CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Cash flows from operating activities:
Net income (loss)	$ (15,191)	$ (11,985)	$ 6,668
Reconciliation of net income (loss) to net cash provided by (used in) operating activities:
Depreciation and amortization of fixed assets	1,711	946	560
Amortization of license fee	0	0	100
Provision for write down of inventory	2,132	1,400	50
Provision for bad debt	1,767	327	0
Issuance of stock to consultant	0	189	0
Stock based compensation	3,295	2,999	2,273
Amortization of debt issuance costs	943	828	1,132
Amortization of intangibles	2,930	2,833	514
Foreign currency exchange loss (gain)	(7,719)	936	(109)
Amortization of debt discount on convertible 3.75% senior notes	8,643	7,599	6,680
Change in the fair value of derivative liability	0	0	(23,144)
Loss on disposal of property/impairment	113	16	0
Changes in operating assets and liabilities:
Accounts receivable	1,894	(8,008)	1,250
Inventories	(5,275)	(5,042)	(3,578)
Prepaid expenses and other current receivables	(748)	3,427	(5,408)
Other assets	194	316	(14)
Accounts payable and accrued expenses	5,711	2,897	(2,849)
Deferred income	0	(476)	362
Net cash used in operating activities	400	(798)	(15,513)
Cash flows from investing activities:
Capital expenditures	(40,429)	(16,655)	(5,998)
Acquisition of product rights and other related assets	0	0	(35,418)
Product acquisition costs, net	0	(3,421)	(11,652)
Net cash used in investing activities	(40,429)	(20,076)	(53,068)
Cash flows from financing activities:
Proceeds from issuance of stock, net	0	0	(3)
Principal payments on note payable, bank	0	0	(3,160)
Proceeds from exercise of common stock options and warrants	269	96	165
Principal payments on capital lease obligations	0	(70)	(132)
Payment (recovery) from stockholder, net	0	(36)	19
Net cash provided by (used in) financing activities	269	(10)	(3,111)
Effect of exchange rate on cash and cash equivalents	446	(301)	0
Net decrease in cash and cash equivalents	(39,760)	(20,884)	(71,692)
Cash and cash equivalents at beginning of year	66,006	87,191	158,883
Cash and cash equivalents at end of year	26,692	66,006	87,191
Supplemental Cash flow information:
Cash payments for interest	5,391	5,393	5,517
Cash payments for income taxes	126	113	123
Non cash investing and financing transactions:
Reclassification of derivative liability to equity	0	0	18,256
Acquisition of capital expenditures in accounts payable and accrued expenses	3,186	1,805	0
Capitalized stock compensation in capital expenditures	127	91	0
Issuance of stock to consultant	0	189	31
Restricted Stock
Non cash investing and financing transactions:
Issuance of restricted stock	$ 0	$ 0	$ 347