EXHIBIT 21

HUMANA INC.

SUBSIDIARY LIST

ALABAMA

Mid-South Home Health Agency, LLC

ARIZONA

Premier Home Health Agency, LLC

ARKANSAS

Humana Regional Health Plan, Inc.

CALIFORNIA

Asian American Home Care, Inc.

Humana EAP and Work-Life Services of California, Inc.

Humana Health Plan of California, Inc.

Professional Healthcare at Home, LLC

COLORADO

Alpine Home Health Care, LLC

DELAWARE

Access Home Health of Florida, LLC

Amazing Home Health Holdings, LLC

American Homecare Management Corp.

CDO 1, LLC

CDO 2, LLC

CenterWell Care Solutions, Inc.

CenterWell Certified Healthcare Corp.

CenterWell Health Services (Certified), Inc.

CenterWell Health Services (USA) LLC

CenterWell Health Services Holding Corp.

CenterWell Health Services, Inc.

CenterWell Pharmacy, Inc.

CompBenefits Corporation

CompBenefits Direct, Inc.

Conviva Care Solutions, LLC

Conviva Care Solutions II, LLC

Conviva Group Holdings, LLC

Conviva Health Management, LLC

Conviva Health MSO of Texas, Inc.

Conviva Medical Center Management, LLC

Eagle NY Rx, LLC

Eagle Rx Holdco, Inc.

Eagle Rx, Inc.

Echo Primary Care Holdings, LLC

Edge Health MSO, Inc.

Emphesys, Inc.

Enclara Pharmacia, Inc.

FPG Acquisition Corp.

FPG Acquisition Holdings Corp.

FPG Holding Company, LLC

Go365, LLC

Harden Healthcare Holdings, LLC

Harden Home Health, LLC

Health Value Management, Inc.

Healthfield Operating Group, LLC

Healthfield, LLC

HHS Healthcare Corp.

Hospice Pharmacy Solutions, LLC

HP Solutions Holdings, LLC

HUM Provider Holdings, LLC

Humana at Home, Inc.

Humana Digital Health and Analytics Platform Services, Inc.

Humana Direct Contracting Entity, Inc.

Humana Government Business, Inc.

Humana Inc.

Humana Innovation Enterprises, Inc.

Humana WellWorks LLC

HumanaDental, Inc.

Integracare Holdings, Inc.

Integracare Intermediate Holdings, Inc.

KAH Development 10, L.L.C.

KAH Development 12, L.L.C.

KAH Development 14, L.L.C.

KAH Development 4, L.L.C.

Kentucky Homecare Holdings, Inc.

Kentucky Homecare Parent Inc.

Kindred Hospice Missouri, LLC

Kindred Hospice Services, L.L.C.

KND Development 50, L.L.C.

Mid-South Home Health, LLC

North Region Providers, LLC

One Home Medical Equipment NC, LLC

One Home Medical Equipment VA, LLC

One Infusion Pharmacy NC, LLC

One Infusion Pharmacy TX, LLC

One Infusion Pharmacy VA, LLC

PBM Holding Company

PBM Plus Mail Service Pharmacy, LLC

PF Development 10, L.L.C.

PF Development 15, L.L.C.

PF Development 16, L.L.C.

PF Development 21, L.L.C.

PF Development 5, L.L.C.

PF Development 7, L.L.C.

PF Development 9, L.L.C.

Pharaoh JV, LLC

PHH Acquisition Corp.

PHHC Acquisition Corp.

Primary Care Holdings II, LLC

Prime West JV Holdings, LLC

Professional Healthcare, LLC

Regency Home Office, LLC

SHC Holding, Inc.

Transcend Population Health Management II, LLC

Voyager Home Health, Inc.

Voyager Hospicecare, Inc.

DOMINICAN REPUBLIC

Trueshore S.R. I.

FLORIDA

Accredited Home Health of Broward, Inc.

Advanced Oncology Services, Inc.

Amazing Home Health Care, Inc.

Amicus Medical Center LLC

Amicus Medical Group, Inc.

Amicus Medical Services Organization, LLC

Care Hope Holdings, Inc.

Care Hope Home Health Agency, Inc.

Care Partners Home Care, LLC

CarePlus Health Plans, Inc.

CenterWell Accountable Care, LLC

CenterWell Senior Primary Care (FL), Inc.

CompBenefits Company

Complex Clinical Management, Inc.

Conviva Physician Group, LLC

Conviva Specialty, LLC

Elite Health Medical Centers, LLC

Elite Health Primary Care, LLC

Enhanz DCE, LLC

FPG Senior Services, LLC

Homecare Holdings, Inc.

HUM-e-FL, Inc.

Humana At Home 1, Inc.

Humana Dental Company

Humana Health Insurance Company of Florida, Inc.

Humana Medical Plan, Inc.

Med. Tech. Services of South Florida, Inc.

Med-Tech Services of Dade, Inc.

Med-Tech Services of Palm Beach, Inc.

METCARE of Florida, Inc.

Metropolitan Health Networks, Inc.

Naples Health Care Specialists, LLC

Nursing Solutions, LLC

On the Way Home Care, Inc.

One Home Health Holdings, LLC

One Home Medical Equipment, LLC

One Homecare Solutions, LLC

One Homecare Systems, LLC

One Infusion Pharmacy, LLC

One Nursing Care, LLC

One TPA Systems, Inc.

SeniorBridge Family Companies (FL), Inc.

SeniorBridge-Florida, LLC

Senior Home Care, Inc.

