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Fair Value Measurements Financial instruments with significant Level 3 inputs (Details) - USD ($)
6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Mar. 31, 2015
Dec. 31, 2014
May. 08, 2014
Oct. 31, 2011
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]            
Available-for-sale Securities $ 3,011,700     $ 7,080,000    
Percentage of Net Sales           10.00%
Percentage of license cost           30.00%
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]            
Acquisition-related contingent consideration 13,460,000     18,260,000 $ 11,900,000  
Accrued Liabilities and Other Liabilities 13,460,000     18,260,000    
Change in acquisition-related contingent consideration (4,800,000) $ 400,000        
Fair Value, Option, Changes in Fair Value, Gain (Loss) (4,800,000)          
Contingent Consideration Classified as Equity [Member]            
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]            
Acquisition-related contingent consideration 13,460,000     18,260,000    
Change in acquisition-related contingent consideration (4,800,000)          
Fair Value, Inputs, Level 1 [Member]            
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]            
Available-for-sale Securities 0     0    
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]            
Accrued Liabilities and Other Liabilities 0     0    
Contingent Consideration Classified as Equity, Fair Value Disclosure 0     0    
Fair Value, Inputs, Level 2 [Member]            
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]            
Available-for-sale Securities 3,011,700     7,080,000    
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]            
Accrued Liabilities and Other Liabilities 0     0    
Contingent Consideration Classified as Equity, Fair Value Disclosure 0     0    
Fair Value, Inputs, Level 3 [Member]            
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]            
Available-for-sale Securities 0     0    
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]            
Accrued Liabilities and Other Liabilities 13,460,000     18,260,000    
Contingent Consideration Classified as Equity, Fair Value Disclosure 13,460,000     $ 18,260,000    
Amorcyte, LLC [Member]            
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]            
Acquisition-related contingent consideration $ 0   $ 5,600,000