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Share-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Share-based Payment Arrangement [Abstract]  
Schedule of Share-Based Compensation Expense The following table summarizes the components of share-based compensation expense for the years ended December 31, 2021 and 2020 ($ in thousands):
Year Ended December 31,
20212020
Research and development$760 $179 
General and administrative1,245 1,086 
Total share-based compensation expense$2,005 $1,265 

Total compensation cost related to unvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at December 31, 2021 were as follows ($ in thousands):
Stock OptionsRestricted Stock UnitsRestricted Stock
Unrecognized compensation cost $757 $149 $546 
Expected weighted-average period in years of compensation cost to be recognized1.641.571.70
Schedule of Fair Value of Shares Vested and Weighted Average Estimated Fair Values of Shares Granted
Total fair value of shares vested and the weighted average estimated fair values of shares granted for the years ended December 31, 2021 and 2020 were as follows ($ in thousands):
Stock Options
Year Ended December 31,
20212020
Total fair value of shares vested$757 $536 
Weighted average estimated fair value of shares granted0.91 2.11 
Schedule of Assumptions in Calculating Fair Values of Stock Options The range of assumptions made in calculating the fair values of stock options was as follow:
Stock Options
Year Ended December 31,
20212020
Expected term - minimum (in years)66
Expected term - maximum (in years)66
Expected volatility - minimum79%75%
Expected volatility - maximum84%79%
Weighted Average volatility81%75%
Expected dividend yield
Risk-free interest rate - minimum0.63%0.40%
Risk-free interest rate - maximum1.16%1.71%