0001752724-20-010838.txt : 20200124 0001752724-20-010838.hdr.sgml : 20200124 20200124142209 ACCESSION NUMBER: 0001752724-20-010838 CONFORMED SUBMISSION TYPE: NPORT-P PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20191130 FILED AS OF DATE: 20200124 PERIOD START: 20200228 FILER: COMPANY DATA: COMPANY CONFORMED NAME: FIDELITY SELECT PORTFOLIOS CENTRAL INDEX KEY: 0000320351 IRS NUMBER: 000000000 STATE OF INCORPORATION: MA FISCAL YEAR END: 0228 FILING VALUES: FORM TYPE: NPORT-P SEC ACT: 1940 Act SEC FILE NUMBER: 811-03114 FILM NUMBER: 20544929 BUSINESS ADDRESS: STREET 1: 245 SUMMER STREET CITY: BOSTON STATE: MA ZIP: 02210 BUSINESS PHONE: 617-563-7000 MAIL ADDRESS: STREET 1: 245 SUMMER STREET CITY: BOSTON STATE: MA ZIP: 02210 0000320351 S000007466 Health Care Portfolio C000020440 Health Care Portfolio FSPHX NPORT-P 1 primary_doc.xml NPORT-P false 0000320351 XXXXXXXX S000007466 C000020440 FIDELITY SELECT PORTFOLIOS 811-03114 0000320351 Z57125JG1LHEQKDYS630 245 Summer Street Boston 02210 1-800-FIDELITY Select Health Care Portfolio S000007466 I3SBCDEPIC5NBQILUV22 2020-02-28 2019-11-30 N 7609231383.06 125884134.5 7483347248.56 0 0 0 0 0 0 0 0 0 0 0 0 0 9902599.51 N RPI INTERNATIONAL HOLDINGS LP N/A RPI INTERNATIONAL HOLDINGS LP P/P N/A 199753.00000000 NS USD 31158471.71000000 0.416370785359 Long EC CORP KY Y 3 N N N BRISTOL-MYERS SQUIBB CO HLYYNH7UQUORYSJQCN42 BRISTOL-MYERS SQUIBB CO 110122108 1000000.00000000 NS USD 56940000.00000000 0.760889453726 Long EC CORP US N 1 N N N NATERA INC N/A NATERA INC 632307104 400000.00000000 NS USD 14596000.00000000 0.195046407913 Long EC CORP US N 1 N N N VERTEX PHARMACEUTICALS INC 54930015RAQRRZ5ZGJ91 VERTEX PHARMACEUTICALS INC 92532F100 1690000.00000000 NS USD 374757500.00000000 5.007886010797 Long EC CORP US N 1 N N N MORPHOSYS AG 529900493806K77LRE72 MORPHOSYS AG N/A 200000.00000000 NS 24724391.89000000 0.330392150314 Long EC CORP DE N 1 N N N SAGE THERAPEUTICS INC 5493000JX4BJS9W6CN35 SAGE THERAPEUTICS INC 78667J108 86679.00000000 NS USD 13415308.83000000 0.179268826962 Long EC CORP US N 1 N N N MASIMO CORP 549300Q4A8JK0PIYCU29 MASIMO CORP 574795100 600000.00000000 NS USD 93042000.00000000 1.243320627916 Long EC CORP US N 1 N N N VIELA BIO INC N/A VIELA BIO INC 926613100 566900.00000000 NS USD 17551224.00000000 0.234537078355 Long EC CORP US N 1 N N N NEUROCRINE BIOSCIENCES INC 549300FECER0XBN49756 NEUROCRINE BIOSCIENCES INC 64125C109 600000.00000000 NS USD 69966000.00000000 0.934955945195 Long EC CORP US N 1 N N N GRITSTONE ONCOLOGY INC 5493003TER6KY3MUVY84 GRITSTONE ONCOLOGY INC 39868T105 584900.00000000 NS USD 5094479.00000000 0.068077543788 Long EC CORP US N 1 N N N BEIGENE LTD 549300JFUK6FRD5MH739 BEIGENE LTD SP ADR 07725L102 260000.00000000 NS USD 52855400.00000000 0.706306927159 Long EC CORP KY N 1 N N N ATRICURE INC N/A ATRICURE INC 04963C209 1500000.00000000 NS USD 44625000.00000000 