NPORT-EX 2 QTLY_63_20230531.htm 010 - Quarterly Front Cover
Quarterly Holdings Report
for
Fidelity® Select Portfolios®
Health Care Portfolio
May 31, 2023
HEA-NPRT1-0723
1.802174.119
Common Stocks - 97.7%
 
 
Shares
Value ($)
 
Biotechnology - 18.4%
 
 
 
Biotechnology - 18.4%
 
 
 
Acelyrin, Inc. (a)(b)
 
800,000
14,480,000
Akero Therapeutics, Inc. (a)
 
1,000,000
44,580,000
Alnylam Pharmaceuticals, Inc. (a)
 
130,000
24,051,300
Ambrx Biopharma, Inc. ADR (a)
 
354,700
5,235,372
Apellis Pharmaceuticals, Inc. (a)
 
520,000
44,642,000
Arcellx, Inc. (a)
 
500,000
22,075,000
Arcus Biosciences, Inc. (a)
 
430,148
8,835,240
Arcutis Biotherapeutics, Inc. (a)
 
1,100,000
8,261,000
Argenx SE ADR (a)
 
465,000
180,745,500
Ascendis Pharma A/S sponsored ADR (a)
 
900,000
78,273,000
Avidity Biosciences, Inc. (a)
 
500,000
5,310,000
Beam Therapeutics, Inc. (a)(b)
 
400,000
12,760,000
Blueprint Medicines Corp. (a)
 
670,000
37,868,400
Caris Life Sciences, Inc. (c)(d)
 
1,420,479
7,954,682
Celldex Therapeutics, Inc. (a)
 
800,000
25,440,000
Cerevel Therapeutics Holdings (a)
 
1,370,364
44,673,866
Cytokinetics, Inc. (a)
 
1,500,000
56,535,000
Generation Bio Co. (a)
 
509,353
1,782,736
Janux Therapeutics, Inc. (a)
 
500,000
5,810,000
Karuna Therapeutics, Inc. (a)
 
284,951
64,555,649
Keros Therapeutics, Inc. (a)
 
540,000
25,844,400
Legend Biotech Corp. ADR (a)
 
1,700,000
109,089,000
Morphic Holding, Inc. (a)
 
400,000
23,000,000
Nuvalent, Inc. Class A (a)
 
600,000
25,260,000
Poseida Therapeutics, Inc. (a)
 
1,927,613
4,375,682
PTC Therapeutics, Inc. (a)
 
580,000
24,342,600
Regeneron Pharmaceuticals, Inc. (a)
 
350,000
257,446,000
Relay Therapeutics, Inc. (a)
 
86,286
961,226
Repligen Corp. (a)
 
520,000
87,318,400
Sarepta Therapeutics, Inc. (a)
 
250,000
30,900,000
Shattuck Labs, Inc. (a)
 
1,162,800
3,034,908
uniQure B.V. (a)
 
670,000
12,924,300
Vaxcyte, Inc. (a)
 
1,280,000
63,385,600
Vertex Pharmaceuticals, Inc. (a)
 
150,000
48,535,500
Xencor, Inc. (a)
 
1,400,000
37,940,000
Xenon Pharmaceuticals, Inc. (a)
 
800,000
30,824,000
Zai Lab Ltd. (a)(e)
 
5,000,000
16,325,788
Zentalis Pharmaceuticals, Inc. (a)
 
1,280,000
33,331,200
 
 
 
1,528,707,349
Health Care Equipment & Supplies - 21.3%
 
 
 
Health Care Equipment - 21.3%
 
 
 
Boston Scientific Corp. (a)
 
10,850,000
558,558,000
Insulet Corp. (a)
 
660,000
181,005,000
Intuitive Surgical, Inc. (a)
 
210,000
64,646,400
iRhythm Technologies, Inc. (a)
 
440,000
50,278,800
Masimo Corp. (a)
 
1,430,000
231,431,200
Nevro Corp. (a)
 
600,000
16,536,000
Novocure Ltd. (a)
 
500,000
35,905,000
Outset Medical, Inc. (a)
 
1,000,000
20,830,000
Penumbra, Inc. (a)
 
1,180,000
362,661,200
PROCEPT BioRobotics Corp. (a)
 
600,000
20,070,000
ResMed, Inc.
 
