NATIXIS FUNDS TRUST II

May 4, 2023

VIA EDGAR

U.S. Securities and Exchange Commission

100 F Street, NE

Washington, DC 20549

Re: Natixis Funds Trust II

(File Nos.: 002-11101 and 811-00242)

Dear Sir or Madam:

Pursuant to Rule 497(j) of the Securities Act of 1933, as amended, I hereby certify that the Prospectuses and Statements of Additional Information, each dated May 1, 2023, for the AlphaSimplex Global Alternatives Fund, AlphaSimplex Managed Futures Strategy Fund, Loomis Sayles Strategic Alpha Fund, Natixis Oakmark Fund and Vaughan Nelson Mid Cap Fund, each a series of Natixis Funds Trust II, do not differ from those contained in Post-Effective Amendment No. 238 that was filed electronically on April 28, 2023.

Please direct any questions or comments on the enclosed materials to me at (617) 449-2818.

Very truly yours,

/s/ John DelPrete

John DelPrete

Assistant Secretary