10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q

x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

FOR THE QUARTERLY PERIOD ENDED June 30, 2014

OR

o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the Transition Period from __________________   to _________________________

Commission File Number 001-33650

NEOSTEM, INC.

(Exact name of registrant as specified in its charter)

DELAWARE	22-2343568
(State or other jurisdiction of	(I.R.S. Employer
incorporation or organization)	Identification No.)
420 LEXINGTON AVE, SUITE 350 NEW YORK, NEW YORK	10170
(Address of principal executive offices)	(zip code)

Registrant’s telephone number, including area code: 212-584-4180

 (Former name, former address and former fiscal year, if changed since last report)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.   Yes     x         No     o

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).

Yes  x        No     o

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer     o	Accelerated filer     x
Non-accelerated filer   o     (Do not check if a smaller reporting company)	Smaller reporting company     o

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

Yes  o     No  x

35,252,041 SHARES, $.001 PAR VALUE, AS OF August 7, 2014

(Indicate the number of shares outstanding of each of the issuer's classes of common stock, as of the latest practicable date)

CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS

This Quarterly Report on Form 10-Q includes “forward-looking” statements within the meaning of the Private Securities Litigation Reform Act of 1995, as well as historical information. Such forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause our actual results, performance or achievements, or industry results, to be materially different from anticipated results, performance or achievements expressed or implied by such forward-looking statements. When used in this Quarterly Report on Form 10-Q, statements that are not statements of current or historical fact may be deemed to be forward-looking statements. Without limiting the foregoing, the words “plan,” “intend,” “may,” “will,” “expect,” “believe,” “could,” “anticipate,” “estimate,” or “continue” or similar expressions or other variations or comparable terminology are intended to identify such forward-looking statements, although some forward-looking statements are expressed differently. We remind readers that forward-looking statements are merely predictions and therefore inherently subject to uncertaintities and other factors and involve known and unknown risks that could cause the actual results, performance, levels of activity or our achievements or industry results, to be materially different from any future results, performance levels of activity or our achievements or industry results expressed or implied by such forward-looking statements. Factors that could cause our actual results to differ materially from anticipated results expressed or implied by forward-looking statements include, among others:

• our ability to obtain sufficient capital or strategic business arrangements to fund our operations and expansion plans, including meeting our financial obligations under various licensing and other strategic arrangements, the funding of our clinical trials for product candidates in our development programs for our Targeted Immunotherapy Program, our CD34 Cell Program and our T Regulatory Cell Program, and the commercialization of the relevant technology;

• our ability to build and maintain the management and human resources infrastructure necessary to support the growth of our business;

• our ability to integrate our acquired businesses successfully and grow such acquired businesses as anticipated, including expanding our PCT business internationally;

• whether a large global market is established for our cellular-based products and services and our ability to capture a meaningful share of this market;

• scientific and medical developments beyond our control;

• our ability to obtain and maintain, as applicable, appropriate governmental licenses, accreditations or certifications or comply with healthcare laws and regulations or any other adverse effect or limitations caused by government regulation of our business;

• whether any of our current or future patent applications result in issued patents, the scope of those patents and our ability to obtain and maintain other rights to technology required or desirable for the conduct of our business; and our ability to commercialize products without infringing the claims of third party patents;

• whether any potential strategic or financial benefits of various licensing agreements will be realized;

• the results of our development activities, including the results of our planned Phase 3 clinical trial of NBS20, also referred to as DC/TC, being developed to treat metastatic melanoma, our  PreSERVE Phase 2 clinical trial of NBS10, also referred to as AMR-001, being developed to treat acute myocardial infarction and other planned clinical trials;

• our ability to complete our other planned clinical trials (or initiate other trials) in accordance with our estimated timelines due to delays associated with enrolling patients due to the novelty of the treatment, the size of the patient population and the need of patients to meet the inclusion criteria of the trial or otherwise;

• the other factors discussed in “Risk Factors” in our Form 10-K filed with the Securities and Exchange Commission (“the SEC”) on March 13, 2014, and elsewhere in the Annual Report on Form 10-K; and

• the Company’s acquisition of California Stem Cell, Inc. (“CSC Acquisition”) and the ongoing operations associated with this new business will subject the Company to additional risks.  Our Current Report on Form 8-K filed on May 8, 2014 reporting the closing of the CSC Acquisition contains a discussion of the risk factors related to the CSC Acquisition and our new Targeted Immunotherapy Program. 

The factors discussed herein, and in the Company's other periodic filings with the Securities and Exchange Commission (the “SEC”) which are available for review at www.sec.gov under “Search for Company Filings” could cause actual results and developments to be materially different from those expressed or implied by such statements. All forward-looking statements attributable to us are expressly qualified in their entirety by these and other factors. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. Except as required by law, the Company undertakes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.

2

TABLE OF CONTENTS

	PART I- FINANCIAL INFORMATION	Page No.
Item 1.	Consolidated Financial Statements:	4
	Consolidated Balance Sheets at June 30, 2014 and December 31, 2013	4
	Consolidated Statements of Operations for the three and six months ended June 30, 2014 and 2013	5
	Consolidated Statements of Comprehensive Loss for the three and six months ended June 30, 2014 and 2013	6
	Consolidated Statements of Equity for the three and six months ended June 30, 2014 and 2013	7
	Consolidated Statements of Cash Flows for the three and six months ended June 30, 2014 and 2013	8
	Notes to Unaudited Consolidated Financial Statements	9
Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations	23
Item 3.	Quantitative and Qualitative Disclosures About Market Risk	31
Item 4.	Controls and Procedures	31
	PART II- OTHER INFORMATION
Item 1.	Legal Proceedings	33
Item 1A.	Risk Factors	33
Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds	33
Item 3.	Defaults Upon Senior Securities	33
Item 4.	Mine Safety Disclosures	33
Item 5.	Other Information	34
Item 6.	Exhibits	35
	Signatures	36

3

PART I. FINANCIAL INFORMATION

Item 1. Consolidated Financial Statements

NEOSTEM, INC. AND SUBSIDIARIES

CONSOLIDATED BALANCE SHEETS

	June 30, 2014			December 31, 2013
	(Unaudited)
ASSETS
Current Assets
Cash and cash equivalents	$	32,865,071		$	46,133,759
Marketable securities	920,827			—
Accounts receivable, net of allowance for doubtful accounts of $389,809 and $391,829 at June 30, 2014 and December 31, 2013, respectively	2,510,114			1,860,835
Inventory	2,033,011			1,270,223
Prepaid expenses and other current assets	2,525,402			1,561,933
Total current assets	40,854,425			50,826,750
Property, plant and equipment, net	15,639,291			12,844,216
Goodwill	26,079,536			11,117,770
Intangible assets, net	49,363,012			13,875,617
Other assets	1,459,627			1,151,729
Total assets	$	133,395,891		$	89,816,082
LIABILITIES AND EQUITY
Current Liabilities
Accounts payable	$	5,481,229		$	3,354,908
Accrued liabilities	2,587,328			4,018,026
Notes payable	794,236			381,097
Mortgages payable	218,988			213,112
Derivative liabilities	—			23,175
Unearned revenues	2,830,546			1,816,601
Total current liabilities	11,912,327			9,806,919
Long-term Liabilities
Deferred income taxes	18,983,288			4,379,226
Notes payable	1,015,681			531,164
Mortgages payable	2,912,282			3,023,609
Acquisition-related contingent consideration	20,640,000			9,450,000
Other long-term liabilities	635,008			598,729
Total liabilities	56,098,586			27,789,647
Commitments and Contingencies
EQUITY
Stockholders' Equity
Preferred stock, authorized, 20,000,000 shares; Series B convertible redeemable preferred stock liquidation value, 0.01 share of common stock, $.01 par value; 825,000 shares designated; issued and outstanding, 10,000 shares at June 30, 2014 and December 31, 2013	100			100
Common stock, $.001 par value, authorized 500,000,000 shares; issued and outstanding, 34,939,223 and 27,196,537 shares, at June 30, 2014 and December 31, 2013, respectively	34,939			27,197
Additional paid-in capital	341,369,613			299,594,525
Treasury stock, at cost	(705,742		)	(705,742		)
Accumulated deficit	(262,660,679		)	(236,373,605		)
Accumulated other comprehensive income	998			—
Total NeoStem, Inc. stockholders' equity	78,039,229			62,542,475
Noncontrolling interests	(741,924		)	(516,040		)
Total equity	77,297,305			62,026,435
Total liabilities and equity	$	133,395,891		$	89,816,082

See accompanying notes to consolidated financial statements.

4

NEOSTEM, INC. AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF OPERATIONS

 (Unaudited)

	Three Months Ended June 30,						Six Months Ended June 30,
	2014			2013			2014			2013
Revenues	$	4,488,932		$	4,359,406		$	8,544,507		6,883,318
Costs and expenses:
Cost of revenues	3,677,355			4,235,024			7,503,370			6,627,113
Research and development	5,796,022			3,972,127			10,554,535			7,133,453
Selling, general, and administrative	7,446,017			4,322,434			16,416,032			10,124,306
Total operating costs and expenses	16,919,394			12,529,585			34,473,937			23,884,872
Operating loss	(12,430,462		)	(8,170,179		)	(25,929,430		)	(17,001,554		)
Other income (expense):
Other income (expense), net	(185,737		)	57,950			(375,288		)	68,556
Interest expense	(105,906		)	(65,844		)	(200,062		)	(109,405		)
	(291,643		)	(7,894		)	(575,350		)	(40,849		)
Loss before provision for income taxes and noncontrolling interests	(12,722,105		)	(8,178,073		)	(26,504,780		)	(17,042,403		)
Provision for income taxes	47,387			447,568			94,796			447,568
Net loss	(12,769,492		)	(8,625,641		)	(26,599,576		)	(17,489,971		)
Less - loss attributable to noncontrolling interests	(164,474		)	(50,282		)	(312,502		)	(114,036		)
Net loss attributable to NeoStem, Inc. common stockholders	$	(12,605,018	)	(8,575,359		)	$	(26,287,074	)	(17,375,935		)
Basic and diluted loss per share attributable to NeoStem, Inc. common stockholders	$	(0.40	)	(0.46		)	$	(0.88	)	$	(0.99	)
Weighted average common shares outstanding	31,739,417			18,503,236			29,940,128			17,606,051

See accompanying notes to consolidated financial statements.

5

NEOSTEM, INC. AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS

(Unaudited) 

	Three Months Ended June 30,						Six Months Ended June 30,
	2014			2013			2014			2013
Net loss	$	(12,769,492	)	$	(8,625,641	)	$	(26,599,576	)	$	(17,489,971	)
Other comprehensive income:
Available for sale securities - net unrealized gain	998			—			998			—
Total other comprehensive income	998			—			998			—
Comprehensive loss	(12,768,494		)	(8,625,641		)	(26,598,578		)	(17,489,971		)
Comprehensive loss attributable to noncontrolling interests	(164,474		)	(50,282		)	(312,502		)	(114,036		)
Comprehensive net loss attributable to NeoStem, Inc. common stockholders	$	(12,604,020	)	$	(8,575,359	)	$	(26,286,076	)	$	(17,375,935	)

See accompanying notes to consolidated financial statements.

6

NEOSTEM, INC. AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF EQUITY

(Unaudited) 

	Series B Convertible Preferred Stock			Common Stock			Additional Paid in Capital			Accumulated Other Comprehensive Income		Accumulated Deficit			Treasury Stock			Total NeoStem, Inc. Stockholders' Equity			Non- Controlling Interest in Subsidiary			Total Equity
	Shares	Amount		Shares	Amount
Balance at December 31, 2012	10,000	$	100	16,375,365	$	16,375	$	231,218,615		$	—	$	(197,392,361	)	$	(665,600	)	$	33,177,129		$	(356,970	)	$	32,820,159
Net loss	—	—		—	—		—			—		(17,375,935		)	—			(17,375,935		)	(114,036		)	(17,489,971		)
Equity-based compensation	—	—		304,402	304		3,313,893			—		—			—			3,314,197			—			3,314,197
Net proceeds from issuance of common stock	—	—		2,883,847	2,884		14,245,264			—		—			—			14,248,148			—			14,248,148
Proceeds from warrant exercises	—	—		20,761	21		105,860			—		—			—			105,881			—			105,881
Warrant inducements	—	—		—	—		(6,239		)	—		—			—			(6,239		)	—			(6,239		)
Balance at June 30, 2013	10,000	$	100	19,584,375	$	19,584	$	248,877,393		$	—	$	(214,768,296	)	$	(665,600	)	$	33,463,181		$	(471,006	)	$	32,992,175
	Series B Convertible Preferred Stock			Common Stock			Additional Paid in Capital			Accumulated Other Comprehensive Income		Accumulated Deficit			Treasury Stock			Total NeoStem, Inc. Stockholders' Equity			Non- Controlling Interest in Subsidiary			Total Equity
	Shares	Amount		Shares	Amount
Balance at December 31, 2013	10,000	$	100	27,196,537	$	27,197	$	299,594,525		$	—	$	(236,373,605	)	$	(705,742	)	$	62,542,475		$	(516,040	)	$	62,026,435
Net loss	—	—		—	—		—			—		(26,287,074		)	—			(26,287,074		)	(312,502		)	(26,599,576		)
Unrealized gain on marketable securities	—	—		—	—		—			998		—			—			998			—			998
Equity-based compensation	—	—		456,709	457		5,652,994			—		—			—			5,653,451			—			5,653,451
Net proceeds from issuance of common stock	—	—		1,650,081	1,650		10,147,788			—		—			—			10,149,438			—			10,149,438
Proceeds from option exercises	—	—		41,136	41		230,142			—		—			—			230,183			—			230,183
Proceeds from warrant exercises	—	—		265,250	264		1,373,661			—		—			—			1,373,925			—			1,373,925
Shares issued in CSC acquisition	—	—		5,329,510	5,330		24,457,121			—		—			—			24,462,451			—			24,462,451
Change in ownership in subsidiary	—	—		—	—		(86,618		)	—		—			—			(86,618		)	86,618			—
Balance at June 30, 2014	10,000	$	100	34,939,223	$	34,939	$	341,369,613		$	998	$	(262,660,679	)	$	(705,742	)	$	78,039,229		$	(741,924	)	$	77,297,305

See accompanying notes to consolidated financial statements.

7

NEOSTEM, INC. AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF CASH FLOWS

(Unaudited)

	Six Months Ended June 30,
	2014			2013
Cash flows from operating activities:
Net loss	$	(26,599,576	)	$	(17,489,971	)
Adjustments to reconcile net loss to net cash used in operating activities:
Equity-based compensation expense	5,653,451			3,314,197
Depreciation and amortization	987,698			832,920
Changes in fair value of derivative liability	(23,175		)	(68,556		)
Change in acquisition-related contingent consideration	400,000			—
Bad debt recovery	(2,020		)	(7,178		)
Deferred income taxes	94,796			447,568
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(944,297		)	(190,150		)
Accounts receivable	(602,132		)	359,163
Inventory	(762,788		)	1,081,060
Unearned revenues	1,013,946			(1,106,299		)
Other assets	(106,909		)	(25,805		)
Accounts payable, accrued expenses and other liabilities	(1,615,234		)	(272,718		)
Net cash used in operating activities	(22,506,240		)	(13,125,769		)
Cash flows from investing activities:
Net cash received in acquisitions	50,894			—
Purchase of marketable securities	(919,829		)	—
Acquisition of property and equipment	(2,439,266		)	(268,535		)
Net cash used in investing activities	(3,308,201		)	(268,535		)
Cash flows from financing activities:
Proceeds from exercise of options	230,183			—
Proceeds from exercise of warrants	1,373,925			105,881
Net proceeds from issuance of common stock	10,149,439			14,248,148
Repayment of mortgage loan	(105,450		)	(93,070		)
Proceeds from notes payable	1,340,981			221,218
Repayment of notes payable	(443,325		)	(96,608		)
Payment for warrant inducement	—			(6,239		)
Net cash provided by financing activities	12,545,753			14,379,330
Net (decrease) increase in cash and cash equivalents	(13,268,688		)	985,026
Cash and cash equivalents at beginning of period	46,133,759			13,737,452
Cash and cash equivalents at end of period	$	32,865,071		$	14,722,478
Supplemental Disclosure of Cash Flow Information:
Cash paid during the period for:
Interest	$	196,200		$	126,000
Taxes	—			—
Supplemental schedule of non-cash financing activities:
Common stock and contingent consideration issued with the acquisition of CSC	$	35,252,451		$	—

See accompanying notes to consolidated financial statements.

8

NEOSTEM, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

Note 1  – The Business

Overview

NeoStem, Inc. (“we,” “NeoStem” or the “Company”) is a leader in the emerging cellular therapy industry. We are pursuing the preservation and enhancement of human health globally through the development of cell based therapeutics that prevent, treat or cure disease. We have multiple cell therapy platforms that work to address the pathology of disease using a person's own cells to amplify the body's natural repair mechanisms including enhancing the destruction of cancer initiating cells, repairing and replacing damaged or aged tissue, cells and organs and restoring their normal function. We believe that cell therapy will play a large role in changing the natural history of diseases as more breakthrough therapies are developed, ultimately lessening the overall burden of disease on patients and their families as well as the economic burden that these diseases impose upon modern society.

Our business includes the development of novel proprietary cell therapy products, as well as a revenue-generating contract development and manufacturing service business that we leverage for the development of our therapeutics while providing service to other companies in the cell therapy industry. The combination of our own therapeutic development business and a revenue-generating service provider business provides the Company with unique capabilities for cost effective in-house product development and immediate revenue and future cash flow to help underwrite our internal development programs. This business model enables the Company to be opportunistic in growing its pipeline as evidenced by the Company's acquisition in May 2014 of California Stem Cell, Inc. ("CSC"), a cell biotechnology corporation that is developing cellular immunotherapies for cancer, an area we view to be one of the most promising sub-sectors in biotechnology. The lead product candidate in its immunotherapy pipeline is NBS20, also referred to as DC/TC (dendritic cell/tumor cell), and is targeting malignant melanoma initiating cells. This immunotherapy designed to treat Stage IV or recurrent Stage III metastatic melanoma, which has been granted fast track and orphan designation by the Food and Drug Administration ("FDA"), also has a Phase 3 protocol that is the subject of a Special Protocol Assessment ("SPA"). The SPA, indicates that the FDA is in agreement with the design, clinical endpoints, and planned clinical analyses of the Phase 3 trial that would serve as the basis for a Biologics License Application ("BLA") that would be filed with the FDA requesting marketing approval of this therapeutic candidate. This protocol calls for enrolling 250 evaluable patients and is expected to be initiated later in 2014. We are evaluating other clinical indications into which we may advance this program, including liver, ovarian and lung cancers.

We are also currently developing therapies to address ischemia through utilizing CD34 cells. Ischemia occurs when the supply of oxygenated blood in the body is restricted. We seek to reverse this restriction through the development and formation of new blood vessels. NBS10, also referred to as AMR-001, is our most clinically advanced product candidate in our ischemic repair program and is being developed to treat damaged heart muscle following an acute myocardial infarction (heart attack) ("AMI"). In December 2013, the Company completed enrollment in its PreSERVE AMI study. PreSERVE AMI is a randomized, double-blinded, placebo-controlled Phase 2 clinical trial testing NBS10, an autologous (donor and recipient are the same) adult stem cell product for the treatment of patients with left ventricular dysfunction following acute ST segment elevation myocardial infarction (STEMI). The last patient in the trial was infused in December 2013 and the last patient six-month follow-up occurred in June 2014. Once the primary end point six-month data is collected, the data set will be locked and analysis will begin.   An abstract for the PreSERVE AMI study has been accepted for presentation at the American Heart Association's Scientific Sessions being held November 15-19, 2014 although we anticipate results of the study will be released earlier. If approved by the FDA and/or other worldwide regulatory agencies following successful completion of further trials, NBS10 would address a significant medical need for which there is currently no effective treatment, potentially improving longevity and quality of life for those suffering a STEMI, and positioning the Company to capture a meaningful share of this worldwide market. We are evaluating other clinical indications into which we may advance this program, including traumatic brain injury ("TBI"), congestive heart failure ("CHF"), and critical limb ischemia ("CLI").

Another platform technology we are developing utilizes T Regulatory Cells ("Tregs") to treat diseases caused by imbalances in an individual's immune system.  Collaborating with the University of California, San Francisco, we are utilizing the technology platform of our majority-owned subsidiary, Athelos Corporation ("Athelos"), to restore immune balance by enhancing Treg cell number and function.  Tregs are a natural part of the human immune system and regulate the activity of T effector cells, the cells that are responsible for protecting the body from viruses and other foreign antigens. When Tregs function properly, only harmful foreign materials are attacked by T effector cells. In autoimmune disease it is thought that deficient Treg activity permits the T effector cells to attack the body's own tissues, while in allergic diseases, like asthma, it is though that the immune system overreacts to harmless foreign substances. We plan to initiate in 2014, subject to review and approval of the protocols by the appropriate regulatory authorities, a Phase 2 study of NBS03D, a Treg based therapeutic, in the treatment of type

9

1 diabetes, and a Phase 1 study in Canada of NBS03A, a Treg based therapeutic, in support of our steroid resistant asthma development program.

Pre-clinical assets include our VSEL ^TM (Very Small Embryonic Like) Technology regenerative medicine platform. Regenerative medicine holds the promise of improving clinical outcomes and reducing overall  healthcare costs.  We are working on a Department of Defense funded study of VSELs^TM for the treatment of chronic wounds. Other preclinical work with VSELs^TM includes exploring macular degeneration as a target indication.

Progenitor Cell Therapy, LLC ("PCT") is a contract manufacturer in the cellular therapy industry that generates revenue. This wholly owned subsidiary, which we acquired in 2011, is an industry leader in providing high quality manufacturing capabilities and support to developers of cell-based therapies to enable them to improve efficiencies and profitability and reduce the capital investment required for their own development activities. Since its inception more than 15 years ago, PCT has provided pre-clinical and clinical current Good Manufacturing Practice (“cGMP”) development and manufacturing services to more than 100 clients. PCT has experience advancing regenerative medicine product candidates from product inception through rigorous quality standards all the way through to human testing, BLA filing and FDA product approval. PCT's core competencies in the cellular therapy industry include manufacturing of cell therapy-based products, engineering and innovation services, product and process development, cell and tissue processing, regulatory support, storage, distribution and delivery and consulting services. PCT has two cGMP, state-of-the art cell therapy research, development, and manufacturing facilities in New Jersey and California, serving the cell therapy community with integrated and regulatory compliant distribution capabilities. The Company is pursuing commercial expansion of our manufacturing operations both in the U.S. and internationally. Additionally, with our acquisition of CSC in Irvine, California, we are now in a position to leverage NeoStem Oncology's expertise in immunotherapy and advance our platform technology, as well as the technologies of PCT's client base.

Strategic acquisitions have been the cornerstone of NeoStem’s growth and have been selected in order to provide value to stockholders by taking advantage of the infrastructure we have created which includes strong development, regulatory and manufacturing expertise. By adding NBS20, our DC/TC product candidate and a late stage novel proprietary cancer cell therapy into our pipeline, we look to further advance towards our goal of delivering transformative cell based therapies to the market to help patients suffering from life-threatening medical conditions. Coupled with our strong manufacturing capability, we believe the stage is set for us to realize meaningful clinical development and manufacturing efficiencies, further positioning NeoStem to lead the cell therapy industry.

Basis of Presentation

The accompanying unaudited Consolidated Financial Statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“generally accepted accounting principles”) for interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation S-X of the Securities and Exchange Commission for interim financial information. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, the accompanying Consolidated Financial Statements of the Company and its subsidiaries, which are unaudited, include all normal and recurring adjustments considered necessary to present fairly the Company’s financial position as of June 30, 2014 and the results of its operations and its cash flows for the periods presented. The unaudited consolidated financial statements herein should be read together with the historical consolidated financial statements of the Company for the years ended December 31, 2013 and 2012 included in our Annual Report on Form 10-K for the year ended December 31, 2013. Operating results for the six months endedJune 30, 2014 are not necessarily indicative of the results that may be expected for the year ending December 31, 2014.

Use of Estimates

The preparation of financial statements in conformity with generally accepted accounting principles in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the consolidated financial statements. Estimates also affect the reported amounts of revenues and expenses during the reporting period. Accordingly, actual results could differ from those estimates.

Reclassifications

Certain reclassifications have been made to the Consolidated Financial Statements and Notes to the Consolidated Financial Statements for the three and six months endedJune 30, 2013 to conform to the presentation for the three and six months endedJune 30, 2014.

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Principles of Consolidation

The Consolidated Financial Statements include the accounts of NeoStem, Inc. and its wholly owned and partially owned subsidiaries and affiliates as listed below.

Entity	Percentage of Ownership	Location
NeoStem, Inc.	Parent  Company	United States of America
NeoStem Therapies, Inc.	100%	United States of America
Stem Cell Technologies, Inc.	100%	United States of America
Amorcyte, LLC	100%	United States of America
Progenitor Cell Therapy, LLC (PCT)	100%	United States of America
NeoStem Family Storage, LLC	100%	United States of America
Athelos Corporation (1)	90%	United States of America
PCT Allendale, LLC	100%	United States of America
NeoStem Oncology, LLC (2)	100%	United States of America

(1) Pursuant to the Stock Purchase Agreement signed in March 2011, our initial ownership in Athelos was 80.1%, and Becton Dickinson's ("BD") initial minority ownership was 19.9%. Per the Agreement, BD will be diluted based on new investment in Athelos by us (subject to certain anti-dilution provisions). As of June 30, 2014, BD's ownership interest in Athelos was decreased to 10.0%, and our ownership increased to 90.0%. As a result in the change in ownership, approximately $0.1 million was transferred from additional paid in capital to non-controlling interests.

(2) On May 8, 2014, NeoStem acquired CSC, now known as NeoStem Oncology, LLC (see Note 3, Acquisition). Accordingly, the operating results of NeoStem Oncology, LLC prior to May 8, 2014 are not included in the Company's consolidated operations and cash flows.

Note 2 – Summary of Significant Accounting Policies

In addition to the policies below, our significant accounting policies are described in Note 2 of the Notes to Consolidated Financial Statements included in our Annual Report on Form 10-K for the year ended December 31, 2013. There were no changes during the six months endedJune 30, 2014.

Cash and Cash Equivalents

Cash and cash equivalents include short-term, highly liquid, investments with maturities of ninety days or less when purchased.

Marketable Securities

The Company determines the appropriate classification of our marketable securities at the time of purchase and reevaluate such designation at each balance sheet date. All of our marketable securities are considered as available-for-sale and carried at estimated fair values and reported in either cash equivalents or marketable securities. Unrealized gains and losses on available-for-sale securities are excluded from net income and reported in accumulated other comprehensive income (loss) as a separate component of stockholders' equity. Other income (expense), net, includes interest, dividends, amortization of purchase premiums and discounts, realized gains and losses on sales of securities and other-than-temporary declines in the fair value of securities, if any. The cost of securities sold is based on the specific identification method. We regularly review all of our investments for other-than-temporary declines in fair value. Our review includes the consideration of the cause of the impairment, including the creditworthiness of the security issuers, the number of securities in an unrealized loss position, the severity and duration of the unrealized losses, whether we have the intent to sell the securities and whether it is more likely than not that we will be required to sell the securities before the recovery of their amortized cost basis. When we determine that the decline in fair value of an investment is below our accounting basis and this decline is other-than-temporary, we reduce the carrying value of the security we hold and record a loss for the amount of such decline.

Accounts Receivable

Accounts receivable are carried at original invoice amount less an estimate made for doubtful accounts. The Company applies judgment in connection with establishing the allowance for doubtful accounts. Specifically, the Company analyzes the aging of accounts receivable balances, historical bad debts, customer concentration and credit-worthiness, current economic trends and changes in the Company’s customer payment terms. Significant changes in customer concentrations or payment terms, deterioration of customer credit-worthiness or weakening economic trends could have a significant impact on the collectability of the receivables

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and the Company’s operating results. If the financial condition of the Company’s customers were to deteriorate, resulting in an impairment of their ability to make payments, additional allowances may be required. Management regularly reviews the aging of receivables and changes in payment trends by its customers, and records a reserve when it believes collection of amounts due are at risk.

