NPORT-EX 2 QTLY_63_20200531.htm

Quarterly Holdings Report
for

Fidelity® Select Portfolio®

Health Care Portfolio

May 31, 2020







HEA-QTLY-0720
1.802174.116





Schedule of Investments May 31, 2020 (Unaudited)

Showing Percentage of Net Assets

Common Stocks - 97.9%   
 Shares Value 
Biotechnology - 25.5%   
Biotechnology - 25.5%   
Acceleron Pharma, Inc. (a) 930,000 $91,911,900 
ADC Therapeutics SA (a) 573,665 21,196,922 
Alnylam Pharmaceuticals, Inc. (a) 800,000 108,216,000 
Amgen, Inc. 500,000 114,850,000 
Aprea Therapeutics, Inc. 600,000 16,116,000 
Arcutis Biotherapeutics, Inc. (a) 600,000 20,130,000 
Argenx SE ADR (a) 596,986 130,919,030 
Ascendis Pharma A/S sponsored ADR (a) 874,790 127,273,197 
BeiGene Ltd. ADR (a) 260,000 43,040,400 
BELLUS Health, Inc. (a) 1,200,000 12,588,000 
BioNTech SE ADR (a) 1,160,000 57,454,800 
Black Diamond Therapeutics, Inc. (a) 230,000 8,981,500 
Blueprint Medicines Corp. (a) 400,000 26,056,000 
Denali Therapeutics, Inc. (a)(b) 360,000 10,018,800 
FibroGen, Inc. (a) 900,000 30,096,000 
G1 Therapeutics, Inc. (a) 926,588 15,724,198 
Gritstone Oncology, Inc. (a) 600,000 3,876,000 
Innovent Biologics, Inc. (a)(c) 6,700,000 36,792,903 
Insmed, Inc. (a) 1,313,811 31,912,469 
Intercept Pharmaceuticals, Inc. (a) 342,000 24,712,920 
Kura Oncology, Inc. (a) 1,280,000 21,875,200 
Moderna, Inc. (a) 280,000 17,220,000 
Momenta Pharmaceuticals, Inc. (a) 500,000 15,740,000 
Morphic Holding, Inc. 259,784 5,398,312 
Neurocrine Biosciences, Inc. (a) 900,000 112,284,000 
ORIC Pharmaceuticals, Inc. (a)(b) 500,000 14,510,000 
Passage Bio, Inc. 600,000 13,218,000 
Principia Biopharma, Inc. (a) 786,924 50,276,574 
Regeneron Pharmaceuticals, Inc. (a) 628,000 384,844,680 
Revolution Medicines, Inc. 1,160,000 35,635,200 
Sage Therapeutics, Inc. (a) 131,179 4,685,714 
Sarepta Therapeutics, Inc. (a) 1,020,000 155,315,400 
Scholar Rock Holding Corp. (a) 100,618 1,851,371 
TG Therapeutics, Inc. (a) 1,700,000 31,705,000 
Turning Point Therapeutics, Inc. (a) 400,000 27,700,000 
uniQure B.V. (a) 400,000 26,864,000 
Vertex Pharmaceuticals, Inc. (a) 800,000 230,368,000 
Viela Bio, Inc. 900,000 42,210,000 
Viking Therapeutics, Inc. (a)(b) 1,160,000 8,294,000 
Xencor, Inc. (a) 1,200,000 36,300,000 
Zentalis Pharmaceuticals, Inc. (b) 520,000 27,154,400 
Zymeworks, Inc. (a) 866,245 33,021,259 
  2,228,338,149 
Electronic Equipment & Components - 0.3%   
Electronic Equipment & Instruments - 0.3%   
FLIR Systems, Inc. 500,000 23,100,000 
Health Care Equipment & Supplies - 21.7%   
Health Care Equipment - 20.8%   
Atricure, Inc. (a) 1,000,000 47,810,000 
Becton, Dickinson & Co. 1,600,000 395,088,000 
Boston Scientific Corp. (a) 10,000,000 379,900,000 
Danaher Corp. 940,000 156,613,400 
DexCom, Inc. (a) 70,000 26,481,700 
Genmark Diagnostics, Inc. (a) 2,684,874 25,479,454 
Insulet Corp. (a) 1,000,000 188,570,000 
Intuitive Surgical, Inc. (a) 308,000 178,649,240 
Masimo Corp. (a) 650,000 156,123,500 
Nevro Corp. (a) 118,000 14,820,800 
Penumbra, Inc. (a) 1,028,000 177,247,760 
Shockwave Medical, Inc. (a) 610,000 26,846,100 
Tandem Diabetes Care, Inc. (a) 600,000 49,890,000 
  1,823,519,954 
Health Care Supplies - 0.9%   
Quidel Corp. (a) 440,000 77,000,000 
TOTAL HEALTH CARE EQUIPMENT & SUPPLIES  1,900,519,954 
