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Share-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2019
Share-based Compensation [Abstract]  
Schedule Share-based Compensation Expense
The following table summarizes the components of share-based compensation expense for the three months ended March 31, 2019 and 2018 (in thousands):
 
Three Months Ended March 31,
 
2019
 
2018
Research and development
$
124

 
$
41

General and administrative
423

 
106

Total share-based compensation expense
$
547

 
$
147

 
 
 
 
Schedule of Total Compensation Cost Related to Nonvested Awards
Total compensation cost related to non-vested awards not yet recognized and the weighted-average periods over which the awards were expected to be recognized at March 31, 2019 were as follows (in thousands):
 
Stock Options
 
Restricted Stock
Unrecognized compensation cost
$
934

 
$
427

Expected weighted-average period in years of compensation cost to be recognized
2.25

 
0.72

Schedule of Fair Value of Share-based Compensation Awards
Total fair value of shares vested and the weighted average estimated fair values of shares granted for the three months ended March 31, 2019 and 2018 were as follows (in thousands):
 
Stock Options
 
Three Months Ended March 31,
 
2019
 
2018
Total fair value of shares vested
$
372

 
$
82

Weighted average estimated fair value of shares granted
$
3.24

 
$
2.41