Inventories

The Company, through its PCT subsidiary, regularly enters into contracts with clients for services that have multiple stages and are dependent on one another to complete the contract and recognize revenue. The Company's inventory primarily represents work in process for costs incurred on such projects at PCT that have not been completed. The Company reviews these projects periodically to determine that the value of each project is stated at the lower of cost or market.

Goodwill and Other Intangible Assets

Goodwill is the excess of purchase price over the fair value of identified net assets of businesses acquired. The Company’s intangible assets with an indefinite life are related to in process research and development ("IPR&D") programs acquired in the Amorcyte and CSC acquisitions, as the Company expects future research and development on these programs to provide the Company with substantial benefit for a period that extends beyond the foreseeable horizon. Intangible assets with indefinite useful lives are measured at their respective fair values as of the acquisition date. The Company does not amortize goodwill and intangible assets with indefinite useful lives. Intangible assets related to IPR&D projects are considered to be indefinite-lived until the completion or abandonment of the associated R&D efforts. If and when development is complete, which generally occurs if and when regulatory approval to market a product is obtained, the associated assets would be deemed finite-lived and would then be amortized based on their respective estimated useful lives at that point in time.

The Company reviews goodwill and indefinite-lived intangible assets at least annually for possible impairment. Goodwill and indefinite-lived intangible assets are reviewed for possible impairment between annual tests if an event occurs or circumstances change that would more likely than not reduce the fair value of the reporting unit below its carrying value. The Company tests its goodwill and indefinite-lived intangible assets each year on December 31. The Company reviews the carrying value of goodwill and indefinite-lived intangible assets utilizing a discounted cash flow model, and, where appropriate, a market value approach is also utilized to supplement the discounted cash flow model. The Company makes assumptions regarding estimated future cash flows, discount rates, long-term growth rates and market values to determine each reporting unit’s estimated fair value.

Amortized intangible assets consist of customer lists, manufacturing technology, tradenames, patents and rights. These intangible assets are amortized on a straight line basis over their respective useful lives.

Revenue Recognition

Clinical Services: The Company recognizes revenue for its (i) process development and (ii) clinical manufacturing services based on the terms of individual contracts.

Revenues associated with process development services generally contain multiple stages that do not have stand-alone values and are dependent upon one another, and are recognized as revenue on a completed contract basis. We recognize revenues when all of the following conditions are met:

• persuasive evidence of an arrangement exists;

• delivery has occurred or the services have been rendered;

• the fee is fixed or determinable; and

• collectability is probable.

The Company considers signed contracts as evidence of an arrangement. The Company assesses whether the fee is fixed or determinable based on the payment terms associated with the transaction and whether the payment terms are subject to refund or adjustment. The Company assesses cash collectability based on a number of factors, including past collection history with the client and the client's creditworthiness. If the Company determines that collectability is not reasonably assured, it defers revenue recognition until collectability becomes reasonably assured, which is generally upon receipt of the cash. The Company's

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arrangements are generally non-cancellable, though clients typically have the right to terminate their agreement for cause if the Company materially fails to perform.

Clinical manufacturing services are generally distinct arrangements whereby the Company is paid for time and materials or for fixed monthly amounts. Revenue is recognized when efforts are expended or contractual terms have been met.

Some client agreements include multiple elements, comprised of process development and clinical manufacturing services. The Company believes that process development and clinical manufacturing services each have stand-alone value because these services can be provided separately by other companies. In accordance with ASC Update No. 2009-13, “Revenue Recognition (Topic 605): Multiple-Deliverable Revenue Arrangements,” the Company (1) separates deliverables into separate units of accounting when deliverables are sold in a bundled arrangement and (2) allocates the arrangement's consideration to each unit in the arrangement based on its relative selling price. 

Clinical Services Reimbursements: The Company separately charges the customers for the expenses associated with certain consumable resources (reimbursable expenses) that are specified in each clinical services contract. On a monthly basis, the Company bills customers for reimbursable expenses and immediately recognizes these billings as revenue, as the revenue is deemed earned as reimbursable expenses are incurred. For the three months endedJune 30, 2014 and 2013, clinical services reimbursements were $1.1 million and $0.4 million, respectively. For the six months endedJune 30, 2014 and 2013, clinical services reimbursements were $1.8 million and $0.8 million, respectively.

Processing and Storage Services: The Company recognizes revenue related to the collection and cryopreservation of cord blood and autologous adult stem cells when the cryopreservation process is completed which is approximately twenty-four hours after cells have been collected. Revenue related to advance payments of storage fees is recognized ratably over the period covered by the advance payments.

New Accounting Pronouncement

In May 2014, the FASB issued ASU 2014-09, "Revenue from Contracts with Customers (Topic 606)." The new revenue recognition standard provides a five-step analysis to determine when and how revenue is recognized. The standard requires that a company recognizes revenue to depict the transfer of promised goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods or services. This ASU is effective for annual periods beginning after December 15, 2016 and will be applied retrospectively to each period presented or as a cumulative-effect adjustment as of the date of adoption. The Company is currently evaluating the impact of the pending adoption of ASU 2014-09 on its consolidated financial statements.

Note 3 – Acquisition

On May 8, 2014 (the “Closing”), NeoStem closed its acquisition of CSC (the “CSC Acquisition”), pursuant to the terms of the Agreement and Plan of Merger, dated as of April 11, 2014 (the “Merger Agreement”), by and among NeoStem, CSC, NBS Acquisition Sub I, Inc., a Delaware corporation and a wholly-owned subsidiary of NeoStem (“Subco”), NBS Acquisition Sub II, LLC, a Delaware limited liability company and a wholly-owned subsidiary of NeoStem (“Subco II”), and Jason Livingston, solely in his capacity as CSC stockholder representative (together with his permitted successors, the “CSC Representative”). At Closing, Fortis Advisors LLC succeeded to the duties of the CSC Representative pursuant to the Merger Agreement.

Pursuant to the Merger Agreement, on the Closing Date, (1) Subco was merged with and into CSC (the “First Merger”) and (2) CSC was then merged with and into Subco II (the “Second Merger”, and collectively with the First Merger, the “Mergers”), with Subco II surviving the Mergers as a wholly-owned subsidiary of NeoStem. At Closing, Subco II changed its legal name to NeoStem Oncology, LLC.

CSC is a biopharmaceutical company with deep expertise in stem cell biology that is engaged in the development of therapies using a patient’s own, i.e., autologous, cells. Its development efforts are primarily directed at immunotherapies for cancer. Its most advanced program is an immunotherapy, NBS20, also referred to as DC/TC (dendritic cell/tumor cell), which uses patients’ own tumor cells to maximize the ability of their immune system to identify and eliminate the cancer initiating cells that are capable of reconstituting or developing new tumors (i.e., “cancer stem cells” or “replicating cells”). The current focus of that program is the treatment of metastatic melanoma. As a result of encouraging Phase 2 data, the Company expects to initiate a Phase 3 clinical trial later in 2014, for which it has received Special Protocol Assessment (“SPA”) and Fast Track designation, as well as Orphan Drug designation.

Aggregate Merger Consideration

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Pursuant to the terms of the Merger Agreement, all shares of CSC common stock (“CSC Common Stock”) and CSC preferred stock (“CSC Preferred Stock”, and collectively with the CSC Common Stock, the “CSC Capital Stock”) outstanding immediately prior to the Closing, and all outstanding unexercised options to purchase CSC Common Stock (“CSC Options”) (treated as if a net exercise had occurred), were canceled and converted into the right to receive, in the aggregate (and giving effect to the liquidation preferences accorded to the CSC Preferred Stock):

(1)An aggregate of 5,329,593 shares of NeoStem common stock (subject to payment of nominal cash in lieu of fractional shares) (the “Closing Merger Consideration”).

(2)if payable after the Closing, certain payments in an amount of up to $90.0 million in the aggregate, payable in shares of NeoStem Common Stock or cash, in NeoStem’s sole discretion, in the event of the successful completion of certain milestone events in connection with the CSC business being acquired by NeoStem (the “Milestone Payments”, and together with the Closing Merger Consideration, the “Merger Consideration”).

The fair value of the net assets acquired in the CSC Acquisition was $20.3 million. The fair value of the consideration paid by NeoStem was valued at $35.3 million, resulting in the recognition of goodwill in the amount of $15.0 million. The consideration paid was comprised of equity issued and milestone payments. The fair value of the equity issued by NeoStem was valued at $24.5 million. The fair value of the milestone payments was valued at $10.8 million, and is contingent on the achievement of certain milestones associated with the future development of the acquired programs. Such contingent consideration has been classified as a liability and will be subject to remeasurement.

The preliminary fair value of assets acquired and liabilities assumed on May 8, 2014 is as follows (in thousands):

Cash and cash equivalents	$	51.2
Accounts receivable trade, net	45.1
Prepaids and other current assets	19.2
Property, plant and equipment, net	1,040.9
Other assets	201.0
Goodwill	14,961.9
In-Process R&D	35,790.0
Accounts payable	(333.1		)
Accrued liabilities	(2,014.1		)
Deferred tax liability	(14,509.3		)
	$	35,252.8

The total cost of the acquisition, which is still preliminary, has been allocated to the assets acquired and the liabilities assumed based upon their estimated fair values at the date of the acquisition. The final allocation is pending the receipt of a third-party valuation and the completion of the Company’s internal review, which is expected during fiscal 2014.

For the period since the acquisition (May 9, 2014 to June 30, 2014), NeoStem recorded $0.01 million in revenues and a net loss of approximately $2.3 million or $0.07 basic and diluted loss per share attributable to CSC.

Pro Forma Financial Information

The following supplemental table presents unaudited consolidated pro forma financial information as if the closing of the acquisition of CSC had occurred on January 1, 2013 (in thousands, except per share amounts):

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	Three Months Ended June 30, 2014						Six Months Ended June 30, 2014
	(As Reported)			(Proforma)			(As Reported)			(Proforma)
Revenues	$	4,489		$	4,982		$	8,545		$	9,255
Net loss	$	(12,770	)	$	(13,574	)	$	(26,600	)	$	(29,097	)
Net loss attributable to NBS	$	(12,605	)	$	(13,409	)	$	(26,287	)	$	(28,784	)
Net loss per share attributable to NBS	$	(0.40	)	$	(0.36	)	$	(0.88	)	$	(0.82	)

	Three Months Ended June 30, 2013						Six Months Ended June 30, 2013
	(As Reported)			(Proforma)			(As Reported)			(Proforma)
Revenues	$	4,359		$	4,596		$	6,883		$	7,282
Net loss	$	(8,626	)	$	(9,830	)	$	(17,490	)	$	(19,963	)
Net loss attributable to NBS	$	(8,575	)	$	(9,780	)	$	(17,376	)	$	(19,849	)
Net loss per share attributable to NBS	$	(0.46	)	$	(0.41	)	$	(0.99	)	$	(0.87	)

The unaudited supplemental pro forma financial information should not be considered indicative of the results that would have occurred if the acquisition of CSC had been consummated on January 1, 2013, nor are they indicative of future results.

Note 4 – Available-for-Sale-Securities

The following table is a summary of available-for-sale securities recorded in cash and cash equivalents or marketable securities in our Consolidated Balance Sheets (in thousands):

	June 30, 2014
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Estimated Fair Value
Certificate of deposits	$	744.0	$	—	$	—		$	744.0
Money market funds	21,051.0		—		—			21,051.0
Municipal debt securities	6,581.3		1.1		(0.1		)	6,582.3
Total	$	28,376.3	$	1.1	$	(0.1	)	$	28,377.3

Estimated fair values of available-for-sale securities are generally based on prices obtained from commercial pricing services. The following table summarizes the classification of the available-for-sale debt securities on our Consolidated Balance Sheets (in thousands):

	June 30, 2014
Cash and cash equivalents	$	27,456.5
Marketable securities	920.8
Total	$	28,377.3

The following table summarizes our portfolio of available-for-sale debt securities by contractual maturity (in thousands):

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	June 30, 2014
	Amortized Cost		Estimated Fair Value
Less than one year	$	28,376.3	$	28,377.3
Greater than one year	—		—
Total	$	28,376.3	$	28,377.3

Note 5 – Inventories

Inventories, primarily representing work in process for costs incurred on projects at PCT that have not been completed, were $2.0 million and $1.3 million as of June 30, 2014 and December 31, 2013, respectively. The Company also has deferred revenue of approximately $2.4 million and $1.5 million of advance billings received as of June 30, 2014 and December 31, 2013, respectively, related to these contracts.

Note 6 – Loss Per Share

For the six months endedJune 30, 2014 and 2013, the Company incurred net losses and therefore no common stock equivalents were utilized in the calculation of loss per share. At June 30, 2014 and 2013, the Company excluded the following potentially dilutive securities:

	June 30,
	2014	2013
Stock Options	4,204,270	2,647,437
Warrants	3,623,956	5,430,137
Restricted Shares	205,231	73,500

Note 7 – Fair Value Measurements

Fair value of financial assets and liabilities that are being measured and reported are defined as the exchange price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants in the principal market at the measurement date (exit price). The Company is required to classify fair value measurements in one of the following categories:

Level 1 inputs are defined as quoted prices (unadjusted) in active markets for identical assets or liabilities that the reporting entity has the ability to access at the measurement date.

Level 2 inputs are defined as inputs other than quoted prices included within Level 1 that are observable for the assets or liabilities, either directly or indirectly.

Level 3 inputs are defined as unobservable inputs for the assets or liabilities. Financial assets and liabilities are classified based on the lowest level of input that is significant to the fair value measurement. The Company’s assessment of the significance of a particular input to the fair value measurement requires judgment, and may affect the valuation of the fair value of assets and liabilities and their placement within the fair value hierarchy levels.

The Company classifies the fair value of the warrant derivative liabilities as level 3 inputs. These inputs require material subjectivity because value is derived through the use of a lattice model that values the derivatives based on probability weighted discounted cash flows. In May 2014, the warrants expired and the value of the warrant derivative liabilities were written off and recorded in other expenses in our consolidated statement of operations.

The Company classifies the fair value of contingent consideration obligations as level 3 inputs. The Company has recognized contingent consideration obligations related to the following:

• In October 2011, in connection with the Company's acquisition of Amorcyte, contingent consideration obligations were recognized relating to earn out payments equal to 10% of the net sales of the lead product candidate NBS10 (in the event of and following the date of first commercial sale of NBS10), provided that in the event NeoStem sublicenses NBS10,

16

the applicable earn out payment will be equal to 30% of any sublicensing fees, and provided further that NeoStem will be entitled to recover direct out-of-pocket clinical development costs not previously paid or reimbursed and any costs, expenses, liabilities and settlement amounts arising out of claims of patent infringement or otherwise challenging Amorcyte’s right to use intellectual property, by reducing any earn out payments due by 50% until such costs have been recouped in full (the “Earn Out Payments”). The contingent consideration fair value increased from $9.5 million as of December 31, 2013 to $9.9 million as of June 30, 2014. The change in estimated fair value is based or the impact of the time progression through the Phase 2 clinical trial from December 31, 2013 to June 30, 2014, and has been recorded in other expenses in our consolidated statement of operations.

• In May 2014, in connection with the Company's acquisition of CSC, contingent consideration obligations were recognized relating to milestone payments of up to $90.0 million, based on the achievement of certain milestones associated with the future development of the acquired programs. The contingent consideration fair value recognized in the acquisition in May 2014 was $10.8 million. There was no change in estimated fair value as of June 30, 2014.

The fair value of contingent consideration obligations is based on discounted cash flow models using a probability-weighted income approach. The measurements are based upon unobservable inputs supported by little or no market activity based on our own assumptions and experience. The Company bases the timing to complete the development and approval programs on the current development stage of the product and the inherent difficulties and uncertainties in developing a product candidate, such as obtaining U.S. Food and Drug Administration (FDA) and other regulatory approvals. In determining the probability of regulatory approval and commercial success, we utilize data regarding similar milestone events from several sources, including industry studies and our own experience. These fair value measurements represent Level 3 measurements as they are based on significant inputs not observable in the market. Significant judgment is employed in determining the appropriateness of these assumptions as of the acquisition date and for each subsequent period. Accordingly, changes in assumptions could have a material impact on the amount of contingent consideration expense we record in any given period.

The following table sets forth by level within the fair value hierarchy the Company’s financial assets and liabilities that were accounted for at fair value on a recurring basis as of June 30, 2014, and December 31, 2013 (in thousands):

	June 30, 2014								December 31, 2013
	Level 1		Level 2		Level 3		Total		Level 1		Level 2		Level 3		Total
Assets:
Marketable securities - available for sale	$	—	$	920.8	$	—	$	920.8	$	—	$	—	$	—	$	—
	$	—	$	920.8	$	—	$	920.8	$	—	$	—	$	—	$	—
Liabilities:
Warrant derivative liabilities	$	—	$	—	$	—	$	—	$	—	$	—	$	23.2	$	23.2
Contingent consideration	—		—		20,640.0		20,640.0		—		—		9,450.0		9,450.0
	$	—	$	—	$	20,640.0	$	20,640.0	$	—	$	—	$	9,473.2	$	9,473.2

For those financial instruments with significant Level 3 inputs, the following table summarizes the activity for the six months endedJune 30, 2014 by type of instrument (in thousands):

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	Six Months Ended
	June 30, 2014
	Warrants			Contingent Consideration		Total
Beginning liability balance	$	23.2		$	9,450.0	$	9,473.2
Amount issued in acquisition	—			10,790.0		10,790.0
Change in fair value recorded in earnings	—			400.0		400.0
Expiration	(23.2		)	—		(23.2		)
Ending liability balance	$	—		$	20,640.0	$	20,640.0

Some of the Company’s financial instruments are not measured at fair value on a recurring basis, but are recorded at amounts that approximate fair value due to their liquid or short-term nature, such as cash and cash equivalents, accounts receivable, accounts payable. Our long-term debt and notes payable are carried at cost and approximate fair value due to their variable or fixed interest rates, which are consistent with the interest rates in the market.

Note 8 – Goodwill and Other Intangible Assets

The following table summarizes the changes in the carrying amount of goodwill (in thousands):

	Total
Balance as of December 31, 2013	$	11,117.7
Goodwill resulting from the acquisition of CSC	14,961.8
Balance as of June 30, 2014	$	26,079.5

The Company's intangible assets and related accumulated amortization as of June 30, 2014 and December 31, 2013 consisted of the following (in thousands):

		June 30, 2014							December 31, 2013
	Useful Life	Gross		Accumulated Amortization			Net		Gross		Accumulated Amortization			Net
Customer list	10 years	$	1,000.0	$	(345.1	)	$	654.9	$	1,000.0	$	(295.1	)	$	704.9
Manufacturing technology	10 years	3,900.0		(1,345.9		)	2,554.1		3,900.0		(1,150.9		)	2,749.1
Tradename	10 years	800.0		(276.1		)	523.9		800.0		(236.1		)	563.9
In process R&D	Indefinite	45,190.0		—			45,190.0		9,400.0		—			9,400.0
Patent rights	19 years	669.0		(228.9		)	440.1		669.0		(211.3		)	457.7
Total Intangible Assets		$	51,559.0	$	(2,196.0	)	$	49,363.0	$	15,769.0	$	(1,893.4	)	$	13,875.6

Total intangible amortization expense was classified in the operating expense categories for the periods included below as follows (in thousands):

	Six Months Ended June 30,
	2014		2013
Cost of revenue	$	158.4	$	195.0
Research and development	54.2		17.6
Selling, general and administrative	90.0		90.0
Total	$	302.6	$	302.6

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Estimated intangible amortization expense on an annual basis for the succeeding five years is as follow (in thousands):

2014	$	302.6
2015	605.2
2016	605.2
2017	605.2
2018	605.2
Thereafter	46,639.6
	$	49,363.0

Note 9 – Accrued Liabilities

Accrued liabilities as of June 30, 2014 and December 31, 2013 were as follows (in thousands):

	June 30, 2014		December 31, 2013
Salaries, employee benefits and related taxes	$	1,443.2	$	2,325.8
Professional fees	651.7		544.8
License fees	100.0		500.0
Other	392.4		647.4
	$	2,587.3	$	4,018.0

Note 10 – Debt

Notes Payable

As of June 30, 2014 and December 31, 2013, the Company had notes payable of approximately $1.8 million and $0.9 million, respectively. The notes relate to certain insurance policies and equipment financings, require monthly payments, and mature within one to three years.

Mortgages Payable

In October 2007, PCT issued a note to borrow $3.1 million (the “First Mortgage”) in connection with its $3.8 million purchase of condominium units in an existing building in Allendale, New Jersey (the “Property”). The First Mortgage is payable in 239 consecutive monthly payments of principal and interest, based on a 20 year amortization schedule; and one final payment of all outstanding principal plus accrued interest then due. The current monthly installment is $20,766, which includes interest at an initial rate of 5.00%; the interest rate and monthly installments payments are subject to adjustment on October 1, 2017. On that date, upon prior written notice, the lender has the option to declare the entire outstanding principal balance, together with all outstanding interest, due and payable in full. The First Mortgage is secured by substantially all of the assets of PCT, including a first mortgage on the Property and assignment of an amount approximately equal to eighteen months debt service held in escrow. The Note matures on October 1, 2027 if not called by the lender on October 1, 2017. The First Mortgage had previously been subject to certain debt service coverage and total debt to tangible net worth financial covenant ratios measured semi-annually. The outstanding balance was approximately $2.4 million and $2.5 million at June 30, 2014 and December 31, 2013, respectively, of which $130,000 is payable within twelve months as of June 30, 2014.

In December 2010 PCT Allendale, a wholly-owned subsidiary of PCT, entered into a note for a second mortgage in the amount of $1.0 million (the "Second Mortgage") on the Allendale Property with TD Bank, N.A. The initial guarantors of the Second Mortgage were PCT, DomaniCell (a wholly-owned subsidiary of PCT, now known as NeoStem Family Storage, LLC), Regional Cancer Care Associates LLC and certain of its partners. The Second Mortgage had been subject to an annual financial covenant starting December 31, 2011. The Second Mortgage is for 124 months at a fixed rate of 6% for the first 64 months. The loan is callable for a certain period prior to the interest reset date. The outstanding balance was approximately $0.7 million and $0.8 million at June 30, 2014 and December 31, 2013, respectively, of which $89,000 is payable within twelve months as of June 30, 2014.

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In December 2013, the Company modified both the First Mortgage and Second Mortgage with TD Bank, N.A., whereby (i) prior debt service coverage and total debt to tangible net worth financial covenant ratios were replaced with a minimum unencumbered liquidity covenant, and (ii) prior guarantors were released (see Note 14) and replaced with NeoStem, PCT, and NeoStem Family Storage. The Company is in compliance with the new minimum unencumbered liquidity covenant.

Note 11 – Shareholders' Equity

Reverse Stock Split

On June 28, 2013, pursuant to prior shareholder authorization, the Company’s board of directors unanimously approved a 1-for-10 reverse stock split of the Company’s common stock, which the Company effected on July 16, 2013. All share and per share amounts of common stock, options and warrants in the accompanying financial statements have been restated for all periods to give retroactive effect to the reverse stock split. The shares of common stock retained a par value of $0.001 per share. Accordingly, the stockholders’ deficit reflects the reverse stock split by reclassifying from “common stock” to “additional paid-in capital” an amount equal to the par value of the decreased shares resulting from the reverse stock split.

Equity Issuances

In September 2011, the Company entered into a common stock purchase agreement (the “Initial Purchase Agreement”) with Aspire Capital Fund, LLC, an Illinois limited liability company (“Aspire Capital”), which provided that Aspire Capital was committed to purchase up to an aggregate of $20.0 million worth of shares of the Company’s common stock over the 24-month term. In August, 2012, the Initial Purchase Agreement was extended for an additional 24-month term through September 2015. During the three months ended March 31, 2014, the Company issued 0.8 million shares of Common Stock under the provisions the Initial Purchase Agreement with Aspire for gross proceeds of approximately $5.6 million. As of March 31, 2014, the full $20.0 million worth of shares of the Company's stock had been issued under the Initial Purchase Agreement.

In March 2014, the Company entered into a new common stock purchase agreement (the “Purchase Agreement”) with Aspire Capital, which provides that, subject to certain terms and conditions, Aspire Capital is committed to purchase up to an aggregate of $30.0 million worth of shares of the Company’s common stock over the 24-month term. At the Company’s discretion, it may present Aspire Capital with purchase notices from time to time to purchase the Company’s common stock, provided certain price and other requirements are met. The purchase price for the shares of stock was based upon one of two formulas set forth in the Purchase Agreement depending on the type of purchase notice the Company submits to Aspire Capital, and is based on market prices of the Company’s common stock (in the case of regular purchases) or a discount of 5% applied to volume weighted average prices (in the case of VWAP purchases), in each case as determined by parameters defined in the Purchase Agreement. As consideration for entering into the Purchase Agreement, we issued 150,000 shares of our common stock to Aspire Capital. During the six months endedJune 30, 2014, the Company issued 0.7 million shares of Common Stock under the provisions the Purchase Agreement with Aspire for gross proceeds of approximately $4.4 million.

Option Exercises

During the six months ended ended June 30, 2014, option holders exercised an aggregate of 41,136 options at exercise prices between of $5.20 and $6.20 per share for gross proceeds of approximately $0.2 million.

Warrant Exercises

During the six months ended ended June 30, 2014, warrant holders exercised an aggregate of 265,250 warrants at exercise price between $5.10 and $14.50 per share for gross proceeds of approximately $1.4 million.

Stock Options and Warrants

The following table summarizes the activity for stock options and warrants for the six months endedJune 30, 2014:

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	Stock Options							Warrants
	Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)	Aggregate Intrinsic Value (In Thousands)		Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)	Aggregate Intrinsic Value (In Thousands)
Outstanding at December 31, 2013	2,932,191		$	11.19	6.8	$	1,658.1	4,898,266		$	16.50	2.6	$	1,811.0
Changes during the period:
Granted	1,653,325		$	7.05				2,722		$	12.26
Exercised	(41,136	)	$	5.60				(265,250	)	$	5.18
Forfeited	(189,454	)	$	6.34				(100,108	)	$	70.00
Expired	(150,656	)	$	15.78				(911,674	)	$	23.97
Outstanding at June 30, 2014	4,204,270		$	9.67	7.6	$	1,657.4	3,623,956		$	13.96	2.6	$	1,080.2
Vested at June 30, 2014 or expected to vest in the future	3,891,887		$	9.86	7.4	$	1,592.8	3,623,956		$	13.96	2.6	$	1,080.2
Vested at June 30, 2014	2,533,802		$	11.16	6.5	$	1,123.2	3,611,456		$	13.98	2.6	$	1,080.2

During the six months endedJune 30, 2014 and 2013, the Company issued warrants for services as follows ($ in thousands, except share data):

	Six Months Ended June 30,
	2014		2013
Number of Common Stock Purchase Warrants Issued	—		20,407
Value of Common Stock Purchase Warrants Issued	$	—	$	71.6

Restricted Stock

During the six months endedJune 30, 2014 and 2013, the Company issued restricted stock for services as follows ($ in thousands, except share data):

	Six Months Ended June 30,
	2014		2013
Number of Restricted Stock Issued	456,709		304,402
Value of Restricted Stock Issued	$	3,389.7	$	1,858.3

The weighted average estimated fair value of restricted stock issued for services in the six months endedJune 30, 2014 and 2013 was $7.42 and $6.10 per share, respectively. The fair value of the restricted stock was determined using the Company’s closing stock price on the date of issuance. The vesting terms of restricted stock issuances are generally within one year.

