UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 24F-2
Annual Notice of Securities Sold
Pursuant to Rule 24f-2

Read instructions at end of Form before preparing Form.

1.    Name and address of issuer:
        RiverSource Variable Portfolio Investment Series, Inc.
        200 Ameriprise Financial
        Minneapolis, MN 55474


2.    The name of each series or class of securities for which this
      Form is filed (if the Form is being filed for all series and classes
      of securities of the issuer, check the box but do not list series
      of classes):  [ ]

        RiverSource Variable Portfolio Emerging Markets Fund
        RiverSource Variable Portfolio Growth Fund
        RiverSource Variable Portfolio International Opportunity Fund
        RiverSource Variable Portfolio Large Cap Equity Fund
        RiverSource Variable Portfolio Large Cap Value Fund
        RiverSource Variable Portfolio Mid Cap Growth Fund
        RiverSource Variable Portfolio Mid Cap Value Fund
        RiverSource Variable Portfolio S&P 500 Index Fund
        RiverSource Variable Portfolio Small Cap Advantage Fund

3.    Investment Company Act File Number:
        811-3218

      Securities Act File Number:
        2-73115

4(a). Last day of fiscal year for which this Form is filed:
        December 31, 2006

4(b). Check box if this Form is being file late (i.e., more than 90
      calendar days after the end of the issuer's fiscal year).
      (See Instruction A.2)
        [ ]
        Note: If the Form is being filed late, interest must be paid on the
        registration fee due.

4(c). Check box if this is the last time the issuer will be filing
      this Form:
        [ ]

5.    Calculation of registration fee:

    (i)   Aggregate sale price of securities sold during the fiscal year
          pursuant to section 24(f):
                                                                    $0.00

    (ii)  Aggregate price of securities redeemed or repurchased
          during the fiscal year:
                                                                    $0.00

    (iii) Aggregate price of securities redeemed or repurchased during
          any prior fiscal year ending no earlier than October 11, 1995 that
          were not previously used to reduce registration fees payable to
          the Commission:
                                                                    $0.00

    (iv)  Total available redemption credits
          [add Items 5(ii) and 5(iii)]:
                                                                    $0.00

    (v)   Net sales - if Item 5(i) is greater than Item 5(iv)
          [subtract Item 5(iv) from Item 5(i)]:
                                                                    $0.00

    (vi)  Redemption credits available for use in future years
          if item 5(i) is less than Item5(iv) [subtract Item 5(iv)
          from Item 5(i)]:
                                                                  - $0.00

    (vii) Multiplier for determining registration fee
          (see Instruction C.9):
                                                                 0.0000307

    (viii)Registration fee due [multiply Item 5(v) by Item 5(vii)]
          (enter "0" if no fee is due):
                                                                    $0.00

6.    Prepaid Shares

        If the response to Item 5(i) was determined by deducting an amount
        of securities that were registered under the Securities Act of 1933
        pursuant to rule 24e-2 as in effect before October 11, 1997, then
        report the amount of securites (number of shares or other units)
        deducted here:__.  If there is a number of shares or
        other units that were registered pursuant to the rule 24e-2 remaining
        unsold at the end of the fiscal year for which this form is filed that
        are available for use by the issuer in future fiscal years, then state
        that number here: __.

7.    Interest Due - if this Form is being filed more than 90 days
      after the end of the issuer's fiscal year (see Instruction D):
                                                                     $0.00

8.    Total of the amount of the registration fee due plus any
      interest due [line 5(viii) plus line 7]:
                                                                     $0.00

9.    Date the registration fee and any interest payment was sent to
      the Commission's lockbox depository:


        Method of Delivery:
          [ ] Wire Transfer
          [ ] Mail or other means

SIGNATURES

This report has been signed below by the following persons on behalf
of the issuer and in the capacities and on the dates indicated.

By (Signature and Title)*

          /s/ Jeffrey P. Fox
          ------------------
              Jeffrey P. Fox
              Treasurer and Principal Financial Officer

Date: March 16, 2007

* Please print the name and the title of the signing officer below the
  signature.