License Agreements (Details) - USD ($)	Dec. 31, 2022	Oct. 31, 2021	Jun. 30, 2021	Dec. 31, 2015
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Annual license maintenance fee, after first sale		$ 150,000,000
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Shares issued under license agreement				382,030
Annual license maintenance fee		20,000,000		$ 10,000,000
Annual license maintenance fee, year seven				20,000,000
Potential milestone payments		$ 23,200,000		$ 10,600,000
Royalties, net of sales		4.00%		4.00%
Sublicensing fee				$ 0.25
Annual license maintenance fee, year four		$ 30,000,000
Shares held by third party	382,030
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sublicensing fee		0.10
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sublicensing fee		0.25
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone payments			$ 1,200,000
Royalties, net of sales			1.50%
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sublicensing fee			$ 0.10
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sublicensing fee			$ 0.20
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Annual license maintenance fee		20,000,000
Potential milestone payments		$ 5,000,000
Royalties, net of sales		2.00%
Annual license maintenance fee, year four		$ 50,000,000
Annual license maintenance fee, years two and three		25,000,000
Change of control fee		300,000
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sublicensing fee		0.03
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sublicensing fee		$ 0.20