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Stockholders' Equity - Equity Issuances (Details) - USD ($)
1 Months Ended 12 Months Ended 35 Months Ended
Jul. 10, 2020
May 31, 2020
Apr. 30, 2020
Mar. 31, 2019
Aug. 31, 2018
Dec. 31, 2020
Dec. 31, 2020
Feb. 28, 2018
Lincoln Park Agreement                
Class of Stock [Line Items]                
Aggregate offering amount authorized per agreement       $ 26,000,000.0        
Commitment shares issued as consideration per agreement (shares)       181,510        
Number of shares sold (shares)       250,000        
Price of shares sold (in dollars per share)       $ 4.00        
Gross price for stock transaction       $ 1,000,000        
Term of agreement (in months)       36 months        
Number of shares allowable to direct for Regular Purchase (shares)       100,000        
Maximum obligation per directed purchase transaction for Regular Purchase       $ 2,500,000        
Maximum shares allowed in Accelerated Purchase as percent of shares in Regular Purchase (percent)       300.00%        
Maximum shares allowed in Accelerated Purchase as percent of shares traded during specified period (percent)       30.00%        
Maximum beneficial ownership allowable per agreement (percent)       9.99%        
H.C. Wainwright Sales Amended Agreement                
Class of Stock [Line Items]                
Aggregate offering amount authorized per agreement       $ 17,600,000 $ 25,000,000.0     $ 25,000,000.0
Aggregate market value of common stock held by non-affiliates       $ 52,800,000        
Maximum number of shares authorized per agreement (shares)       4,800,000        
Commission on gross proceeds due to third party (percent)         3.00%      
Stock issued (shares)           3,558,778 3,784,912  
Proceeds from issuance of stock           $ 8,500,000 $ 9,500,000  
April Purchase Agreement                
Class of Stock [Line Items]                
Number of shares sold (shares)     2,162,166          
Price of shares sold (in dollars per share)     $ 2.3125          
Number of shares called by warrants issued     1,081,083          
Proceeds from issuance of stock     $ 5,000,000.0          
Number of shares per each warrant     1          
Warrant exercise price (in dollars per share)     $ 2.2500          
Warrants expiration term     5 years 6 months          
May Purchase Agreement                
Class of Stock [Line Items]                
Number of shares sold (shares)   2,084,850            
Price of shares sold (in dollars per share)   $ 2.0625            
Number of shares called by warrants issued   1,042,425            
Proceeds from issuance of stock   $ 4,300,000            
Number of shares per each warrant   1            
Warrant exercise price (in dollars per share)   $ 2.0625            
Warrants expiration term   5 years 6 months            
July 2020 Private Placement                
Class of Stock [Line Items]                
Number of shares sold (shares) 969,694              
Price of shares sold (in dollars per share) $ 2.0625              
Number of shares called by warrants issued 484,847              
Proceeds from issuance of stock $ 2,000,000.0              
Number of shares per each warrant 1              
Warrant exercise price (in dollars per share) $ 2.0625              
Warrants expiration term 5 years 6 months