[Wyeth letterhead]

September 12, 2007

Mr. Tim Buchmiller, Esq.

Senior Attorney

Division of Corporation Finance

Mail Stop 6010

United States Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Re: Wyeth

Definitive Proxy Statement

Filed March 16, 2007

File No. 1-1225

Dear Mr. Buchmiller:

Further to our telephone conversation of September 7, 2007, Wyeth (the “Company”) acknowledges receipt of the comments of the staff (the “Staff”) of the Division of Corporation Finance of the Securities and Exchange Commission set forth in a letter from the Staff dated August 21, 2007 (the “Comment Letter”) pertaining to the Company’s 2007 Definitive Proxy Statement filed on March 16, 2007. As discussed, the Company is in the process of evaluating and preparing its responses to the Staff’s comments and intends to review the Comment Letter with the Compensation and Benefits Committee of the Company’s Board of Directors at its next meeting. This letter confirms the Company’s intention to submit its formal written response to the Staff’s comments during the week of October 15^th.

We look forward to working with you to address the Staff’s comments.

Very truly yours,
Wyeth
By:	/s/ Bryan A. Supran
	Bryan A. Supran
	Assistant General Counsel - Corporate
cc:	Mr. Robert Essner
	Chairman and Chief Executive Officer
	Mr. Gregory Norden
	Senior Vice President and Chief Financial Officer
	Mr. Lawrence V. Stein
	Senior Vice President and General Counsel