-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 TjQv4WytZihz/OxdyG+lhh8rOpCN5dnnQFUqcI++SCEhsN2gWuP+bvm+ykb/ECdZ
 imQv5ujaG1xhhRxC2131SA==

<SEC-DOCUMENT>0001181431-05-002882.txt : 20050113
<SEC-HEADER>0001181431-05-002882.hdr.sgml : 20050113
<ACCEPTANCE-DATETIME>20050113170122
ACCESSION NUMBER:		0001181431-05-002882
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050113
FILED AS OF DATE:		20050113
DATE AS OF CHANGE:		20050113

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Bunt Antonius MG
		CENTRAL INDEX KEY:			0001314329

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-10824
		FILM NUMBER:		05528676

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		781-398-2300

	MAIL ADDRESS:	
		STREET 1:		1000 WINTER STREET
		STREET 2:		SUITE 2200
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OSCIENT PHARMACEUTICALS CORP
		CENTRAL INDEX KEY:			0000356830
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				042297484
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1OO BEAVER ST
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02453
		BUSINESS PHONE:		7813982300

	MAIL ADDRESS:	
		STREET 1:		100 BEAVER STREET
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02453

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GENOME THERAPEUTICS CORP
		DATE OF NAME CHANGE:	19941215

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	COLLABORATIVE RESEARCH INC
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>rrd64731.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2005-01-13</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000356830</issuerCik>
        <issuerName>OSCIENT PHARMACEUTICALS CORP</issuerName>
        <issuerTradingSymbol>OSCI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001314329</rptOwnerCik>
            <rptOwnerName>Bunt Antonius MG</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1000 WINTER ST.</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 2200</rptOwnerStreet2>
            <rptOwnerCity>WALTHAM</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02451</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>SVP Clinical Dev.&amp; Med. Affair</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <ownerSignature>
        <signatureName>Robert E. Farrell Jr Corp Controller/Treasurer  Power of Attorney</signatureName>
        <signatureDate>2005-01-13</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----