Stockholders' Equity - Activity for Stock Options and Warrants (Details)	12 Months Ended
	Dec. 31, 2017 USD ($) $ / shares $ / warrant shares	Dec. 31, 2016 USD ($) $ / shares $ / warrant shares	Mar. 10, 2016 shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value | $	$ 100
Common stock, shares, outstanding (shares)	9,483,911	8,205,790
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value | $	$ 100	$ 0
Common Stock Warrants, Shares		388,062	141,844
Weighted Average Exercise Price, Warrants Outstanding | $ / warrant	53.2	76.5
Weighted Average Remaining Contractual Term warrant outstanding	11 months 12 days
Weighted Average Remaining Contractual Term, Warrants Outstanding		1 year 2 months 27 days
Aggregate Intrinsic Value, Warrants Outstanding | $	$ 0	$ 0
Share-based Compensation Arrangement by Share-based Payment Award, Options and Non-Option Equity Instruments, Outstanding [Roll Forward]
Warrants Granted	0
Weighted Average Exercise Price, Warrants Granted | $ / shares	$ 0
Warrants Exercised	0
Weighted Average Exercise Price, Warrants Exercised | $ / shares	$ 0
Warrants Expired	(1,937)
Weighted Average Exercise Price, Warrants Expired | $ / shares	$ 700.0
Warrants Canceled	(176,307)
Weighted Average Exercise Price, Warrants Canceled | $ / shares	$ 103.9
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value | $	$ 100
shares, vested and expected to vest	209,818
Weighted Average Exercise Price, Warrants vested & expected to vest | $ / warrant	53.20
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number	209,818
Weighted Average Exercise Price, Warrants Exercisable | $ / warrant	53.20
weighted Average Remaining Contractual Term, warrants vested	11 months 12 days
Aggregate Intrinsic Value, Warrants vested and expected to vest | $	$ 0
Aggregate Intrinsic Value, Warrants vested | $	$ 0
US Equity Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price | $ / shares	$ 33.5	$ 39.9
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term	4 years 9 months 4 days	7 years 7 months 6 days
Common stock, shares, outstanding (shares)	209,818
Weighted Average Remaining Contractual Term, Warrants Vested and Expect to Vest	11 months 12 days
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number	1,072,107
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price | $ / shares	$ 33.5
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term	4 years 9 months 4 days
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures	448,057
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares	$ 11.7
Share-based Compensation Arrangement by Share-based Payment Award, Options and Non-Option Equity Instruments, Outstanding [Roll Forward]
Stock Options, Outstanding at December 31, 2011	952,790
Stock Options Exercised	(3,835)
Stock Options Forfeited	(80,100)
Stock Options Expired	(244,413)
Stock Options, Outstanding at September 30, 2012	1,072,499	952,790
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price | $ / shares	$ 35.8
Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price | $ / shares	18.8
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price | $ / shares	$ 4.7
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number	1,063,759
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price | $ / shares	$ 32.9
Options, Vested, weighted Average Remaining Contractual Term	4 years 9 months 7 days