USD ($)
Dec. 31, 2012
Milestone Payments [Member]
LLY compounds [Member]
USD ($)
Dec. 31, 2012
Milestone Payments [Member]
LLY optional compound [Member]
USD ($)
Dec. 31, 2009
Milestone Payments, Development and Regulatory [Member]
Baricitinib [Member]
USD ($)
Dec. 31, 2012
Milestone Payments, Development and Regulatory [Member]
Baricitinib [Member]
USD ($)
Dec. 31, 2010
Milestone Payments, Development and Regulatory [Member]
Baricitinib [Member]
USD ($)
Dec. 31, 2009
Milestone Payments, Sales-based [Member]
Baricitinib [Member]
USD ($)
Jun. 30, 2011
Loan Commitment [Member]
Exenatide Once Weekly [Member]
USD ($)
Dec. 31, 2009
Royalty [Member]
Baricitinib [Member]
Dec. 31, 2012
Funding Commitment [Member]
Necitumumab [Member]
Dec. 31, 2012
United States [Member]
USD ($)
Dec. 31, 2011
United States [Member]
USD ($)
Dec. 31, 2010
United States [Member]
USD ($)
Nov. 30, 2011
United States [Member]
Revenue Share [Member]
Amylin [Member]
Nov. 30, 2011
United States [Member]
Gross Margin Share [Member]
Exenatide [Member]
Nov. 30, 2011
United States [Member]
Research and Development and Marketing and Selling Expense [Member]
Exenatide [Member]
Nov. 30, 2011
Outside the United States [Member]
Sales NEW [Member]
Exenatide [Member]
Nov. 30, 2011
Outside the United States [Member]
Revenue Share [Member]
Amylin [Member]
Sales Revenue, Goods, Net $ 21,970,400,000 $ 23,604,800,000 $ 22,442,200,000 $ 76,400,000 $ 87,600,000 $ 71,900,000 $ 457,200,000 $ 302,500,000 $ 115,000,000         $ 207,800,000 $ 179,600,000 $ 168,100,000                                                              
Collaboration and other revenue 633,000,000 681,700,000 633,800,000 320,600,000 321,600,000 314,200,000               70,100,000 243,100,000 262,500,000                                                              
Revenue 22,603,400,000 24,286,500,000 23,076,000,000 397,000,000 409,200,000 386,100,000               277,900,000 422,700,000 430,600,000                                               12,313,100,000 12,977,200,000 12,865,600,000          
Other Nonoperating Income (Expense) (41,000,000) (72,900,000) 128,600,000                 0 0 787,800,000                                                                  
Research and Development Expense 5,278,100,000 5,020,800,000 4,884,200,000                                                                                        
Proceeds from prepayment of revenue-sharing obligation 1,212,100,000 0 0             1,210,000,000                                                                          
Deferred Revenue, Current                                       490,000,000                                                      
Collaborative Arrangement, Income Statement Classification and Amounts 261,500,000 219,200,000 174,500,000                                                                                        
Collaborative Arrangement, Rights and Obligations                     250,000,000               1,260,000,000         400,000,000 8   150,000,000 70,000,000 300,000,000 478,700,000 300,000,000 525,000,000 515,000,000 50,000,000 49,000,000 150,000,000                      
Collaborative Arrangement, Rights and Obligations Percent                                   15.00%         50.00%     30.00%                       20.00%         65.00% 50.00% 50.00% 100.00% 35.00%
Proceeds from Sales of Business, Affiliate and Productive Assets                                         1,200,000,000                                                    
Debt Instrument, Interest Rate, Stated Percentage                                           9.50%                                                  
Collaborative Arrangement, Rights and Obligations, Term of Arrangement                                                                             18 months                
Acquired in-process research and development 0 388,000,000 50,000,000                           388,000,000                                                            
Payments to Fund Long-term Loans to Related Parties                                                                         $ 165,000,000