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Share-Based Compensation (Tables)
 12 Months Ended
Dec. 31, 2014
Share-based Compensation [Abstract]  
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]
The following table summarizes the activity for stock options and warrants for the years ended December 31, 2014 and December 31, 2013:
 
Stock Options
 
Warrants
 
Shares
 
Weighted Average Exercise Price
 
Weighted Average Remaining Contractual Term (Years)
 
Aggregate Intrinsic Value (In Thousands)
 
Shares
 
Weighted Average Exercise Price
 
Weighted Average Remaining Contractual Term (Years)
 
Aggregate Intrinsic Value (In Thousands)
Outstanding at December 31, 2013
2,932,191

 
$
11.19

 
6.81 years
 
$
1,658.1

 
4,898,266

 
$
16.50

 
2.63
 
$
1,811.0

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Changes during the Year:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Granted
2,265,850

 
$
6.72

 
 
 
 
 
2,722

 
$
12.26

 
 
 
 
Exercised
(48,987
)
 
$
5.53

 
 
 
 
 
(333,250
)
 
$
5.16

 
 
 
 
Forfeited
(368,704
)
 
$
6.78

 
 
 
 
 
(100,108
)
 
$
70.00

 
 
 
 
Expired
(353,116
)
 
$
12.94

 
 
 
 
 
(916,674
)
 
$
23.95

 
 
 
 
Outstanding at December 31, 2014
4,427,234

 
$
9.19

 
6.93
 
$
28.6

 
3,550,956

 
$
14.12

 
2.12
 
$
1.0

Vested at December 31, 2014 or expected to vest in the future
4,253,465

 
$
9.28

 
6.84
 
$
27.0

 
3,550,956

 
$
14.12

 
2.12
 
$
1.0

Exercisable at December 31, 2014
2,968,379

 
$
10.22

 
6.11
 
$
16.6

 
3,543,456

 
$
14.13

 
2.12
 
$
1.0

The following table summarizes the components of share-based compensation expense for the years ended December 31, 2014 and 2013 ($ in thousands):
 
Year Ended December 31,
 
2014
 
2013
 
2012
Cost of revenues
$
494.2

 
$
314.0

 
$
195.0

Research and development
2,058.2

 
822.2

 
432.9

Selling, general and administrative
8,657.1

 
5,702.5

 
6,084.6

Total share-based compensation expense
$
11,209.5

 
$
6,838.7

 
$
6,712.5

 
 
 
 
 
 
Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block]
Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at December 31, 2014 were as follows ($ in thousands):
 
Stock Options
 
Warrants
 
Restricted Stock
Unrecognized compensation cost
$
4,598.4

 
$
7.2

 
$
528.6

Expected weighted-average period in years of compensation cost to be recognized
3.79

 
0.54

 
0.31
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value [Table Text Block]
Total fair value of shares vested and the weighted average estimated fair values of shares grant for the year ended December 31, 2014, 2013, and 2012 were as follows ($ in thousands):
 
 
Stock Options
 
Warrants
 
 
Year Ended December 31,
 
Year Ended December 31,
 
 
2014
 
2013
 
2012
 
2014
 
2013
 
2012
Total fair value of shares vested
 
$
5,387.1

 
$
3,375.7

 
$
5,408.0

 
$
9.6

 
$
129.0

 
$
171.6

Weighted average estimated fair value of shares granted
 
4.56

 
4.29

 
3.63

 
—

 
3.71

 
4.10
Schedule of Range of Fair Value of Stock Options and Warrants [Table Text Block]
The range of assumptions made in calculating the fair values of stock options and warrants was as follow:
 
 
Stock Options
 
Warrants
 
 
Year Ended December 31,
 
Year Ended December 31,
 
 
2014
 
2013
 
2012
 
2014
 
2013
 
2012
Expected term - minimum (in years)
 
0
 
1
 
2
 
3
 
2
 
2
Expected term - maximum (in years)
 
10
 
10
 
10
 
3
 
5
 
5
Expected volatility - minimum
 
62%
 
61%
 
73%
 
66%
 
73%
 
76%
Expected volatility - maximum
 
77%
 
79%
 
84%
 
66%
 
79%
 
83%
Weighted Average volatility
 
74
%
 
72
%
 
83
%
 
66
%
 
74
%
 
82
%
Expected dividend yield
 
—
 
—
 
—
 
—
 
—
 
—
Risk-free interest rate - minimum
 
0.12%
 
0.13%
 
0.28%
 
0.79%
 
0.32%
 
0.27%
Risk-free interest rate - maximum
 
3.00%
 
2.67%
 
1.99%
 
0.79%
 
1.73%
 
0.88%