580,000
122,258,200
Stryker Corp.
 
300,000
82,674,000
Tandem Diabetes Care, Inc. (a)
 
850,000
22,091,500
 
 
 
1,768,945,300
Health Care Providers & Services - 25.9%
 
 
 
Health Care Facilities - 2.6%
 
 
 
Acadia Healthcare Co., Inc. (a)
 
1,000,000
70,630,000
Surgery Partners, Inc. (a)
 
3,858,785
144,627,262
The Oncology Institute, Inc. (a)
 
1,699,893
726,704
 
 
 
215,983,966
Health Care Services - 6.9%
 
 
 
agilon health, Inc. (a)(b)
 
10,203,500
202,845,580
Cigna Group
 
828,000
204,855,480
CVS Health Corp.
 
800,000
54,424,000
LifeStance Health Group, Inc. (a)
 
4,800,000
39,312,000
Privia Health Group, Inc. (a)
 
2,800,000
69,860,000
 
 
 
571,297,060
Managed Health Care - 16.4%
 
 
 
Alignment Healthcare, Inc. (a)
 
3,800,000
22,306,000
Centene Corp. (a)
 
3,350,000
209,073,500
Humana, Inc.
 
490,000
245,916,300
Molina Healthcare, Inc. (a)
 
145,000
39,715,500
UnitedHealth Group, Inc.
 
1,730,000
842,925,199
 
 
 
1,359,936,499
TOTAL HEALTH CARE PROVIDERS & SERVICES
 
 
2,147,217,525
Health Care Technology - 1.9%
 
 
 
Health Care Technology - 1.9%
 
 
 
Doximity, Inc. (a)(b)
 
690,000
21,162,300
Evolent Health, Inc. (a)
 
841,400
24,518,396
Evolent Health, Inc. (c)
 
1,178,600
32,627,184
Medlive Technology Co. Ltd. (f)
 
970,500
853,941
Phreesia, Inc. (a)
 
1,080,000
32,421,600
Veeva Systems, Inc. Class A (a)
 
260,000
43,082,000
 
 
 
154,665,421
Life Sciences Tools & Services - 15.9%
 
 
 
Life Sciences Tools & Services - 15.9%
 
 
 
10X Genomics, Inc. (a)
 
1,000,000
52,460,000
10X Genomics, Inc. Class B (a)(f)
 
500,000
26,230,000
Bruker Corp.
 
1,120,000
77,392,000
Danaher Corp.
 
2,080,000
477,609,600
IQVIA Holdings, Inc. (a)
 
585,000
115,192,350
Lonza Group AG
 
69,000
43,138,732
Olink Holding AB ADR (a)
 
1,159,712
22,591,190
Sartorius Stedim Biotech
 
170,000
44,628,713
Thermo Fisher Scientific, Inc.
 
775,000
394,056,500
West Pharmaceutical Services, Inc.
 
190,000
63,579,700
 
 
 
1,316,878,785
Personal Care Products - 0.2%
 
 
 
Personal Care Products - 0.2%
 
 
 
The Beauty Health Co. (a)(b)
 
482,705
3,880,948
The Beauty Health Co. (a)(c)
 
1,800,000
14,472,000
 
 
 
18,352,948
Pharmaceuticals - 14.1%
 
 
 
Pharmaceuticals - 14.1%
 
 
 
Arvinas Holding Co. LLC (a)
 
690,000
15,062,700
AstraZeneca PLC (United Kingdom)
 
1,500,000
218,475,937
Eli Lilly & Co.
 
1,050,000
450,933,000
Enliven Therapeutics, Inc. (a)(b)
 
400,000
7,320,000
Merck & Co., Inc.
 