Note 12 – Share-Based Compensation

Share-based Compensation

We utilize share-based compensation in the form of stock options, warrants and restricted stock.  The following table summarizes the components of share-based compensation expense for the three and six months endedJune 30, 2014 and 2013 (in thousands):

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	Three Months Ended June 30,				Six Months Ended June 30,
	2014		2013		2014		2013
Cost of goods sold	$	98.5	$	58.5	$	236.6	$	145.0
Research and development	371.6		129.8		848.4		347.1
Selling, general and administrative	1,289.6		907.4		4,568.5		2,822.1
Total share-based compensation expense	$	1,759.7	$	1,095.7	$	5,653.5	$	3,314.2

Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at June 30, 2014 were as follows (dollars in thousands):

	Stock Options		Warrants		Restricted Stock
Unrecognized compensation cost	$	6,814.9	$	33.4	$	262.9
Expected weighted-average period in years of compensation cost to be recognized	5.02		1.05		0.19

Total fair value of shares vested and the weighted average estimated fair values of shares granted for the six months endedJune 30, 2014 and 2013 were as follows (dollars in thousands):

	Stock Options				Warrants
	Six Months Ended June 30,				Six Months Ended June 30,
	2014		2013		2014		2013
Total fair value of shares vested	$	2,552.2	$	1,646.3	$	15.0	$	80.9
Weighted average estimated fair value of shares granted	$	4.92	$	4.58	$	—	$	3.51

Note 13 – Income Taxes

As of December 31, 2013, the Company had approximately $110.6 million of Federal NOLs available to offset future taxable income expiring from 2025 through 2033. In accordance with Section 382 of the Internal Revenue code, the usage of the Company’s NOLs could be limited in the event of a change in ownership. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the period when those temporary differences become deductible.  If a change of ownership did occur there would be an annual limitation on the usage of the Company’s losses which are available through 2033.

In assessing the realizability of deferred tax assets, including the net operating loss carryforwards ("NOLs"), the Company assesses the available positive and negative evidence to estimate if sufficient future taxable income will be generated to utilize its existing deferred tax assets.  Based on its assessment, the Company has provided a full valuation allowance against its net deferred tax assets as their future utilization remains uncertain at this time.

Deferred tax liabilities were $19.0 million and $4.4 million as of June 30, 2014 and December 31, 2013, and relate to the taxable temporary differences on (i) the goodwill recognized in the PCT acquisition in 2011, (ii) the in-process R&D intangible asset recognized in the Amorcyte acquisition in 2011, and (iii) the in-process R&D intangible asset recognized in the CSC acquisition in 2014. The taxable temporary difference associated with the goodwill, which is tax deductible and will be amortized over 15 years, will continue to increase the deferred tax liability balance over the amortization period, with an associated charge to the tax provision in each period. The deferred tax liabilities will only reverse when these indefinite-lived assets are sold, impaired, or reclassified from an indefinite-lived asset to a finite-lived asset.

As of June 30, 2014, management does not believe the Company has any material uncertain tax positions that would require it to measure and reflect the potential lack of sustainability of a position on audit in its financial statements. The Company will continue to evaluate its uncertain tax positions in future periods to determine if measurement and recognition in its financial statements is necessary. The Company does not believe there will be any material changes in its unrecognized tax positions over the next year.

Note 14 – Related Party Transactions

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In December 2013, the Company modified both the First Mortgage and Second Mortgage with TD Bank, N.A. (see Note 10). Pursuant to the Loan Modifications, Andrew L. Pecora, M.D., Regional Cancer Care Associates LLC (Dr. Pecora’s medical practice), and certain partners in such practice, including Dr. Pecora, have been released as guarantors of the Second Mortgage Loan, and NeoStem has become a guarantor of the Loans pursuant to a Guaranty of Payment delivered by NeoStem to the Lender. Dr. Pecora, currently serves as a NeoStem director, NeoStem’s Chief Visionary Officer, PCT’s Chief Medical Officer and Amorcyte’s Chief Scientific Officer.

Note 15 – Commitments and Contingencies

Lease Commitments

The Company leases offices, of which certain have escalation clauses and renewal options, and also leases equipment under certain noncancelable operating leases that expire from time to time through 2018. In January 2014, the Company signed a new lease for additional space at its current executive offices at 420 Lexington Avenue, New York, NY 10170. The new lease is believed to provide sufficient space for the near future and shall extend through 2018. This property is used as the Company's corporate headquarters. In connection with the acquisition of CSC on May 8, 2014, the Company assumed a facility lease in Irvine, California, with a termination at the end of 2017.

A summary of future minimum rental payments required under operating leases that have initial or remaining terms in excess of one year as of June 30, 2014 are as follows (in thousands):  

Years ended	Operating Leases
2014	$	675.3
2015	1,160.5
2016	997.9
2017	697.8
2018	5.9
Total minimum lease payments	$	3,537.4

Expense incurred under operating leases was approximately $0.3 million and $0.3 million for the three months endedJune 30, 2014 and 2013, respectively. Expense incurred under operating leases was approximately $0.5 million and $0.6 million for the six months endedJune 30, 2014 and 2013, respectively.

Contingencies

Under license agreements with third parties the Company is typically required to pay maintenance fees, make milestone payments and/or pay other fees and expenses and pay royalties upon commercialization of products. The Company also sponsors research at various academic institutions, which research agreements generally provide us with an option to license new technology discovered during the course of the sponsored research.

ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS.

The following Management’s Discussion and Analysis of Financial Condition and Results of Operations contains forward-looking statements that involve risks and uncertainties. Our actual results could differ materially from those anticipated in these forward-looking statements as a result of various factors, including those set forth under “Cautionary Note Regarding Forward-Looking Statements” herein and under “Risk Factors” in our annual report on Form 10-K for the year ended December 31, 2013. The following discussion should be read in conjunction with our consolidated financial statements and related notes thereto included elsewhere in this quarterly report and in our annual report on Form 10-K for the year ended December 31, 2013.

Overview

NeoStem, Inc. (“we,” “NeoStem” or the “Company”) is a leader in the emerging cellular therapy industry. We are pursuing the preservation and enhancement of human health globally through the development of cell based therapeutics that prevent, treat or cure disease. We have multiple cell therapy platforms that work to address the pathology of disease using a person's own cells to amplify the body's natural repair mechanisms including enhancing the destruction of cancer initiating cells, repairing and

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replacing damaged or aged tissue, cells and organs and restoring their normal function. We believe that cell therapy will play a large role in changing the natural history of diseases as more breakthrough therapies are developed, ultimately lessening the overall burden of disease on patients and their families as well as the economic burden that these diseases impose upon modern society.

Our business includes the development of novel proprietary cell therapy products, as well as a revenue-generating contract development and manufacturing service business that we leverage for the development of our therapeutics while providing service to other companies in the cell therapy industry. The combination of our own therapeutic development business and a revenue-generating service provider business provides the Company with unique capabilities for cost effective in-house product development and immediate revenue and future cash flow to help underwrite our internal development programs. This business model enables the Company to be opportunistic in growing its pipeline as evidenced by the Company's acquisition in May 2014 of California Stem Cell, Inc. ("CSC"), a cell biotechnology corporation that is developing cellular immunotherapies for cancer, an area we view to be one of the most promising sub-sectors in biotechnology. The lead product candidate in its immunotherapy pipeline is NBS20, also referred to as DC/TC (dendritic cell/tumor cell), and is targeting malignant melanoma initiating cells. This immunotherapy designed to treat Stage IV or recurrent Stage III metastatic melanoma, which has been granted fast track and orphan designation by the Food and Drug Administration ("FDA"), also has a Phase 3 protocol that is the subject of a Special Protocol Assessment (SPA). The SPA indicates that the FDA is in agreement with the design, clinical endpoints, and planned clinical analyses of the Phase 3 trial that would serve as the basis for a Biologics License Application ("BLA") that would be filed with the FDA requesting marketing approval of this therapeutic candidate. This protocol calls for enrolling 250 evaluable patients and is expected to be initiated later in 2014. We are evaluating other clinical indications into which we may advance this program, including liver, ovarian and lung cancers.

We are also currently developing therapies to address ischemia utilizing CD34 cells. Ischemia occurs when the supply of oxygenated blood in the body is restricted. We seek to reverse this restriction through the development and formation of new blood vessels. NBS10, also referred to as AMR-001, is our most clinically advanced product candidate in our ischemic repair program and is being developed to treat damaged heart muscle following an acute myocardial infarction (heart attack) ("AMI"). In December 2013, the Company completed enrollment in its PreSERVE AMI study. PreSERVE AMI is a randomized, double-blinded, placebo-controlled Phase 2 clinical trial testing NBS10, an autologous (donor and recipient are the same) adult stem cell product for the treatment of patients with left ventricular dysfunction following acute ST segment elevation myocardial infarction (STEMI). The last patient in the trial was infused in December 2013 and the last patient six-month follow-up occurred in June 2014. Once the primary end point six-month data is collected, the data set will be locked and analysis will begin.   An abstract for the PreSERVE AMI study has been accepted for presentation at the American Heart Association's Scientific Sessions being held November 15-19, 2014 although we anticipate results of the study will be released earlier. If approved by the FDA and/or other worldwide regulatory agencies following successful completion of further trials, NBS10 would address a significant medical need for which there is currently no effective treatment, potentially improving longevity and quality of life for those suffering a STEMI, and positioning the Company to capture a meaningful share of this worldwide market. We are evaluating other clinical indications into which we may advance this program, including traumatic brain injury ("TBI"), congestive heart failure ("CHF") and critical limb ischemia ("CLI").

Another platform technology we are developing utilizes T Regulatory Cells ("Tregs") to treat diseases caused by imbalances in an individual's immune system.  Collaborating with the University of California, San Francisco, we are utilizing the technology platform of our majority-owned subsidiary, Athelos Corporation ("Athelos"), to restore immune balance by enhancing Treg cell number and function.  Tregs are a natural part of the human immune system and regulate the activity of T effector cells, the cells that are responsible for protecting the body from viruses and other foreign antigen exposure. When Tregs function properly, only harmful foreign materials are attacked by T effector cells. In autoimmune disease it is thought that deficient Treg activity permits the T effector cells to attack the body's own tissues, while in allergic diseases, like asthma, it is thought that the immune system overreacts to harmless foreign substances. We plan to initiate in 2014, subject to review and approval of the protocols by the appropriate regulatory authorities, a Phase 2 study of NBS03D, a Treg based therapeutic, in the treatment of type 1 diabetes, and a Phase 1 study of NBS03A, a Treg based therapeutic, in Canada in support of our steroid resistant asthma development program.

Pre-clinical assets include our VSEL ^TM (Very Small Embryonic Like) Technology regenerative medicine platform. Regenerative medicine holds the promise of improving clinical outcomes and reducing overall  healthcare costs.  We are working on a Department of Defense funded study of VSELs^TM for the treatment of chronic wounds. Other preclinical work with VSELs^TM includes exploring macular degeneration as a target indication.

Progenitor Cell Therapy, LLC ("PCT") is a contract manufacturer in the cellular therapy industry that generates revenue. This wholly owned subsidiary, which we acquired in 2011, is an industry leader in providing high quality manufacturing capabilities and support to developers of cell-based therapies to enable them to improve efficiencies and profitability and reduce the capital investment required for their own development activities. Since its inception more than 15 years ago, PCT has provided pre-

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clinical and clinical current Good Manufacturing Practice (“cGMP”) development and manufacturing services to more than 100 clients. PCT has experience advancing regenerative medicine product candidates from product inception through rigorous quality standards all the way through to human testing, BLA filing and FDA product approval. PCT's core competencies in the cellular therapy industry include manufacturing of cell therapy-based products, engineering and innovation services, product and process development, cell and tissue processing, regulatory support, storage, distribution and delivery and consulting services. PCT has two cGMP, state-of-the art cell therapy research, development, and manufacturing facilities in New Jersey and California, serving the cell therapy community with integrated and regulatory compliant distribution capabilities. The Company is pursuing commercial expansion of our manufacturing operations both in the U.S. and internationally. Additionally, with our acquisition of CSC in Irvine, California, we are now in a position to leverage NeoStem Oncology's expertise in immunotherapy and advance our platform technology, as well as the technologies of PCT's client base.

Strategic acquisitions have been the cornerstone of NeoStem’s growth and have been selected in order to provide value to stockholders by taking advantage of the infrastructure we have created which includes strong development, regulatory and manufacturing expertise. By adding NBS20, our DC/TC product candidate and a late stage novel proprietary cancer cell therapy into our pipeline, we look to further advance towards our goal of delivering transformative cell based therapies to the market to help patients suffering from life-threatening medical conditions. Coupled with our strong manufacturing capability, we believe the stage is set for us to realize meaningful clinical development and manufacturing efficiencies, further positioning NeoStem to lead the cell therapy industry.

Results of Operations

Three and Six Months EndedJune 30, 2014 Compared to Three and Six Months EndedJune 30, 2013

Net loss for the three months endedJune 30, 2014 was approximately $12.8 million compared to $8.6 million for the three months endedJune 30, 2013. Net loss for the six months endedJune 30, 2014 was approximately $26.6 million compared to $17.5 million for the six months endedJune 30, 2013.

Revenues

For the three months endedJune 30, 2014, total revenues were approximately $4.5 million compared to $4.4 million for the three months endedJune 30, 2013, representing an increase of $0.1 million, or 3%. Revenues were comprised of the following (in thousands):

	Three Months Ended June 30,
	2014		2013
Clinical Services	$	2,493.9	$	3,114.1
Clinical Services Reimbursables	1,099.3		423.6
Processing and Storage Services	895.7		821.7
	$	4,488.9	$	4,359.4

• Clinical Services, representing process development and clinical manufacturing services provided by PCT to its various clients, were approximately $2.5 million for the three months endedJune 30, 2014 compared to $3.1 million for the three months endedJune 30, 2013, representing a decrease of approximately $0.6 million or 20%. The decrease was primarily due to $0.6 million of lower process development revenue, such revenue being recognized on a "completed contract" basis. Clinical manufacturing revenue (which is recognized as services are rendered) was unchanged. Overall, there were approximately 50% more Clinical Services active clients as of June 30, 2014 compared to June 30, 2013.

◦ Process Development Revenue - Process development revenues were approximately $1.0 million for the three months endedJune 30, 2014 compared to $1.7 million for the three months endedJune 30, 2013. In accordance with our revenue recognition policy, process development revenue is recognized upon contract completion (i.e., when the services under a particular contract are completed). Although process development revenues decreased for the three months endedJune 30, 2014 compared with the three months endedJune 30, 2013, the number of active process development contracts was approximately double in the current year period, resulting in approximately $2.1 million of deferred process development revenue as of June 30, 2014. This revenue will be recognized in future periods upon completion of those contracts. Process development revenue will continue to fluctuate from period to period as a result of our process development revenue recognition policy.

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◦ Clinical Manufacturing Revenue - Clinical manufacturing revenues were approximately $1.4 million for both the three months endedJune 30, 2014 and 2013.

• Clinical Services Reimbursables, representing reimbursement of expenses for certain consumables incurred on behalf of our clinical service revenue clients, were approximately $1.1 million for the three months endedJune 30, 2014 compared to $0.4 million for the three months endedJune 30, 2013, representing an increase of approximately $0.7 million or 159%. Generally, clinical services reimbursables correlate with clinical services revenues. However, differences in the cost of supplies to be reimbursed can vary greatly from contract to contract based on the cost of supplies needed for each client's manufacturing and development process, and may impact this correlation. In addition, our terms for billing reimbursable expenses do not include a significant mark up in the acquisition cost of such consumables, and as a result, changes in this revenue category have little impact on our gross profit and net loss.

• Processing and Storage Services, primarily representing revenues from our oncology stem cell processing, cord blood, and adult stem cell processing and banking activities, were approximately $0.9 million for the three months endedJune 30, 2014 compared to $0.8 million for the three months endedJune 30, 2013, representing an increase of approximately $0.1 million or 9%.

For the six months endedJune 30, 2014, total revenues were approximately $8.5 million compared to $6.9 million for the six months endedJune 30, 2013, representing an increase of $1.7 million, or 24%. Revenues were comprised of the following (in thousands):

	Six Months Ended June 30,
	2014		2013
Clinical Services	$	5,060.9	$	4,479.7
Clinical Services Reimbursables	1,847.3		786.4
Processing and Storage Services	1,636.3		1,617.2
	$	8,544.5	$	6,883.3

• Clinical Services were approximately $5.1 million for the six months endedJune 30, 2014 compared to $4.5 million for the six months endedJune 30, 2013, representing an increase of approximately $0.6 million or 13%. The increase was primarily due to $0.6 million of higher clinical manufacturing revenue, whereas process development revenue was unchanged. Overall, there were approximately 50% more Clinical Services active clients as of June 30, 2014 compared to June 30, 2013.

◦ Process Development Revenue - Process development revenues were approximately $1.8 million for both the six months endedJune 30, 2014 and 2013. Although process development revenues were unchanged for the six months endedJune 30, 2014 compared with the six months endedJune 30, 2013, the number of active process development contracts was approximately double in the current year period, resulting in approximately $2.1 million of deferred process development revenue as of June 30, 2014. Process development revenue will continue to fluctuate from period to period as a result of our process development revenue recognition policy.

◦ Clinical Manufacturing Revenue - Clinical manufacturing revenues were approximately $3.2 million for the six months endedJune 30, 2014, compared to $2.6 million for the six months endedJune 30, 2013. The increase is primarily due to an increase in the number of patients our customers have enrolled and treated in clinical trials.

• Clinical Services Reimbursables were approximately $1.8 million for the six months endedJune 30, 2014 compared to $0.8 million for the six months endedJune 30, 2013, representing an increase of approximately $1.1 million or 135%. Generally, clinical services reimbursables correlate with clinical services revenues. However, differences in the cost of supplies to be reimbursed can vary greatly from contract to contract based on the cost of supplies needed for each client's manufacturing and development process, and may impact this correlation. In addition, our terms for billing reimbursable expenses do not include a significant mark up in the acquisition cost of such consumables, and as a result, changes in this revenue category have little impact on our gross profit and net loss.

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• Processing and Storage Services were approximately $1.6 million for both the six months endedJune 30, 2014 and 2013.

Operating Costs and Expenses of Revenues

     For the three months endedJune 30, 2014, operating expenses totaled $16.9 million compared to $12.5 million for the three months endedJune 30, 2013, representing an increase of $4.4 million or 35%. Operating expenses were comprised of the following:

• Cost of revenues were approximately $3.7 million the three months endedJune 30, 2014 compared to $4.2 million for the three months endedJune 30, 2013, representing a decrease of $0.6 million or 13%. Overall, gross profit for the three months endedJune 30, 2014 was $0.8 million or 18%, compared to gross profit for the three months endedJune 30, 2013 of $0.1 million or 3%. Gross profit percentages generally will increase as Clinical Service revenue increases. However, gross profit percentages will also fluctuate from period to period due to the mix of service and reimbursable revenues and costs, as well as the timing of our revenue recognition under our revenue recognition policy.

• Research and development expenses were approximately $5.8 million for the three months endedJune 30, 2014 compared to $4.0 million for the three months endedJune 30, 2013, representing an increase of approximately $1.8 million, or 46%. Research and development expenses associated with the targeted cancer immunotherapy program, and specifically efforts associated with the planned initiation of the Phase 3 clinical trial for our lead product candidate NBS20, also referred to as DC/TC, targeting malignant melanoma initiating cells, were $2.0 million for the three months endedJune 30, 2014. The oncology platform was acquired in the CSC merger on May 8, 2014. Research and development expenses related to NBS10, also referred to as AMR-001, including expenses associated with our Phase 2 clinical trial, decreased by approximately $1.6 million for the three months endedJune 30, 2014 compared to the prior year period. The Phase 2 clinical trial completed enrollment in the fourth quarter of 2013. Research and development expenses associated with our immune modulation program utilizing T regulatory cells ("Tregs") increased by approximately $1.4 million, and was primarily due to our efforts to develop Tregs for the treatment of type 1 diabetes, steroid resistant asthma, and organ transplant rejection. Within the immune modulation program, we continue to focus efforts on initiating a Phase 2 study of NBS03D in type 1 diabetes in 2014, and a Phase 1 study of NBS03A in Canada in support of a steroid resistant asthma indication in 2014, subject to review and approval of the protocols by the appropriate regulatory authorities. Research and development associated with engineering and innovation initiatives at PCT to improve scale up, automation, and integration capabilities also increased marginally during the current quarter compared to the prior year quarter. Equity-based compensation included in research and development expenses for the three months endedJune 30, 2014 and June 30, 2013 were approximately $0.4 million and $0.1 million, respectively.

• Selling, general and administrative expenses were approximately $7.4 million for the three months endedJune 30, 2014 compared to $4.3 million for the three months endedJune 30, 2013, representing an increase of approximately $3.1 million, or 72%. Equity-based compensation included in selling, general and administrative expenses for the three months endedJune 30, 2014 was approximately $1.3 million, compared to approximately $0.9 million for the three months endedJune 30, 2013, representing an increase of $0.4 million. The increase in equity-based compensation is due to the broader use of equity-based compensation during the current quarter, as well as changes in option vesting provisions initiated in 2013, impacting the timing of equity-based compensation expense recognition. Equity-based compensation expense will continue to fluctuate in future quarters as equity-linked instruments are used to compensate employees, consultants and other service providers. Non-equity-based general and administrative expenses for the three months endedJune 30, 2014 were approximately $6.1 million, compared to approximately $3.4 million for the three months endedJune 30, 2013, representing an increase of $2.7 million. The increase was related to higher strategic and corporate development activities, including efforts associated with the acquisition of CSC on May 8, 2014, expenses associated with the additional CSC operating activities since the acquisition date, and increased corporate infrastructure to support our expanded clinical activities.

     For the six months endedJune 30, 2014, operating expenses totaled $34.5 million compared to $23.9 million for the six months endedJune 30, 2013, representing an increase of $10.6 million or 44%. Operating expenses were comprised of the following:

• Cost of revenues were approximately $7.5 million for the six months endedJune 30, 2014 compared to $6.6 million for the six months endedJune 30, 2013, representing an increase of $0.9 million or 13%. Overall, gross profit for the six months endedJune 30, 2014 was $1.0 million or 12%, compared to gross profit for the six months endedJune 30, 2013

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of $0.3 million or 4%. Gross profit percentages generally will increase as Clinical Service revenue increases. However, gross profit percentages will also fluctuate from period to period due to the mix of service and reimbursable revenues and costs, as well as the timing of our revenue recognition under our revenue recognition policy.

• Research and development expenses were approximately $10.6 million for the six months endedJune 30, 2014 compared to $7.1 million for the six months endedJune 30, 2013, representing an increase of approximately $3.5 million, or 48%. Research and development expenses associated with the targeted caner immunotherapy program, and specifically efforts associated with the planned initiation of the Phase 3 clinical trial for our lead product NBS20 targeting malignant melanoma initiating cells, were $2.0 million for the six months endedJune 30, 2014. The oncology platform was acquired in the CSC merger on May 8, 2014. Research and development expenses related to NBS10, also referred to as AMR-001, including expenses associated with our Phase 2 clinical trial, decreased by approximately $1.5 million for the six months endedJune 30, 2014 compared to the prior year period. The Phase 2 clinical trial completed enrollment in the fourth quarter of 2013. Research and development expenses associated with our immune modulation program that utilizes T regs increased by approximately $2.4 million, and was primarily due to our efforts to develop Tregs for the treatment of type 1 diabetes, steroid resistant asthma, and organ transplant rejection. Within the immune modulation program, we continue to focus efforts on initiating a Phase 2 study of NBS03D in type 1 diabetes in 2014, and a Phase 1 study of NBS03A in Canada in support of a steroid resistant asthma indication in 2014 subject to review and approval of the protocols by the appropriate regulatory authorities. Research and development associated with engineering and innovation initiatives at PCT to improve scale up, automation, and integration capabilities also increased during the current quarter compared to the prior year quarter. Equity-based compensation included in research and development expenses for the six months endedJune 30, 2014 and June 30, 2013 were approximately $0.8 million and $0.3 million, respectively.

• Selling, general and administrative expenses were approximately $16.4 million for the six months endedJune 30, 2014 compared to $10.1 million for the six months endedJune 30, 2013, representing an increase of approximately $6.3 million, or 62%. Equity-based compensation included in selling, general and administrative expenses for the six months endedJune 30, 2014 was approximately $4.6 million, compared to approximately $2.8 million for the six months endedJune 30, 2013, representing an increase of $1.8 million. The increase in equity-based compensation is due to the broader use of equity-based compensation during the current year, as well as changes in option vesting provisions initiated in 2013, impacting the timing of equity-based compensation expense recognition. Equity-based compensation expense will continue to fluctuate in future quarters as equity-linked instruments are used to compensate employees, consultants and other service providers. Non-equity-based general and administrative expenses for the six months endedJune 30, 2014 were approximately $11.8 million, compared to approximately $7.2 million for the six months endedJune 30, 2013, representing an increase of $4.6 million. The increase was related to higher strategic and corporate development activities, including efforts associated with the acquisition of CSC on May 8, 2014, expenses associated with the additional CSC operating activities since the acquisition date, and increased corporate infrastructure to support our expanded clinical activities.

Historically, to minimize our use of cash, we have used a variety of equity and equity-linked instruments to compensate employees, consultants and other service providers. The use of these instruments has resulted in charges to the results of operations, which has been significant in the past. In general, these equity and equity-linked instruments are used to pay for employee and consultant compensation, director fees, marketing services, investor relations and other activities. For example, in August 2014, the Compensation Committee granted equity awards to certain employees for the successful completion of the CSC acquisition in May 2014. These awards, comprised of 112,244 shares of the Company's common stock and options to purchase 300,000 shares of the Company's common stock, were fully vested upon grant. The equity awards, along with the withholding taxes associated with the common stock awards which are being paid by the Company, are expected to result in compensation charges in the third quarter of 2014 of approximately $2.4 million.

Other Income (Expense)

Other expense, net for the three and six months endedJune 30, 2014 was approximately $186,000 and $375,000, respectively, and primarily relates to the increase in the estimated fair value of our contingent consideration liability associated with potential earn out payments on the net sales of our product candidate NBS10 (in the event of and following the date of first commercial sale of NBS10). Other income, net, for the three and six months endedJune 30, 2013 was approximately $58,000 and $69,000, respectively, and primarily relates to the revaluation of derivative liabilities.

For the three and six months endedJune 30, 2014 interest expense was $106,000 and $200,000, respectively, compared with $66,000 and $109,000, respectively, for the three and six months endedJune 30, 2013.

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Provision for Income Taxes

The provision for income taxes for the three and six months endedJune 30, 2014 relate to the taxable temporary differences on the goodwill recognized in the PCT acquisition in 2011, which is being amortized over 15 years for tax purposes. A tax provision will continue to be recognized each period over the amortization period, and will only reverse when the goodwill is eliminated through a sale, impairment, or reclassification from an indefinite-lived asset to a finite-lived asset.

Noncontrolling Interests

In March 2011, we acquired rights to use patents under licenses from Becton, Dickinson and Company ("BD") in exchange for a 19.9% interest in our Athelos subsidiary. Pursuant to the Stock Purchase Agreement signed in March 2011, BD's ownership will be diluted based on new investment in Athelos (subject to certain anti-dilution provisions). As of June 30, 2014, BD's ownership interest in Athelos was decreased to 10.0%, and our ownership increased to 90.0%. For the three and six months endedJune 30, 2014, BD’s share of Athelos’ net loss totaled approximately $0.2 million and $0.3 million, respectively. For the three and six months endedJune 30, 2013, BD’s share of Athelos’ net loss totaled approximately $0.1 million and $0.1 million, respectively.

Analysis of Liquidity and Capital Resources

At June 30, 2014 we had a cash and cash equivalents and marketable securities of approximately $33.8 million, working capital of approximately $28.9 million, and stockholders’ equity of approximately $78.0 million.

During the six months endedJune 30, 2014, we met our immediate cash requirements through revenue generated from our PCT operations, existing cash balances, the issuance of common stock under our purchase agreement with Aspire, and warrant and option exercises. Additionally, we used equity and equity-linked instruments to pay for services and compensation.