South Florida Cardiology Associates, LLC

Trueshore BPO, LLC

GEORGIA

Capital Care Resources of South Carolina, LLC

Capital Care Resources, LLC

Capital Health Management Group, LLC

Chattahoochee Valley Home Care Services, LLC

Chattahoochee Valley Home Health, LLC

CHMG Acquisition LLC

CHMG of Atlanta, LLC

CHMG of Griffin, LLC

Healthfield Home Health, LLC

Healthfield of Southwest Georgia, LLC

Healthfield of Statesboro, LLC

Healthfield of Tennessee, LLC

Humana Employers Health Plan of Georgia, Inc.

Kindred at Home Foundation, Inc.

Mid-South Home Health of Gadsden, LLC

Total Care Home Health of Louisburg, LLC

Total Care Home Health of North Carolina, LLC

Total Care Home Health of South Carolina, LLC

ILLINOIS

CompBenefits Dental, Inc.

Dental Care Plus Management, Corp.

Humana Benefit Plan of Illinois, Inc.

Humana Healthcare Research, Inc.

INDIANA

SeniorBridge Family Companies (IN), Inc.

IOWA

Hawkeye Health Services, Inc.

KENTUCKY

516-526 West Main Street Condominium Council of Co-Owners, Inc.

CHA HMO, Inc.

Humana Active Outlook, Inc.

Humana Health Plan, Inc.

Humana Insurance Company of Kentucky

Humana MarketPOINT, Inc.

Humana Pharmacy Solutions, Inc.

Humana Real Estate Company

Humco, Inc.

The Dental Concern, Inc.

LOUISIANA

Humana Health Benefit Plan of Louisiana, Inc.

Synergy Home Care-Acadiana Region, Inc.

Synergy Home Care-Capitol Region, Inc.

Synergy Home Care-Central Region, Inc.

Synergy Home Care-Northeastern Region, Inc.

Synergy Home Care-Northshore Region, Inc.

Synergy Home Care-Northwestern Region, Inc.

Synergy Home Care-Southeastern Region, Inc.

Synergy, Inc.

MICHIGAN

Humana Medical Plan of Michigan, Inc.

Prime Accountable Care West, LLC

Prime West Management, LLC

MISSISSIPPI

Gilbert's Home Health Agency, Inc.

Home Health Care Affiliates of Central Mississippi, L.L.C.

Home Health Care Affiliates of Mississippi, Inc.

Home Health Care Affiliates, Inc.

Van Winkle Home Health Care, Inc.

MISSOURI

Missouri Home Care of Rolla, Inc.

The American Heartland Hospice Corp.

NEVADA

Nevada Independent Physicians, LLC

Southern Nevada Home Health Care, Inc.

NEW YORK

Alexander Infusion, LLC

CenterWell Services of New York, Inc.

Harris, Rothenberg International Inc.

Humana Health Company of New York, Inc.

Humana Insurance Company of New York

New York Healthcare Services, Inc.

SeniorBridge Family Companies (NY), Inc.

QC-Medi New York, Inc.

Quality Care - USA, Inc.

OHIO

Innovative Financial Group Holdings, LLC

Innovative Financial Partners, LLC

Medicare Planning of America LLC

Rees Financial

The Lead Store LLC

Versa Management LLC

OHIO

Humana Health Plan of Ohio, Inc.

Hummingbird Coaching Systems LLC

PENNSYLVANIA

Humana Medical Plan of Pennsylvania, Inc.

PUERTO RICO

Humana Health Plans of Puerto Rico, Inc.

Humana Insurance of Puerto Rico, Inc.

Humana Management Services of Puerto Rico, Inc.

Humana MarketPOINT of Puerto Rico, Inc.

SOUTH CAROLINA

Humana Benefit Plan of South Carolina, Inc.

TENNESSEE

Cariten Health Plan Inc.

PHP Companies, Inc.

Preferred Health Partnership, Inc.

TEXAS

Aberdeen Holdings, Inc.

Able Home Healthcare, Inc.

BWB Sunbelt Home Health Services, LLC

California Hospice, LLC

CompBenefits Insurance Company

Corpus Christi Home Care, Inc.

DentiCare, Inc.

Emphesys Insurance Company

Focus Care Health Resources, Inc.

GBA Holding, Inc.

GBA West, LLC

Georgia Hospice, LLC

Harden Clinical Services, LLC

Harden HC Texas Holdco, LLC

Harden Healthcare, LLC

Harden Hospice, LLC

Home Health of Rural Texas, Inc.

Horizon Health Care Services, Inc.

Humana At Home (Dallas), Inc.

Humana At Home (Houston), Inc.

Humana At Home (San Antonio), Inc.

Humana At Home (TLC), Inc.

Humana Benefit Plan of Texas, Inc.

Humana Health Plan of Texas, Inc.

Integracare Home Health Services, Inc.

Integracare of Albany, LLC

Integracare of Athens-Home Health, LLC

Integracare of Olney Home Health, LLC

Integracare of Texas, LLC

Integracare of West Texas-Home Health, LLC

Integracare of Wichita Falls, LLC

Lighthouse Hospice - Metroplex, LLC

Lighthouse Hospice Management, LLC

Lighthouse Hospice-San Antonio, LLC

One Home Health Holdings CCTX, LLC

One Home Medical Equipment TX, LLC

Outreach Health Services of North Texas, LLC

ROHC, L.L.C.

Texas Dental Plans, Inc.

Vernon Home Health Care Agency, LLC

Voyager Acquisition, L.P.

UTAH

Home Health Services, Inc.

Humana Medical Plan of Utah, Inc.

VERMONT

Managed Care Indemnity, Inc.

WASHINGTON

Arcadian Health Plan, Inc.

WEST VIRGINIA

First Home Health, Inc.

Nursing Care-Home Health Agency, Inc.

WISCONSIN

CareNetwork, Inc.

GuidantRx, Inc.

Humana Insurance Company

Humana Wisconsin Health Organization Insurance Corporation

HumanaDental Insurance Company

Independent Care Health Plan