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Shareholders' Equity Activity for stock options and warrants (Details)
12 Months Ended
Dec. 31, 2016
USD ($)
$ / shares
$ / warrant
shares
Dec. 31, 2015
USD ($)
$ / shares
$ / warrant
shares
Mar. 10, 2016
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value | $ $ 0    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value | $ $ 0 $ 100  
Common Stock Warrants, Shares   321,404 141,844
Weighted Average Exercise Price, Warrants Outstanding | $ / warrant 76.5 137.2  
Weighted Average Remaining Contractual Term warrant outstanding 1 year 2 months 27 days    
Weighted Average Remaining Contractual Term, Warrants Outstanding   1 year 3 months 4 days  
Aggregate Intrinsic Value, Warrants Outstanding | $ $ 0 $ 0  
Share-based Compensation Arrangement by Share-based Payment Award, Options and Non-Option Equity Instruments, Outstanding [Roll Forward]      
Warrants Granted 171,845    
Weighted Average Exercise Price, Warrants Granted | $ / shares $ 9.3    
Warrants Exercised 0    
Weighted Average Exercise Price, Warrants Exercised | $ / shares $ 0    
Warrants Expired 251    
Weighted Average Exercise Price, Warrants Expired | $ / shares $ 700.0    
Warrants Canceled (105,438)    
Weighted Average Exercise Price, Warrants Canceled | $ / shares $ 152.7    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value | $ $ 0    
shares, vested and expected to vest 388,062    
Weighted Average Exercise Price, Warrants vested & expected to vest | $ / warrant 76.50    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number 388,062    
Weighted Average Exercise Price, Warrants Exercisable | $ / warrant 76.50    
weighted Average Remaining Contractual Term, warrants vested 1 year 2 months 27 days    
Aggregate Intrinsic Value, Warrants vested and expected to vest | $ $ 0    
Aggregate Intrinsic Value, Warrants vested | $ $ 0    
US Equity Plan [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price | $ / shares $ 39.9 $ 64.6  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term 7 years 7 months 6 days 6 years 10 months 17 days  
Common stock, shares, outstanding (shares) 388,062    
Weighted Average Remaining Contractual Term, Warrants Vested and Expect to Vest 1 year 2 months 27 days    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number 938,889    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price | $ / shares $ 40.3    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term 7 years 6 months 29 days    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures 464,815    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares $ 5.3    
Share-based Compensation Arrangement by Share-based Payment Award, Options and Non-Option Equity Instruments, Outstanding [Roll Forward]      
Stock Options, Outstanding at December 31, 2011 666,348    
Stock Options Exercised 0 0  
Stock Options Forfeited (107,860)    
Stock Options Expired (70,513)    
Stock Options, Outstanding at September 30, 2012 952,790 666,348  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price | $ / shares $ 48.3    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price | $ / shares 32.7    
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price | $ / shares $ 0    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number 769,224    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price | $ / shares $ 46.2    
Options, Vested, weighted Average Remaining Contractual Term 7 years 3 months 7 days