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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Cash flows from operating activities:    
Net loss $ (9,502) $ (9,062)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation 793 2,115
Depreciation and amortization 35 169
Accretion on marketable securities 133 155
Changes in operating assets and liabilities:    
Prepaid and other current assets (110) 84
Other assets 181 158
Accounts payable, accrued liabilities and other liabilities (1,735) (4,424)
Net cash used in operating activities (10,205) (12,184)
Cash flows from investing activities:    
Purchase of marketable securities (25,969) (38,321)
Sale of marketable securities 36,721 36,482
Proceeds from Sale of Furniture and Fixtures 0 2,500
Acquisition of property and equipment 0 (11)
Net cash provided by investing activities 10,752 650
Cash flows from financing activities:    
Proceeds from exercise of options 0 342
Tax withholding payments on net share settlement equity awards (130) (403)
Net proceeds from issuance of common stock 1,038 288
Repayment of notes payable 0 (136)
Net cash provided by financing activities 908 91
Net increase (decrease) in cash, cash equivalents and restricted cash 1,455 (11,443)
Cash, cash equivalents and restricted cash at beginning of period 10,299 34,168
Cash and cash equivalents at end of period 11,754 22,725
Cash paid during the period for:    
Interest 0 5
Gain (Loss) on Disposition of Assets $ 0 $ (1,379)