0.596324058175 Long EC CORP US N 1 N N N ASCENDIS PHARMA A/S 549300B66JN3W3J8GH73 ASCENDIS PHARMA AS SPON ADR 04351P101 850308.00000000 NS USD 97938475.44000000 1.308752249320 Long EC CORP DK N 1 N N N ALNYLAM PHARMACEUTICALS INC 529900S3ZI14OWRJII50 ALNYLAM PHARMACEUTICALS INC 02043Q107 662159.00000000 NS USD 77565305.26000000 1.036505492577 Long EC CORP US N 1 N N N ZYMEWORKS INC 894500AHOYAGYLYZJL67 ZYMEWORKS INC 98985W102 782425.00000000 NS USD 34105905.75000000 0.455757358534 Long EC CORP CA N 1 N N N ROCHE HOLDING LTD 549300U41AUUVOAAOB37 ROCHE HOLDINGS AG (GENUSSCHEINE) N/A 1400000.00000000 NS 431610166.91000000 5.767608432083 Long EC CORP CH N 2 N N N KURA ONCOLOGY INC 5493005QORQTZCZYOP39 KURA ONCOLOGY INC 50127T109 1000000.00000000 NS USD 15940000.00000000 0.213006285430 Long EC CORP US N 1 N N N INTUITIVE SURGICAL INC N/A INTUITIVE SURGICAL INC 46120E602 440000.00000000 NS USD 260876000.00000000 3.486087058838 Long EC CORP US N 1 N N N HARMONY BIOSCIENCES II INC N/A HARMONY BIOSCIENCES II INC SER A PC PP N/A 10935215.00000000 NS USD 21433021.40000000 0.286409552946 Long EP CORP US Y 3 N N N INTERCEPT PHARMACEUTICALS INC N/A INTERCEPT PHARMACEUTICALS INC 45845P108 340600.00000000 NS USD 36910822.00000000 0.493239465896 Long EC CORP US N 1 N N N UNIQURE N.V. N/A UNIQURE N.V. N/A 360000.00000000 NS USD 20037600.00000000 0.267762531049 Long EC CORP NL N 1 N N N ZOGENIX INC 54930089H3HF4C32SK78 ZOGENIX INC 98978L204 884600.00000000 NS USD 42266188.00000000 0.564803243737 Long EC CORP US N 1 N N N VIKING THERAPEUTICS INC 529900IVC72YPFA25M37 VIKING THERAPEUTICS INC 92686J106 1160000.00000000 NS USD 8491200.00000000 0.113467940454 Long EC CORP US N 1 N N ARGENX SE 7245009C5FZE6G9ODQ71 ARGENX SE SPONSORED ADR 04016X101 595900.00000000 NS USD 88222995.00000000 1.178924244320 Long EC CORP NL N 1 N N N IMMUNOMEDICS INC 5493007ZU7DDO8PSIM59 IMMUNOMEDICS INC 452907108 900000.00000000 NS USD 16902000.00000000 0.225861495378 Long EC CORP US N 1 N N HOLOGIC INC 549300DYP6F5ZJL0LB74 HOLOGIC INC 436440101 1690000.00000000 NS USD 86730800.00000000 1.158984036410 Long EC CORP US N 1 N N N CARRIAGE SERVICES INC N/A CARRIAGE SERVICES INC 143905107 600000.00000000 NS USD 14430000.00000000 0.192828149231 Long EC CORP US N 1 N N N CASTLIGHT HEALTH INC 549300K52FAO83JL0L06 CASTLIGHT HEALTH INC 14862Q100 3850000.00000000 NS USD 5351500.00000000 0.071512116466 Long EC CORP US N 1 N N N ABBVIE INC FR5LCKFTG8054YNNRU85 ABBVIE INC 00287Y109 1000000.00000000 NS USD 87730000.00000000 1.172336350112 Long EC CORP US N 1 N N N CASTLIGHT HEALTH INC 549300K52FAO83JL0L06 CASTLIGHT HEALTH INC A (UNLISTED) N/A 1845550.00000000 NS USD 2565314.50000000 0.034280308193 Long EC CORP US N 1 N N N ALLAKOS INC 549300S6ZD1W6BPMDY37 ALLAKOS INC 01671P100 330000.00000000 NS USD 31350000.00000000 0.418930178684 Long EC CORP US N 1 N N INSMED INC 529900Q55QAG41CCAC11 INSMED INC 457669307 