-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 J0H33CsSrCW3DIaO+NmTlM/2P620PBmOsDaXL5lyTJNPhfUcZ6qIovlHCk+CpgXC
 t2XVeiklp/P1o9j3cImX3A==

<SEC-DOCUMENT>0001011240-04-000131.txt : 20040901
<SEC-HEADER>0001011240-04-000131.hdr.sgml : 20040901
<ACCEPTANCE-DATETIME>20040901145004
ACCESSION NUMBER:		0001011240-04-000131
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20040831
FILED AS OF DATE:		20040901
DATE AS OF CHANGE:		20040901

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ISAKSON JOHN P
		CENTRAL INDEX KEY:			0001197402

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-09601
		FILM NUMBER:		041010834

	BUSINESS ADDRESS:	
		STREET 1:		2503 SOUTH HANLEY ROAD
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			53144
		BUSINESS PHONE:		3146456600

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			KV PHARMACEUTICAL CO /DE/
		CENTRAL INDEX KEY:			0000057055
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				430618919
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0331

	BUSINESS ADDRESS:	
		STREET 1:		2503 S HANLEY RD
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63144
		BUSINESS PHONE:		3146456600

	MAIL ADDRESS:	
		STREET 1:		2503 S HANLEY RD
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63144
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>kvf4isaks083104_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2004-08-31</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000057055</issuerCik>
        <issuerName>KV PHARMACEUTICAL CO /DE/</issuerName>
        <issuerTradingSymbol>KVA, KVB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001197402</rptOwnerCik>
            <rptOwnerName>ISAKSON JOHN P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>2503 SOUTH HANLEY ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ST LOUIS</rptOwnerCity>
            <rptOwnerState>MO</rptOwnerState>
            <rptOwnerZipCode>63144</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>10.212</value>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2004-08-31</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2500</value>
                    <footnoteId id="F2"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2007-10-21</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Class B Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>5000</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">20% immediately exercisable; additional 20% exercisable on each succeeding anniversary date of grant, pursuant to K-V
Pharmaceutical Company 2001 Incentive Stock Option Plan.</footnote>
        <footnote id="F2">This option was previously reported as covering 5,000 shares at an exercise price of $15.31 per share but was adjusted to
reflect a 3-for-2 stock split on September 8, 2003.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ John P. Isakson</signatureName>
        <signatureDate>2004-09-01</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----