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Stockholders' Equity - Equity Issuances (Details)
1 Months Ended 12 Months Ended
Sep. 14, 2016
USD ($)
clinical_trial_subject
$ / shares
Feb. 28, 2018
USD ($)
shares
Nov. 30, 2015
USD ($)
shares
Dec. 31, 2018
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Dec. 31, 2016
shares
Aug. 31, 2018
USD ($)
shares
Class of Stock [Line Items]              
Common Stock Warrants, Shares | shares         209,818    
H.C. Wainwright Sales Agreement [Member]              
Class of Stock [Line Items]              
Stock Issued During Period, Shares, New Issues | shares       149,041      
Sale Of Stock, Aggregate Offering Amount Authorized Per Agreement   $ 12,000,000          
Sale Of Stock, Maximum Number Of Shares Authorized Per Agreement | shares   2,790,697         4,921,260
Sale Of Stock, Commission On Gross Proceeds Due To Third Party Upon, Percent   3.00%          
Proceeds from Issuance of Common Stock       $ 1,000,000      
H.C. Wainwright Sales Amended Agreement [Member]              
Class of Stock [Line Items]              
Sale Of Stock, Aggregate Offering Amount Authorized Per Agreement             $ 25,000,000
RD Purchase Agreement [Member]              
Class of Stock [Line Items]              
Shares Issued, Price Per Share | $ / shares $ 4.72            
Private Purchase Agreement [Member]              
Class of Stock [Line Items]              
Stock Issued During Period, Shares, New Issues | shares         932,204 1,400,000  
Proceeds from Issuance of Common Stock, Initial Closing $ 6,600,000            
Proceeds from Issuance of Common Stock, Second Closing         $ 4,400,000    
Number of Subjects, Phase 2 CLBS03 Clinical Trial, Second Closing | clinical_trial_subject 70            
Aspire Capital Purchase Agreement [Member]              
Class of Stock [Line Items]              
Purchase Commitment, Maximum Amount Committed, Shares | shares     1,101,928        
Purchase Commitment, Remaining Minimum Amount Committed     $ 30,000,000        
Term Of Agreement In Months     24 months        
Shares, Issued | shares         319,776    
Financial Instruments Subject to Mandatory Redemption, Settlement Terms, Fair Value of Shares         $ 1,500,000