1,450,000
160,094,500
Novo Nordisk A/S Series B
 
535,000
86,098,107
Pharvaris BV (a)
 
620,000
5,301,000
Royalty Pharma PLC
 
4,200,000
137,508,000
UCB SA
 
600,000
52,282,037
Ventyx Biosciences, Inc. (a)
 
800,400
27,589,788
Verona Pharma PLC ADR (a)
 
600,000
12,912,000
 
 
 
1,173,577,069
 
TOTAL COMMON STOCKS
 (Cost $5,527,243,691)
 
 
 
8,108,344,397
 
 
 
 
Preferred Stocks - 1.3%
 
 
Shares
Value ($)
 
Convertible Preferred Stocks - 1.2%
 
 
 
Biotechnology - 0.7%
 
 
 
Biotechnology - 0.7%
 
 
 
Asimov, Inc. Series B (a)(c)(d)
 
101,438
4,908,585
Caris Life Sciences, Inc. Series D (a)(c)(d)
 
3,206,021
17,953,718
Cleerly, Inc. Series C (c)(d)
 
1,285,367
15,013,087
Element Biosciences, Inc. Series C (a)(c)(d)
 
572,265
9,413,759
ElevateBio LLC Series C (a)(c)(d)
 
254,900
1,070,580
Inscripta, Inc. Series E (a)(c)(d)
 
1,282,228
5,423,824
 
 
 
53,783,553
Financial Services - 0.1%
 
 
 
Specialized Finance - 0.1%
 
 
 
Saluda Medical, Inc. Series E (c)(d)
 
1,155,359
9,312,194
 
 
 
 
Health Care Providers & Services - 0.0%
 
 
 
Health Care Services - 0.0%
 
 
 
dMed Biopharmaceutical Co. Ltd. Series C (a)(c)(d)
 
380,451
3,374,600
 
 
 
 
Health Care Technology - 0.3%
 
 
 
Health Care Technology - 0.3%
 
 
 
Aledade, Inc.:
 
 
 
  Series B1(a)(c)(d)
 
201,220
10,085,146
  Series E1(c)(d)
 
56,664
2,840,000
Omada Health, Inc. Series E (a)(c)(d)
 
2,153,073
6,975,957
Wugen, Inc. Series B (a)(c)(d)
 
454,342
2,271,710
 
 
 
22,172,813
Pharmaceuticals - 0.1%
 
 
 
Pharmaceuticals - 0.1%
 
 
 
Aristea Therapeutics, Inc. Series B (a)(c)(d)
 
1,037,400
5,716,074
Galvanize Therapeutics Series B (a)(c)(d)
 
3,696,429
6,246,965
 
 
 
11,963,039
TOTAL CONVERTIBLE PREFERRED STOCKS
 
 
100,606,199
Nonconvertible Preferred Stocks - 0.1%
 
 
 
Financial Services - 0.1%
 
 
 
Diversified Financial Services - 0.1%
 
 
 
Thriveworks TopCo LLC Series B (a)(c)(d)(g)
 
473,270
7,099,050
 
 
 
 
 
TOTAL PREFERRED STOCKS
 (Cost $142,088,836)
 
 
 
107,705,249
 
 
 
 
Money Market Funds - 2.2%
 
 
Shares
Value ($)
 
Fidelity Cash Central Fund 5.14% (h)
 
85,162,186
85,179,218
Fidelity Securities Lending Cash Central Fund 5.14% (h)(i)
 
95,501,533
95,511,083
 
TOTAL MONEY MARKET FUNDS
 (Cost $180,688,551)
 
 
180,690,301
 
 
 
 
 
TOTAL INVESTMENT IN SECURITIES - 101.2%
 (Cost $5,850,021,078)
 
 
 
8,396,739,947
NET OTHER ASSETS (LIABILITIES) - (1.2)%  
(103,173,852)
NET ASSETS - 100.0%
8,293,566,095
 
 
Legend
 
(a)
Non-income producing
 
(b)
Security or a portion of the security is on loan at period end.
 
(c)
Restricted securities (including private placements) - Investment in securities not registered under the Securities Act of 1933 (excluding 144A issues).  At the end of the period, the value of restricted securities (excluding 144A issues) amounted to $162,759,115 or 2.0% of net assets.
 