Net cash provided by or used in operating, investing and financing activities from continuing operations were as follows (in thousands): 

	Six Months Ended June 30,
	2014			2013
Net cash used in operating activities	$	(22,506.2	)	$	(13,125.8	)
Net cash used in investing activities	(3,308.2		)	(268.5		)
Net cash provided by financing activities	12,545.8			14,379.3

Operating Activities

Our cash used in operating activities in the six months endedJune 30, 2014 totaled approximately $22.5 million, which is the sum of (i) our net loss of $26.6 million, and adjusted for non-cash expenses totaling $7.1 million (which includes adjustments for equity-based compensation and depreciation and amortization), and (ii) changes in operating assets and liabilities providing approximately $3.0 million.

Our cash used in operating activities in the six months endedJune 30, 2013 totaled approximately $13.1 million, which is the sum of (i) our net loss of $17.5 million, and adjusted for non-cash expenses totaling $4.5 million (which includes adjustments for equity-based compensation and depreciation and amortization), and (ii) changes in operating assets and liabilities providing approximately $0.2 million.

Investing Activities

During the six months endedJune 30, 2014, we spent approximately $2.4 million for property and equipment, and invested approximately $0.9 million in marketable securities. During the six months endedJune 30, 2013, we spent approximately $0.3 million for property and equipment.

Financing Activities

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During the six months endedJune 30, 2014, our financing activities consisted of the following: 

• We raised gross proceeds of approximately $10.1 million through the issuance of approximately 1.5 million shares of Common Stock under the provisions of our equity line of credit with Aspire.

• We raised approximately $0.2 million from the exercise of 41,136 options.

• We raised approximately $1.4 million from the exercise of 265,250 warrants.

• We received proceeds of $1.3 million from the issuance of notes payable relating to certain insurance policies and equipment financings, less repayments of $0.4 million.

During the six months endedJune 30, 2013, our financing activities consisted of the following: 

• We raised $11.5 million (or $10.5 million in net proceeds after deducting underwriting discounts and commissions and offering expenses) through an underwritten offering of 2.3 million shares of our common stock at a public offering price of $5.00 per share.

• We raised gross proceeds of approximately $3.8 million through the issuance of 654,300 shares of Common Stock under the provisions of our equity line of credit with Aspire.

• We raised approximately $0.1 million from the exercise of approximately 20,800 warrants.

Liquidity and Capital Requirements Outlook

We anticipate requiring additional capital in order to fund the development of cell therapy product candidates, particularly in our Targeted Immunotherapy Program, CD34 Cell Program and T Regulatory Cell Program, as well as engage in strategic transactions. The most significant funding needs are anticipated to be in connection with the conduct of our Intus Phase 3 clinical trial of NBS20 for stage IV and recurrent stage III melanoma which is expected to be initiated in 2014 and cost approximately $25 million, and other costs related to the cancer immunotherapy operations acquired from CSC in May 2014. The acquisition of CSC could result in our re-prioritizing the timing of the initiation of certain of our other earlier stage clinical trials. We also anticipate requiring additional capital to grow the PCT business, including implementing additional automation capabilities and pursuing plans to establish commercial capacity and expand internationally. Additionally, we recently completed expansion in the Allendale, New Jersey facility adding laboratory, clean room suites and support facilities, and completed expansion in the Mountain View, California facility adding manufacturing capacity with additional clean rooms, laboratory space and support facilities.

To meet our short and long term liquidity needs, we currently expect to use existing cash balances, our revenue generating activities, and a variety of other means. Those other means include the continued use of a common stock purchase agreement with Aspire (the "Aspire Agreement"). We entered into a new $30 million common stock purchase agreement with Aspire in March 2014, of which we had $25.6 million remaining available at June 30, 2014. Other sources of liquidity could include potential issuances of debt or equity securities in public or private financings, additional warrant exercises, option exercises, and/or sale of assets. In addition, we will continue to seek as appropriate grants for scientific and clinical studies from the National Institutes of Health, Department of Defense, and other governmental agencies and foundations, but there can be no assurance that we will be successful in qualifying for or obtaining such grants. Our history of operating losses and liquidity challenges, may make it difficult for us to raise capital on acceptable terms or at all. The demand for the equity and debt of small cap biopharmaceutical companies like ours is dependent upon many factors, including the general state of the financial markets. During times of extreme market volatility, capital may not be available on favorable terms, if at all. Our inability to obtain such additional capital could materially and adversely affect our business operations. We believe that our current cash balances and revenue generating activities, along with access to the Aspire Agreement, will be sufficient to fund the business, as now operated, into 2015.

While we continue to seek capital through a number of means, there can be no assurance that additional financing will be available on acceptable terms, if at all, and our negotiating position in capital generating efforts may worsen as existing resources are used. Additional equity financing may be dilutive to our stockholders; debt financing, if available, may involve significant cash payment obligations and covenants that restrict our ability to operate as a business, our stock price may not reach levels necessary to induce option or warrant exercises, and asset sales may not be possible on terms we consider acceptable. If we are unable to raise the funds necessary to meet our long-term liquidity needs, we may have to delay or discontinue the acquisition and development of cell therapies, and/or the expansion of our business or raise funds on terms that we currently consider unfavorable.

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Commitments and Contingencies

The following table summarizes our obligations to make future payments under current contracts as of June 30, 2014 (in thousands):

	Total		Less than 1 Year		1-3 Years		3-5 Years		More than 5 Years
Contractual Obligations
Mortgages Payable	$	3,131.3	$	219	$	475.2	$	2,221.2	$	215.9
Notes Payable	1,809.9		794.2		1,015.7		—		—
Operating Lease Obligations	3,537.4		1,341.3		1,991.8		204.3		—
	$	8,478.6	$	2,354.5	$	3,482.7	$	2,425.5	$	215.9

Under our agreements with external clinical research organizations (“CRO's”), we will incur expenses relating to our clinical trials for our therapeutic product candidates in development. The timing and amount of these expenses are based on performance, and therefore, we cannot reasonably estimate the timing of these payments.

SEASONALITY

NeoStem does not believe that its operations are seasonal in nature.

OFF-BALANCE SHEET ARRANGEMENTS

NeoStem does not have any off-balance sheet arrangements.

CRITICAL ACCOUNTING POLICIES AND ESTIMATES

There have been no material changes in our critical accounting policies and estimates during the six months endedJune 30, 2014, compared to those reported in our 2013 Form 10-K.

ITEM 3.  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK.

Market risk is the risk of change in fair value of a financial instrument due to changes in interest rates, equity prices, creditworthiness, financing, exchange rates or other factors. Our primary market risk exposure relates to changes in interest rates. Our earnings and cash flows are subject to fluctuations due to changes in interest rates, principally in connection with our investments in marketable securities, which consist primarily of short-term money market funds and municipal debt securities. However, as of June 30, 2014, we do not believe we are materially exposed to changes in interest rates given the short-term duration of the securities. Additionally, our mortgage, representing our largest component of debt, has a fixed interest rate until 2017, and is not subject to interest rate exposure. As a result, we do not believe we have material exposure to market risk related to interest rate changes as of June 30, 2014.

ITEM 4.  CONTROLS AND PROCEDURES.  

(a)  Disclosure Controls and Procedures

Disclosure controls and procedures are the Company’s controls and other procedures that are designed to ensure that information required to be disclosed in the reports that the Company files or submits under the Securities Exchange Act of 1934, as amended (the “Exchange Act”) is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission’s rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed in the reports that the Company files under the Exchange Act is accumulated and communicated to management, including the Chief Executive Officer and Chief Financial Officer, as appropriate, to allow timely decisions regarding required disclosure. In designing and evaluating the disclosure controls and procedures, management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives. Due to the inherent limitations of control systems, not all misstatements may be detected. These inherent limitations include the realities that judgments in decision-making can be faulty and that breakdowns can occur because of a simple error or mistake. Additionally, controls can be circumvented by the individual acts of some persons, by collusion of two or more people, or by management override of the control. Controls and procedures can only provide reasonable, not absolute, assurance that the above objectives have been met.

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As of June 30, 2014, the Company carried out an evaluation, with the participation of the Company’s management, including the Company’s Chief Executive Officer and Chief Financial Officer, of the effectiveness of the Company’s disclosure controls and procedures pursuant to Rule 13a-15(e) and 15d-15(e) of the Exchange Act. Based on that evaluation, the Company’s Chief Executive Officer and Chief Financial Officer concluded that the Company’s disclosure controls and procedures were effective, at the reasonable assurance level, in ensuring that information required to be disclosed by the Company in the reports that it files or submits under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the SEC’s rules and forms and is accumulated and communicated to management, including the Chief Executive Officer and Chief Financial Officer, as appropriate to allow timely decisions regarding required disclosure.

(b)  Changes in Internal Control over Financial Reporting

There have been no changes in the Company’s internal controls over financial reporting, as such term is defined in Exchange Act Rule 13a-15, that occurred during the Company’s last quarter to which this report relates that have materially affected, or are reasonably likely to materially affect, the Company’s internal control over financial reporting.

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PART II

OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS.

There are no material changes to the disclosures provided in the Company’s Annual Report on Form 10-K for the year ended December 31, 2013, except that a final order was entered in the matter discussed therein in June 2014 approving the settlement (for which a preliminary approval order has been entered in 2012) and awarding fees to plaintiff’s counsel.

ITEM 1A. RISK FACTORS

There have been no material changes from the risk factors previously disclosed in the Company's Annual Report on Form 10-K for the year ended December 31, 2013 and Current Report on Form 8-K filed on May 8, 2014. See the risk factors set forth in the Company's Annual Report on Form 10-K for the year ended December 31, 2013 under the caption "Item 1 A - Risk Factors." Additionally, the Company’s acquisition of California Stem Cell, Inc. (“CSC Acquisition”) and the ongoing operations associated with this new business will subject the Company to additional risks.  Our Current Report on Form 8-K filed on May 8, 2014 reporting the closing of the CSC Acquisition contains a discussion of the risk factors related to the CSC Acquisition and our new Targeted Immunotherapy Program. 

ITEM 2.  UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

As previously disclosed, and as follows:

The Company has agreed to issue equity to certain consultants for services. Effective June 20, 2014 pursuant to a three month agreement for consulting services in investor relations and other specified matters, the Company agreed to issue to a consultant 24,000 shares of the Company's restricted common stock, vesting as to 6,000 shares on the commencement date and as to 6,000 shares the first day of each month throughout the term of the agreement. Effective July 1, 2014, pursuant to a six month extension for consulting services in information technology and accounting systems, the Company agreed to issue to a consultant, 6,600 shares of the Company's restricted common stock, vesting ratably throughout the term of the agreement on a monthly basis. Also effective July 1, 2014, pursuant to a six month extension for consulting services in accounting systems and regulatory compliance, the Company agreed to issue to a consultant, 4,400 shares of the Company's restricted common stock vesting ratably throughout the term of the agreement on a monthly basis. Effective August 1, 2014, pursuant to a six month agreement for consulting services in media, marketing, advertising, and other specified matters, the Company agreed to issue to a consultant 27,000 shares of the Company's restricted common stock, vesting ratably throughout the term of the agreement.  Effective August 6, 2014, pursuant to a six month consulting agreement for consulting services in corporate finance, investor communications, investor relations and other specified matters, the Company agreed to issue to a consultant 50,000 shares of the Company's restricted common stock, vesting as to 25,000 shares on execution and as to 25,000 shares on November 1, 2014. Effective August 7, 2014, pursuant to a seven month agreement for consulting services in investor relations and other specified matters, the Company agreed to issue to a consultant 36,000 shares of the Company's restricted common stock vesting ratably throughout the term of the agreement.

The offer and sale by the Company of the securities described above were made in reliance upon the exemption from registration provided by Section 4(a)(2) of the Securities Act of 1933, as amended (the “Securities Act”), for transactions by an issuer not involving a public offering. The offer and sale of such securities were made without general solicitation or advertising to “accredited investors” as such term is defined in Rule 501(a) of Regulation D promulgated under the Securities Act and/or pursuant to Regulation D or Regulation S, each promulgated under the Securities Act and may not be resold in the United States or to U.S. persons unless registered under the Securities Act or pursuant to an exemption from registration under the Securities Act.

ITEM 3.  DEFAULTS UPON SENIOR SECURITIES

Not applicable.

ITEM 4. MINE SAFTEY DISCLOSURES.

Not applicable.

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ITEM 5. OTHER INFORMATION.

None.    

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ITEM 6. EXHIBITS

The exhibits to this Form 10-Q are listed in the Exhibit Index included elsewhere herein.

NEOSTEM, INC.

FORM 10Q

Exhibit Index

2.1	Agreement and Plan of Merger, dated as of April 11, 2014, by and among NeoStem, Inc., California Stem Cell, Inc., NBS Acquisition Company I, Inc., NBS Acquisition Company II, LLC, and Jason Livingston, solely in his capacity as CSC stockholder representative (incorporated by reference to Exhibit 4.18 to the Company's Current Report on Form 8-K filed on April 14, 2014)
10.1	Common Stock Purchase Agreement, dated as of March 11, 2014, by and between NeoStem, Inc. and Aspire Capital Fund, LLC (incorporated by reference to Exhibit 10.10 to the Company's Annual Report on Form 10-K filed on March 13, 2014)
10.2	Escrow Agreement, dated as of May 8, 2014, by and among NeoStem, Inc., California Stem Cell, Inc., Fortis Advisors, LLC solely in its capacity as the CSC Representative, and Continental Stock Transfer & Trust Company (incorporated by reference to Exhibit 10.1 to the Company's Current Report on Form 8-K filed on May 8, 2014)
10.3	Employment Agreement dated April 11, 2014 between NeoStem, Inc. and Hans Keirstead, PhD*
10.4	Offer Letter of Employment dated May 2, 2014 between NeoStem, Inc. and Dr. Robert Dillman*
10.5	Letter Agreement dated August 4, 2014, between NeoStem, Inc. and Catherine M. Vaczy, Esq.*
31.1	Certification of Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002*
31.2	Certification of Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002*
32.1	Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002**
32.2	Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002**
101.INS	XBRL Instance Document***
101.SCH	XBRL Taxonomy Extension Schema***
101.CAL	XBRL Taxonomy Extension Calculation Linkbase***
101.DEF	XBRL Taxonomy Extension Definition Linkbase***
101.LAB	XBRL Taxonomy Extension Label Linkbase***
101.PRE	XBRL Taxonomy Extension Presentation Linkbase***

_______________

*	Filed herewith.
**	Furnished herewith.
***	Users of this interactive data file are advised pursuant to Rule 406T of Regulations S-T that this interactive data file is deemed not filed or part of a registration statement or prospectus for purposes of sections 11 or 12 of the Securities Act of 1933, is deemed not filed for purposes of section 18 of the Securities Exchange Act of 1934, and otherwise is not subject to liability under these sections.

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SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of New York, State of New York, on August 7, 2014.

NEOSTEM, INC.

By: /s/ Robin L. Smith, M.D.

Name: Robin L. Smith, M.D.

 Title: Chief Executive Officer

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

Signature	Title	Date
/s/ Robin L. Smith, M.D. Robin L. Smith, M.D.	Director, Chief Executive Officer and  Chairman of the Board (Principal Executive Officer)	August 7, 2014
/s/ Robert Dickey IV Robert Dickey IV	Chief Financial Officer (Principal Financial Officer)	August 7, 2014
/s/ Joseph Talamo Joseph Talamo	Vice President, Corporate Controller and Chief  Accounting Officer (Principal Accounting Officer)	August 7, 2014

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EX-10.3

Exhibit 10.3

EXECUTION VERSION

EMPLOYMENT AGREEMENT

This Employment Agreement (the “Agreement”) is made as of April 11, 2014 (the “Effective Date”), by and between Hans Keirstead, Ph.D., an individual (“Executive”), and California Stem Cell, Inc., a Delaware corporation (the “Company”).

RECITALS

WHEREAS, concurrent with the execution of this Agreement, the Company, NeoStem, Inc. (“NeoStem”), NBS Acquisition Sub I, Inc., a Delaware corporation and a wholly owned subsidiary of NeoStem (“Subco”), and NBS Acquisition Sub II, LLC, a Delaware limited liability company and wholly owned subsidiary of NeoStem (“Subco II”), intend to enter into an Agreement and Plan of Merger (as amended from time to time, the “Merger Agreement”) pursuant to which (i) Subco will be merged with and into the Company with the Company continuing as the surviving company and as a direct wholly owned subsidiary of NeoStem (the “First Merger”) and (ii) as soon as practicable thereafter, the Company will be merged with and into Subco II (the “Second Merger” and together with the First Merger, the “Mergers”), with Subco II surviving the Second Merger, in each case on the terms and subject to the conditions set forth in the Merger Agreement,

WHEREAS, the Company and Executive are parties to that certain Employment Agreement, dated December 1, 2013 (the “Original Employment Agreement”);

WHEREAS, effective upon the Closing (as defined in the Merger Agreement), the Company desires to continue to employ Executive to provide services to the Company, and provide Executive with certain compensation and benefits in return for these services;

WHEREAS, Executive wishes to continue to be employed by the Company following the Closing and provide services to the Company in return for certain compensation and benefits, including the benefits provided under this Agreement; and

WHEREAS, Executive and the Company intend that, effective upon the Closing, the Original Employment Agreement shall terminate and be null and void and that this Agreement shall become effective and replace the Original Employment Agreement.

AGREEMENT

NOW, THEREFORE, in consideration of the mutual promises and covenants contained herein, it is hereby agreed by and between the parties hereto as follows:

1.Employment.Executive shall serve as the President of the Company (after the Closing (as defined in the Merger Agreement), the Company may add an additional title of Executive Vice President, NeoStem). Executive shall diligently perform all services as may be reasonably assigned to him and shall exercise such power and authority as may from time to time be delegated to him. During his employment, Executive (i) shall devote all his working time and attention to the business and affairs of the Company (excluding any vacation and sick leave to which Executive is entitled), render such services to the best of his ability, and use his reasonable best efforts to promote the interests of the Company, (ii) shall not engage in any other employment, consulting or other business activity that would create a conflict of interest with his services to the Company, (iii) shall

not assist any person or entity in competing with the Company or in preparing to compete with the Company and (iv) shall comply with the Company’s policies and rules, as they may be in effect from time to time. Notwithstanding the foregoing, Executive shall be entitled to (A) deliver lectures or fulfill speaking engagements, or (B) manage personal investments, so long as, in each such case, such activities do not (a) significantly interfere with the performance of Executive’s responsibilities as an employee of the Company in accordance with the terms and conditions of this Agreement, or (b) create a conflict of interest with his services to the Company; provided, however, that Executive shall not serve on the board of directors of any entity or organization (including any civic or charitable boards or committees) without prior written approval from the Company’s or NeoStem’s Board of Directors, NeoStem’s Compensation Committee, or its designee.

2.Term.The term of this Agreement shall commence upon the Effective Date and, unless terminated in accordance with Section4 of this Agreement, shall continue for a period of three (3) years from the Effective Date (the “Term”), provided that, in the event that the Executive’s employment were to continue upon expiration of the Term, such employment will be on an “at will” basis.

3.Compensation. As compensation for Executive’s services to be performed hereunder, the Company shall provide Executive with the following compensation and benefits during the Term:

A.Base Salary.Executive’s base salary shall be $285,000 (if annualized) (the “Base Salary”). Executive’s Base Salary shall be payable in accordance with the Company’s current payroll practices. The Base Salary shall be reviewed, at least annually, and may, by action and in the discretion of the Company’s or NeoStem’s Compensation Committee, or its designee, be increased or decreased, at any time or from time to time.

B.Bonus. Executive shall be eligible to receive such bonus payment or incentive compensation of up to 30% of his Base Salary as may be determined at any time or from time to time by the Company’s Board of Directors, its Compensation Committee, or its designee in its discretion. In connection therewith, Executive shall be entitled to participate in any bonus program that the Company may adopt from time to time applicable to other executive employees of comparable stature.

C.Stock Incentives. Subject to approval of the Board or any authorized committee thereof, Executive will be eligible to receive grants of stock options, restricted stock or other equity awards as may from time to time be granted or awarded pursuant to the terms and conditions of the Company’s equity compensation plans and agreements thereunder.

D.Vacation. Executive shall be entitled to vacation in accordance with the Company’s standard policy.

E.Holiday Pay and Sick Leave. The Company shall provide Executive with holiday pay and paid sick leave as provided by the Company from time to time to its other executive employees of comparable stature.

F.Business Expenses. The Company will reimburse Executive for reasonable and necessary travel and accommodation costs, entertainment and other business expenses incurred as a necessary part of discharging Executive’s duties hereunder and, in connection therewith, will continue to pay annual membership dues for up to two private clubs that may be used for business purposes in California of Executive’s choice and reimburse Executive for up to $10,000 in membership dues related to each club, subject to receipt of reasonable and appropriate documentation as required by the Company, and pursuant to applicable Company policy and procedure.

G.Welfare Benefit Plans. Executive and/or Executive’s dependents, as the case may be shall be eligible for participation in and shall receive all benefits under welfare benefit plans, practices, policies and programs provided by the Company and its subsidiaries from time to time (including, without limitation, medical, prescription, dental, disability, salary continuance, employee life, group life, accidental death and travel accident insurance plans and programs) that the Company may adopt from time to time applicable to other executive employees of comparable stature.

H.Savings and Retirement Plans. Executive shall be entitled to participate in all savings and retirement plans, practices, policies and programs provided by the Company and its subsidiaries from time to time to other executive employees of comparable stature.

I.Withholding and Other Taxes. Any compensation paid to Executive hereunder shall be subject to such withholding and other taxes as are required by applicable law.

4.Termination.

A.Termination for Cause; Resignation

1. The Company may terminate the Executive’s employment hereunder at any time for Cause (as defined below) upon written notice to the Executive. The Executive may voluntarily resign from his employment upon not less than fourteen (14) days prior written notice to the Company; provided, however, the Company reserves the right, upon written notice to the Executive, to accept the Executive’s notice of voluntary resignation and to accelerate such notice and make the Executive’s resignation effective immediately, or on such other date prior to the Executive’s intended last day of work as the Company deems appropriate. It is understood and agreed that the Company’s election to accelerate the Executive’s notice of resignation shall not be deemed a termination by the Company without Cause.

2.As used in this Agreement, “Cause” means, as determined in the Company’s sole discretion and judgment, the Executive’s: (a) willful misconduct or gross negligence in the performance of his duties; (b) commission of, indictment for, conviction of, or pleading of guilty or nolo contendere to, a felony or any crime involving moral turpitude; (c) engagement of any act of theft, embezzlement, fraud, malfeasance, dishonesty or misappropriation against the Company, any of its affiliates or any of their respective customers or suppliers; (d) breach of or announced intention to breach any fiduciary duty owed to the Company or any of its affiliates (including, without limitation, the duty of care and the duty of loyalty); (e) material failure or announced intention to fail to perform his or her duties under or to breach this Agreement (other than any such failure resulting from incapacity due to physical or mental illness); (f) failure or announced intention to fail to comply with any valid and legal directive of the Company; or (g) failure or announced intention to fail to comply

with the Company’s material written policies or rules, as they may be in effect from time to time during the Term.

3.If the employment relationship hereunder is terminated by the Company for Cause or by the voluntary resignation of the Executive, the Executive shall, in full discharge of all of the Company’s obligations to the Executive, be entitled to receive, and the Company’s sole obligation under this Agreement or otherwise with respect to the Executive’s employment shall be to pay or provide to the Executive, the following (collectively, the “Accrued Obligations”): (a) the Executive’s earned, but unpaid, Base Salary through the termination date; (b) approved reimbursable expenses; and (c) any amounts or benefits that are vested amounts or vested benefits or that the Executive is otherwise entitled to receive under any plan, program, policy or practice (with the exception of those, if any, relating to severance) on the termination date, in accordance with such plan, program, policy, or practice.

B.Termination Without Cause. The Company may terminate the Executive’s employment hereunder at any time without Cause upon written notice to the Executive. If the employment relationship hereunder is terminated by the Company without Cause, the Executive shall be entitled to receive, and the Company’s sole obligation under this Agreement or otherwise with respect to the Executive’s employment shall be to pay or provide to the Executive, the following, in full discharge of all of the Company’s obligations to the Executive: (A) the Accrued Obligations; and (B) the continuation of the Executive’s Base Salary at the rate in effect as of the termination date for three months, in regular and equal installments in accordance with the Company’s customary payroll practices and procedures, commencing on the first regular pay date following the eighth day after the Executive signs, returns, and does not revoke a general release agreement in favor of and satisfactory to the Company and its related parties.

5.Resignation from all Positions. Upon the termination of Executive’s employment by the Company, Executive shall be deemed to have resigned, as of the date of such termination, from all positions he then holds as an officer or employee, and as a director of the Company or any of its subsidiaries.

6.No Conflicting Obligations. Executive represents and warrants to the Company that he has the unfettered right to enter into this Agreement and to perform all of the terms, covenants and conditions herein, and Executive has not done or permitted to be done anything which may curtail or impair any of the rights granted to the Company herein.

7.Successors; Assignment.

A.Company’s Successors. This Agreement shall be binding upon any successor (whether direct or indirect and whether by purchase, lease, merger, consolidation, liquidation or otherwise) to all or substantially all of the Company’s business and/or assets. For all purposes under this Agreement, the term “Company” shall include any successor to the Company’s business and/or assets.

B.Executive’s Successors. This Agreement and all rights of Executive hereunder shall inure to the benefit of, and be enforceable by, Executive’s personal or legal representatives, executors, administrators, successors, heirs, distributes, devisees and legatees.

C.Assignment. This Agreement and all rights and obligations of Executive hereunder are personal to Executive and may not be transferred or assigned by Executive at any time. The Company may assign its rights under this Agreement to NeoStem or to any entity that assumes the Company’s obligations hereunder in connection with the Mergers.

8.Prior Contracts. To the extent that the terms of any prior employment contract or agreement between the Company and Executive contradict this Agreement, the terms of such prior employment contract or agreement are hereby cancelled and shall be of no further force and effect.

9.Severability. If any provision of this Agreement shall be found invalid by any court of competent jurisdiction, such findings shall not affect the validity of any other provision hereof and the invalid provisions shall be deemed to have been severed herefrom.

10.Waiver of Breach. The waiver by any party of the breach of any provision of this Agreement by the other party or the failure of any party to exercise any right granted to it hereunder shall not operate or be construed as the waiver of any subsequent breach by such other party nor the waiver of the right to exercise any such right.

11.Notices. Notices and all other communications contemplated by this Agreement shall be in writing and shall be deemed to have been duly given when personally delivered, when delivered by FedEx with delivery charges prepaid, or when mailed by U.S. registered or certified mail, return receipt requested and postage prepaid. In the case of Executive, mailed notices shall be addressed to him at the home address that he most recently communicated to the Company in writing. In the case of the Company, mailed notices shall be addressed to its corporate headquarters, and all notices shall be directed to the attention of its Secretary.

12.Complete Agreement. This Agreement, any Indemnification Agreement executed between the Company and Executive, and any Confidentiality Agreement executed between the Company and Executive (including but not limited to the Executive’s Employee Confidentiality and Invention Assignment Agreement) contain a complete statement of all the arrangements between the parties with respect to Executive’s employment by the Company and supersede any and all prior or existing agreements between them concerning Executive’s employment and any emoluments arising thereunder. For the sake of clarity, the Preamble and Recitals set forth above are deemed to form a part of the Agreement.

13.Modification. This Agreement may be amended, modified, superseded or cancelled only by a written instrument signed by each of the parties hereto.

14.Governing Law; Dispute Resolution. This Agreement and any controversy arising out of or relating to this Agreement shall be governed by and construed in accordance with the applicable laws of the State of New York, without regard to conflict of law principles that would result in the application of any law.

15.Attorneys’ Fees. In the event any party hereto commences legal action in connection with this Agreement, the prevailing party shall be entitled to its/his reasonable attorneys’ fees, costs and expenses incurred in such action and in any appeal therefrom.