Health Care Providers & Services - 23.6%   
Health Care Distributors & Services - 0.4%   
EBOS Group Ltd. 2,280,000 31,136,820 
Health Care Services - 5.8%   
1Life Healthcare, Inc. 1,639,892 50,320,086 
Alignment Healthcare Partners unit (d)(e) 2,145,460 38,185,541 
Cigna Corp. 2,140,000 422,264,800 
  510,770,427 
Managed Health Care - 17.4%   
Anthem, Inc. 400,000 117,644,000 
Centene Corp. (a) 4,450,000 294,812,500 
Humana, Inc. 1,000,000 410,650,000 
UnitedHealth Group, Inc. 2,300,000 701,155,000 
  1,524,261,500 
TOTAL HEALTH CARE PROVIDERS & SERVICES  2,066,168,747 
Health Care Technology - 1.2%   
Health Care Technology - 1.2%   
Castlight Health, Inc. (a) 1,845,550 1,453,740 
Castlight Health, Inc. Class B (a) 4,000,000 3,150,800 
Inspire Medical Systems, Inc. (a) 690,000 56,262,600 
Veeva Systems, Inc. Class A (a) 220,000 48,151,400 
  109,018,540 
Life Sciences Tools & Services - 4.3%   
Life Sciences Tools & Services - 4.3%   
10X Genomics, Inc. Class B (c) 2,400,000 187,128,000 
Bruker Corp. 2,024,500 87,620,360 
Lonza Group AG 200,000 98,764,141 
  373,512,501 
Pharmaceuticals - 20.9%   
Pharmaceuticals - 20.9%   
Arvinas Holding Co. LLC (a) 600,000 19,962,000 
AstraZeneca PLC (United Kingdom) 3,900,000 420,029,208 
Bristol-Myers Squibb Co. 670,000 40,012,400 
Dechra Pharmaceuticals PLC 825,901 28,376,059 
Eli Lilly & Co. 2,300,000 351,785,000 
MyoKardia, Inc. (a) 724,250 74,083,533 
Nektar Therapeutics (a)(b) 2,080,000 45,136,000 
Roche Holding AG (participation certificate) 1,500,000 520,682,660 
RPI International Holdings LP (d)(e) 199,753 40,444,989 
Sanofi SA 2,600,000 254,318,489 
Theravance Biopharma, Inc. (a)(b) 1,296,835 32,745,084 
  1,827,575,422 
Professional Services - 0.3%   
Research & Consulting Services - 0.3%   
Clarivate Analytics PLC (a) 1,000,000 22,890,000 
Software - 0.1%   
Application Software - 0.1%   
Outset Medical, Inc. (a)(d)(e) 3,279,404 8,296,892 
TOTAL COMMON STOCKS   
(Cost $5,268,675,710)  8,559,420,205 
Preferred Stocks - 1.0%   
Convertible Preferred Stocks - 0.6%   
Biotechnology - 0.0%   
Biotechnology - 0.0%   
Generation Bio:   
Series B (a)(d) 130,800 793,956 
Series C (d) 124,500 664,830 
  1,458,786 
Pharmaceuticals - 0.4%   
Pharmaceuticals - 0.4%   
Harmony Biosciences II, Inc.:   
Series A (a)(d)(e) 10,935,215 26,463,220 
Series C (d)(e) 1,845,926 4,467,141 
  30,930,361 
Software - 0.2%   
Application Software - 0.2%   
Outset Medical, Inc.:   
Series B (a)(d)(e) 8,159,125 18,602,805 
Series E (d)(e) 840,909 2,127,500 
  20,730,305 
TOTAL CONVERTIBLE PREFERRED STOCKS  53,119,452 
Nonconvertible Preferred Stocks - 0.4%   
Health Care Providers & Services - 0.4%   
Health Care Services - 0.4%   
Oak Street Health LLC Series III-E (d)(e)(f) 185,552 37,240,286 
TOTAL PREFERRED STOCKS   
(Cost $58,615,509)  90,359,738 
Money Market Funds - 1.3%   
Fidelity Cash Central Fund 0.11% (g) 56,757,010 56,768,362 
Fidelity Securities Lending Cash Central Fund 0.10% (g)(h) 55,407,734 55,413,275 
TOTAL MONEY MARKET FUNDS   
(Cost $112,179,466)  112,181,637 
TOTAL INVESTMENT IN SECURITIES - 100.2%   
(Cost $5,439,470,685)  8,761,961,580 
NET OTHER ASSETS (LIABILITIES) - (0.2)%  (19,787,812) 
NET ASSETS - 100%  $8,742,173,768 