1240000.00000000 NS USD 28582000.00000000 0.381941383322 Long EC CORP US N 1 N N N INSULET CORP 549300TZTYD2PYN92D43 INSULET CORP 45784P101 1000000.00000000 NS USD 185700000.00000000 2.481509862257 Long EC CORP US N 1 N N N GENMARK DIAGNOSTICS INC N/A GENMARK DIAGNOSTICS INC 372309104 2470000.00000000 NS USD 13782600.00000000 0.184176940374 Long EC CORP US N 1 N N N PREMIER INC N/A PREMIER INC 74051N102 600000.00000000 NS USD 21324000.00000000 0.284952699530 Long EC CORP US N 1 N N N BECTON DICKINSON and CO ICE2EP6D98PQUILVRZ91 BECTON DICKINSON and CO 075887109 1440000.00000000 NS USD 372240000.00000000 4.974244647963 Long EC CORP US N 1 N N N DANAHER CORP S4BKK9OTCEWQ3YHPFM11 DANAHER CORP 235851102 760000.00000000 NS USD 110944800.00000000 1.482555817803 Long EC CORP US N 1 N N N BOSTON SCIENTIFIC CORP Y6ZDD9FP4P8JSSJMW954 BOSTON SCIENTIFIC CORP 101137107 11500000.00000000 NS USD 497375000.00000000 6.646424166614 Long EC CORP US N 1 N N N OUTSET MEDICAL INC N/A OUTSET MEDICAL INC SER B PC PP N/A 8159125.00000000 NS USD 15910293.75000000 0.212609320689 Long EP CORP US Y 3 N N N XENCOR INC 549300V5IF65437JKG30 XENCOR INC 98401F105 1200000.00000000 NS USD 47280000.00000000 0.631802834073 Long EC CORP US N 1 N N N LILLY (ELI) and CO FRDRIPF3EKNDJ2CQJL29 LILLY (ELI) and CO 532457108 2160000.00000000 NS USD 253476000.00000000 3.387200828463 Long EC CORP US N 1 N N N SCHOLAR ROCK HOLDING CORP 549300Z1FLPGL4OWJ459 SCHOLAR ROCK HOLDING CORP 80706P103 94535.00000000 NS USD 804492.85000000 0.010750441256 Long EC CORP US N 1 N N N BRUKER CORP LEBZ6VLQ6I8XB1NHVY15 BRUKER CORP 116794108 1000000.00000000 NS USD 51190000.00000000 0.684052180123 Long EC CORP US N 1 N N N MORPHOSYS AG 529900493806K77LRE72 MORPHOSYS AG SPONSORED ADR 617760202 99.00000000 NS USD 3031.38000000 0.000040508343 Long EC CORP DE N 1 N N N MORPHIC HOLDING INC 549300RWWOUFLHTY1224 MORPHIC HOLDING INC 61775R105 66413.00000000 NS USD 1054638.44000000 0.014093137802 Long EC CORP US N 1 N N N G1 THERAPEUTICS INC 529900TC35UPZQYRKW13 G1 THERAPEUTICS INC 3621LQ109 917300.00000000 NS USD 19813680.00000000 0.264770287170 Long EC CORP US N 1 N N N STRYKER CORP 5493002F0SC4JTBU5137 STRYKER CORP 863667101 1000000.00000000 NS USD 204860000.00000000 2.737545020905 Long EC CORP US N 1 N N N UNITEDHEALTH GROUP INC 549300GHBMY8T5GXDE41 UNITEDHEALTH GROUP INC 91324P102 2120000.00000000 NS USD 593324400.00000000 7.928596392666 Long EC CORP US N 1 N N N MOLINA HEALTHCARE INC 549300NQQCEQ46YHZ591 MOLINA HEALTHCARE INC 60855R100 560000.00000000 NS USD 75880000.00000000 1.013984751470 Long EC CORP US N 1 N N N NOTRE DAME INTERMEDICA PARTICIPACOES SA N/A NOTRE DAME INTERMEDICA PARTICIPACOES SA N/A 2400000.00000000 NS 31989040.32000000 0.427469677104 Long EC CORP BR N 1 N N N HCA HEALTHCARE INC 529900PH4ZGUH2MNEU89 HCA HEALTHCARE INC 40412C101 1160000.00000000 NS USD 160845600.00000000 2.149380413035 