16.Headings. The headings in this Agreement are solely for the convenience of reference and shall not affect its interpretation.

17.Counterparts.This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. Counterparts may be delivered via facsimile, electronic mail (including pdf) or other transmission method

and any counterpart so delivered shall be deemed to have been duly and validly delivered and be valid and effective for all purposes.

18.Effectiveness. This Agreement shall become effective only upon the consummation of the First Merger and the Original Employment Agreement shall terminate and become null and void automatically upon the consummation of the First Merger.

[Signature Page Follows][Signature page to Employment Agreement]

IN WITNESS WHEREFORE, the parties hereto have executed this Employment Agreement as of the day and year first set forth above.

COMPANY:

CALIFORNIA STEM CELL, INC.

By: /s/ Jason Livingston

EXECUTIVE:

/s/ Hans Keirstead

EX-10.4

Exhibit 10.4

May 2, 2014

Dr. Robert Dillman

1200 Polaris Drive

Newport Beach, CA 92660

Dear Dr. Dillman:

We are pleased to provide you with this letter confirming your offer (the “Offer”) of employment with NeoStem Oncology, LLC (“NeoStem Oncology” or the “Company”) a wholly owned subsidiary of NeoStem, Inc., (the “Parent” or “NeoStem”).¹ This letter is to confirm the terms of your employment upon acceptance.

1) The commencement date of your employment with NeoStem Oncology shall be on the day following the Closing (the “Commencement Date”). This Offer is subject in all respects to the Closing having occurred.

2) You will continue to work at your current location. Your title will be Vice President, Oncology. You shall devote your best efforts and full time and attention to the performance of the services customarily required of such position and to such other duties as may be reasonably requested by management. Following the Commencement Date, your title and reporting structure may be reviewed.

3) In consideration for your services, you shall receive a base salary at an annual rate of $325,000 (“Base Salary”) which shall be paid in accordance with the Parent’s standard payroll practices. You will be eligible for a bonus based on Company and personal performance in accordance with your current bonus opportunity subject to approval of the Compensation Committee of the Board of Directors (the “Compensation Committee”) of the Parent. Your next base salary review will be conducted in accordance with the Parent’s annual review cycle, with any compensation changes effective during the first quarter of 2015.

4) Your credited service date will be transferred to the Company and your years of service with CSC will be recognized for the purpose of determining benefits under any of the Company’s service based compensation or benefit programs as allowed by law.

5) Subject to approval of the Compensation Committee, you will receive options (the “Options”) to 45,000 shares of the Parent’s Common Stock under and subject to the terms and conditions of the Parent’s Amended and Restated 2009 Equity Compensation Plan. The Options shall have a per share exercise price equal to the closing price of the Common Stock on the date of grant and shall vest and become exercisable subject to your continued employment, as to 15,000 Options on the one year anniversary of your Commencement Date and as to 15,000 Options on the second year anniversary of your Commencement Date and as to 15,000 Options on the third year anniversary of your Commencement Date.

1.    Pursuant to the terms of a merger agreement dated as of April 11, 2014, Subco I (a newly-formed wholly-owned subsidiary of NeoStem) will be merged (the “Merger”) with and into California Stem Cell, Inc. (‘CSC”) in the first merger, with CSC surviving as a wholly-owned subsidiary of NeoStem. Immediately following, CSC will be merged with and into NeoStem Oncology, LLC. NeoStem Oncology, LLC will be the surviving entity. The closing of the Merger (The “Closing”) is expected to be in May 2014.

6) In addition to the compensation stated above, you will be entitled to participate in benefits generally available to other employees of the Parent, in accordance with the Parent and its Professional Employer Organization’s (PEO) policies and procedures.

7) This position is an exempt position for purposes of federal and state wage-hour laws, which means that you will not be receiving any overtime payment for hours worked in excess of 40 hours in a given workweek.

In accepting our offer of employment, you certify your understanding that your employment will be on an at-will basis, and that neither you nor the Company or Parent has entered into a contract regarding the terms or the duration of your employment except as may be set forth herein. However, you hereby agree that should you desire to terminate your employment with the Company you will provide it with no less than thirty (30) days’ prior written notice. You also agree that prior to the Commencement Date you will execute and be bound by the Parent’s various policies, including but not limited to its Employee Confidentiality and Invention Assignment Agreement, Statement of Policy on Insider Trading and Policy Regarding Special Trading Procedures.

This Offer is further to subject to your successful completion of a mandatory substance abuse test and background check.

Please indicate your acceptance of this offer by signing and returning this letter to:

David Schloss

NeoStem, Inc.

420 Lexington Avenue, Suite 350

New York, NY 10170

We look forward to your joining the NeoStem family and are confident that you will enjoy a smooth transition and play a key role in our development. If you have any questions, please don’t hesitate to reach out to me directly at 646-606-2192.

Best regards,

/s/ David Schloss

David Schloss

Vice President, Human Resources

NeoStem, Inc.

Accepted and Agreed:

/s/ Robert Dillman

Dr. Robert Dillman

Date: May 5, 2014

EX-10.5

Exhibit 10.5

August 4, 2014

Ms. Catherine M. Vaczy

140 East 28^th Street

#11C

New York, NY 10021

Dear Catherine:

This letter serves as an amendment to your employment agreement dated as of January 26, 2007 (the “2007 Agreement”), as thereafter amended by amendments on January 9, 2008, August 29, 2008, reinstated and extended on July 8, 2009, amended and extended on July 7, 2010, amended and extended on January 6, 2012, amended and extended on November 13, 2012, amended and extended on July 12, 2013 and further amended on March 11, 2014 (the 2007 Agreement as so amended and extended, the “Original Agreement”) with respect to your service to the Company as its General Counsel. Except as set forth herein the Original Agreement shall remain unchanged. This letter agreement shall modify the Original Agreement with respect to those different and additional terms as follows. The stock options granted to you by the Company to date or to be granted to you by the Company in the future shall remain exercisable despite any termination of your employment for a period of not less than four years from the date of your termination of employment.

Terms not otherwise defined herein shall have the meaning ascribed to them in the Original Agreement. Except as set forth herein the terms of the Original Agreement shall remain unchanged.                                     

NeoStem, Inc.

By: /s/ Robin L. Smith

Name:Robin L. Smith

Title:CEO

ACKNOWLEDGED AND AGREED:

/s/ Catherine M. Vaczy

Catherine M. Vaczy

EX-31.1

Exhibit 31.1

CERTIFICATION

I, Robin Smith, M.D., certify that:

1.  I have reviewed this Quarterly Report on Form 10-Q of NeoStem, Inc.;

2.  Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3.  Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4.  The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

a)  Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by  this report based on such evaluation; and

d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5.  The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

a)  All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date: August 7, 2014

/s/ Robin Smith, M.D.

Name: Robin Smith, M.D.

Title: Chief Executive Officer of NeoStem, Inc.

A signed original of this written statement required by Section 302 has been provided to NeoStem, Inc. and will be retained by NeoStem, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

EX-31.2

Exhibit 31.2

CERTIFICATION

I, Robert Dickey IV, certify that:

1.  I have reviewed this Quarterly Report on Form 10-Q of NeoStem, Inc.;

2.  Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3.  Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4.  The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

a)  Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by  this report based on such evaluation; and

d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5.  The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

a)  All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date: August 7, 2014

/s/ Robert Dickey IV

Name: Robert Dickey IV

Title: Chief Financial Officer of NeoStem, Inc.

A signed original of this written statement required by Section 302 has been provided to NeoStem, Inc. and will be retained by NeoStem, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

EX-32.1

Exhibit 32.1

CERTIFICATION PURSUANT TO

18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of NeoStem, Inc. (the “Company”) on Form 10-Q for the quarter ended June 30, 2014 filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Robin Smith, M.D., Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, to my knowledge that:

1. The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 as amended; and

2. The information contained in the Report fairly presents, in all material respects, the financial condition of the Company as of the dates presented and the results of operations of the Company for the periods presented.

Dated:  August 7, 2014

/s/ Robin Smith, M.D.

Robin Smith, M.D.

Chief Executive Officer

The foregoing certification is being furnished solely pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of Section 1350, Chapter 63 of Title 18, United States Code) and is not being filed as part of the Form 10-Q or as a separate disclosure document.

A signed original of this written statement required by Section 906 has been provided to NeoStem, Inc. and will be retained by NeoStem, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

EX-32.2

Exhibit 32.2

CERTIFICATION PURSUANT TO

18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of NeoStem, Inc. (the “Company”) on Form 10-Q for the quarter ended June 30, 2014 filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Robert Dickey IV, Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, to my knowledge that:

1. The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 as amended; and

2. The information contained in the Report fairly presents, in all material respects, the financial condition of the Company as of the dates presented and the results of operations of the Company for the periods presented.

Dated:  August 7, 2014

/s/ Robert Dickey IV

Robert Dickey IV

Chief Financial Officer

The foregoing certification is being furnished solely pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of Section 1350, Chapter 63 of Title 18, United States Code) and is not being filed as part of the Form 10-Q or as a separate disclosure document.

A signed original of this written statement required by Section 906 has been provided to NeoStem, Inc. and will be retained by NeoStem, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

XML

Available-for-Sale-Securities Classification of the available-for-sale securities (Details) (USD $)	Jun. 30, 2014
Available-for-sale Securities [Abstract]
Cash	$ 27,456,500
Marketable securities	920,800
Total	$ 28,377,300

XML

Shareholders' Equity Restricted Stock (Details) (USD $)	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Stock Issued During Period, Shares, Restricted Stock Award, Gross	456,709	304,402
Stock Issued During Period, Value, Restricted Stock Award, Gross	$ 3,389,700	$ 1,858,300
weighted average estimated fair value of restricted stock	$ 7.42	$ 6.10

XML

Accrued Liabilities Accrued Liabilities (Details) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Accrued Liabilities [Abstract]
Salaries, employee benefits and related taxes	$ 1,443.2	$ 2,325.8
Professional fees	651.7	544.8
License fees	100.0	500.0
Other	392.4	647.4
Accrued Liabilities	$ 2,587.3	$ 4,018.0

XML

Share-Based Compensation Share-Based Compensation (Details) (USD $)	3 Months Ended		6 Months Ended								6 Months Ended	3 Months Ended		6 Months Ended		3 Months Ended		6 Months Ended		3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014 Stock Option [Member]	Jun. 30, 2014 Warrants	Jun. 30, 2013 Warrants	Dec. 31, 2013 Warrants	Jun. 30, 2014 Stock Options [Member]	Dec. 31, 2013 Stock Options [Member]	Jun. 30, 2014 Restricted Stock [Member]	Jun. 30, 2014 Cost of revenue	Jun. 30, 2013 Cost of revenue	Jun. 30, 2014 Cost of revenue	Jun. 30, 2013 Cost of revenue	Jun. 30, 2014 Research and development	Jun. 30, 2013 Research and development	Jun. 30, 2014 Research and development	Jun. 30, 2013 Research and development	Jun. 30, 2014 Selling, General and Administrative Expenses [Member]	Jun. 30, 2013 Selling, General and Administrative Expenses [Member]	Jun. 30, 2014 Selling, General and Administrative Expenses [Member]	Jun. 30, 2013 Selling, General and Administrative Expenses [Member]	Jun. 30, 2014 Stock Option [Member]	Jun. 30, 2013 Stock Option [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Allocated Share-based Compensation Expense	$ 1,759,700	$ 1,095,700	$ 5,653,500	$ 3,314,200								$ 98,500	$ 58,500	$ 236,600	$ 145,000	$ 371,600	$ 129,800	$ 848,400	$ 347,100	$ 1,289,600	$ 907,400	$ 4,568,500	$ 2,822,100
Unrecognized compensation cost					6,814,900	33,400					262,900
Expected weighted-average period in years of compensation cost to be recognized					5 years 7 days	1 year 18 days					2 months 9 days
Total fair value of shares vested						$ 15,000	$ 80,900																	$ 2,552,200	$ 1,646,300
Weighted average estimated fair value of shares granted						$ 0.00		$ 3.51	$ 4.92	$ 4.58

XML

Goodwill and Other Intangible Assets Intangible Amortization Expense (Details) (USD $)	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013
Finite-Lived Intangible Assets [Line Items]
Amortization of Intangible Assets	$ 302,600	$ 302,600
Cost of revenue
Finite-Lived Intangible Assets [Line Items]
Amortization of Intangible Assets	158,400	195,000
Research and development
Finite-Lived Intangible Assets [Line Items]
Amortization of Intangible Assets	54,200	17,600
Selling, general and administrative
Finite-Lived Intangible Assets [Line Items]
Amortization of Intangible Assets	$ 90,000	$ 90,000

XML

Commitments and Contingencies (Tables)

6 Months Ended

Jun. 30, 2014

Commitments and Contingencies [Abstract]

Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]

A summary of future minimum rental payments required under operating leases that have initial or remaining terms in excess of one year as of June 30, 2014 are as follows (in thousands):  

Years ended	Operating Leases
2014	$	675.3
2015	1,160.5
2016	997.9
2017	697.8
2018	5.9
Total minimum lease payments	$	3,537.4

XML

Commitments and Contingencies (Details) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Operating Leases, Future Minimum Payments Due [Abstract]
2013	$ 675,300		$ 675,300
2014	1,160,500		1,160,500
2015	997,900		997,900
2016	697,800		697,800
Thereafter	5,900		5,900
Total minimum lease payments	3,537,400		3,537,400
Operating Leases, Rent Expense	$ 300,000	$ 300,000	$ 500,000	$ 600,000

XML

Acquisition (Tables)

6 Months Ended

Jun. 30, 2014

Business Combinations [Abstract]

Business Acquisition, Pro Forma Information [Table Text Block]

The following supplemental table presents unaudited consolidated pro forma financial information as if the closing of the acquisition of CSC had occurred on January 1, 2013 (in thousands, except per share amounts):

	Three Months Ended June 30, 2014						Six Months Ended June 30, 2014
	(As Reported)			(Proforma)			(As Reported)			(Proforma)
Revenues	$	4,489		$	4,982		$	8,545		$	9,255
Net loss	$	(12,770	)	$	(13,574	)	$	(26,600	)	$	(29,097	)
Net loss attributable to NBS	$	(12,605	)	$	(13,409	)	$	(26,287	)	$	(28,784	)
Net loss per share attributable to NBS	$	(0.40	)	$	(0.36	)	$	(0.88	)	$	(0.82	)

	Three Months Ended June 30, 2013						Six Months Ended June 30, 2013
	(As Reported)			(Proforma)			(As Reported)			(Proforma)
Revenues	$	4,359		$	4,596		$	6,883		$	7,282
Net loss	$	(8,626	)	$	(9,830	)	$	(17,490	)	$	(19,963	)
Net loss attributable to NBS	$	(8,575	)	$	(9,780	)	$	(17,376	)	$	(19,849	)
Net loss per share attributable to NBS	$	(0.46	)	$	(0.41	)	$	(0.99	)	$	(0.87	)

Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]

The preliminary fair value of assets acquired and liabilities assumed on May 8, 2014 is as follows (in thousands):

Cash and cash equivalents	$	51.2
Accounts receivable trade, net	45.1
Prepaids and other current assets	19.2
Property, plant and equipment, net	1,040.9
Other assets	201.0
Goodwill	14,961.9
In-Process R&D	35,790.0
Accounts payable	(333.1		)
Accrued liabilities	(2,014.1		)
Deferred tax liability	(14,509.3		)
	$	35,252.8

XML

Shareholders' Equity Reverse Stock Split (Details) (USD $)	Jun. 30, 2014	Dec. 31, 2013	Jul. 26, 2013
Statement of Stockholders' Equity [Abstract]
Common Stock, Par Value	$ 0.001	$ 0.001	$ 0.001

XML

Loss Per Share (Details)	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013
Warrants
Class of Stock [Line Items]
Dilutive Securities Excluded From Computation Of Earnings Per Share, Shares	3,623,956	5,430,137
Stock Options [Member]
Class of Stock [Line Items]
Dilutive Securities Excluded From Computation Of Earnings Per Share, Shares	4,204,270	2,647,437
Restricted Stock [Member]
Class of Stock [Line Items]
Dilutive Securities Excluded From Computation Of Earnings Per Share, Shares	205,231	73,500

XML

Acquisition (Details) (USD $)	2 Months Ended	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013	May 08, 2014	Dec. 31, 2013
Business Acquisition [Line Items]
Revenues		$ 4,488,932	$ 4,359,406	$ 8,544,507	$ 6,883,318
Net loss		(12,769,492)	(8,625,641)	(26,599,576)	(17,489,971)
Business Combination, Pro Forma Information, Revenue of Acquiree since Acquisition Date, Actual	10,000
Common Stock, Shares, Issued	34,939,223	34,939,223		34,939,223		5,329,593	27,196,537
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High						90,000,000
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net	20,300,000	20,300,000		20,300,000
Acquisition-related contingent consideration	20,640,000	20,640,000		20,640,000		10,800,000	9,450,000
Business Acquisition, Transaction Costs						35,300,000
Cash and cash equivalents						51,200
Accounts receivable, net of allowance for doubtful accounts of $390,118 and $391,829 at March 31, 2014 and December 31, 2013, respectively						45,100
Prepaid expenses and other current assets						19,200
Property, plant and equipment, net						1,040,900
Other assets						201,000
Goodwill	26,079,536	26,079,536		26,079,536		14,961,900	11,117,770
Equity Issued in Business Combination, Fair Value Disclosure						24,500,000
Intangible assets, net						35,790,000
Accounts Payable, Current						(333,100)
Accrued Liabilities, Current						(2,014,100)
Deferred Tax Liabilities, Net, Noncurrent						(14,509,300)
Business Acquisition, Pro Forma Net Income (Loss)	(2,300,000)
Basic and diluted loss per share attributable to NeoStem, Inc. common stockholders	$ (0.07)	$ (0.40)	$ (0.46)	$ (0.88)	$ (0.99)
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net						35,252,800
NeoStem Oncology [Member]
Business Acquisition [Line Items]
Business Acquisition, Pro Forma Revenue		4,982,000	4,596,000	9,255,000	7,282,000
Business Acquisition, Pro Forma Net Income (Loss)		(13,574,000)	(9,830,000)	(29,097,000)	(19,963,000)
Business Combination, Pro Forma Information, Earnings or Loss of Acquiree since Acquisition Date, Actual		(13,409,000)	(9,780,000)	(28,784,000)	(19,849,000)
Business Acquisition, Pro Forma Earnings Per Share, Diluted		$ (0.36)	$ (0.41)	$ (0.82)	$ (0.87)
NeoStem, Inc. [Member]
Business Acquisition [Line Items]
Revenues		4,489,000	4,359,000	8,545,000	6,883,000
Net loss		(12,770,000)	(8,626,000)	(26,600,000)	(17,490,000)
Net Income (Loss) Attributable to Parent		(12,605,000)	(8,575,000)	(26,287,000)	(17,376,000)
Goodwill	$ 26,079.5	$ 26,079.5		$ 26,079.5			$ 11,117.7
Basic and diluted loss per share attributable to NeoStem, Inc. common stockholders		$ (0.40)	$ (0.46)	$ (0.88)	$ (0.99)

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Shareholders' Equity Warrant Exercises (Details) (USD $) In Millions, except Share data, unless otherwise specified	0 Months Ended		6 Months Ended
	Sep. 30, 2012	Sep. 30, 2012 Private Placement [Member]	Jun. 30, 2014 Warrant holder A [Member]
Stock Options and Warrants [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights			265,250
Investment Warrants, Exercise Price	$ 14.50	$ 5.10
Proceeds from Issuance of Warrants			$ 1.4

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Goodwill and Other Intangible Assets Goodwill (Details) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Goodwill [Abstract]
Future Amortization Expense, Year One	$ 302,600
Future Amortization Expense, Year Two	605,200
Future Amortization Expense, Year Three	605,200
Future Amortization Expense, Year Four	605,200
Future, Amortization Expense, Year Five	605,200
Thereafter	46,639,600
Finite-Lived Intangible Assets, Future Amortization Expense	$ 49,363,000	$ 13,875,600

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Summary of Significant Accounting Policies

6 Months Ended

Jun. 30, 2014

Summary of Significant Accounting Policies [Abstract]

Summary of Significant Accounting Policies [Text Block]

Summary of Significant Accounting Policies

In addition to the policies below, our significant accounting policies are described in Note 2 of the Notes to Consolidated Financial Statements included in our Annual Report on Form 10-K for the year ended December 31, 2013. There were no changes during the six months endedJune 30, 2014.

Cash and Cash Equivalents

Cash and cash equivalents include short-term, highly liquid, investments with maturities of ninety days or less when purchased.

Marketable Securities

The Company determines the appropriate classification of our marketable securities at the time of purchase and reevaluate such designation at each balance sheet date. All of our marketable securities are considered as available-for-sale and carried at estimated fair values and reported in either cash equivalents or marketable securities. Unrealized gains and losses on available-for-sale securities are excluded from net income and reported in accumulated other comprehensive income (loss) as a separate component of stockholders' equity. Other income (expense), net, includes interest, dividends, amortization of purchase premiums and discounts, realized gains and losses on sales of securities and other-than-temporary declines in the fair value of securities, if any. The cost of securities sold is based on the specific identification method. We regularly review all of our investments for other-than-temporary declines in fair value. Our review includes the consideration of the cause of the impairment, including the creditworthiness of the security issuers, the number of securities in an unrealized loss position, the severity and duration of the unrealized losses, whether we have the intent to sell the securities and whether it is more likely than not that we will be required to sell the securities before the recovery of their amortized cost basis. When we determine that the decline in fair value of an investment is below our accounting basis and this decline is other-than-temporary, we reduce the carrying value of the security we hold and record a loss for the amount of such decline.

Accounts Receivable

Accounts receivable are carried at original invoice amount less an estimate made for doubtful accounts. The Company applies judgment in connection with establishing the allowance for doubtful accounts. Specifically, the Company analyzes the aging of accounts receivable balances, historical bad debts, customer concentration and credit-worthiness, current economic trends and changes in the Company’s customer payment terms. Significant changes in customer concentrations or payment terms, deterioration of customer credit-worthiness or weakening economic trends could have a significant impact on the collectability of the receivables and the Company’s operating results. If the financial condition of the Company’s customers were to deteriorate, resulting in an impairment of their ability to make payments, additional allowances may be required. Management regularly reviews the aging of receivables and changes in payment trends by its customers, and records a reserve when it believes collection of amounts due are at risk.

Inventories

The Company, through its PCT subsidiary, regularly enters into contracts with clients for services that have multiple stages and are dependent on one another to complete the contract and recognize revenue. The Company's inventory primarily represents work in process for costs incurred on such projects at PCT that have not been completed. The Company reviews these projects periodically to determine that the value of each project is stated at the lower of cost or market.

Goodwill and Other Intangible Assets

Goodwill is the excess of purchase price over the fair value of identified net assets of businesses acquired. The Company’s intangible assets with an indefinite life are related to in process research and development ("IPR&D") programs acquired in the Amorcyte and CSC acquisitions, as the Company expects future research and development on these programs to provide the Company with substantial benefit for a period that extends beyond the foreseeable horizon. Intangible assets with indefinite useful lives are measured at their respective fair values as of the acquisition date. The Company does not amortize goodwill and intangible assets with indefinite useful lives. Intangible assets related to IPR&D projects are considered to be indefinite-lived until the completion or abandonment of the associated R&D efforts. If and when development is complete, which generally occurs if and when regulatory approval to market a product is obtained, the associated assets would be deemed finite-lived and would then be amortized based on their respective estimated useful lives at that point in time.

The Company reviews goodwill and indefinite-lived intangible assets at least annually for possible impairment. Goodwill and indefinite-lived intangible assets are reviewed for possible impairment between annual tests if an event occurs or circumstances change that would more likely than not reduce the fair value of the reporting unit below its carrying value. The Company tests its goodwill and indefinite-lived intangible assets each year on December 31. The Company reviews the carrying value of goodwill and indefinite-lived intangible assets utilizing a discounted cash flow model, and, where appropriate, a market value approach is also utilized to supplement the discounted cash flow model. The Company makes assumptions regarding estimated future cash flows, discount rates, long-term growth rates and market values to determine each reporting unit’s estimated fair value.

Amortized intangible assets consist of customer lists, manufacturing technology, tradenames, patents and rights. These intangible assets are amortized on a straight line basis over their respective useful lives.

Revenue Recognition

Clinical Services: The Company recognizes revenue for its (i) process development and (ii) clinical manufacturing services based on the terms of individual contracts.

Revenues associated with process development services generally contain multiple stages that do not have stand-alone values and are dependent upon one another, and are recognized as revenue on a completed contract basis. We recognize revenues when all of the following conditions are met:

• persuasive evidence of an arrangement exists;

• delivery has occurred or the services have been rendered;

• the fee is fixed or determinable; and

• collectability is probable.

The Company considers signed contracts as evidence of an arrangement. The Company assesses whether the fee is fixed or determinable based on the payment terms associated with the transaction and whether the payment terms are subject to refund or adjustment. The Company assesses cash collectability based on a number of factors, including past collection history with the client and the client's creditworthiness. If the Company determines that collectability is not reasonably assured, it defers revenue recognition until collectability becomes reasonably assured, which is generally upon receipt of the cash. The Company's arrangements are generally non-cancellable, though clients typically have the right to terminate their agreement for cause if the Company materially fails to perform.

Clinical manufacturing services are generally distinct arrangements whereby the Company is paid for time and materials or for fixed monthly amounts. Revenue is recognized when efforts are expended or contractual terms have been met.

Some client agreements include multiple elements, comprised of process development and clinical manufacturing services. The Company believes that process development and clinical manufacturing services each have stand-alone value because these services can be provided separately by other companies. In accordance with ASC Update No. 2009-13, “Revenue Recognition (Topic 605): Multiple-Deliverable Revenue Arrangements,” the Company (1) separates deliverables into separate units of accounting when deliverables are sold in a bundled arrangement and (2) allocates the arrangement's consideration to each unit in the arrangement based on its relative selling price. 

Clinical Services Reimbursements: The Company separately charges the customers for the expenses associated with certain consumable resources (reimbursable expenses) that are specified in each clinical services contract. On a monthly basis, the Company bills customers for reimbursable expenses and immediately recognizes these billings as revenue, as the revenue is deemed earned as reimbursable expenses are incurred. For the three months endedJune 30, 2014 and 2013, clinical services reimbursements were $1.1 million and $0.4 million, respectively. For the six months endedJune 30, 2014 and 2013, clinical services reimbursements were $1.8 million and $0.8 million, respectively.

Processing and Storage Services: The Company recognizes revenue related to the collection and cryopreservation of cord blood and autologous adult stem cells when the cryopreservation process is completed which is approximately twenty-four hours after cells have been collected. Revenue related to advance payments of storage fees is recognized ratably over the period covered by the advance payments.

New Accounting Pronouncement

In May 2014, the FASB issued ASU 2014-09, "Revenue from Contracts with Customers (Topic 606)." The new revenue recognition standard provides a five-step analysis to determine when and how revenue is recognized. The standard requires that a company recognizes revenue to depict the transfer of promised goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods or services. This ASU is effective for annual periods beginning after December 15, 2016 and will be applied retrospectively to each period presented or as a cumulative-effect adjustment as of the date of adoption. The Company is currently evaluating the impact of the pending adoption of ASU 2014-09 on its consolidated financial statements.

