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Summary of Option Activities (Detail) - $ / shares
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]      
Outstanding Options, Number of shares, beginning balance 8,133,176    
Granted, Number of Shares 2,589,966    
Exercised, Number of Shares (1,534,741)    
Expired, Number of Shares (551,750)    
Cancelled, Number of Shares (397,685)    
Outstanding Options, Number of shares, ending balance 8,238,966    
Outstanding options vested and exercisable, Number of Shares 2,522,906 2,551,267 3,724,179
Outstanding Options, Average Option Price, beginning balance $ 124.52    
Granted, Average Option Price 70.36    
Exercised, Average Option Price 118.99    
Expired, Average Option Price 117.30    
Cancelled, Average Option Price 114.79    
Outstanding Options, Average Option Price, ending balance 109.47    
Outstanding options vested and exercisable, Average Option Price $ 124.62 $ 119.86 $ 106.77