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Shareholders' Equity - Equity Issuances (Details)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 14, 2016
USD ($)
clinical_trial_subject
$ / shares
shares
Nov. 30, 2015
USD ($)
shares
Mar. 31, 2016
USD ($)
shares
Sep. 30, 2016
USD ($)
shares
Sep. 30, 2015
USD ($)
Dec. 31, 2016
USD ($)
shares
Jun. 30, 2016
shares
Mar. 10, 2016
$ / shares
shares
Dec. 31, 2015
shares
May 01, 2015
USD ($)
Class of Stock [Line Items]                    
Common Stock Warrants, Shares | shares             362,399 141,844 321,404  
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares               $ 10.00    
Share Price | $ / shares               $ 7.05    
Proceeds from Issuance of Warrants     $ 1,000,000              
Shares Issued, Price Per Share | $ / shares $ 4.72                  
Net proceeds from issuance of common stock       $ 11,650,712 $ 36,136,839          
Common Stock, Shares, Issued | shares       8,181,921         5,673,302  
RD Purchase Agreement [Member]                    
Class of Stock [Line Items]                    
Stock Issued During Period, Shares, New Issues | shares 847,458                  
Proceeds from Issuance of Common Stock $ 4,000,000                  
Private Purchase Agreement [Member]                    
Class of Stock [Line Items]                    
Stock Issued During Period, Shares, New Issues | shares       1,398,305            
Proceeds from Issuance of Common Stock       $ 6,600,000            
Purchase Commitment, Maximum Amount Committed, Shares | shares 4,449,153                  
Proceeds from Issuance of Common Stock, Initial Closing $ 12,600,000                  
Proceeds from Issuance of Common Stock, Second Closing $ 8,400,000                  
Number of Subjects, Phase 2 CLBS03 Clinical Trial, Second Closing | clinical_trial_subject 70                  
Aspire Capital Purchase Agreement [Member]                    
Class of Stock [Line Items]                    
Purchase Commitment, Maximum Amount Committed, Shares | shares   1,101,927.6                
Purchase Commitment, Remaining Minimum Amount Committed   $ 30,000,000                
Term of agreement in months   24 months                
Stock Issued During Period, Shares, Other | shares   84,269.6 5,000              
Net proceeds from issuance of common stock     $ 30,000              
Shares, Issued | shares     109,270              
Common Stock, Value, Issued     $ 300,000              
Discount Applied To Weighted Average Price   5.00%                
Aspire Capital Purchase Agreement [Member]                    
Class of Stock [Line Items]                    
Purchase Commitment, Remaining Minimum Amount Committed                   $ 30,000,000
Common Stock, Shares, Issued | shares     36,483.7              
Subsequent Event [Member] | Private Purchase Agreement [Member]                    
Class of Stock [Line Items]                    
Stock Issued During Period, Shares, New Issues | shares           1,271,186        
Proceeds from Issuance of Common Stock           $ 6,000,000