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Fair Value Measurements Fair value hierarchy the Company’s financial assets and liabilities (Details) (USD $)												6 Months Ended
	Jun. 30, 2014	May 08, 2014	Dec. 31, 2013	Jun. 30, 2014 Fair Value, Inputs, Level 1 [Member]	Dec. 31, 2013 Fair Value, Inputs, Level 1 [Member]	Jun. 30, 2014 Fair Value, Inputs, Level 2 [Member]	Dec. 31, 2013 Fair Value, Inputs, Level 2 [Member]	Jun. 30, 2014 Fair Value, Inputs, Level 3 [Member]	Dec. 31, 2013 Fair Value, Inputs, Level 3 [Member]	Jun. 30, 2014 Assets, Total [Member]	Dec. 31, 2013 Assets, Total [Member]	Jun. 30, 2014 Contingent Consideration Classified as Equity [Member]	Dec. 31, 2013 Contingent Consideration Classified as Equity [Member]	Mar. 31, 2014 Amorcyte, LLC [Member]	Dec. 31, 2013 Amorcyte, LLC [Member]	Jun. 30, 2014 Warrants	Dec. 31, 2013 Warrants	Jun. 30, 2014 Contingent Consideration Classified as Equity [Member]	Dec. 31, 2013 Contingent Consideration Classified as Equity [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Acquisition-related contingent consideration	$ 20,640,000	$ 10,800,000	$ 9,450,000									$ 20,640,000	$ 9,450,000	$ 9,900,000	$ 9,500,000
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High		90,000,000
Business Combination, Contingent Consideration Arrangements, Basis for Amount												10790.0
Available-for-sale Securities	920,800		0	0	0	920,800	0	0	0
Marketable securities	920,827		0	0	0	920,800	0	0	0	920,800	0
Warrant Derivative Liabilities	0		23,200	0	0	0	0	0	23,200							0	23,200
Contingent Consideration Classified as Equity, Fair Value Disclosure				0	0	0	0	20,640,000	9,450,000									20,640,000	9,450,000
Accrued Liabilities and Other Liabilities	$ 20,640,000		$ 9,473,200	$ 0	$ 0	$ 0	$ 0	$ 20,640,000	$ 9,473,200

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Goodwill and Other Intangible Assets (Tables)

6 Months Ended

Jun. 30, 2014

Goodwill and Other Intangible Assets [Abstract]

Schedule of Goodwill [Table Text Block]

The following table summarizes the changes in the carrying amount of goodwill (in thousands):

	Total
Balance as of December 31, 2013	$	11,117.7
Goodwill resulting from the acquisition of CSC	14,961.8
Balance as of June 30, 2014	$	26,079.5

Schedule of Finite-Lived Intangible Assets by Major Class [Table Text Block]

The Company's intangible assets and related accumulated amortization as of June 30, 2014 and December 31, 2013 consisted of the following (in thousands):

		June 30, 2014							December 31, 2013
	Useful Life	Gross		Accumulated Amortization			Net		Gross		Accumulated Amortization			Net
Customer list	10 years	$	1,000.0	$	(345.1	)	$	654.9	$	1,000.0	$	(295.1	)	$	704.9
Manufacturing technology	10 years	3,900.0		(1,345.9		)	2,554.1		3,900.0		(1,150.9		)	2,749.1
Tradename	10 years	800.0		(276.1		)	523.9		800.0		(236.1		)	563.9
In process R&D	Indefinite	45,190.0		—			45,190.0		9,400.0		—			9,400.0
Patent rights	19 years	669.0		(228.9		)	440.1		669.0		(211.3		)	457.7
Total Intangible Assets		$	51,559.0	$	(2,196.0	)	$	49,363.0	$	15,769.0	$	(1,893.4	)	$	13,875.6

Schedule of Amortization Expense [Table Text Block]

Total intangible amortization expense was classified in the operating expense categories for the periods included below as follows (in thousands):

	Six Months Ended June 30,
	2014		2013
Cost of revenue	$	158.4	$	195.0
Research and development	54.2		17.6
Selling, general and administrative	90.0		90.0
Total	$	302.6	$	302.6

Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Estimated intangible amortization expense on an annual basis for the succeeding five years is as follow (in thousands):

2014	$	302.6
2015	605.2
2016	605.2
2017	605.2
2018	605.2
Thereafter	46,639.6
	$	49,363.0

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Fair Value Measurements (Tables)

6 Months Ended

Jun. 30, 2014

Fair Value Measurements [Abstract]

Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis, Valuation Techniques [Table Text Block]

• In October 2011, in connection with the Company's acquisition of Amorcyte, contingent consideration obligations were recognized relating to earn out payments equal to 10% of the net sales of the lead product candidate NBS10 (in the event of and following the date of first commercial sale of NBS10), provided that in the event NeoStem sublicenses NBS10, the applicable earn out payment will be equal to 30% of any sublicensing fees, and provided further that NeoStem will be entitled to recover direct out-of-pocket clinical development costs not previously paid or reimbursed and any costs, expenses, liabilities and settlement amounts arising out of claims of patent infringement or otherwise challenging Amorcyte’s right to use intellectual property, by reducing any earn out payments due by 50% until such costs have been recouped in full (the “Earn Out Payments”). The contingent consideration fair value increased from $9.5 million as of December 31, 2013 to $9.9 million as of June 30, 2014. The change in estimated fair value is based or the impact of the time progression through the Phase 2 clinical trial from December 31, 2013 to June 30, 2014, and has been recorded in other expenses in our consolidated statement of operations.

• In May 2014, in connection with the Company's acquisition of CSC, contingent consideration obligations were recognized relating to milestone payments of up to $90.0 million, based on the achievement of certain milestones associated with the future development of the acquired programs. The contingent consideration fair value recognized in the acquisition in May 2014 was $10.8 million. There was no change in estimated fair value as of June 30, 2014.

The fair value of contingent consideration obligations is based on discounted cash flow models using a probability-weighted income approach. The measurements are based upon unobservable inputs supported by little or no market activity based on our own assumptions and experience. The Company bases the timing to complete the development and approval programs on the current development stage of the product and the inherent difficulties and uncertainties in developing a product candidate, such as obtaining U.S. Food and Drug Administration (FDA) and other regulatory approvals. In determining the probability of regulatory approval and commercial success, we utilize data regarding similar milestone events from several sources, including industry studies and our own experience. These fair value measurements represent Level 3 measurements as they are based on significant inputs not observable in the market. Significant judgment is employed in determining the appropriateness of these assumptions as of the acquisition date and for each subsequent period. Accordingly, changes in assumptions could have a material impact on the amount of contingent consideration expense we record in any given period.

The following table sets forth by level within the fair value hierarchy the Company’s financial assets and liabilities that were accounted for at fair value on a recurring basis as of June 30, 2014, and December 31, 2013 (in thousands):

	June 30, 2014								December 31, 2013
	Level 1		Level 2		Level 3		Total		Level 1		Level 2		Level 3		Total
Assets:
Marketable securities - available for sale	$	—	$	920.8	$	—	$	920.8	$	—	$	—	$	—	$	—
	$	—	$	920.8	$	—	$	920.8	$	—	$	—	$	—	$	—
Liabilities:
Warrant derivative liabilities	$	—	$	—	$	—	$	—	$	—	$	—	$	23.2	$	23.2
Contingent consideration	—		—		20,640.0		20,640.0		—		—		9,450.0		9,450.0
	$	—	$	—	$	20,640.0	$	20,640.0	$	—	$	—	$	9,473.2	$	9,473.2

Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]

For those financial instruments with significant Level 3 inputs, the following table summarizes the activity for the six months endedJune 30, 2014 by type of instrument (in thousands):

	Six Months Ended
	June 30, 2014
	Warrants			Contingent Consideration		Total
Beginning liability balance	$	23.2		$	9,450.0	$	9,473.2
Amount issued in acquisition	—			10,790.0		10,790.0
Change in fair value recorded in earnings	—			400.0		400.0
Expiration	(23.2		)	—		(23.2		)
Ending liability balance	$	—		$	20,640.0	$	20,640.0

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Income Taxes Net Operating Loss Carry Forward (Details) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Operating Loss Carryforwards [Line Items]
Operating Loss Carryforwards		$ 110,600,000
Deferred Tax Liabilities, Net, Noncurrent	$ 18,983,288	$ 4,379,226

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Fair Value Measurements Financial instruments with significant Level 3 inputs (Details) (USD $)	6 Months Ended		12 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Dec. 31, 2011	May 08, 2014	Dec. 31, 2013
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Percentage of Net Sales			10.00%
License Costs			$ 0.30
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Warrant Derivative Liabilities	0				23,200
Acquisition-related contingent consideration	20,640,000			10,800,000	9,450,000
Accrued Liabilities and Other Liabilities	20,640,000				9,473,200
Warrants Issued During Period, Value	0	71,600
Business Combination, Consideration Transferred, Liabilities Incurred	10,790,000
Change in acquisition-related contingent consideration	400,000	0
Fair Value, Option, Changes in Fair Value, Gain (Loss)	400,000
Expiration	(23,200)
Warrant Derivative Liabilities	0				23,200
Warrants
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Warrants Issued During Period, Value	0
Fair Value Adjustment of Warrants	0
Expiration	(23,200)
Contingent Consideration Classified as Equity [Member]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Acquisition-related contingent consideration	20,640,000				9,450,000
Business Combination, Contingent Consideration Arrangements, Basis for Amount	10790.0
Change in acquisition-related contingent consideration	400,000
Expiration	$ 0

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Accrued Liabilities Accrued Liabilities (Tables)

6 Months Ended

Jun. 30, 2014

Accrued Liabilities [Abstract]

Schedule of Accrued Liabilities [Table Text Block]

Accrued liabilities as of June 30, 2014 and December 31, 2013 were as follows (in thousands):

	June 30, 2014		December 31, 2013
Salaries, employee benefits and related taxes	$	1,443.2	$	2,325.8
Professional fees	651.7		544.8
License fees	100.0		500.0
Other	392.4		647.4
	$	2,587.3	$	4,018.0

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Shareholders' Equity (Tables)

6 Months Ended

Jun. 30, 2014

Shareholders’ Equity [Abstract]

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

The following table summarizes the activity for stock options and warrants for the six months endedJune 30, 2014:

	Stock Options							Warrants
	Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)	Aggregate Intrinsic Value (In Thousands)		Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)	Aggregate Intrinsic Value (In Thousands)
Outstanding at December 31, 2013	2,932,191		$	11.19	6.8	$	1,658.1	4,898,266		$	16.50	2.6	$	1,811.0
Changes during the period:
Granted	1,653,325		$	7.05				2,722		$	12.26
Exercised	(41,136	)	$	5.60				(265,250	)	$	5.18
Forfeited	(189,454	)	$	6.34				(100,108	)	$	70.00
Expired	(150,656	)	$	15.78				(911,674	)	$	23.97
Outstanding at June 30, 2014	4,204,270		$	9.67	7.6	$	1,657.4	3,623,956		$	13.96	2.6	$	1,080.2
Vested at June 30, 2014 or expected to vest in the future	3,891,887		$	9.86	7.4	$	1,592.8	3,623,956		$	13.96	2.6	$	1,080.2
Vested at June 30, 2014	2,533,802		$	11.16	6.5	$	1,123.2	3,611,456		$	13.98	2.6	$	1,080.2

Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]

During the six months endedJune 30, 2014 and 2013, the Company issued warrants for services as follows ($ in thousands, except share data):

	Six Months Ended June 30,
	2014		2013
Number of Common Stock Purchase Warrants Issued	—		20,407
Value of Common Stock Purchase Warrants Issued	$	—	$	71.6

Restricted Stock [Table Text Block]

During the six months endedJune 30, 2014 and 2013, the Company issued restricted stock for services as follows ($ in thousands, except share data):

	Six Months Ended June 30,
	2014		2013
Number of Restricted Stock Issued	456,709		304,402
Value of Restricted Stock Issued	$	3,389.7	$	1,858.3

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The Business

6 Months Ended

Jun. 30, 2014

The Business [Abstract]

Nature of Operations [Text Block]

The Business

Overview

NeoStem, Inc. (“we,” “NeoStem” or the “Company”) is a leader in the emerging cellular therapy industry. We are pursuing the preservation and enhancement of human health globally through the development of cell based therapeutics that prevent, treat or cure disease. We have multiple cell therapy platforms that work to address the pathology of disease using a person's own cells to amplify the body's natural repair mechanisms including enhancing the destruction of cancer initiating cells, repairing and replacing damaged or aged tissue, cells and organs and restoring their normal function. We believe that cell therapy will play a large role in changing the natural history of diseases as more breakthrough therapies are developed, ultimately lessening the overall burden of disease on patients and their families as well as the economic burden that these diseases impose upon modern society.

Our business includes the development of novel proprietary cell therapy products, as well as a revenue-generating contract development and manufacturing service business that we leverage for the development of our therapeutics while providing service to other companies in the cell therapy industry. The combination of our own therapeutic development business and a revenue-generating service provider business provides the Company with unique capabilities for cost effective in-house product development and immediate revenue and future cash flow to help underwrite our internal development programs. This business model enables the Company to be opportunistic in growing its pipeline as evidenced by the Company's acquisition in May 2014 of California Stem Cell, Inc. ("CSC"), a cell biotechnology corporation that is developing cellular immunotherapies for cancer, an area we view to be one of the most promising sub-sectors in biotechnology. The lead product candidate in its immunotherapy pipeline is NBS20, also referred to as DC/TC (dendritic cell/tumor cell), and is targeting malignant melanoma initiating cells. This immunotherapy designed to treat Stage IV or recurrent Stage III metastatic melanoma, which has been granted fast track and orphan designation by the Food and Drug Administration ("FDA"), also has a Phase 3 protocol that is the subject of a Special Protocol Assessment ("SPA"). The SPA, indicates that the FDA is in agreement with the design, clinical endpoints, and planned clinical analyses of the Phase 3 trial that would serve as the basis for a Biologics License Application ("BLA") that would be filed with the FDA requesting marketing approval of this therapeutic candidate. This protocol calls for enrolling 250 evaluable patients and is expected to be initiated later in 2014. We are evaluating other clinical indications into which we may advance this program, including liver, ovarian and lung cancers.

We are also currently developing therapies to address ischemia through utilizing CD34 cells. Ischemia occurs when the supply of oxygenated blood in the body is restricted. We seek to reverse this restriction through the development and formation of new blood vessels. NBS10, also referred to as AMR-001, is our most clinically advanced product candidate in our ischemic repair program and is being developed to treat damaged heart muscle following an acute myocardial infarction (heart attack) ("AMI"). In December 2013, the Company completed enrollment in its PreSERVE AMI study. PreSERVE AMI is a randomized, double-blinded, placebo-controlled Phase 2 clinical trial testing NBS10, an autologous (donor and recipient are the same) adult stem cell product for the treatment of patients with left ventricular dysfunction following acute ST segment elevation myocardial infarction (STEMI). The last patient in the trial was infused in December 2013 and the last patient six-month follow-up occurred in June 2014. Once the primary end point six-month data is collected, the data set will be locked and analysis will begin.   An abstract for the PreSERVE AMI study has been accepted for presentation at the American Heart Association's Scientific Sessions being held November 15-19, 2014 although we anticipate results of the study will be released earlier. If approved by the FDA and/or other worldwide regulatory agencies following successful completion of further trials, NBS10 would address a significant medical need for which there is currently no effective treatment, potentially improving longevity and quality of life for those suffering a STEMI, and positioning the Company to capture a meaningful share of this worldwide market. We are evaluating other clinical indications into which we may advance this program, including traumatic brain injury ("TBI"), congestive heart failure ("CHF"), and critical limb ischemia ("CLI").

Another platform technology we are developing utilizes T Regulatory Cells ("Tregs") to treat diseases caused by imbalances in an individual's immune system.  Collaborating with the University of California, San Francisco, we are utilizing the technology platform of our majority-owned subsidiary, Athelos Corporation ("Athelos"), to restore immune balance by enhancing Treg cell number and function.  Tregs are a natural part of the human immune system and regulate the activity of T effector cells, the cells that are responsible for protecting the body from viruses and other foreign antigens. When Tregs function properly, only harmful foreign materials are attacked by T effector cells. In autoimmune disease it is thought that deficient Treg activity permits the T effector cells to attack the body's own tissues, while in allergic diseases, like asthma, it is though that the immune system overreacts to harmless foreign substances. We plan to initiate in 2014, subject to review and approval of the protocols by the appropriate regulatory authorities, a Phase 2 study of NBS03D, a Treg based therapeutic, in the treatment of type 1 diabetes, and a Phase 1 study in Canada of NBS03A, a Treg based therapeutic, in support of our steroid resistant asthma development program.

Pre-clinical assets include our VSEL ^TM (Very Small Embryonic Like) Technology regenerative medicine platform. Regenerative medicine holds the promise of improving clinical outcomes and reducing overall  healthcare costs.  We are working on a Department of Defense funded study of VSELs^TM for the treatment of chronic wounds. Other preclinical work with VSELs^TM includes exploring macular degeneration as a target indication.

Progenitor Cell Therapy, LLC ("PCT") is a contract manufacturer in the cellular therapy industry that generates revenue. This wholly owned subsidiary, which we acquired in 2011, is an industry leader in providing high quality manufacturing capabilities and support to developers of cell-based therapies to enable them to improve efficiencies and profitability and reduce the capital investment required for their own development activities. Since its inception more than 15 years ago, PCT has provided pre-clinical and clinical current Good Manufacturing Practice (“cGMP”) development and manufacturing services to more than 100 clients. PCT has experience advancing regenerative medicine product candidates from product inception through rigorous quality standards all the way through to human testing, BLA filing and FDA product approval. PCT's core competencies in the cellular therapy industry include manufacturing of cell therapy-based products, engineering and innovation services, product and process development, cell and tissue processing, regulatory support, storage, distribution and delivery and consulting services. PCT has two cGMP, state-of-the art cell therapy research, development, and manufacturing facilities in New Jersey and California, serving the cell therapy community with integrated and regulatory compliant distribution capabilities. The Company is pursuing commercial expansion of our manufacturing operations both in the U.S. and internationally. Additionally, with our acquisition of CSC in Irvine, California, we are now in a position to leverage NeoStem Oncology's expertise in immunotherapy and advance our platform technology, as well as the technologies of PCT's client base.

Strategic acquisitions have been the cornerstone of NeoStem’s growth and have been selected in order to provide value to stockholders by taking advantage of the infrastructure we have created which includes strong development, regulatory and manufacturing expertise. By adding NBS20, our DC/TC product candidate and a late stage novel proprietary cancer cell therapy into our pipeline, we look to further advance towards our goal of delivering transformative cell based therapies to the market to help patients suffering from life-threatening medical conditions. Coupled with our strong manufacturing capability, we believe the stage is set for us to realize meaningful clinical development and manufacturing efficiencies, further positioning NeoStem to lead the cell therapy industry.

Basis of Presentation

The accompanying unaudited Consolidated Financial Statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“generally accepted accounting principles”) for interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation S-X of the Securities and Exchange Commission for interim financial information. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, the accompanying Consolidated Financial Statements of the Company and its subsidiaries, which are unaudited, include all normal and recurring adjustments considered necessary to present fairly the Company’s financial position as of June 30, 2014 and the results of its operations and its cash flows for the periods presented. The unaudited consolidated financial statements herein should be read together with the historical consolidated financial statements of the Company for the years ended December 31, 2013 and 2012 included in our Annual Report on Form 10-K for the year ended December 31, 2013. Operating results for the six months endedJune 30, 2014 are not necessarily indicative of the results that may be expected for the year ending December 31, 2014.

Use of Estimates

The preparation of financial statements in conformity with generally accepted accounting principles in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the consolidated financial statements. Estimates also affect the reported amounts of revenues and expenses during the reporting period. Accordingly, actual results could differ from those estimates.

Reclassifications

Certain reclassifications have been made to the Consolidated Financial Statements and Notes to the Consolidated Financial Statements for the three and six months endedJune 30, 2013 to conform to the presentation for the three and six months endedJune 30, 2014.

Principles of Consolidation

The Consolidated Financial Statements include the accounts of NeoStem, Inc. and its wholly owned and partially owned subsidiaries and affiliates as listed below.

Entity	Percentage of Ownership	Location
NeoStem, Inc.	Parent  Company	United States of America
NeoStem Therapies, Inc.	100%	United States of America
Stem Cell Technologies, Inc.	100%	United States of America
Amorcyte, LLC	100%	United States of America
Progenitor Cell Therapy, LLC (PCT)	100%	United States of America
NeoStem Family Storage, LLC	100%	United States of America
Athelos Corporation (1)	90%	United States of America
PCT Allendale, LLC	100%	United States of America
NeoStem Oncology, LLC (2)	100%	United States of America

(1) Pursuant to the Stock Purchase Agreement signed in March 2011, our initial ownership in Athelos was 80.1%, and Becton Dickinson's ("BD") initial minority ownership was 19.9%. Per the Agreement, BD will be diluted based on new investment in Athelos by us (subject to certain anti-dilution provisions). As of June 30, 2014, BD's ownership interest in Athelos was decreased to 10.0%, and our ownership increased to 90.0%. As a result in the change in ownership, approximately $0.1 million was transferred from additional paid in capital to non-controlling interests.

(2) On May 8, 2014, NeoStem acquired CSC, now known as NeoStem Oncology, LLC (see Note 3, Acquisition). Accordingly, the operating results of NeoStem Oncology, LLC prior to May 8, 2014 are not included in the Company's consolidated operations and cash flows.

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Share-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2014

Share-based Compensation [Abstract]

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

The following table summarizes the components of share-based compensation expense for the three and six months endedJune 30, 2014 and 2013 (in thousands):

	Three Months Ended June 30,				Six Months Ended June 30,
	2014		2013		2014		2013
Cost of goods sold	$	98.5	$	58.5	$	236.6	$	145.0
Research and development	371.6		129.8		848.4		347.1
Selling, general and administrative	1,289.6		907.4		4,568.5		2,822.1
Total share-based compensation expense	$	1,759.7	$	1,095.7	$	5,653.5	$	3,314.2

Disclosure of Share-based Compensation Arrangements by Share-based Payment Award [Table Text Block]

Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at June 30, 2014 were as follows (dollars in thousands):

	Stock Options		Warrants		Restricted Stock
Unrecognized compensation cost	$	6,814.9	$	33.4	$	262.9
Expected weighted-average period in years of compensation cost to be recognized	5.02		1.05		0.19

Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value [Table Text Block]

Total fair value of shares vested and the weighted average estimated fair values of shares granted for the six months endedJune 30, 2014 and 2013 were as follows (dollars in thousands):

	Stock Options				Warrants
	Six Months Ended June 30,				Six Months Ended June 30,
	2014		2013		2014		2013
Total fair value of shares vested	$	2,552.2	$	1,646.3	$	15.0	$	80.9
Weighted average estimated fair value of shares granted	$	4.92	$	4.58	$	—	$	3.51

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Available-for-Sale-Securities Available-for-sale Securities by Contractual Maturity (Details) (USD $)	Jun. 30, 2014
Available-for-sale Securities [Abstract]
Less than one year, Amortized Cost	$ 28,376,300
Less than one year, Fair Value	28,377,300
Amortized Cost	28,376,300
Estimated Fair Value	$ 28,377,300

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Shareholders' Equity Stock options and warrants (Details) (USD $)	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Dec. 31, 2013
Stock Options and Warrants [Line Items]
Stock Issued During Period, Shares, Other	0	20,407
Warrants Issued During Period, Value	$ 0	$ 71,600
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value	1,657,400	1,658,100
Common Stock Warrants, Shares	3,623,956		4,898,266
Weighted Average Exercise Price, Warrants Outstanding	13.96		16.50
Weighted Average Remaining Contractual Term warrant outstanding	2 years 7 months 17 days	2 years 7 months 17 days
Aggregate Intrinsic Value, Warrants Outstanding	1,080,200	1,811,000
Warrants Granted	2,722
Weighted Average Exercise Price, Warrants Granted	$ 12.26
Warrants Exercised	(265,250)
Weighted Average Exercise Price, Warrants Exercised	$ 5.18
Warrants Expired	(100,108)
Weighted Average Exercise Price, Warrants Expired	$ 70.00
Warrants Canceled	(911,674)
Weighted Average Exercise Price, Warrants Canceled	$ 23.97
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value	1,592,800
shares, vested and expected to vest	3,623,956
Weighted Average Exercise Price, Warrants vested & expected to vest	13.96
Aggregate Intrinsic Value, Warrants vested and expected to vest	1,080,200
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value	1,123,200
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number	3,611,456
Weighted Average Exercise Price, Warrants Exercisable	13.98
weighted Average Remaining Contractual Term, warrants vested	2 years 7 months 13 days
Aggregate Intrinsic Value, Warrants vested	$ 1,080,200
Warrants
Stock Options and Warrants [Line Items]
Weighted average estimated fair value of shares granted	$ 0.00		$ 3.51
US Equity Plan [Member]
Stock Options and Warrants [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number	4,204,270		2,932,191
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price	$ 9.67		$ 11.19
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term	7 years 6 months 26 days	6 years 9 months 22 days
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures	1,653,325
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price	$ 7.05
Stock Options Exercised	(41,136)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price	$ 5.60
Stock Options Expired	(189,454)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price	$ 6.34
Stock Options Forfeited	(150,656)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price	$ 15.78
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number	3,891,887
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price	$ 9.86
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term	7 years 4 months 28 days
Weighted Average Remaining Contractual Term, Warrants Vested and Expect to Vest	2 years 7 months 17 days
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number	2,533,802
Weighted average estimated fair value of shares granted	$ 11.16
Options, Vested, weighted Average Remaining Contractual Term	6 years 6 months 18 days
Minimum [Member]
Stock Options and Warrants [Line Items]
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Upper Range Limit	$ 5.20
Maximum [Member]
Stock Options and Warrants [Line Items]
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Upper Range Limit	$ 6.20

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Consolidated Balance Sheets (USD $)	Jun. 30, 2014	Dec. 31, 2013
Current Assets
Cash and cash equivalents	$ 32,865,071	$ 46,133,759
Marketable securities	920,827	0
Accounts receivable, net of allowance for doubtful accounts of $389,809 and $391,829 at June 30, 2014 and December 31, 2013, respectively	2,510,114	1,860,835
Inventory	2,033,011	1,270,223
Prepaid expenses and other current assets	2,525,402	1,561,933
Total current assets	40,854,425	50,826,750
Property, plant and equipment, net	15,639,291	12,844,216
Goodwill	26,079,536	11,117,770
Intangible assets, net	49,363,012	13,875,617
Other assets	1,459,627	1,151,729
Assets, Total	133,395,891	89,816,082
Current Liabilities
Accounts payable	5,481,229	3,354,908
Accrued liabilities	2,587,328	4,018,026
Notes payable	794,236	381,097
Mortgages payable	218,988	213,112
Derivative liabilities	0	23,175
Unearned revenues	2,830,546	1,816,601
Total current liabilities	11,912,327	9,806,919
Long-term Liabilities
Deferred income taxes	18,983,288	4,379,226
Notes payable	1,015,681	531,164
Mortgages payable	2,912,282	3,023,609
Acquisition-related contingent consideration	20,640,000	9,450,000
Other long-term liabilities	635,008	598,729
Liabilities	56,098,586	27,789,647
Commitments and Contingencies
Stockholders' Equity
Preferred stock, authorized, 20,000,000 shares; Series B convertible redeemable preferred stock liquidation value, 0.01 share of common stock, $.01 par value; 825,000 shares designated; issued and outstanding, 10,000 shares at June 30, 2014 and December 31, 2013	100	100
Common stock, $.001 par value, authorized 500,000,000 shares; issued and outstanding, 34,939,223 and 27,196,537 shares, at June 30, 2014 and December 31, 2013, respectively	34,939	27,197
Additional paid-in capital	341,369,613	299,594,525
Treasury stock, at cost	(705,742)	(705,742)
Accumulated deficit	(262,660,679)	(236,373,605)
Accumulated other comprehensive income	998	0
Total NeoStem, Inc. stockholders' equity	78,039,229	62,542,475
Noncontrolling interests	(741,924)	(516,040)
Total equity	77,297,305	62,026,435
Liabilities and Equity, Total	$ 133,395,891	$ 89,816,082

