Shareholders' Equity - Stock options and warrants (Details)	6 Months Ended	12 Months Ended
	Jun. 30, 2016 USD ($) $ / shares $ / warrant shares	Dec. 31, 2015 USD ($) $ / shares $ / warrant shares	Mar. 10, 2016 shares
Stock Options and Warrants [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value | $	$ 200	$ 100
Common Stock Warrants, Shares	362,399	321,404	141,844
Weighted Average Exercise Price, Warrants Outstanding | $ / warrant	85.40	137.20
Weighted Average Remaining Contractual Term warrant outstanding	1 year 29 days	1 year 3 months 4 days
Aggregate Intrinsic Value, Warrants Outstanding | $	$ 0	$ 0
Warrants Granted	141,845
Warrants Canceled	(100,850)
Weighted Average Exercise Price, Warrants Granted | $ / shares	$ 10.00
Warrants Exercised	0
Weighted Average Exercise Price, Warrants Exercised | $ / shares	$ 0.00
Warrants Expired	0
Weighted Average Exercise Price, Warrants Expired | $ / shares	$ 0.00
Weighted Average Exercise Price, Warrants Canceled | $ / shares	$ 145.10
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value | $	$ 200
shares, vested and expected to vest	362,399
Weighted Average Exercise Price, Warrants vested & expected to vest | $ / warrant	85.40
Aggregate Intrinsic Value, Warrants vested and expected to vest | $	$ 0
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value | $	$ 0
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number	362,650
Weighted Average Exercise Price, Warrants Exercisable | $ / warrant	85.40
weighted Average Remaining Contractual Term, warrants vested	1 year 29 days
Aggregate Intrinsic Value, Warrants vested | $	$ 0
US Equity Plan [Member]
Stock Options and Warrants [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number	942,129	666,348.0
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price | $ / shares	$ 40.90	$ 64.60
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term	7 years 11 months 12 days	6 years 10 months 17 days
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures	448,365
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price | $ / shares	$ 5.30
Stock Options Exercised	0
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price | $ / shares	$ 0.00
Stock Options Expired	(61,983)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price | $ / shares	$ 34.20
Stock Options Forfeited	(110,601)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price | $ / shares	$ 45.90
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number	938,964
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price | $ / shares	$ 41.10
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term	7 years 11 months 5 days
Weighted Average Remaining Contractual Term, Warrants Vested and Expect to Vest	1 year 29 days
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number	761,371
Weighted average estimated fair value of shares granted | $ / shares	$ 47.30
Options, Vested, weighted Average Remaining Contractual Term	7 years 7 months 24 days