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Share-Based Compensation (Tables)
 3 Months Ended
Mar. 31, 2018
Share-based Compensation [Abstract]  
Schedule Share-based Compensation Expense
The following table summarizes the components of share-based compensation expense for the three months ended March 31, 2018 and 2017 (in thousands):
 
Three Months Ended March 31,
 
2018
 
2017
Research and development
$
40

 
$
46

General and administrative
106

 
350

Discontinued operations
—

 
137

Total share-based compensation expense
$
146

 
$
533

 
 
 
 
Schedule of Total Compensation Cost Related to Nonvested Awards
Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at March 31, 2018 were as follows (in thousands):
 
Stock Options
 
Restricted Stock
Unrecognized compensation cost
$
275.1

 
$
—

Expected weighted-average period in years of compensation cost to be recognized
2.41

 
0.00
Schedule of Fair Value of Share-based Compensation Awards
Total fair value of shares vested and the weighted average estimated fair values of shares granted for the three months ended March 31, 2018 and 2017 were as follows (in thousands):
 
Stock Options
 
Three Months Ended March 31,
 
2018
 
2017
Total fair value of shares vested
$
82.4

 
$
507.1

Weighted average estimated fair value of shares granted
$
2.41

 
$
2.34