Long EC CORP US N 1 N N N ACCELERON PHARMA INC 529900TQRID2UY164805 ACCELERON PHARMA INC 00434H108 650000.00000000 NS USD 31824000.00000000 0.425264242630 Long EC CORP US N 1 N N N MYOKARDIA INC 549300OLNNNZ1NI9UY54 MYOKARDIA INC 62857M105 540521.00000000 NS USD 35214943.15000000 0.470577429863 Long EC CORP US N 1 N N N BLUEBIRD BIO INC N/A BLUEBIRD BIO INC 09609G100 535000.00000000 NS USD 43302900.00000000 0.578656830448 Long EC CORP US N 1 N N FIDELITY REVERE STREET TRUST 549300BDV45LJNXBZC55 Fidelity Cash Central Fund 31635A105 28101499.60100000 NS USD 28107119.90000000 0.375595558597 Long STIV RF US N 1 N N N CENTENE CORP DEL 549300Z7JJ4TQSQGT333 CENTENE CORP 15135B101 3700000.00000000 NS USD 223739000.00000000 2.989825175399 Long EC CORP US N 1 N N N THERAVANCE BIOPHARMA INC 5493007VTSXP4Z6MIW52 THERAVANCE BIOPHARMA INC N/A 1275435.00000000 NS USD 27753465.60000000 0.370869674734 Long EC CORP KY N 1 N N N PRINCIPIA BIOPHARMA INC 549300WHPKRLU16IRE69 PRINCIPIA BIOPHARMA INC 74257L108 770145.00000000 NS USD 27594295.35000000 0.368742682030 Long EC CORP US N 1 N N N AMGEN INC 62QBXGPJ34PQ72Z12S66 AMGEN INC 031162100 700000.00000000 NS USD 164304000.00000000 2.195595026431 Long EC CORP US N 1 N N N PENUMBRA INC 549300RGE06P3ECANU72 PENUMBRA INC 70975L107 730900.00000000 NS USD 129310828.00000000 1.727981125356 Long EC CORP US N 1 N N SAREPTA THERAPEUTICS INC 549300IKDPIED8J8IG21 SAREPTA THERAPEUTICS INC 803607100 1240000.00000000 NS USD 139487600.00000000 1.863973371365 Long EC CORP US N 1 N N HUMANA INC 529900YLDW34GJAO4J06 HUMANA INC 444859102 760000.00000000 NS USD 259334800.00000000 3.465491996912 Long EC CORP US N 1 N N N CELLECTIS SA 5493000KKX5VQ37Q2W83 CELLECTIS SA SPON ADR 15117K103 690000.00000000 NS USD 9591000.00000000 0.128164572368 Long EC CORP FR N 1 N N N INNOVENT BIOLGICS INC 25490058ONL9SCIE1R22 INNOVENT BIOLOGICS INC N/A 4000000.00000000 NS 14000664.27000000 0.187090934109 Long EC CORP KY N 1 N N N TURNING POINT THERAPEUTICS INC N/A TURNING POINT THERAPEUTICS INC 90041T108 139882.00000000 NS USD 7864166.04000000 0.105088883073 Long EC CORP US N 1 N N N APREA THERAPEUTICS INC N/A APREA THERAPEUTICS INC 03836J102 400000.00000000 NS USD 10072000.00000000 0.134592177343 Long EC CORP US N 1 N N N 10X GENOMICS INC 5493003Z6741WNLG7H43 10X GENOMICS INC CL B (180 DAY LOCKUP) N/A 3018778.00000000 NS USD 176299653.98000000 2.355892999806 Long EC CORP US N 2 N N N MOMENTA PHARMACEUTICALS INC 529900BB2VMRCT4YQ588 MOMENTA PHARMACEUTICALS INC 60877T100 500000.00000000 NS USD 8400000.00000000 0.112249234480 Long EC CORP US N 1 N N N LONZA GROUP AG 549300EFW4H2TCZ71055 LONZA GROUP AG N/A 170000.00000000 NS 57746436.61000000 0.771665869455 Long EC CORP CH N 1 N N N ALEXION PHARMACEUTICALS INC M1YXUUZR0EIMU8T0EM75 ALEXION PHARMACEUTICALS INC 015351109 1000000.00000000 NS USD 113940000.00000000 1.522580687698 Long EC CORP US N 1 N N N