Legend

 (a) Non-income producing

 (b) Security or a portion of the security is on loan at period end.

 (c) Security exempt from registration under Rule 144A of the Securities Act of 1933. These securities may be resold in transactions exempt from registration, normally to qualified institutional buyers. At the end of the period, the value of these securities amounted to $223,920,903 or 2.6% of net assets.

 (d) Restricted securities (including private placements) - Investment in securities not registered under the Securities Act of 1933 (excluding 144A issues). At the end of the period, the value of restricted securities (excluding 144A issues) amounted to $177,287,160 or 2.0% of net assets.

 (e) Level 3 security

 (f) Investment is owned by a wholly-owned subsidiary (Subsidiary) that is treated as a corporation for U.S. tax purposes.

 (g) Affiliated fund that is generally available only to investment companies and other accounts managed by Fidelity Investments. The rate quoted is the annualized seven-day yield of the fund at period end. A complete unaudited listing of the fund's holdings as of its most recent quarter end is available upon request. In addition, each Fidelity Central Fund's financial statements are available on the SEC's website or upon request.

 (h) Includes investment made with cash collateral received from securities on loan.

Additional information on each restricted holding is as follows:

Security Acquisition Date Acquisition Cost 
Alignment Healthcare Partners unit 2/28/20 $26,000,002 
Generation Bio Series B 2/21/18 $1,196,258 
Generation Bio Series C 1/9/20 $696,129 
Harmony Biosciences II, Inc. Series A 9/22/17 $10,935,215 
Harmony Biosciences II, Inc. Series C 8/9/19 $3,618,015 
Oak Street Health LLC Series III-E 2/21/20 $28,999,922 
Outset Medical, Inc. 5/5/15 $7,180,030 
Outset Medical, Inc. Series B 5/5/15 $11,319,970 
Outset Medical, Inc. Series E 1/27/20 $1,850,000 
RPI International Holdings LP 5/21/15 - 3/23/16 $26,504,031 

Affiliated Central Funds

Information regarding fiscal year to date income earned by the Fund from investments in Fidelity Central Funds is as follows:

Fund Income earned 
Fidelity Cash Central Fund $97,099 
Fidelity Securities Lending Cash Central Fund 278,335 
Total $375,434 

Amounts in the income column in the above table include any capital gain distributions from underlying funds. Amount for Fidelity Securities Lending Cash Central Fund represents the income earned on investing cash collateral, less rebates paid to borrowers and any lending agent fees associated with the loan, plus any premium payments received for lending certain types of securities.

Investment Valuation

Investments are valued as of 4:00 p.m. Eastern time on the last calendar day of the period. Security transactions are accounted for as of trade date. The Board of Trustees (the Board) has delegated the day to day responsibility for the valuation of the Fund's investments to the Fair Value Committee (the Committee) established by the Fund's investment adviser. In accordance with valuation policies and procedures approved by the Board, the Fund attempts to obtain prices from one or more third party pricing vendors or brokers to value its investments. When current market prices, quotations or currency exchange rates are not readily available or reliable, investments will be fair valued in good faith by the Committee, in accordance with procedures adopted by the Board. Factors used in determining fair value vary by investment type and may include market or investment specific events. The frequency with which these procedures are used cannot be predicted and they may be utilized to a significant extent. The Committee oversees the Fund’s valuation policies and procedures and reports to the Board on the Committee's activities and fair value determinations. The Board monitors the appropriateness of the procedures used in valuing the Fund's investments and ratifies the fair value determinations of the Committee. The Fund categorizes the inputs to valuation techniques used to value its investments into a disclosure hierarchy consisting of three levels: Level 1 - quoted prices in active markets for identical investments: Level 2 - other significant observable inputs (including quoted prices for similar investments, interest rates, prepayment speeds etc.): Level 3 - unobservable inputs (including the Fund's own assumptions based on the best information available). Changes in valuation techniques may result in transfers in or out of an assigned level within the disclosure hierarchy. Valuation techniques used to value the Fund's investments by major category are as follows:

Equity securities, including restricted securities, for which market quotations are readily available, are valued at the last reported sale price or official closing price as reported by a third party pricing vendor on the primary market or exchange on which they are traded and are categorized as Level 1 in the hierarchy. In the event there were no sales during the day or closing prices are not available, securities are valued at the last quoted bid price or may be valued using the last available price and are generally categorized as Level 2 in the hierarchy. For foreign equity securities, when market or security specific events arise, comparisons to the valuation of American Depositary Receipts (ADRs), futures contracts, Exchange-Traded Funds (ETFs) and certain indexes as well as quoted prices for similar securities may be used and would be categorized as Level 2 in the hierarchy. For equity securities, including restricted securities, where observable inputs are limited, assumptions about market activity and risk are used and these securities may be categorized as Level 3 in the hierarchy.  Securities, including private placements or other restricted securities, for which observable inputs are not available are valued using alternate valuation approaches, including the market approach, the income approach and cost approach are categorized as Level 3 in the hierarchy. The market approach considers factors including the price of recent investments in the same or a similar security or financial metrics of comparable securities. The income approach considers factors including expected future cash flows, security specific risks and corresponding discount rates. The cost approach considers factors including the value of the security’s underlying assets and liabilities. 

Investments in open-end mutual funds, including the Fidelity Central Funds, are valued at their closing net asset value each business day and are categorized as Level 1 in the hierarchy.

For additional information on the Fund's significant accounting policies, please refer to the Fund's most recent semiannual or annual shareholder report.





The fund's schedule of investments as of the date on the cover of this report has not been audited. This report is provided for the general information of the fund's shareholders. For more information regarding the fund and its holdings, please see the fund's most recent prospectus and annual report.

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