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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001068800-06-001205.txt : 20061017
<SEC-HEADER>0001068800-06-001205.hdr.sgml : 20061017
<ACCEPTANCE-DATETIME>20061017160531
ACCESSION NUMBER:		0001068800-06-001205
CONFORMED SUBMISSION TYPE:	497
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20061017
DATE AS OF CHANGE:		20061017
EFFECTIVENESS DATE:		20061017

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RIVERSOURCE VARIABLE PORTFOLIO INVESTMENT SERIES, INC.
		CENTRAL INDEX KEY:			0000353968
		IRS NUMBER:				411409539
		STATE OF INCORPORATION:			MN
		FISCAL YEAR END:			0831

	FILING VALUES:
		FORM TYPE:		497
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	002-73115
		FILM NUMBER:		061148795

	BUSINESS ADDRESS:	
		STREET 1:		50606 AMERIPRISE FINANCIAL CENTER
		STREET 2:		H27/5228
		CITY:			MINNEAPOLIS
		STATE:			MN
		ZIP:			55474
		BUSINESS PHONE:		6126714321

	MAIL ADDRESS:	
		STREET 1:		50606 AMERIPRISE FINANCIAL CENTER
		STREET 2:		H27/5228
		CITY:			MINNEAPOLIS
		STATE:			MN
		ZIP:			55474

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AXP VARIABLE PORTFOLIO INVESTMENT SERIES INC
		DATE OF NAME CHANGE:	19991126

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	IDS LIFE INVESTMENT SERIES INC
		DATE OF NAME CHANGE:	19981102

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	IDS LIFE CAPITAL RESOURCE FUND INC
		DATE OF NAME CHANGE:	19920703
<SERIES-AND-CLASSES-CONTRACTS-DATA>
<EXISTING-SERIES-AND-CLASSES-CONTRACTS>
<SERIES>
<OWNER-CIK>0000353968
<SERIES-ID>S000003383
<SERIES-NAME>RiverSource Variable Portfolio Mid Cap Growth Fund
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000009304
<CLASS-CONTRACT-NAME>RiverSource VP Mid Cap Growth Fund
</CLASS-CONTRACT>
</SERIES>
</EXISTING-SERIES-AND-CLASSES-CONTRACTS>
</SERIES-AND-CLASSES-CONTRACTS-DATA>
</SEC-HEADER>
<DOCUMENT>
<TYPE>497
<SEQUENCE>1
<FILENAME>vp-midcap_497.txt
<DESCRIPTION>RIVERSOURCE VP INVESTMENT SERIES, INC.
<TEXT>
<PAGE>

                        Supplement Dated Oct. 17, 2006
                     to the Prospectus Dated Oct. 28, 2005
        of RiverSource(SM) Variable Portfolio Funds S-6466-99 Y (10/05)

Effective Oct. 17, 2006, Portfolio Manager subsection of the Manager section
for RiverSource Variable Portfolio - Mid Cap Growth Fund has been revised to
read as follows:

John K. Schonberg, CFA, Interim Portfolio Manager

o Managed the Fund since 2006.
o Equity Team Leader/Product Specialist and Interim Leader of Risk Management.
o Joined RiverSource Investments in 1997.
o Began investment career in 1988.
o BS, University of Nebraska.

The rest of the section remains the same.

S-6466-88 A (10/06)

<PAGE>

     STATEMENT OF ADDITIONAL INFORMATION SUPPLEMENT
     DATED OCT. 17, 2006

<TABLE>
<CAPTION>
     FUND NAME                                                                 SAI DATE AND FORM #
     --------------------------------------------------------------------------------------------------------------
     <S>                                                                       <C>
     RiverSource(SM) Variable Portfolio -- Mid Cap Growth Fund                 (April 24, 2006) S-6466-20 AA
</TABLE>


     Effective Oct. 17, 2006, Table 17. Portfolio Managers, has been revised as
     follows:

<TABLE>
                                                    TABLE 17. PORTFOLIO MANAGERS
- ------------------------------------------------------------------------------------------------------------------------------------
<CAPTION>
                                                                                                             POTENTIAL
                                             OTHER ACCOUNTS MANAGED (excluding the fund)        OWNERSHIP    CONFLICTS  STRUCTURE
     FUND       PORTFOLIO MANAGER        ----------------------------------------------------    OF FUND        OF         OF
                                         NUMBER AND    APPROXIMATE TOTAL    PERFORMANCE BASED    SHARES      INTEREST  COMPENSATION
                                            TYPE          NET ASSETS           ACCOUNTS(a)
                                         OF ACCOUNT*
- ------------------------------------------------------------------------------------------------------------------------------------
<S>             <C>                      <C>           <C>                  <C>                 <C>          <C>       <C>
Mid Cap Growth  John K. Schonberg(b)
- -----------------------------------------------------------------------------------------------------------

- -----------------------------------------------------------------------------------------------------------
                                                                                                                 (1)       (3)
- -----------------------------------------------------------------------------------------------------------

- -----------------------------------------------------------------------------------------------------------

       *  RIC refers to a Registered Investment Company; PIV refers to a Pooled
          Investment Vehicle.
     (a)  Number of accounts for which the advisory fee paid is based in part or
          wholly on performance and the aggregate net assets in those accounts.
     (b)  The portfolio manager began managing the fund as of Oct. 17, 2006,
          which was after the fund's most recent fiscal year end; therefore
          reporting information is not yet available.
</TABLE>


The rest of this section remains the same.


S-6466-89 A (10/06)


</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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