ASTRAZENECA PLC PY6ZZQWO2IZFZC3IOL08 ASTRAZENECA PLC N/A 3850000.00000000 NS 371940076.04000000 4.970236762854 Long EC CORP GB N 2 N N N ALLOGENE THERAPEUTICS INC N/A ALLOGENE THERAPEUTICS INC 019770106 280000.00000000 NS USD 7890400.00000000 0.105439447588 Long EC CORP US N 1 N N SHOCKWAVE MEDICAL INC 549300LDXO56IC5Y1538 SHOCKWAVE MEDICAL INC 82489T104 610000.00000000 NS USD 23887600.00000000 0.319210096853 Long EC CORP US N 1 N N CIGNA CORP 549300VIWYMSIGT1U456 CIGNA CORP 125523100 1600000.00000000 NS USD 319872000.00000000 4.274450849004 Long EC CORP US N 1 N N N DECHRA PHARMACEUTICALS PLC 213800J4UVB5OWG8VX82 DECHRA PHARMACEUTICALS PLC N/A 1280000.00000000 NS 46914716.43000000 0.626921548228 Long EC CORP GB N 1 N N N BENEFITFOCUS INC 254900W89KP1OS3RXO89 BENEFITFOCUS INC 08180D106 1000000.00000000 NS USD 23980000.00000000 0.320444838432 Long EC CORP US N 1 N N BELLUS HEALTH INC NEW 549300QZYQDSMOXCP667 BELLUS HEALTH INC 07987C204 1131700.00000000 NS USD 7921900.00000000 0.105860382217 Long EC CORP CA N 1 N N N BLUEPRINT MEDICINES CORP 5299004CC60O9T5HVM83 BLUEPRINT MEDICINES CORP 09627Y109 900000.00000000 NS USD 73836000.00000000 0.986670771080 Long EC CORP US N 1 N N N EBOS GROUP LTD N/A EBOS GROUP LTD N/A 2280000.00000000 NS 33359090.37000000 0.445777661546 Long EC CORP NZ N 1 N N N HEALTH CATALYST INC N/A HEALTH CATALYST INC 42225T107 170000.00000000 NS USD 6754100.00000000 0.090255066024 Long EC CORP US N 1 N N RECORDATI SPA 815600FBF92FD3531704 RECORDATI SPA N/A 600000.00000000 NS 25167315.49000000 0.336310940199 Long EC CORP IT N 1 N N N FIDELITY REVERE STREET TRUST 549300BDV45LJNXBZC55 Fidelity Securities Lending Cash Central Fund 31635A303 111017956.49500000 NS USD 111029058.29000000 1.483681761679 Long STIV RF US N 1 N N NEKTAR THERAPEUTICS 5299005I24806IOIYE03 NEKTAR THERAPEUTICS 640268108 1200000.00000000 NS USD 24348000.00000000 0.325362423943 Long EC CORP US N 1 N N BIONTECH AG N/A BIONTECH SE (180 DAY LOCKUP) N/A 1638432.00000000 NS USD 32411461.82000000 0.433114497342 Long EC CORP DE N 2 N N N HARMONY BIOSCIENCES II INC N/A HARMONY BIOSCIENCES II INC SER C PC PP N/A 1845926.00000000 NS USD 3618014.96000000 0.048347548761 Long EP CORP US Y 3 N N N FIBROGEN INC 549300Q914ULWWY95822 FIBROGEN INC 31572Q808 1000000.00000000 NS USD 42370000.00000000 0.566190483919 Long EC CORP US N 1 N N N 1LIFE HEALTHCARE INC N/A 1LIFE HEALTHCARE INC PC G PP N/A 1639892.00000000 NS USD 24172008.08000000 0.323010643193 Long EP CORP US Y 3 N N N GENERATION BIO N/A GENERATION BIO CO SER B PC PP N/A 130800.00000000 NS USD 1188972.00000000 0.015888237716 Long EP CORP US Y 3 N N N HEALTHEQUITY INC 529900LRJU1RAFQHM467 HEALTHEQUITY INC 42226A107 600000.00000000 NS USD 37734000.00000000 0.504239596889 Long EC CORP US N 1 N N N 2019-12-30 Stacie M. Smith Stacie M. Smith Stacie M. Smith President and Treasurer XXXX NPORT-EX 2 QTLY_63_20191130.htm

