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Shareholders' Equity Components of share-based compensation expense (Details) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Oct. 06, 2014
Oct. 03, 2013
Oct. 10, 2012
Oct. 14, 2011
Jan. 18, 2011
Jun. 02, 2010
Oct. 29, 2009
May 09, 2009
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number (388,062)                  
Share-based Compensation Expense $ 2,604,400 $ 9,750,100                
Cost of Sales [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share-based Compensation Expense 333,700 545,300                
Research and Development Expense [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share-based Compensation Expense 339,100 1,811,500                
General and Administrative Expense [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share-based Compensation Expense $ 1,931,600 $ 7,393,300                
Stock Options [Member] | 2009 Equity Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Common stock, shares authorized (shares)     899,500 599,500 45,000 237,500 177,500 137,500 97,500 38,000
Stock Options [Member] | Non US Equity Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Common stock, shares authorized (shares)         57,000          
2015 Equity Plan [Member] | US Equity Plan [Member] | Stock Options [Member] | 2015 Equity Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number 0                  
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number (125,715)                  
Shares Expired 0                  
Common stock, shares authorized (shares) 440,000                  
Common Stock, Capital Shares Reserved for Future Issuance 226,932                  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number (484,010)                  
Common Stock, Shares, Outstanding 57,207                  
2009 Equity Plan [Member] | US Equity Plan [Member] | Stock Options [Member] | 2009 Equity Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number (8,093)                  
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number (156,467)                  
Shares Expired (274,784)                  
Common stock, shares authorized (shares) 899,500                  
Common Stock, Capital Shares Reserved for Future Issuance 0                  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number (460,156)                  
Common Stock, Shares, Outstanding 0                  
2003 Equity Plan [Member] | US Equity Plan [Member] | Stock Options [Member] | 2003 Equity Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number (925)                  
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number (8,922)                  
Shares Expired (5,629)                  
Common stock, shares authorized (shares) 25,000                  
Common Stock, Capital Shares Reserved for Future Issuance 0                  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number (9,524)                  
Common Stock, Shares, Outstanding 0