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Goodwill and Other Intangible Assets Intangible Assets and Related Accumulated Amortization (Details) (USD $)				6 Months Ended		6 Months Ended		6 Months Ended		6 Months Ended		6 Months Ended				6 Months Ended
	Jun. 30, 2014	May 08, 2014	Dec. 31, 2013	Jun. 30, 2014 Customer Lists [Member]	Dec. 31, 2013 Customer Lists [Member]	Jun. 30, 2014 Manufacturing Technology [Member]	Dec. 31, 2013 Manufacturing Technology [Member]	Jun. 30, 2014 Trade Names [Member]	Dec. 31, 2013 Trade Names [Member]	Jun. 30, 2014 In Process R and D [Member]	Dec. 31, 2013 In Process R and D [Member]	Jun. 30, 2014 VSEL Patent Rights [Member]	Dec. 31, 2013 VSEL Patent Rights [Member]	Jun. 30, 2014 NeoStem, Inc. [Member]	Dec. 31, 2013 NeoStem, Inc. [Member]	Jun. 30, 2014 NeoStem Oncology [Member]
Goodwill [Roll Forward]
Goodwill	$ 26,079,536	$ 14,961,900	$ 11,117,770											$ 26,079.5	$ 11,117.7
Goodwill, Acquired During Period																14,961.8
Goodwill	26,079,536	14,961,900	11,117,770											26,079.5	11,117.7
Finite-Lived Intangible Assets, Gross	51,559,000		15,769,000	1,000,000	1,000,000	3,900,000	3,900,000	800,000	800,000	45,190,000	9,400,000	669,000	669,000
Finite-Lived Intangible Assets, Accumulated Amortization	(2,196,000)		(1,893,400)	(345,100)	(295,100)	(1,345,900)	(1,150,900)	(276,100)	(236,100)	0	0	(228,900)	(211,300)
Finite-Lived Intangible Assets, Future Amortization Expense	$ 49,363,000		$ 13,875,600	$ 654,900	$ 704,900	$ 2,554,100	$ 2,749,100	$ 523,900	$ 563,900	$ 45,190,000	$ 9,400,000	$ 440,100	$ 457,700
Finite Lived Intangible Assets, Useful Life [String]										Indefinite
Finite-Lived Intangible Assets, Useful Life				10 years		10 years		10 years				19 years

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Consolidated Statements of Equity (USD $)	Total	Total NeoStem, Inc. Shareholders' Equity [Member]	Preferred Stock [Member] Series B Preferred Stock [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Income (Loss) [Member]	Accumulated Deficit [Member]	Treasury Stock [Member]	Noncontrolling Interest [Member]
Beginning Balance at Dec. 31, 2012	$ 32,820,159	$ 33,177,129	$ 100	$ 16,375	$ 231,218,615	$ 0	$ (197,392,361)	$ (665,600)	$ (356,970)
Beginning Balance (shares) at Dec. 31, 2012			10,000	16,375,365
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(17,489,971)	(17,375,935)					(17,375,935)		(114,036)
Share-based compensation (in shares)				304,402
Share-based compensation	3,314,197	3,314,197		304	3,313,893
Stock Issued During Period, Shares, New Issues				2,883,847
Net proceeds from issuance of common stock	14,248,148	14,248,148		2,884	14,245,264
Proceeds from exercise of options	0
Proceeds from warrant exercise (in shares)				20,761
Stock Issued During Period, Value, Warrant Exercises	105,881	105,881		21	105,860
Warrant Inducements	6,239	6,239			6,239
Ending Balance at Jun. 30, 2013	32,992,175	33,463,181	100	19,584	248,877,393	0	(214,768,296)	(665,600)	(471,006)
Ending Balance (shares) at Jun. 30, 2013			10,000	19,584,375
Beginning Balance at Dec. 31, 2013	62,026,435	62,542,475	100	27,197	299,594,525	0	(236,373,605)	(705,742)	(516,040)
Beginning Balance (shares) at Dec. 31, 2013			10,000	27,196,537
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(26,599,576)	(26,287,074)					(26,287,074)		(312,502)
Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax	998	998				998
Share-based compensation (in shares)				456,709
Share-based compensation	5,653,451	5,653,451		457	5,652,994
Stock Issued During Period, Shares, New Issues				1,650,081
Net proceeds from issuance of common stock	10,149,438	10,149,438		1,650	10,147,788
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period				41,136
Proceeds from exercise of options	230,183	230,183		41	230,142
Proceeds from warrant exercise (in shares)				265,250
Stock Issued During Period, Value, Warrant Exercises	1,373,925	1,373,925		264	1,373,661
Stock Issued During Period, Shares, Acquisitions				5,329,510
Stock Issued During Period, Value, Acquisitions	24,462,451	24,462,451		5,330	24,457,121
Change in Ownership in Subsidiary	0	(86,618)			(86,618)				86,618
Ending Balance at Jun. 30, 2014	$ 77,297,305	$ 78,039,229	$ 100	$ 34,939	$ 341,369,613	$ 998	$ (262,660,679)	$ (705,742)	$ (741,924)
Ending Balance (shares) at Jun. 30, 2014			10,000	34,939,223

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The Business Principal of consolidation (Details)	6 Months Ended
	Jun. 30, 2014
NeoStem, Inc. [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Minority Interest Ownership Percentage By Parent [String]	Parent  Company
NeoStem Therapies, Inc [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary, Ownership Interest by Parent	100.00%
Stem Cell Technologies, Inc [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary, Ownership Interest by Parent	100.00%
Amorcyte, LLC [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary, Ownership Interest by Parent	100.00%
China Biopharmaceuticals Holdings, Inc. [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary of Limited Liability Company or Limited Partnership, Ownership Interest	100.00%
Suzhou Erye Pharmaceuticals Company Ltd. [Member] | CHINA
Schedule of Subisidiary [Line Items]
Subsidiary of Limited Liability Company or Limited Partnership, Ownership Interest	51.00%
Progenitor Cell Therapy, LLC [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary, Ownership Interest by Parent	100.00%
NeoStem Family Storage, LLC [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary of Limited Liability Company or Limited Partnership, Ownership Interest	100.00%
Minority Interest Ownership Percentage By Parent [String]	1
Athelos Corporation [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary of Limited Liability Company or Limited Partnership, Ownership Interest	90.00%
Minority Interest Ownership Percentage By Parent [String]	0.90
PCT Allendale, LLC [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary of Limited Liability Company or Limited Partnership, Ownership Interest	100.00%
Minority Interest Ownership Percentage By Parent [String]	1
NeoStem Oncology [Member] | UNITED STATES
Schedule of Subisidiary [Line Items]
Subsidiary, Ownership Interest by Parent	100.00%

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Commitments and Contingencies

6 Months Ended

Jun. 30, 2014

Commitments and Contingencies [Abstract]

Commitments and Contingencies [Text Block]

Commitments and Contingencies

Lease Commitments

The Company leases offices, of which certain have escalation clauses and renewal options, and also leases equipment under certain noncancelable operating leases that expire from time to time through 2018. In January 2014, the Company signed a new lease for additional space at its current executive offices at 420 Lexington Avenue, New York, NY 10170. The new lease is believed to provide sufficient space for the near future and shall extend through 2018. This property is used as the Company's corporate headquarters. In connection with the acquisition of CSC on May 8, 2014, the Company assumed a facility lease in Irvine, California, with a termination at the end of 2017.

A summary of future minimum rental payments required under operating leases that have initial or remaining terms in excess of one year as of June 30, 2014 are as follows (in thousands):  

Years ended	Operating Leases
2014	$	675.3
2015	1,160.5
2016	997.9
2017	697.8
2018	5.9
Total minimum lease payments	$	3,537.4

Expense incurred under operating leases was approximately $0.3 million and $0.3 million for the three months endedJune 30, 2014 and 2013, respectively. Expense incurred under operating leases was approximately $0.5 million and $0.6 million for the six months endedJune 30, 2014 and 2013, respectively.

Contingencies

Under license agreements with third parties the Company is typically required to pay maintenance fees, make milestone payments and/or pay other fees and expenses and pay royalties upon commercialization of products. The Company also sponsors research at various academic institutions, which research agreements generally provide us with an option to license new technology discovered during the course of the sponsored research.

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Summary of Significant Accounting Policies (Details) (USD $) In Millions, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Summary of Significant Accounting Policies [Abstract]
Clinical Services Reimbursement	$ 1.1	$ 0.4	$ 1.8	$ 0.8

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The Business (Tables)

6 Months Ended

Jun. 30, 2014

The Business [Abstract]

Subsidiary [Table Text Block]

.

Entity	Percentage of Ownership	Location
NeoStem, Inc.	Parent  Company	United States of America
NeoStem Therapies, Inc.	100%	United States of America
Stem Cell Technologies, Inc.	100%	United States of America
Amorcyte, LLC	100%	United States of America
Progenitor Cell Therapy, LLC (PCT)	100%	United States of America
NeoStem Family Storage, LLC	100%	United States of America
Athelos Corporation (1)	90%	United States of America
PCT Allendale, LLC	100%	United States of America
NeoStem Oncology, LLC (2)	100%	United States of America

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Consolidated Statements of Cash Flows (USD $)	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013
Cash flows from operating activities:
Net loss	$ (26,599,576)	$ (17,489,971)
Adjustments to reconcile net loss to net cash used in operating activities:
Equity-based compensation expense	5,653,451	3,314,197
Depreciation and amortization	987,698	832,920
Changes in fair value of derivative liability	(23,175)	(68,556)
Change in acquisition-related contingent consideration	400,000	0
Bad debt recovery	(2,020)	(7,178)
Deferred income taxes	94,796	447,568
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(944,297)	(190,150)
Accounts receivable	(602,132)	359,163
Inventory	(762,788)	1,081,060
Unearned revenues	1,013,946	(1,106,299)
Other assets	(106,909)	(25,805)
Accounts payable, accrued expenses and other liabilities	(1,615,234)	(272,718)
Net cash used in operating activities	(22,506,240)	(13,125,769)
Cash flows from investing activities:
Net cash received in acquisitions	50,894	0
Purchase of marketable securities	(919,829)	0
Acquisition of property and equipment	(2,439,266)	(268,535)
Net cash used in investing activities	(3,308,201)	(268,535)
Cash flows from financing activities:
Proceeds from exercise of options	230,183	0
Proceeds from exercise of warrants	1,373,925	105,881
Net proceeds from issuance of common stock	10,149,439	14,248,148
Repayment of mortgage loan	(105,450)	(93,070)
Proceeds from notes payable	1,340,981	221,218
Repayment of notes payable	(443,325)	(96,608)
Payment for warrant inducement	0	(6,239)
Net cash provided by financing activities	12,545,753	14,379,330
Net (decrease) increase in cash and cash equivalents	(13,268,688)	985,026
Cash and cash equivalents at beginning of period	46,133,759	13,737,452
Cash and cash equivalents at beginning of period	32,865,071	14,722,478
Cash paid during the period for:
Interest	196,200	126,000
Taxes	0	0
Common stock and contingent consideration issued in merger	$ 35,252,451	$ 0

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Consolidated Balance Sheets (Parentheticals) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Preferred Stock, Shares Outstanding	10,000	10,000
Common Stock, Par Value	$ 0.001	$ 0.001
Accounts receivable trade, net of allowance for doubtful accounts	$ 389,809	$ 391,829
Preferred Stock, authorized	20,000,000	20,000,000
Common stock, outstanding	34,939,223	27,196,537
Common Stock, authorized	500,000,000	500,000,000
Common Stock, Shares, Issued	34,939,223	27,196,537
Preferred stock, shares designated	825,000	825,000
Preferred stock, issued	10,000	10,000
Preferred stock, Series B convertible redeemable preferred stock liquidation value, share of common stock	0.01	0.01
Preferred stock, par value	$ 0.01	$ 0.01

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Debt

6 Months Ended

Jun. 30, 2014

Debt [Abstract]

Debt Disclosure [Text Block]

Debt

Notes Payable

As of June 30, 2014 and December 31, 2013, the Company had notes payable of approximately $1.8 million and $0.9 million, respectively. The notes relate to certain insurance policies and equipment financings, require monthly payments, and mature within one to three years.

Mortgages Payable

In October 2007, PCT issued a note to borrow $3.1 million (the “First Mortgage”) in connection with its $3.8 million purchase of condominium units in an existing building in Allendale, New Jersey (the “Property”). The First Mortgage is payable in 239 consecutive monthly payments of principal and interest, based on a 20 year amortization schedule; and one final payment of all outstanding principal plus accrued interest then due. The current monthly installment is $20,766, which includes interest at an initial rate of 5.00%; the interest rate and monthly installments payments are subject to adjustment on October 1, 2017. On that date, upon prior written notice, the lender has the option to declare the entire outstanding principal balance, together with all outstanding interest, due and payable in full. The First Mortgage is secured by substantially all of the assets of PCT, including a first mortgage on the Property and assignment of an amount approximately equal to eighteen months debt service held in escrow. The Note matures on October 1, 2027 if not called by the lender on October 1, 2017. The First Mortgage had previously been subject to certain debt service coverage and total debt to tangible net worth financial covenant ratios measured semi-annually. The outstanding balance was approximately $2.4 million and $2.5 million at June 30, 2014 and December 31, 2013, respectively, of which $130,000 is payable within twelve months as of June 30, 2014.

In December 2010 PCT Allendale, a wholly-owned subsidiary of PCT, entered into a note for a second mortgage in the amount of $1.0 million (the "Second Mortgage") on the Allendale Property with TD Bank, N.A. The initial guarantors of the Second Mortgage were PCT, DomaniCell (a wholly-owned subsidiary of PCT, now known as NeoStem Family Storage, LLC), Regional Cancer Care Associates LLC and certain of its partners. The Second Mortgage had been subject to an annual financial covenant starting December 31, 2011. The Second Mortgage is for 124 months at a fixed rate of 6% for the first 64 months. The loan is callable for a certain period prior to the interest reset date. The outstanding balance was approximately $0.7 million and $0.8 million at June 30, 2014 and December 31, 2013, respectively, of which $89,000 is payable within twelve months as of June 30, 2014.

In December 2013, the Company modified both the First Mortgage and Second Mortgage with TD Bank, N.A., whereby (i) prior debt service coverage and total debt to tangible net worth financial covenant ratios were replaced with a minimum unencumbered liquidity covenant, and (ii) prior guarantors were released (see Note 14) and replaced with NeoStem, PCT, and NeoStem Family Storage. The Company is in compliance with the new minimum unencumbered liquidity covenant.

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Document and Entity Information Document	6 Months Ended
	Jun. 30, 2014	Aug. 07, 2014
Document Information [Line Items]
Entity Registrant Name	NeoStem, Inc.
Entity Central Index Key	0000320017
Current Fiscal Year End Date	--12-31
Entity Filer Category	Accelerated Filer
Document Type	10-Q
Document Period End Date	Jun. 30, 2014
Document Fiscal Year Focus	2014
Document Fiscal Period Focus	Q2
Amendment Flag	false
Entity Common Stock, Shares Outstanding		35,252,041

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Shareholders' Equity

6 Months Ended

Jun. 30, 2014

Shareholders’ Equity [Abstract]

Stockholders' Equity Note Disclosure [Text Block]

Shareholders' Equity

Reverse Stock Split

On June 28, 2013, pursuant to prior shareholder authorization, the Company’s board of directors unanimously approved a 1-for-10 reverse stock split of the Company’s common stock, which the Company effected on July 16, 2013. All share and per share amounts of common stock, options and warrants in the accompanying financial statements have been restated for all periods to give retroactive effect to the reverse stock split. The shares of common stock retained a par value of $0.001 per share. Accordingly, the stockholders’ deficit reflects the reverse stock split by reclassifying from “common stock” to “additional paid-in capital” an amount equal to the par value of the decreased shares resulting from the reverse stock split.

Equity Issuances

In September 2011, the Company entered into a common stock purchase agreement (the “Initial Purchase Agreement”) with Aspire Capital Fund, LLC, an Illinois limited liability company (“Aspire Capital”), which provided that Aspire Capital was committed to purchase up to an aggregate of $20.0 million worth of shares of the Company’s common stock over the 24-month term. In August, 2012, the Initial Purchase Agreement was extended for an additional 24-month term through September 2015. During the three months ended March 31, 2014, the Company issued 0.8 million shares of Common Stock under the provisions the Initial Purchase Agreement with Aspire for gross proceeds of approximately $5.6 million. As of March 31, 2014, the full $20.0 million worth of shares of the Company's stock had been issued under the Initial Purchase Agreement.

In March 2014, the Company entered into a new common stock purchase agreement (the “Purchase Agreement”) with Aspire Capital, which provides that, subject to certain terms and conditions, Aspire Capital is committed to purchase up to an aggregate of $30.0 million worth of shares of the Company’s common stock over the 24-month term. At the Company’s discretion, it may present Aspire Capital with purchase notices from time to time to purchase the Company’s common stock, provided certain price and other requirements are met. The purchase price for the shares of stock was based upon one of two formulas set forth in the Purchase Agreement depending on the type of purchase notice the Company submits to Aspire Capital, and is based on market prices of the Company’s common stock (in the case of regular purchases) or a discount of 5% applied to volume weighted average prices (in the case of VWAP purchases), in each case as determined by parameters defined in the Purchase Agreement. As consideration for entering into the Purchase Agreement, we issued 150,000 shares of our common stock to Aspire Capital. During the six months endedJune 30, 2014, the Company issued 0.7 million shares of Common Stock under the provisions the Purchase Agreement with Aspire for gross proceeds of approximately $4.4 million.

Option Exercises

During the six months ended ended June 30, 2014, option holders exercised an aggregate of 41,136 options at exercise prices between of $5.20 and $6.20 per share for gross proceeds of approximately $0.2 million.

Warrant Exercises

During the six months ended ended June 30, 2014, warrant holders exercised an aggregate of 265,250 warrants at exercise price between $5.10 and $14.50 per share for gross proceeds of approximately $1.4 million.

Stock Options and Warrants

The following table summarizes the activity for stock options and warrants for the six months endedJune 30, 2014:

	Stock Options							Warrants
	Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)	Aggregate Intrinsic Value (In Thousands)		Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (Years)	Aggregate Intrinsic Value (In Thousands)
Outstanding at December 31, 2013	2,932,191		$	11.19	6.8	$	1,658.1	4,898,266		$	16.50	2.6	$	1,811.0
Changes during the period:
Granted	1,653,325		$	7.05				2,722		$	12.26
Exercised	(41,136	)	$	5.60				(265,250	)	$	5.18
Forfeited	(189,454	)	$	6.34				(100,108	)	$	70.00
Expired	(150,656	)	$	15.78				(911,674	)	$	23.97
Outstanding at June 30, 2014	4,204,270		$	9.67	7.6	$	1,657.4	3,623,956		$	13.96	2.6	$	1,080.2
Vested at June 30, 2014 or expected to vest in the future	3,891,887		$	9.86	7.4	$	1,592.8	3,623,956		$	13.96	2.6	$	1,080.2
Vested at June 30, 2014	2,533,802		$	11.16	6.5	$	1,123.2	3,611,456		$	13.98	2.6	$	1,080.2

During the six months endedJune 30, 2014 and 2013, the Company issued warrants for services as follows ($ in thousands, except share data):

	Six Months Ended June 30,
	2014		2013
Number of Common Stock Purchase Warrants Issued	—		20,407
Value of Common Stock Purchase Warrants Issued	$	—	$	71.6

Restricted Stock

During the six months endedJune 30, 2014 and 2013, the Company issued restricted stock for services as follows ($ in thousands, except share data):

	Six Months Ended June 30,
	2014		2013
Number of Restricted Stock Issued	456,709		304,402
Value of Restricted Stock Issued	$	3,389.7	$	1,858.3

The weighted average estimated fair value of restricted stock issued for services in the six months endedJune 30, 2014 and 2013 was $7.42 and $6.10 per share, respectively. The fair value of the restricted stock was determined using the Company’s closing stock price on the date of issuance. The vesting terms of restricted stock issuances are generally within one year.

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Consolidated Statements of Operations (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Revenues	$ 4,488,932	$ 4,359,406	$ 8,544,507	$ 6,883,318
Cost of revenues	3,677,355	4,235,024	7,503,370	6,627,113
Research and development	5,796,022	3,972,127	10,554,535	7,133,453
Selling, general, and administrative	7,446,017	4,322,434	16,416,032	10,124,306
Total operating costs and expenses	16,919,394	12,529,585	34,473,937	23,884,872
Operating loss	(12,430,462)	(8,170,179)	(25,929,430)	(17,001,554)
Other income (expense):
Other income (expense), net	(185,737)	57,950	(375,288)	68,556
Interest expense	(105,906)	(65,844)	(200,062)	(109,405)
Nonoperating Income (Expense), Total	(291,643)	(7,894)	(575,350)	(40,849)
Loss before provision for income taxes and noncontrolling interests	(12,722,105)	(8,178,073)	(26,504,780)	(17,042,403)
Provision for income taxes	47,387	447,568	94,796	447,568
Net loss	(12,769,492)	(8,625,641)	(26,599,576)	(17,489,971)
Less - loss attributable to noncontrolling interests	(164,474)	(50,282)	(312,502)	(114,036)
Net loss attributable to NeoStem, Inc. common stockholders	$ (12,605,018)	$ (8,575,359)	$ (26,287,074)	$ (17,375,935)
Basic and diluted loss per share attributable to NeoStem, Inc. common stockholders	$ (0.40)	$ (0.46)	$ (0.88)	$ (0.99)
Weighted average common shares outstanding	31,739,417	18,503,236	29,940,128	17,606,051

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Inventories

6 Months Ended

Jun. 30, 2014

Inventories [Abstract]

Inventory Disclosure [Text Block]

Inventories

Inventories, primarily representing work in process for costs incurred on projects at PCT that have not been completed, were $2.0 million and $1.3 million as of June 30, 2014 and December 31, 2013, respectively. The Company also has deferred revenue of approximately $2.4 million and $1.5 million of advance billings received as of June 30, 2014 and December 31, 2013, respectively, related to these contracts.

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Available-for-Sale-Securities (Notes)

6 Months Ended

Jun. 30, 2014

Available-for-sale Securities [Abstract]

Cash, Cash Equivalents, and Marketable Securities [Text Block]

Available-for-Sale-Securities

The following table is a summary of available-for-sale securities recorded in cash and cash equivalents or marketable securities in our Consolidated Balance Sheets (in thousands):

	June 30, 2014
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Estimated Fair Value
Certificate of deposits	$	744.0	$	—	$	—		$	744.0
Money market funds	21,051.0		—		—			21,051.0
Municipal debt securities	6,581.3		1.1		(0.1		)	6,582.3
Total	$	28,376.3	$	1.1	$	(0.1	)	$	28,377.3

Estimated fair values of available-for-sale securities are generally based on prices obtained from commercial pricing services. The following table summarizes the classification of the available-for-sale debt securities on our Consolidated Balance Sheets (in thousands):

	June 30, 2014
Cash and cash equivalents	$	27,456.5
Marketable securities	920.8
Total	$	28,377.3

The following table summarizes our portfolio of available-for-sale debt securities by contractual maturity (in thousands):

	June 30, 2014
	Amortized Cost		Estimated Fair Value
Less than one year	$	28,376.3	$	28,377.3
Greater than one year	—		—
Total	$	28,376.3	$	28,377.3

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Summary of Significant Accounting Policies (Policies)

6 Months Ended

Jun. 30, 2014

Summary of Significant Accounting Policies [Abstract]

Schedule of Cash and Cash Equivalents [Table Text Block]

Cash and Cash Equivalents

Cash and cash equivalents include short-term, highly liquid, investments with maturities of ninety days or less when purchased.

Marketable Securities, Policy [Policy Text Block]

Marketable Securities

The Company determines the appropriate classification of our marketable securities at the time of purchase and reevaluate such designation at each balance sheet date. All of our marketable securities are considered as available-for-sale and carried at estimated fair values and reported in either cash equivalents or marketable securities. Unrealized gains and losses on available-for-sale securities are excluded from net income and reported in accumulated other comprehensive income (loss) as a separate component of stockholders' equity. Other income (expense), net, includes interest, dividends, amortization of purchase premiums and discounts, realized gains and losses on sales of securities and other-than-temporary declines in the fair value of securities, if any. The cost of securities sold is based on the specific identification method. We regularly review all of our investments for other-than-temporary declines in fair value. Our review includes the consideration of the cause of the impairment, including the creditworthiness of the security issuers, the number of securities in an unrealized loss position, the severity and duration of the unrealized losses, whether we have the intent to sell the securities and whether it is more likely than not that we will be required to sell the securities before the recovery of their amortized cost basis. When we determine that the decline in fair value of an investment is below our accounting basis and this decline is other-than-temporary, we reduce the carrying value of the security we hold and record a loss for the amount of such decline.

Receivables, Policy [Policy Text Block]

Accounts Receivable

Accounts receivable are carried at original invoice amount less an estimate made for doubtful accounts. The Company applies judgment in connection with establishing the allowance for doubtful accounts. Specifically, the Company analyzes the aging of accounts receivable balances, historical bad debts, customer concentration and credit-worthiness, current economic trends and changes in the Company’s customer payment terms. Significant changes in customer concentrations or payment terms, deterioration of customer credit-worthiness or weakening economic trends could have a significant impact on the collectability of the receivables and the Company’s operating results. If the financial condition of the Company’s customers were to deteriorate, resulting in an impairment of their ability to make payments, additional allowances may be required. Management regularly reviews the aging of receivables and changes in payment trends by its customers, and records a reserve when it believes collection of amounts due are at risk.

Inventory Disclosure [Text Block]

Inventories

The Company, through its PCT subsidiary, regularly enters into contracts with clients for services that have multiple stages and are dependent on one another to complete the contract and recognize revenue. The Company's inventory primarily represents work in process for costs incurred on such projects at PCT that have not been completed. The Company reviews these projects periodically to determine that the value of each project is stated at the lower of cost or market.

Goodwill and Intangible Assets, Policy [Policy Text Block]

Goodwill and Other Intangible Assets

Goodwill is the excess of purchase price over the fair value of identified net assets of businesses acquired. The Company’s intangible assets with an indefinite life are related to in process research and development ("IPR&D") programs acquired in the Amorcyte and CSC acquisitions, as the Company expects future research and development on these programs to provide the Company with substantial benefit for a period that extends beyond the foreseeable horizon. Intangible assets with indefinite useful lives are measured at their respective fair values as of the acquisition date. The Company does not amortize goodwill and intangible assets with indefinite useful lives. Intangible assets related to IPR&D projects are considered to be indefinite-lived until the completion or abandonment of the associated R&D efforts. If and when development is complete, which generally occurs if and when regulatory approval to market a product is obtained, the associated assets would be deemed finite-lived and would then be amortized based on their respective estimated useful lives at that point in time.

The Company reviews goodwill and indefinite-lived intangible assets at least annually for possible impairment. Goodwill and indefinite-lived intangible assets are reviewed for possible impairment between annual tests if an event occurs or circumstances change that would more likely than not reduce the fair value of the reporting unit below its carrying value. The Company tests its goodwill and indefinite-lived intangible assets each year on December 31. The Company reviews the carrying value of goodwill and indefinite-lived intangible assets utilizing a discounted cash flow model, and, where appropriate, a market value approach is also utilized to supplement the discounted cash flow model. The Company makes assumptions regarding estimated future cash flows, discount rates, long-term growth rates and market values to determine each reporting unit’s estimated fair value.

Amortized intangible assets consist of customer lists, manufacturing technology, tradenames, patents and rights. These intangible assets are amortized on a straight line basis over their respective useful lives.

Revenue Recognition, Policy [Policy Text Block]

Revenue Recognition

Clinical Services: The Company recognizes revenue for its (i) process development and (ii) clinical manufacturing services based on the terms of individual contracts.

Revenues associated with process development services generally contain multiple stages that do not have stand-alone values and are dependent upon one another, and are recognized as revenue on a completed contract basis. We recognize revenues when all of the following conditions are met:

• persuasive evidence of an arrangement exists;

• delivery has occurred or the services have been rendered;

• the fee is fixed or determinable; and

• collectability is probable.