Quarterly Holdings Report
for

Fidelity® Select Portfolio®

Health Care Portfolio

November 30, 2019







HEA-QTLY-0120
1.810696.115





Schedule of Investments November 30, 2019 (Unaudited)

Showing Percentage of Net Assets

Common Stocks - 98.7%   
 Shares Value 
Biotechnology - 25.7%   
Biotechnology - 25.7%   
AbbVie, Inc. 1,000,000 $87,730,000 
Acceleron Pharma, Inc. (a) 650,000 31,824,000 
Alexion Pharmaceuticals, Inc. (a) 1,000,000 113,940,000 
Allakos, Inc. (a)(b) 330,000 31,350,000 
Allogene Therapeutics, Inc. (a)(b) 280,000 7,890,400 
Alnylam Pharmaceuticals, Inc. (a) 664,659 77,858,155 
Amgen, Inc. 700,000 164,304,000 
Aprea Therapeutics, Inc. 400,000 10,072,000 
Argenx SE ADR (a) 595,900 88,222,995 
Ascendis Pharma A/S sponsored ADR (a) 850,308 97,938,475 
BeiGene Ltd. ADR (a) 260,000 52,855,400 
BELLUS Health, Inc. (a) 1,131,700 7,921,900 
BioNTech AG 1,638,432 32,411,462 
bluebird bio, Inc. (a)(b) 535,000 43,302,900 
Blueprint Medicines Corp. (a) 900,000 73,836,000 
Cellectis SA sponsored ADR (a) 690,000 9,591,000 
FibroGen, Inc. (a) 1,000,000 42,370,000 
G1 Therapeutics, Inc. (a) 917,300 19,813,680 
Gritstone Oncology, Inc. (a) 584,900 5,094,479 
Immunomedics, Inc. (a)(b) 900,000 16,902,000 
Innovent Biolgics, Inc. (a)(c) 4,000,000 14,000,664 
Insmed, Inc. (a) 1,240,000 28,582,000 
Intercept Pharmaceuticals, Inc. (a) 340,600 36,910,822 
Kura Oncology, Inc. (a) 1,000,000 15,940,000 
Momenta Pharmaceuticals, Inc. (a) 500,000 8,400,000 
Morphic Holding, Inc. 66,413 1,054,638 
Morphosys AG (a) 200,000 24,724,392 
Morphosys AG sponsored ADR (a) 99 3,031 
Natera, Inc. (a) 400,000 14,596,000 
Neurocrine Biosciences, Inc. (a) 600,000 69,966,000 
Principia Biopharma, Inc. (a) 770,145 27,594,295 
Sage Therapeutics, Inc. (a) 86,679 13,415,309 
Sarepta Therapeutics, Inc. (a)(b) 1,240,000 139,487,600 
Scholar Rock Holding Corp. (a) 94,535 804,493 
Turning Point Therapeutics, Inc. 147,182 8,274,572 
uniQure B.V. (a) 360,000 20,037,600 
Vertex Pharmaceuticals, Inc. (a) 1,690,000 374,757,500 
Viela Bio, Inc. 600,000 18,576,000 
Viking Therapeutics, Inc. (a)(b) 1,160,000 8,491,200 
Xencor, Inc. (a) 1,200,000 47,280,000 
Zymeworks, Inc. (a) 782,425 34,105,906 
  1,922,230,868 
Diversified Consumer Services - 0.2%   
Specialized Consumer Services - 0.2%   
Carriage Services, Inc. 600,000 14,430,000 
Health Care Equipment & Supplies - 27.0%   
Health Care Equipment - 27.0%   
Atricure, Inc. (a) 1,500,000 44,625,000 
Becton, Dickinson & Co. 1,440,000 372,240,000 
Boston Scientific Corp. (a) 11,500,000 497,375,000 
Danaher Corp. 760,000 110,944,800 
Genmark Diagnostics, Inc. (a) 2,470,000 13,782,600 
Hologic, Inc. (a) 1,690,000 86,730,800 
Insulet Corp.(a) 1,000,000 185,700,000 
Intuitive Surgical, Inc. (a) 440,000 260,876,000 
Masimo Corp. (a) 600,000 93,042,000 
Penumbra, Inc. (a)(b) 730,900 129,310,828 
Shockwave Medical, Inc. (a)(b) 610,000 23,887,600 
Stryker Corp. 1,000,000 204,860,000 
  2,023,374,628 
