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Stockholders' Equity - Equity Issuances (Details)
1 Months Ended 9 Months Ended 12 Months Ended
Sep. 14, 2016
USD ($)
clinical_trial_subject
$ / shares
Feb. 28, 2018
USD ($)
shares
Nov. 30, 2015
USD ($)
shares
Sep. 30, 2018
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Dec. 31, 2016
shares
Aug. 31, 2018
USD ($)
shares
Class of Stock [Line Items]              
Shares issued, price (in usd per share) | $ / shares $ 4.72            
Private Purchase Agreement [Member]              
Class of Stock [Line Items]              
Proceeds from issuance of common stock, initial closing $ 6,600,000            
Proceeds from issuance of common stock, second closing         $ 4,400,000    
Stock issued (shares) | shares         900,000 1,400,000  
Number of subjects for Phase 2 CLBS03 clinical trial, second closing | clinical_trial_subject 70            
Aspire Capital Purchase Agreement [Member]              
Class of Stock [Line Items]              
Stock issued (shares) | shares     319,776        
Proceeds from issuance of stock     $ 1,500,000        
Purchase commitment, remaining minimum amount committed     $ 30,000,000        
Purchase commitment, maximum amount committed (shares) | shares     1,100,000        
Term of agreement in months     24 months        
H.C. Wainwright Sales Agreement [Member]              
Class of Stock [Line Items]              
Stock issued (shares) | shares       149,041      
Proceeds from issuance of stock       $ 1,000,000      
Aggregate offering amount authorized per agreement   $ 12,000,000          
Maximum number of shares authorized per agreement | shares   2,790,697         4,921,260
Commission on gross proceeds due to third party (percent)   3.00%          
H.C. Wainwright Sales Amended Agreement [Member]              
Class of Stock [Line Items]              
Aggregate offering amount authorized per agreement             $ 25,000,000