Share-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2015

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

The following table summarizes the components of share-based compensation expense for the three and six months ended June 30, 2015 and 2014 (in thousands):



	Three Months Ended June 30,				Six Months Ended June 30,
	2015		2014		2015		2014
Cost of goods sold	$	378.2	$	98.5	$	495.1	$	236.6
Research and development	1,104.2		371.6		1,526.9		848.4
Selling, general and administrative	2,933.9		1,289.6		6,110.1		4,568.5
Total share-based compensation expense	$	4,416.3	$	1,759.7	$	8,132.1	$	5,653.5

Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block]

Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at June 30, 2015 were as follows (in thousands):



	Stock Options		Warrants		Restricted Stock
Unrecognized compensation cost	$	4,979.6	$	1.0	$	401.2
Expected weighted-average period in years of compensation cost to be recognized	3.29		0.05		2.93

Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value [Table Text Block]

Total fair value of shares vested and the weighted average estimated fair values of shares granted for the six months ended June 30, 2015 and 2014 were as follows (in thousands):



	Stock Options				Warrants
	Six Months Ended June 30,				Six Months Ended June 30,
	2015		2014		2015		2014
Total fair value of shares vested	$	4,915.3	$	2,552.2	$	14.0	$	15.0
Weighted average estimated fair value of shares granted	$	2.17	$	4.92	$	—	$	—

Valuation Assumptions

The fair value of stock options and warrants at the date of grant was estimated using the Black-Scholes option pricing model. The expected volatility is based upon historical volatility of the Company’s stock. The expected term for the options is based upon observation of actual time elapsed between date of grant and exercise of options for all employees. The expected term for the warrants is based upon the contractual term of the warrants.