Health Care Providers & Services - 23.5%   
Health Care Distributors & Services - 0.4%   
EBOS Group Ltd. 2,280,000 33,359,090 
Health Care Facilities - 2.2%   
HCA Holdings, Inc. 1,160,000 160,845,600 
Health Care Services - 4.6%   
Cigna Corp. 1,600,000 319,872,000 
Premier, Inc. (a) 600,000 21,324,000 
  341,196,000 
Managed Health Care - 16.3%   
Centene Corp. (a) 3,700,000 223,739,000 
HealthEquity, Inc. (a) 600,000 37,734,000 
Humana, Inc. 760,000 259,334,800 
Molina Healthcare, Inc. (a) 560,000 75,880,000 
Notre Dame Intermedica Participacoes SA 2,400,000 31,989,040 
UnitedHealth Group, Inc. 2,120,000 593,324,401 
  1,222,001,241 
TOTAL HEALTH CARE PROVIDERS & SERVICES  1,757,401,931 
Health Care Technology - 0.2%   
Health Care Technology - 0.2%   
Castlight Health, Inc. (a) 1,845,550 2,565,315 
Castlight Health, Inc. Class B (a) 3,850,000 5,351,500 
Health Catalyst, Inc. (b) 170,000 6,754,100 
  14,670,915 
Life Sciences Tools & Services - 3.8%   
Life Sciences Tools & Services - 3.8%   
10X Genomics, Inc. 3,018,778 176,299,654 
Bruker Corp. 1,000,000 51,190,000 
Lonza Group AG 170,000 57,746,437 
  285,236,091 
Pharmaceuticals - 18.0%   
Pharmaceuticals - 18.0%   
AstraZeneca PLC (United Kingdom) 3,850,000 371,940,076 
Bristol-Myers Squibb Co. 1,000,000 56,940,000 
Dechra Pharmaceuticals PLC 1,280,000 46,914,716 
Eli Lilly & Co. 2,160,000 253,476,000 
MyoKardia, Inc. (a) 540,521 35,214,943 
Nektar Therapeutics (a)(b) 1,200,000 24,348,000 
Recordati SpA 600,000 25,167,315 
Roche Holding AG (participation certificate) 1,400,000 431,610,167 
RPI International Holdings LP (a)(d)(e) 199,753 31,158,472 
Theravance Biopharma, Inc. (a) 1,275,435 27,753,466 
Zogenix, Inc. (a) 884,600 42,266,188 
  1,346,789,343 
Software - 0.3%   
Application Software - 0.3%   
Benefitfocus, Inc. (a)(b) 997,312 23,915,542 
TOTAL COMMON STOCKS   
(Cost $4,720,899,231)  7,388,049,318 
Convertible Preferred Stocks - 0.9%   
Biotechnology - 0.0%   
Biotechnology - 0.0%   
Generation Bio Series B (a)(d)(e) 130,800 1,188,972 
Health Care Providers & Services - 0.3%   
Health Care Services - 0.3%   
1Life Healthcare, Inc. Series G (a)(d)(e) 1,639,892 24,172,008 
Pharmaceuticals - 0.4%   
Pharmaceuticals - 0.4%   
Harmony Biosciences II, Inc.:   
Series A (a)(d)(e) 10,935,215 21,433,021 
Series C (d)(e) 1,845,926 3,618,015 
  25,051,036 
Software - 0.2%   
Application Software - 0.2%   
Outset Medical, Inc. Series B (a)(d)(e) 8,159,125 15,910,294 
TOTAL CONVERTIBLE PREFERRED STOCKS   
(Cost $45,049,489)  66,322,310 
Money Market Funds - 2.1%   
Fidelity Cash Central Fund 1.61% (f) 38,047,369 38,054,979 
Fidelity Securities Lending Cash Central Fund 1.61% (f)(g) 115,864,896 115,876,483 
TOTAL MONEY MARKET FUNDS   
(Cost $153,929,078)  153,931,462 
TOTAL INVESTMENT IN SECURITIES - 101.7%   
(Cost $4,919,877,798)  7,608,303,090 
NET OTHER ASSETS (LIABILITIES) - (1.7)%  (127,082,888) 
NET ASSETS - 100%  $7,481,220,202 

