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Commitments and Contingencies (Details)
1 Months Ended 12 Months Ended
Oct. 31, 2016
patient
Dec. 31, 2017
USD ($)
patient
Dec. 31, 2016
USD ($)
Commitments and Contingencies Disclosure [Abstract]      
Number of patients enrolled | patient 19    
Number of patients still active in study | patient   92  
Operating Leases, Future Minimum Payments Due [Abstract]      
2018   $ 910,000  
2019   901,200  
2020   827,000  
2021   474,400  
2022 and thereafter   128,600  
Total minimum lease payments   3,241,200  
Operating leases expenses   $ 1,400,000 $ 1,400,000