(d)
Level 3 security
 
(e)
Affiliated company
 
(f)
Security exempt from registration under Rule 144A of the Securities Act of 1933.  These securities may be resold in transactions exempt from registration, normally to qualified institutional buyers. At the end of the period, the value of these securities amounted to $27,083,941 or 0.3% of net assets.
 
(g)
Investment is owned by a wholly-owned subsidiary (Subsidiary) that is treated as a corporation for U.S. tax purposes.
 
(h)
Affiliated fund that is generally available only to investment companies and other accounts managed by Fidelity Investments. The rate quoted is the annualized seven-day yield of the fund at period end. A complete unaudited listing of the fund's holdings as of its most recent quarter end is available upon request. In addition, each Fidelity Central Fund's financial statements are available on the SEC's website or upon request.
 
(i)
Investment made with cash collateral received from securities on loan.
 
 
 
Additional information on each restricted holding is as follows:
Security
Acquisition Date
Acquisition Cost ($)
 
Aledade, Inc. Series B1
5/07/21
7,704,855
 
 
 
Aledade, Inc. Series E1
5/20/22
2,822,683
 
 
 
Aristea Therapeutics, Inc. Series B
10/06/20
5,719,912
 
 
 
Asimov, Inc. Series B
10/29/21
9,401,345
 
 
 
Caris Life Sciences, Inc.
10/06/22
7,954,682
 
 
 
Caris Life Sciences, Inc. Series D
5/11/21
25,968,770
 
 
 
Cleerly, Inc. Series C
7/08/22
15,142,394
 
 
 
dMed Biopharmaceutical Co. Ltd. Series C
12/01/20
5,403,602
 
 
 
Element Biosciences, Inc. Series C
6/21/21
11,763,880
 
 
 
ElevateBio LLC Series C
3/09/21
1,069,306
 
 
 
Evolent Health, Inc.
3/28/23
34,179,400
 
 
 
Galvanize Therapeutics Series B
3/29/22
6,399,572
 
 
 
Inscripta, Inc. Series E
3/30/21
11,322,073
 
 
 
Omada Health, Inc. Series E
12/22/21
12,908,103
 
 
 
Saluda Medical, Inc. Series E
4/06/23
9,328,137
 
 
 
The Beauty Health Co.
12/08/20
18,000,000
 
 
 
Thriveworks TopCo LLC Series B
7/23/21 - 2/25/22
13,610,827
 
 
 
Wugen, Inc. Series B
7/09/21
3,523,377
 
 
 
 
 
Affiliated Central Funds
 
Fiscal year to date information regarding the Fund's investments in Fidelity Central Funds, including the ownership percentage, is presented below.
 
 
Affiliate
Value,
beginning
of period ($)
Purchases ($)
Sales
Proceeds ($)
Dividend
Income ($)
Realized
Gain (loss) ($)
Change in
Unrealized
appreciation
(depreciation) ($)
Value,
end
of period ($)
% ownership,
end
of period
Fidelity Cash Central Fund 5.14%
-
503,597,873
418,418,655
580,240
-
-
85,179,218
0.2%
Fidelity Securities Lending Cash Central Fund 5.14%
189,954,325
148,266,459
242,709,701
392,620
-
-
95,511,083
0.3%
Total
189,954,325
651,864,332
661,128,356
972,860
-
-
180,690,301
 
 
 
 
 
 
 
 
 
 
Amounts in the dividend income column in the above table include any capital gain distributions from underlying funds.
 
Amounts in the dividend income column for Fidelity Securities Lending Cash Central Fund represents the income earned on investing cash collateral, less rebates paid to borrowers and any lending agent fees associated with the loan, plus any premium payments received for lending certain types of securities.
 