Legend

 (a) Non-income producing

 (b) Security or a portion of the security is on loan at period end.

 (c) Security exempt from registration under Rule 144A of the Securities Act of 1933. These securities may be resold in transactions exempt from registration, normally to qualified institutional buyers. At the end of the period, the value of these securities amounted to $14,000,664 or 0.2% of net assets.

 (d) Restricted securities - Investment in securities not registered under the Securities Act of 1933 (excluding 144A issues). At the end of the period, the value of restricted securities (excluding 144A issues) amounted to $97,480,782 or 1.3% of net assets.

 (e) Level 3 security

 (f) Affiliated fund that is generally available only to investment companies and other accounts managed by Fidelity Investments. The rate quoted is the annualized seven-day yield of the fund at period end. A complete unaudited listing of the fund's holdings as of its most recent quarter end is available upon request. In addition, each Fidelity Central Fund's financial statements are available on the SEC's website or upon request.

 (g) Investment made with cash collateral received from securities on loan.

Additional information on each restricted holding is as follows:

Security Acquisition Date Acquisition Cost 
1Life Healthcare, Inc. Series G 4/10/14 $10,800,001 
Generation Bio Series B 2/21/18 $1,196,258 
Harmony Biosciences II, Inc. Series A 9/22/17 $10,935,215 
Harmony Biosciences II, Inc. Series C 8/9/19 $3,618,015 
Outset Medical, Inc. Series B 5/5/15 $18,500,000 
RPI International Holdings LP 5/21/15 - 3/23/16 $26,504,031 

Affiliated Central Funds

Information regarding fiscal year to date income earned by the Fund from investments in Fidelity Central Funds is as follows:

Fund Income earned 
Fidelity Cash Central Fund $569,859 
Fidelity Securities Lending Cash Central Fund 762,668 
Total $1,332,527 

Amounts in the income column in the above table include any capital gain distributions from underlying funds. Amount for Fidelity Securities Lending Cash Central Fund represents the income earned on investing cash collateral, less rebates paid to borrowers and any lending agent fees associated with the loan, plus any premium payments received for lending certain types of securities.

Investment Valuation

Investments are valued as of 4:00 p.m. Eastern time on the last calendar day of the period. Security transactions are accounted for as of trade date. The Board ofTrustees (the Board) has delegated the day to day responsibility for the valuation of the Fund's investments to the Fair Value Committee (the Committee) established by the Fund's investment adviser. In accordance with valuation policies and procedures approved by the Board, the Fund attempts to obtain prices from one or more third party pricing vendors or brokers to value its investments. When current market prices, quotations or currency exchange rates are not readily available or reliable, investments will be fair valued in good faith by the Committee, in accordance with procedures adopted by the Board. Factors used in determining fair value vary by investment type and may include market or investment specific events. The frequency with which these procedures are used cannot be predicted and they may be utilized to a significant extent. The Committee oversees the Fund’s valuation policies and procedures and reports to the Board on the Committee's activities and fair value determinations. The Board monitors the appropriateness of the procedures used in valuing the Fund's investments and ratifies the fair value determinations of the Committee. The Fund categorizes the inputs to valuation techniques used to value its investments into a disclosure hierarchy consisting of three levels: Level 1 - quoted prices in active markets for identical investments: Level 2 - other significant observable inputs (including quoted prices for similar investments, interest rates, prepayment speeds etc.): Level 3 - unobservable inputs (including the Fund's own assumptions based on the best information available). Changes in valuation techniques may result in transfers in or out of an assigned level within the disclosure hierarchy. Valuation techniques used to value the Fund's investments by major category are as follows:

Equity securities, including restricted securities, for which market quotations are readily available, are valued at the last reported sale price or official closing price as reported by a third party pricing vendor on the primary market or exchange on which they are traded and are categorized as Level 1 in the hierarchy. In the event there were no sales during the day or closing prices are not available, securities are valued at the last quoted bid price or may be valued using the last available price and are generally categorized as Level 2 in the hierarchy. For foreign equity securities, when market or security specific events arise, comparisons to the valuation of American Depositary Receipts (ADRs), futures contracts, Exchange-Traded Funds (ETFs) and certain indexes as well as quoted prices for similar securities may be used and would be categorized as Level 2 in the hierarchy. For equity securities, including restricted securities, where observable inputs are limited, assumptions about market activity and risk are used and these securities may be categorized as Level 3 in the hierarchy. Securities, including private placements or other restricted securities, for which observable inputs are not available, are valued using alternate valuation approaches, including the market approach, income approach and cost approach and are categorized as Level 3 in the hierarchy. The market approach considers factors including the price of recent investments in the same or a similar security or financial metrics of comparable securities. The income approach considers factors including expected future cash flows, security specific risks and corresponding discount rates. The cost approach considers factors including the value of the security's underlying assets and liabilities.

Investments in open-end mutual funds, including the Fidelity Central Funds, are valued at their closing net asset value each business day and are categorized as Level 1 in the hierarchy.

For additional information on the Fund's significant accounting policies, please refer to the Fund's most recent semiannual or annual shareholder report.





The fund's schedule of investments as of the date on the cover of this report has not been audited. This report is provided for the general information of the fund's shareholders. For more information regarding the fund and its holdings, please see the fund's most recent prospectus and annual report.

Third party trademarks and service marks are the property of their respective owners. All other trademarks and service marks are the property of FMR LLC or an affiliate.