UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 24F-2

                        Annual Notice of Securities Sold
                             Pursuant to Rule 24f-2

Read instructions at end of Form before preparing Form.

1.     Name and address of issuer:
          RiverSource Large Cap Series, Inc.
          200 Ameriprise Financial
          Minneapolis, MN 55474

2.     The name of each series or class of securities for
       which this Form is filed (if the Form is being filed
       for all series and classes of securities of the issuer,
       check the box but do not list series of classes): [ ]
          RiverSource Growth Fund
          RiverSource Large Cap Equity Fund
          RiverSource Large Cap Value Fund

3.     Investment Company Act File Number: 811-2111

       Securities Act File Number: 2-38355

4(a).  Last day of fiscal year for which this Form is filed:
       September 30, 2009

4(b).  Check box if this Form is being file late (i.e., more
       than 90 calendar days after the end of the issuer's
       fiscal year).
       (See Instruction A.2)
          [ ]
          Note: If the Form is being filed late, interest must
          be paid on the registration fee due.

4(c).  Check box if this is the last time the issuer will be
       filing this Form: [ ]

5.     Calculation of registration fee:

       (i)  Aggregate sale price of securities sold during the
            fiscal year pursuant to section 24(f):               $   167,112,432



       (ii) Aggregate price of securities redeemed or
            repurchased during the fiscal year:                  $ 3,943,658,267

       (iii) Aggregate price of securities redeemed or
            repurchased during any prior fiscal year ending no
            earlier than October 11, 1995 that were not
            previously used to reduce registration fees
            payable to the Commission:                           $ 5,952,673,401

       (iv) Total available redemption credits [add Items
            5(ii) and 5(iii)]:                                   $ 9,896,331,668

       (v)  Net sales - if Item 5(i) is greater than Item
            5(iv) [subtract Item 5(iv) from Item 5(i)]:          $          0.00

       (vi) Redemption credits available for use in future
            years if item 5(i) is less than Item5(iv)
            [subtract Item 5(iv) from Item 5(i)]:              - $ 9,729,219,236

       (vii) Multiplier for determining registration fee (see
            Instruction C.9):                                          0.0000558

       (viii) Registration fee due [multiply Item 5(v) by Item
            5(vii)] (enter "0" if no fee is due):                $          0.00

6.     Prepaid Shares

       If the response to Item 5(i) was determined by
       deducting an amount of securities that were registered
       under the Securities Act of 1933 pursuant to rule 24e-2
       as in effect before October 11, 1997, then report the
       amount of securites (number of shares or other units)
       deducted here:__. If there is a number of shares or
       other units that were registered pursuant to the rule
       24e-2 remaining unsold at the end of the fiscal year
       for which this form is filed that are available for use
       by the issuer in future fiscal years, then state that
       number here: __.

7.     Interest Due - if this Form is being filed more than 90
       days after the end of the issuer's fiscal year (see
       Instruction D):                                           $          0.00

8.     Total of the amount of the registration fee due plus
       any interest due [line 5(viii) plus line 7]:              $          0.00

9.     Date the registration fee and any interest payment was
       sent to the Commission's lockbox depository:

       Method of Delivery:

          [ ] Wire Transfer
          [ ] Mail or other means






                                   SIGNATURES

This report has been signed below by the following persons on behalf of the
issuer and in the capacities and on the dates indicated.


By (Signature and Title)*               /s/ Jeffrey P. Fox
                                        ----------------------------------------
                                        Jeffrey P. Fox
                                        Treasurer and Principal Financial
                                        Officer

Date December 10, 2009

*    Please print the name and the title of the signing officer below the
     signature.