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Share-Based Compensation Share-Based Compensation (Details) - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Allocated Share-based Compensation Expense $ 9,750,100 $ 11,209,500 $ 6,838,700
Cost of Sales [Member]      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Allocated Share-based Compensation Expense 545,300 494,200 314,000
Research and Development Expense [Member]      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Allocated Share-based Compensation Expense 1,811,500 2,058,200 822,200
General and Administrative Expense [Member]      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Allocated Share-based Compensation Expense 7,393,300 8,657,100 5,702,500
Warrant [Member]      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Adjustments to Additional Paid in Capital, Share-based Compensation, Stock Options, Requisite Service Period Recognition $ 0 $ 9,600 $ 129,000
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum 0.00% 66.00% 73.00%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum 0.00% 66.00% 79.00%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate 0.00% 0.00% 0.00%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum 0.00% 0.79% 0.32%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum 0.00% 0.79% 1.73%
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price $ 0.00 $ 0.00 $ 3.71
Stock Options [Member]      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price $ 1.95 $ 4.56 $ 4.29
Stock Option [Member]      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Adjustments to Additional Paid in Capital, Share-based Compensation, Stock Options, Requisite Service Period Recognition $ 6,133,000 $ 5,387,100 $ 3,375,700
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum 71.00% 62.00% 61.00%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum 75.00% 77.00% 79.00%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate 0.00% 0.00% 0.00%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum 1.19% 0.12% 0.13%
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum 2.14% 3.00% 2.67%