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Shareholders' Equity (Tables)
 12 Months Ended
Dec. 31, 2016
Shareholders’ Equity [Abstract]  
Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan
The number of remaining shares authorized to be issued under the various equity plans are as follows as of December 31, 2016:
 
 2003 Equity Plan
 
 2009 Equity Plan
 
 2015 Equity Plan
Shares Authorized for Issuance
25,000

 
899,500

 
440,000

Evergreen increase of shares
—

 
—

 
226,932

Outstanding Stock Options
(9,524
)
 
(460,156
)
 
(484,010
)
Exercised Stock Options
(925
)
 
(8,093
)
 
—

Restricted stock or equity grants issued under Equity Plans
(8,922
)
 
(156,467
)
 
(125,715
)
Shares Expired
(5,629
)
 
(274,784
)
 
—

Total common shares remaining to be issued under the Equity Plans
—

 
—

 
57,207
Schedule of Share-based Compensation, Stock Options, Activity
The following table summarizes the activity for stock options and warrants for the year ended December 31, 2016, as adjusted for the Reverse Stock Split:
 
Stock Options
 
Warrants
 
Shares
 
Weighted Average Exercise Price
 
Weighted Average Remaining Contractual Term (Years)
 
Aggregate Intrinsic Value (In Thousands)
 
Shares
 
Weighted Average Exercise Price
 
Weighted Average Remaining Contractual Term (Years)
 
Aggregate Intrinsic Value (In Thousands)
Outstanding at December 31, 2015
666,348

 
$
64.60

 
6.88
 
$
0.1

 
321,404

 
$
137.20

 
1.26
 
$
—

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Changes during the Year:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Granted
464,815

 
$
5.30

 
 
 
 
 
171,845

 
$
9.30

 
 
 
 
Exercised
—

 
$
—

 
 
 
 
 
—

 
$
—

 
 
 
 
Forfeited
(70,513
)
 
$
32.70

 
 
 
 
 
251

 
$
700.00

 
 
 
 
Expired
(107,860
)
 
$
48.30

 
 
 
 
 
(105,438
)
 
$
152.70

 
 
 
 
Outstanding at December 31, 2016
952,790

 
$
39.90

 
7.60
 
$
—

 
388,062

 
$
76.50

 
1.24
 
$
—

Vested at December 31, 2016 or expected to vest in the future
938,889

 
$
40.3

 
7.58
 
$
—

 
388,062

 
$
76.50

 
1.24
 
$
—

Exercisable at December 31, 2016
769,224

 
$
46.2

 
7.27
 
$
—

 
388,062

 
$
76.50

 
1.24
 
$
—

The following table summarizes the components of share-based compensation expense for the years ended December 31, 2016 and 2015 ($ in thousands):
 
Year Ended December 31,
 
2016
 
2015
Cost of revenues
$
333.7

 
$
545.3

Research and development
339.1

 
1,811.5

Selling, general and administrative
1,931.6

 
7,393.3

Total share-based compensation expense
$
2,604.4

 
$
9,750.1
Restricted Stock
During the years ended December 31, 2016 and 2015, the Company issued restricted stock for services as follows ($ in thousands, except share data):
 
 
 
 
 
2016
 
2015
 
Number of Restricted Stock Issued
 
126,849

 
92,800

 
Value of Restricted Stock Issued
 
$
698.1

 
$
2,488.6