PROMISSORY NOTE

                                              Baltimore, Maryland
                                                February 20, 2002

$100,000.00

     THIS PROMISSORY NOTE (the "Note") is made this 2018th day of
February, 2002, by C.W. GILLULY ("Borrower") for the benefit of
ENHANCE PHARMACEUTICALS, INC., a Maryland corporation ("Lender").

     FOR VALUE RECEIVED, the undersigned Borrower hereby promises
to pay to the order of Lender, and any successor or assignee or
other lawful owner of this Note, the principal sum of One Hundred
Thousand Dollars ($100,000.00) ("Principal Sum") and to pay
interest from the date hereof on the unpaid Principal Sum at the
rate or rates hereinafter set forth.

     UPON THE TERMS of this Note:

          1.   INTEREST RATE.  Interest shall accrue on the
          unpaid balance of the Principal Sum at the per annum
          rate of FIVE PERCENT (5%) from and after the date of
          this Note.

          2.   CALCULATION OF INTEREST.  All interest on this
          Note shall be calculated on the basis of a 365 day per
          year factor applied to actual days elapsed.

          3.   PAYMENTS.   The Principal Sum and interest shall
          be payable in lawful money of the United States which
          is legal tender for the payment of all debts and dues,
          public and private at the time of payment, or, at the
          option of the Borrower, Borrower may repay the
          Principal Sum, and any interest or other fees due under
          this Note by tendering to Lender the Collateral (as
          defined below).  Borrower shall pay this Note in full
          upon not less than five (5) days prior written notice,
          or if not sooner demanded, by February 19, 2003 (the
          "Maturity Date").

          4.   PREPAYMENT.  Borrower may prepay the Note at any
          time without penalty.  In lieu of payment, Lender may
          forfeit the Collateral which secures this Note, and
          extinguish all rights of Lender, including to
          indemnification and recoupment of costs as stated
          below.  Lender retains the option to demand repayment
          of the Note within five (5) days notice, in which case
          Borrower may surrender the Collateral, or tender
          payment in cash.

          5.   PAYMENT OF COSTS.  If, after any default by
          Borrower in making any payment when due hereunder, any
          suit or action is instituted to collect any or all of
          the Principal Sum, any late fees accrued thereon or any
          other sum falling due under the provisions of this
          Note, or if this Note is placed in the hands of any
          attorney for collection, Borrower hereby agrees to pay
          all reasonable costs thereby incurred by the lender,
          including that of reasonable attorneys' fees, all of
          which shall be added to and become part of the debt
          evidence hereby.

          6.   APPLICABLE LAW.  This Note shall be governed by
          Maryland law.

          7.   NOTICES.  Any notice required to be given
          hereunder shall be deemed to have been properly given
          if by a written communication given by hand delivery,
          by facsimile or by certified mail, postage prepaid,
          return receipt requested to:

     If to Borrower: C.W. Gilluly
                     415 First Street, SE
                     Washington, D.C.20003-1827
                     (202) 546-4367
                     (202) 544-8384 fax

     With a Copy to: Jocelyn W. Brittin, Esq.
                     Holland & Knight LLC
                     1600 Tysons Blvd, Suite 700
                     McLean, VA 22102

     If to Lender:   David Schmickel
                     1325 Park Avenue
                     Baltimore, Maryland 21217

     With a Copy to: John H. Denick, Esq.
                     Denick & Hyman, P.A.
                     20 South Charles Street, Suite 300
                     Baltimore, Maryland 21201

          8.   SECURITY.  This Note shall be secured by the Comtex
          News Network, Inc. ("Comtex") stock to be purchased by
          Borrower, as described in the accompanying Pledge
          Agreement (the "Collateral").

          9.   EXTENSIONS.  The Maturity Date of this Note and/or
          any other date by which payment is required to be made
          hereunder may be extended by the Lender from time to
          time in its sole discretion, without in any way
          altering or impairing the Borrower's or any guarantor's
          liability under this Note.

     IN WITNESS WHEREOF, Borrower has caused this Note to be
executed, sealed and delivered as of the day and year first
written above.

WITNESS:


                                   /S/ C.W. GILLULY
_________________________________  _____________________________
                                   C.W. Gilluly