The Company considers signed contracts as evidence of an arrangement. The Company assesses whether the fee is fixed or determinable based on the payment terms associated with the transaction and whether the payment terms are subject to refund or adjustment. The Company assesses cash collectability based on a number of factors, including past collection history with the client and the client's creditworthiness. If the Company determines that collectability is not reasonably assured, it defers revenue recognition until collectability becomes reasonably assured, which is generally upon receipt of the cash. The Company's arrangements are generally non-cancellable, though clients typically have the right to terminate their agreement for cause if the Company materially fails to perform.

Clinical manufacturing services are generally distinct arrangements whereby the Company is paid for time and materials or for fixed monthly amounts. Revenue is recognized when efforts are expended or contractual terms have been met.

Some client agreements include multiple elements, comprised of process development and clinical manufacturing services. The Company believes that process development and clinical manufacturing services each have stand-alone value because these services can be provided separately by other companies. In accordance with ASC Update No. 2009-13, “Revenue Recognition (Topic 605): Multiple-Deliverable Revenue Arrangements,” the Company (1) separates deliverables into separate units of accounting when deliverables are sold in a bundled arrangement and (2) allocates the arrangement's consideration to each unit in the arrangement based on its relative selling price. 

Clinical Services Reimbursements: The Company separately charges the customers for the expenses associated with certain consumable resources (reimbursable expenses) that are specified in each clinical services contract. On a monthly basis, the Company bills customers for reimbursable expenses and immediately recognizes these billings as revenue, as the revenue is deemed earned as reimbursable expenses are incurred. For the three months endedJune 30, 2014 and 2013, clinical services reimbursements were $1.1 million and $0.4 million, respectively. For the six months endedJune 30, 2014 and 2013, clinical services reimbursements were $1.8 million and $0.8 million, respectively.

Processing and Storage Services: The Company recognizes revenue related to the collection and cryopreservation of cord blood and autologous adult stem cells when the cryopreservation process is completed which is approximately twenty-four hours after cells have been collected. Revenue related to advance payments of storage fees is recognized ratably over the period covered by the advance payments.

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Share-Based Compensation (Notes)

6 Months Ended

Jun. 30, 2014

Share-based Compensation [Abstract]

Disclosure of Compensation Related Costs, Share-based Payments [Text Block]

Share-Based Compensation

Share-based Compensation

We utilize share-based compensation in the form of stock options, warrants and restricted stock.  The following table summarizes the components of share-based compensation expense for the three and six months endedJune 30, 2014 and 2013 (in thousands):

	Three Months Ended June 30,				Six Months Ended June 30,
	2014		2013		2014		2013
Cost of goods sold	$	98.5	$	58.5	$	236.6	$	145.0
Research and development	371.6		129.8		848.4		347.1
Selling, general and administrative	1,289.6		907.4		4,568.5		2,822.1
Total share-based compensation expense	$	1,759.7	$	1,095.7	$	5,653.5	$	3,314.2

Total compensation cost related to nonvested awards not yet recognized and the weighted-average periods over which the awards are expected to be recognized at June 30, 2014 were as follows (dollars in thousands):

	Stock Options		Warrants		Restricted Stock
Unrecognized compensation cost	$	6,814.9	$	33.4	$	262.9
Expected weighted-average period in years of compensation cost to be recognized	5.02		1.05		0.19

Total fair value of shares vested and the weighted average estimated fair values of shares granted for the six months endedJune 30, 2014 and 2013 were as follows (dollars in thousands):

	Stock Options				Warrants
	Six Months Ended June 30,				Six Months Ended June 30,
	2014		2013		2014		2013
Total fair value of shares vested	$	2,552.2	$	1,646.3	$	15.0	$	80.9
Weighted average estimated fair value of shares granted	$	4.92	$	4.58	$	—	$	3.51

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Goodwill and Other Intangible Assets

6 Months Ended

Jun. 30, 2014

Goodwill and Other Intangible Assets [Abstract]

Goodwill and Intangible Assets [Text Block]

Goodwill and Other Intangible Assets

The following table summarizes the changes in the carrying amount of goodwill (in thousands):

	Total
Balance as of December 31, 2013	$	11,117.7
Goodwill resulting from the acquisition of CSC	14,961.8
Balance as of June 30, 2014	$	26,079.5

The Company's intangible assets and related accumulated amortization as of June 30, 2014 and December 31, 2013 consisted of the following (in thousands):

		June 30, 2014							December 31, 2013
	Useful Life	Gross		Accumulated Amortization			Net		Gross		Accumulated Amortization			Net
Customer list	10 years	$	1,000.0	$	(345.1	)	$	654.9	$	1,000.0	$	(295.1	)	$	704.9
Manufacturing technology	10 years	3,900.0		(1,345.9		)	2,554.1		3,900.0		(1,150.9		)	2,749.1
Tradename	10 years	800.0		(276.1		)	523.9		800.0		(236.1		)	563.9
In process R&D	Indefinite	45,190.0		—			45,190.0		9,400.0		—			9,400.0
Patent rights	19 years	669.0		(228.9		)	440.1		669.0		(211.3		)	457.7
Total Intangible Assets		$	51,559.0	$	(2,196.0	)	$	49,363.0	$	15,769.0	$	(1,893.4	)	$	13,875.6

Total intangible amortization expense was classified in the operating expense categories for the periods included below as follows (in thousands):

	Six Months Ended June 30,
	2014		2013
Cost of revenue	$	158.4	$	195.0
Research and development	54.2		17.6
Selling, general and administrative	90.0		90.0
Total	$	302.6	$	302.6

Estimated intangible amortization expense on an annual basis for the succeeding five years is as follow (in thousands):

2014	$	302.6
2015	605.2
2016	605.2
2017	605.2
2018	605.2
Thereafter	46,639.6
	$	49,363.0

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Loss Per Share

6 Months Ended

Jun. 30, 2014

Loss Per Share [Abstract]

Loss Per Share [Text Block]

Loss Per Share

For the six months endedJune 30, 2014 and 2013, the Company incurred net losses and therefore no common stock equivalents were utilized in the calculation of loss per share. At June 30, 2014 and 2013, the Company excluded the following potentially dilutive securities:

	June 30,
	2014	2013
Stock Options	4,204,270	2,647,437
Warrants	3,623,956	5,430,137
Restricted Shares	205,231	73,500

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Fair Value Measurements

6 Months Ended

Jun. 30, 2014

Fair Value Measurements [Abstract]

Fair Value Disclosures [Text Block]

Fair Value Measurements

Fair value of financial assets and liabilities that are being measured and reported are defined as the exchange price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants in the principal market at the measurement date (exit price). The Company is required to classify fair value measurements in one of the following categories:

Level 1 inputs are defined as quoted prices (unadjusted) in active markets for identical assets or liabilities that the reporting entity has the ability to access at the measurement date.

Level 2 inputs are defined as inputs other than quoted prices included within Level 1 that are observable for the assets or liabilities, either directly or indirectly.

Level 3 inputs are defined as unobservable inputs for the assets or liabilities. Financial assets and liabilities are classified based on the lowest level of input that is significant to the fair value measurement. The Company’s assessment of the significance of a particular input to the fair value measurement requires judgment, and may affect the valuation of the fair value of assets and liabilities and their placement within the fair value hierarchy levels.

The Company classifies the fair value of the warrant derivative liabilities as level 3 inputs. These inputs require material subjectivity because value is derived through the use of a lattice model that values the derivatives based on probability weighted discounted cash flows. In May 2014, the warrants expired and the value of the warrant derivative liabilities were written off and recorded in other expenses in our consolidated statement of operations.

The Company classifies the fair value of contingent consideration obligations as level 3 inputs. The Company has recognized contingent consideration obligations related to the following:

• In October 2011, in connection with the Company's acquisition of Amorcyte, contingent consideration obligations were recognized relating to earn out payments equal to 10% of the net sales of the lead product candidate NBS10 (in the event of and following the date of first commercial sale of NBS10), provided that in the event NeoStem sublicenses NBS10, the applicable earn out payment will be equal to 30% of any sublicensing fees, and provided further that NeoStem will be entitled to recover direct out-of-pocket clinical development costs not previously paid or reimbursed and any costs, expenses, liabilities and settlement amounts arising out of claims of patent infringement or otherwise challenging Amorcyte’s right to use intellectual property, by reducing any earn out payments due by 50% until such costs have been recouped in full (the “Earn Out Payments”). The contingent consideration fair value increased from $9.5 million as of December 31, 2013 to $9.9 million as of June 30, 2014. The change in estimated fair value is based or the impact of the time progression through the Phase 2 clinical trial from December 31, 2013 to June 30, 2014, and has been recorded in other expenses in our consolidated statement of operations.

• In May 2014, in connection with the Company's acquisition of CSC, contingent consideration obligations were recognized relating to milestone payments of up to $90.0 million, based on the achievement of certain milestones associated with the future development of the acquired programs. The contingent consideration fair value recognized in the acquisition in May 2014 was $10.8 million. There was no change in estimated fair value as of June 30, 2014.

The fair value of contingent consideration obligations is based on discounted cash flow models using a probability-weighted income approach. The measurements are based upon unobservable inputs supported by little or no market activity based on our own assumptions and experience. The Company bases the timing to complete the development and approval programs on the current development stage of the product and the inherent difficulties and uncertainties in developing a product candidate, such as obtaining U.S. Food and Drug Administration (FDA) and other regulatory approvals. In determining the probability of regulatory approval and commercial success, we utilize data regarding similar milestone events from several sources, including industry studies and our own experience. These fair value measurements represent Level 3 measurements as they are based on significant inputs not observable in the market. Significant judgment is employed in determining the appropriateness of these assumptions as of the acquisition date and for each subsequent period. Accordingly, changes in assumptions could have a material impact on the amount of contingent consideration expense we record in any given period.

The following table sets forth by level within the fair value hierarchy the Company’s financial assets and liabilities that were accounted for at fair value on a recurring basis as of June 30, 2014, and December 31, 2013 (in thousands):

	June 30, 2014								December 31, 2013
	Level 1		Level 2		Level 3		Total		Level 1		Level 2		Level 3		Total
Assets:
Marketable securities - available for sale	$	—	$	920.8	$	—	$	920.8	$	—	$	—	$	—	$	—
	$	—	$	920.8	$	—	$	920.8	$	—	$	—	$	—	$	—
Liabilities:
Warrant derivative liabilities	$	—	$	—	$	—	$	—	$	—	$	—	$	23.2	$	23.2
Contingent consideration	—		—		20,640.0		20,640.0		—		—		9,450.0		9,450.0
	$	—	$	—	$	20,640.0	$	20,640.0	$	—	$	—	$	9,473.2	$	9,473.2

For those financial instruments with significant Level 3 inputs, the following table summarizes the activity for the six months endedJune 30, 2014 by type of instrument (in thousands):

	Six Months Ended
	June 30, 2014
	Warrants			Contingent Consideration		Total
Beginning liability balance	$	23.2		$	9,450.0	$	9,473.2
Amount issued in acquisition	—			10,790.0		10,790.0
Change in fair value recorded in earnings	—			400.0		400.0
Expiration	(23.2		)	—		(23.2		)
Ending liability balance	$	—		$	20,640.0	$	20,640.0

Some of the Company’s financial instruments are not measured at fair value on a recurring basis, but are recorded at amounts that approximate fair value due to their liquid or short-term nature, such as cash and cash equivalents, accounts receivable, accounts payable. Our long-term debt and notes payable are carried at cost and approximate fair value due to their variable or fixed interest rates, which are consistent with the interest rates in the market.

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Accrued Liabilities

6 Months Ended

Jun. 30, 2014

Accrued Liabilities [Abstract]

Accounts Payable and Accrued Liabilities Disclosure [Text Block]

Accrued Liabilities

Accrued liabilities as of June 30, 2014 and December 31, 2013 were as follows (in thousands):

	June 30, 2014		December 31, 2013
Salaries, employee benefits and related taxes	$	1,443.2	$	2,325.8
Professional fees	651.7		544.8
License fees	100.0		500.0
Other	392.4		647.4
	$	2,587.3	$	4,018.0

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The Business (Details) (USD $)	0 Months Ended		6 Months Ended
	Jun. 18, 2012 segment	Jun. 19, 2012 segment	Jun. 30, 2014
The Company [Line Items]
Change in Ownership in Subsidiary			$ 0
Number of Reporting Segments	3	1
Noncontrolling Interest [Member]
The Company [Line Items]
Change in Ownership in Subsidiary			$ 86,618

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Shareholders' Equity Equity Issuances (Details) (USD $)	6 Months Ended							6 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	May 08, 2014	Dec. 31, 2013	Jun. 30, 2014 Aspire Capital Purchase Agreement [Member]	Mar. 31, 2014 Aspire Capital Purchase Agreement [Member]	Sep. 28, 2011 Aspire Capital Purchase Agreement [Member]	Jun. 30, 2014 Aegis Capital Purchase Agreement [Member]	Jun. 30, 2014 Aspire Capital Purchase Agreement [Member]	Jun. 30, 2014 Maximum [Member]
Class of Stock [Line Items]
Committment Value Under Purchase Agreement						$ 20,000,000
Term Of Agreement In Months					24		24
Discount Applied To Weighted Average Price					5.00%
Shares, Issued								800,000
Proceeds from Issuance of Common Stock Gross								5,600,000
Common Stock, Shares, Issued	34,939,223		5,329,593	27,196,537					150,000
Purchase Commitment, Remaining Minimum Amount Committed									30,000,000
Stock Issued During Period, Shares, New Issues								700,000
Net proceeds from issuance of common stock	10,149,438	14,248,148						4,400,000
Stock Option Exercise	41,136
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Upper Range Limit										$ 6.20
Proceeds from Stock Options Exercised	$ 200,000

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Related Party Transactions

6 Months Ended

Jun. 30, 2014

Related Party Transactions [Abstract]

Related Party Transactions [Text Block]

Related Party Transactions

In December 2013, the Company modified both the First Mortgage and Second Mortgage with TD Bank, N.A. (see Note 10). Pursuant to the Loan Modifications, Andrew L. Pecora, M.D., Regional Cancer Care Associates LLC (Dr. Pecora’s medical practice), and certain partners in such practice, including Dr. Pecora, have been released as guarantors of the Second Mortgage Loan, and NeoStem has become a guarantor of the Loans pursuant to a Guaranty of Payment delivered by NeoStem to the Lender. Dr. Pecora, currently serves as a NeoStem director, NeoStem’s Chief Visionary Officer, PCT’s Chief Medical Officer and Amorcyte’s Chief Scientific Officer.

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Available-for-Sale-Securities (Tables)

6 Months Ended

Jun. 30, 2014

Available-for-sale Securities [Abstract]

Schedule of Available-for-sale Securities Reconciliation [Table Text Block]

The following table is a summary of available-for-sale securities recorded in cash and cash equivalents or marketable securities in our Consolidated Balance Sheets (in thousands):

	June 30, 2014
	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Estimated Fair Value
Certificate of deposits	$	744.0	$	—	$	—		$	744.0
Money market funds	21,051.0		—		—			21,051.0
Municipal debt securities	6,581.3		1.1		(0.1		)	6,582.3
Total	$	28,376.3	$	1.1	$	(0.1	)	$	28,377.3

Marketable Securities [Table Text Block]

Estimated fair values of available-for-sale securities are generally based on prices obtained from commercial pricing services. The following table summarizes the classification of the available-for-sale debt securities on our Consolidated Balance Sheets (in thousands):

	June 30, 2014
Cash and cash equivalents	$	27,456.5
Marketable securities	920.8
Total	$	28,377.3

Investments Classified by Contractual Maturity Date [Table Text Block]

The following table summarizes our portfolio of available-for-sale debt securities by contractual maturity (in thousands):

	June 30, 2014
	Amortized Cost		Estimated Fair Value
Less than one year	$	28,376.3	$	28,377.3
Greater than one year	—		—
Total	$	28,376.3	$	28,377.3

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Debt (Details) (USD $)			0 Months Ended	6 Months Ended		6 Months Ended	0 Months Ended
	Jun. 30, 2014	Dec. 31, 2013	Oct. 31, 2007 Convertible Notes Payable [Member]	Jun. 30, 2014 Convertible Notes Payable [Member]	Dec. 31, 2013 Convertible Notes Payable [Member]	Jun. 30, 2014 PCT Allendale, LLC [Member]	Dec. 06, 2010 PCT Allendale, LLC [Member] Convertible Notes Payable [Member]	Jun. 30, 2014 PCT Allendale, LLC [Member] Convertible Notes Payable [Member]	Dec. 31, 2013 PCT Allendale, LLC [Member] Convertible Notes Payable [Member]
Debt Instrument [Line Items]
Notes Payable	$ 1,800,000	$ 900,000
Purchase of condominium units			0
Debt Instrument, Frequency of Periodic Payment			monthly payments
Debt Instrument, Periodic Payment						20,766
Debt Instrument, Periodic Payment, Interest				5.00%			6.00%
Mortgage Loans on Real Estate, Carrying Amount of Mortgages				2,400,000	2,500,000			720,300	763,000
Mortgage Loan Repayble Amount within 12 months						130,000		89,000
Mortgage Loans on Real Estate, New Mortgage Loans			$ 3.1				$ 1,000,000
Debt Instrument, Period of Loan							124 months
Debt Instrument, Period of Fixed Interest Rate							64 months

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Inventories (Details) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Schedule of Inventory [Line Items]
Inventory	$ 2,033,011	$ 1,270,223
Multiple Stage Contracts [Member]
Schedule of Inventory [Line Items]
Deferred Revenue	$ 2,400,000	$ 1,500,000

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Consolidated Statements of Comprehensive Loss (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Net loss	$ (12,769,492)	$ (8,625,641)	$ (26,599,576)	$ (17,489,971)
Available for sale securities - net unrealized gain	998	0	998	0
Total other comprehensive income	998	0	998	0
Comprehensive loss	(12,768,494)	(8,625,641)	(26,598,578)	(17,489,971)
Comprehensive loss attributable to noncontrolling interests	(164,474)	(50,282)	(312,502)	(114,036)
Comprehensive net loss attributable to NeoStem, Inc. common stockholders	$ (12,604,020)	$ (8,575,359)	$ (26,286,076)	$ (17,375,935)

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Acquisition (Notes)

6 Months Ended

Jun. 30, 2014

Business Combinations [Abstract]

Mergers, Acquisitions and Dispositions Disclosures [Text Block]

Acquisition

On May 8, 2014 (the “Closing”), NeoStem closed its acquisition of CSC (the “CSC Acquisition”), pursuant to the terms of the Agreement and Plan of Merger, dated as of April 11, 2014 (the “Merger Agreement”), by and among NeoStem, CSC, NBS Acquisition Sub I, Inc., a Delaware corporation and a wholly-owned subsidiary of NeoStem (“Subco”), NBS Acquisition Sub II, LLC, a Delaware limited liability company and a wholly-owned subsidiary of NeoStem (“Subco II”), and Jason Livingston, solely in his capacity as CSC stockholder representative (together with his permitted successors, the “CSC Representative”). At Closing, Fortis Advisors LLC succeeded to the duties of the CSC Representative pursuant to the Merger Agreement.

Pursuant to the Merger Agreement, on the Closing Date, (1) Subco was merged with and into CSC (the “First Merger”) and (2) CSC was then merged with and into Subco II (the “Second Merger”, and collectively with the First Merger, the “Mergers”), with Subco II surviving the Mergers as a wholly-owned subsidiary of NeoStem. At Closing, Subco II changed its legal name to NeoStem Oncology, LLC.

CSC is a biopharmaceutical company with deep expertise in stem cell biology that is engaged in the development of therapies using a patient’s own, i.e., autologous, cells. Its development efforts are primarily directed at immunotherapies for cancer. Its most advanced program is an immunotherapy, NBS20, also referred to as DC/TC (dendritic cell/tumor cell), which uses patients’ own tumor cells to maximize the ability of their immune system to identify and eliminate the cancer initiating cells that are capable of reconstituting or developing new tumors (i.e., “cancer stem cells” or “replicating cells”). The current focus of that program is the treatment of metastatic melanoma. As a result of encouraging Phase 2 data, the Company expects to initiate a Phase 3 clinical trial later in 2014, for which it has received Special Protocol Assessment (“SPA”) and Fast Track designation, as well as Orphan Drug designation.

Aggregate Merger Consideration

Pursuant to the terms of the Merger Agreement, all shares of CSC common stock (“CSC Common Stock”) and CSC preferred stock (“CSC Preferred Stock”, and collectively with the CSC Common Stock, the “CSC Capital Stock”) outstanding immediately prior to the Closing, and all outstanding unexercised options to purchase CSC Common Stock (“CSC Options”) (treated as if a net exercise had occurred), were canceled and converted into the right to receive, in the aggregate (and giving effect to the liquidation preferences accorded to the CSC Preferred Stock):

(1)An aggregate of 5,329,593 shares of NeoStem common stock (subject to payment of nominal cash in lieu of fractional shares) (the “Closing Merger Consideration”).

(2)if payable after the Closing, certain payments in an amount of up to $90.0 million in the aggregate, payable in shares of NeoStem Common Stock or cash, in NeoStem’s sole discretion, in the event of the successful completion of certain milestone events in connection with the CSC business being acquired by NeoStem (the “Milestone Payments”, and together with the Closing Merger Consideration, the “Merger Consideration”).

The fair value of the net assets acquired in the CSC Acquisition was $20.3 million. The fair value of the consideration paid by NeoStem was valued at $35.3 million, resulting in the recognition of goodwill in the amount of $15.0 million. The consideration paid was comprised of equity issued and milestone payments. The fair value of the equity issued by NeoStem was valued at $24.5 million. The fair value of the milestone payments was valued at $10.8 million, and is contingent on the achievement of certain milestones associated with the future development of the acquired programs. Such contingent consideration has been classified as a liability and will be subject to remeasurement.

The preliminary fair value of assets acquired and liabilities assumed on May 8, 2014 is as follows (in thousands):

Cash and cash equivalents	$	51.2
Accounts receivable trade, net	45.1
Prepaids and other current assets	19.2
Property, plant and equipment, net	1,040.9
Other assets	201.0
Goodwill	14,961.9
In-Process R&D	35,790.0
Accounts payable	(333.1		)
Accrued liabilities	(2,014.1		)
Deferred tax liability	(14,509.3		)
	$	35,252.8

The total cost of the acquisition, which is still preliminary, has been allocated to the assets acquired and the liabilities assumed based upon their estimated fair values at the date of the acquisition. The final allocation is pending the receipt of a third-party valuation and the completion of the Company’s internal review, which is expected during fiscal 2014.

For the period since the acquisition (May 9, 2014 to June 30, 2014), NeoStem recorded $0.01 million in revenues and a net loss of approximately $2.3 million or $0.07 basic and diluted loss per share attributable to CSC.

Pro Forma Financial Information

The following supplemental table presents unaudited consolidated pro forma financial information as if the closing of the acquisition of CSC had occurred on January 1, 2013 (in thousands, except per share amounts):

	Three Months Ended June 30, 2014						Six Months Ended June 30, 2014
	(As Reported)			(Proforma)			(As Reported)			(Proforma)
Revenues	$	4,489		$	4,982		$	8,545		$	9,255
Net loss	$	(12,770	)	$	(13,574	)	$	(26,600	)	$	(29,097	)
Net loss attributable to NBS	$	(12,605	)	$	(13,409	)	$	(26,287	)	$	(28,784	)
Net loss per share attributable to NBS	$	(0.40	)	$	(0.36	)	$	(0.88	)	$	(0.82	)

	Three Months Ended June 30, 2013						Six Months Ended June 30, 2013
	(As Reported)			(Proforma)			(As Reported)			(Proforma)
Revenues	$	4,359		$	4,596		$	6,883		$	7,282
Net loss	$	(8,626	)	$	(9,830	)	$	(17,490	)	$	(19,963	)
Net loss attributable to NBS	$	(8,575	)	$	(9,780	)	$	(17,376	)	$	(19,849	)
Net loss per share attributable to NBS	$	(0.46	)	$	(0.41	)	$	(0.99	)	$	(0.87	)

The unaudited supplemental pro forma financial information should not be considered indicative of the results that would have occurred if the acquisition of CSC had been consummated on January 1, 2013, nor are they indicative of future results.

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Loss Per Share (Tables)

6 Months Ended

Jun. 30, 2014

Loss Per Share [Abstract]

ScheduleOfDilutiveSecuritiesExcludedFromComputationOfEarningsPerShare [Table Text Block]

At June 30, 2014 and 2013, the Company excluded the following potentially dilutive securities:

	June 30,
	2014	2013
Stock Options	4,204,270	2,647,437
Warrants	3,623,956	5,430,137
Restricted Shares	205,231	73,500

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Available-for-Sale-Securities Schedule of Available-for-sale Securites Reconciliation (Details) (USD $)	Jun. 30, 2014
Schedule of Available-for-sale Securities [Line Items]
Available-for-sale Securities, Amortized Cost Basis	$ 28,376,300
Deferred Tax Liabilities, Unrealized Gains on Trading Securities	1,100
Available-for-sale Securities, Continuous Unrealized Loss Position, Fair Value	(100)
Certificates of Deposit, at Carrying Value	28,377,300
Municipal Bonds [Member]
Schedule of Available-for-sale Securities [Line Items]
Available-for-sale Securities, Amortized Cost Basis	6,581,300
Deferred Tax Liabilities, Unrealized Gains on Trading Securities	1,100
Available-for-sale Securities, Continuous Unrealized Loss Position, Fair Value	100
Certificates of Deposit, at Carrying Value	6,582,300
Money Market Funds [Member]
Schedule of Available-for-sale Securities [Line Items]
Available-for-sale Securities, Amortized Cost Basis	21,051,000
Deferred Tax Liabilities, Unrealized Gains on Trading Securities	0
Deferred Tax Assets, Unrealized Losses on Trading Securities	0
Certificates of Deposit, at Carrying Value	21,051,000
Certificates of Deposit [Member]
Schedule of Available-for-sale Securities [Line Items]
Available-for-sale Securities, Amortized Cost Basis	744,000
Deferred Tax Liabilities, Unrealized Gains on Trading Securities	0
Deferred Tax Assets, Unrealized Losses on Trading Securities	0
Certificates of Deposit, at Carrying Value	$ 744,000

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Income Taxes

6 Months Ended

Jun. 30, 2014

Income Taxes [Abstract]

Income Tax Disclosure [Text Block]

Income Taxes

As of December 31, 2013, the Company had approximately $110.6 million of Federal NOLs available to offset future taxable income expiring from 2025 through 2033. In accordance with Section 382 of the Internal Revenue code, the usage of the Company’s NOLs could be limited in the event of a change in ownership. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the period when those temporary differences become deductible.  If a change of ownership did occur there would be an annual limitation on the usage of the Company’s losses which are available through 2033.

In assessing the realizability of deferred tax assets, including the net operating loss carryforwards ("NOLs"), the Company assesses the available positive and negative evidence to estimate if sufficient future taxable income will be generated to utilize its existing deferred tax assets.  Based on its assessment, the Company has provided a full valuation allowance against its net deferred tax assets as their future utilization remains uncertain at this time.

Deferred tax liabilities were $19.0 million and $4.4 million as of June 30, 2014 and December 31, 2013, and relate to the taxable temporary differences on (i) the goodwill recognized in the PCT acquisition in 2011, (ii) the in-process R&D intangible asset recognized in the Amorcyte acquisition in 2011, and (iii) the in-process R&D intangible asset recognized in the CSC acquisition in 2014. The taxable temporary difference associated with the goodwill, which is tax deductible and will be amortized over 15 years, will continue to increase the deferred tax liability balance over the amortization period, with an associated charge to the tax provision in each period. The deferred tax liabilities will only reverse when these indefinite-lived assets are sold, impaired, or reclassified from an indefinite-lived asset to a finite-lived asset.

As of June 30, 2014, management does not believe the Company has any material uncertain tax positions that would require it to measure and reflect the potential lack of sustainability of a position on audit in its financial statements. The Company will continue to evaluate its uncertain tax positions in future periods to determine if measurement and recognition in its financial statements is necessary. The Company does not believe there will be any material changes in its unrecognized tax positions over the next year.