Other Affiliated Issuers
An affiliated company is a company in which the Fund has ownership of at least 5% of the voting securities. Fiscal year to date transactions with companies which are or were affiliates are presented in the table below. Certain corporate actions, such as mergers, are excluded from the amounts in this table if applicable. A dash in the Value end of period ($) column means either the issuer is no longer held at period end, or the issuer is held at period end but is no longer an affiliate.
Affiliate
Value,
beginning
of period ($)
Purchases ($)
Sales
Proceeds ($)
Dividend
Income ($)
Realized
Gain (loss) ($)
Change in
Unrealized
appreciation
(depreciation) ($)
Value,
end
of period ($)
Zai Lab Ltd.
24,532,952
1,003,217
6,666,665
-
(8,304,126)
5,760,410
16,325,788
Total
24,532,952
1,003,217
6,666,665
-
(8,304,126)
5,760,410
16,325,788
 
 
 
Investment Valuation
Investments are valued as of 4:00 p.m. Eastern time on the last calendar day of the period. Securities transactions are accounted for as of trade date. The Board of Trustees (the Board) has designated the Fund's investment adviser as the valuation designee responsible for the fair valuation function and performing fair value determinations as needed. The investment adviser has established a Fair Value Committee (the Committee) to carry out the day-to-day fair valuation responsibilities and has adopted policies and procedures to govern the fair valuation process and the activities of the Committee. In accordance with these fair valuation policies and procedures, which have been approved by the Board, the Fund attempts to obtain prices from one or more third party pricing services or brokers to value its investments. When current market prices, quotations or currency exchange rates are not readily available or reliable, investments will be fair valued in good faith by the Committee, in accordance with the policies and procedures. Factors used in determining fair value vary by investment type and may include market or investment specific events, transaction data, estimated cash flows, and market observations of comparable investments. The frequency that the fair valuation procedures are used cannot be predicted and they may be utilized to a significant extent. The Committee manages the Fund's fair valuation practices and maintains the fair valuation policies and procedures. The Fund's investment adviser reports to the Board information regarding the fair valuation process and related material matters.   
 
The inputs to valuation techniques used to value investments are categorized into a disclosure hierarchy consisting of three levels as shown below:
 
Level 1 - Unadjusted quoted prices in active markets for identical investments
Level 2 - other significant observable inputs (including quoted prices for similar investments, interest rates, prepayment speeds, etc.)
Level 3 - unobservable inputs (including the Fund's own assumptions based on the best information available)
 
Valuation techniques used to value investments by major category are as follows:
Equity securities, including restricted securities, for which market quotations are readily available, are valued at the last reported sale price or official closing price as reported by a third party pricing service on the primary market or exchange on which they are traded and are categorized as Level 1 in the hierarchy. In the event there were no sales during the day or closing prices are not available, securities are valued at the last quoted bid price or may be valued using the last available price and are generally categorized as Level 2 in the hierarchy. For any foreign equity securities, when market or security specific events arise, comparisons to the valuation of American Depositary Receipts (ADRs), futures contracts, Exchange-Traded Funds (ETFs) and certain indexes as well as quoted prices for similar securities may be used and would be categorized as Level 2 in the hierarchy. For equity securities, including restricted securities, where observable inputs are limited, assumptions about market activity and risk are used and these securities may be categorized as Level 3 in the hierarchy.
 
Securities, including private placements or other restricted securities, for which observable inputs are not available are valued using alternate valuation approaches, including the market approach, the income approach and cost approach, and are categorized as Level 3 in the hierarchy. The market approach considers factors including the price of recent investments in the same or a similar security or financial metrics of comparable securities. The income approach considers factors including expected future cash flows, security specific risks and corresponding discount rates. The cost approach considers factors including the value of the security's underlying assets and liabilities.
 
Investments in any open-end mutual funds are valued at their closing net asset value (NAV) each business day and are categorized as Level 1 in the hierarchy.
 
Changes in valuation techniques may result in transfers in or out of an assigned level within the disclosure hierarchy.
 
For additional information on the Fund's significant accounting policies, please refer to the Fund's most recent semiannual or annual shareholder report.
The fund's schedule of investments as of the date on the cover of this report has not been audited. This report is provided for the general information of the fund's shareholders. For more information regarding the fund and its holdings, please see the fund's most recent prospectus and annual report.
 
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