8-K

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 8-K

CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): July 7, 2004

GENENTECH, INC.
(Exact name of Registrant as specified in its charter)

Delaware
(State or other jurisdiction
of incorporation) 1-9813
(Commission
File Number) 94-2347624
(I.R.S. Employer
Identification No.)

1 DNA Way
South San Francisco, California 94080-4990
(Address of principal executive offices and Zip Code)

Registrant's telephone number, including area code: (650) 225-1000

ITEM 5. OTHER EVENTS

On July 7, 2004, Genentech, Inc., a Delaware corporation, issued a press release announcing earnings for the quarter ended June 30, 2004. A copy of the earnings press release is filed as Exhibit 99.1 to this report.

The non-GAAP financial measures used within our earnings press release include net income and earnings per share (or EPS) for the three and six months ended June 30, 2004 and 2003. These non-GAAP financial measures exclude recurring charges related to the redemption of our callable putable common stock on June 30, 1999 (the "Redemption") and the effects of push-down accounting, litigation-related special charges, and their related tax effects.

Each non-GAAP financial measure presented in the earnings press release is included because our management uses this information to monitor and evaluate Genentech's operating results and trends on an on-going basis. Our management believes the non-GAAP information is also useful for investors because the amounts relating to the Redemption and push-down accounting and the litigation-related special items that are excluded were the result of transactions that are unusual due to their nature, size or infrequency. Consequently, excluding those items from our operating results provides users of the financial statements an important insight into our operating results and related trends that affect our business. In addition, our management uses non-GAAP financial information and measures internally for operating, budgeting and financial planning purposes.

ITEM 7. FINANCIAL STATEMENTS AND EXHIBITS

      (c)  Exhibits.

                99.1  Earnings Press Release of Genentech, Inc. dated July 7, 2004.

Page 2

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

		GENENTECH, INC.
Date:	July 7, 2004	/s/ARTHUR D. LEVINSON
		Arthur D. Levinson, Ph.D. Chairman and Chief Executive Officer
Date:	July 7, 2004	/s/LOUIS J. LAVIGNE, JR.
		Louis J. Lavigne, Jr. Executive Vice President and Chief Financial Officer
Date:	July 7, 2004	/s/JOHN M. WHITING
		John M. Whiting Vice President, Controller and Chief Accounting Officer

Page 3

EXHIBIT INDEX

Exhibit No.	Description
99.1	Earnings Press Release of Genentech, Inc. dated July 7, 2004.

Page 4

EX-99.1

EXHIBIT 99.1

Genentech	NEWS RELEASE
	Media Contact:	Debra Charlesworth Caroline Pecquet	(650) 225-2742 (650) 467-7078
	Investor Contact:	Kathee Littrell	(650) 225-1034
	http://www.gene.com

GENENTECH ANNOUNCES SECOND QUARTER 2004 RESULTS

- Product Sales Increase 42 Percent, Drive Record Quarterly Revenues of $1.1 Billion -

SOUTH SAN FRANCISCO, Calif. -- July 7, 2004 -- Genentech, Inc. (NYSE: DNA) today announced total product sales of $913.4 million for the second quarter of 2004, a 42 percent increase over product sales of $644.3 million in the second quarter of 2003. Operating revenues increased by 41 percent from the second quarter of 2003 to $1.1 billion. Avastin™ (bevacizumab), in its first full quarter of sales, realized sales of $133.0 million for the second quarter of 2004.

            "Genentech topped $1 billion in quarterly revenues for the first time in our history, and we are exiting the first half of the year with revenues of more than $2 billion," said Arthur D. Levinson, Ph.D., Genentech's chairman and chief executive officer. "Our unrelenting focus on science has led us to launch three successful products, Avastin, Xolair and RAPTIVA, in a recent nine-month period. We remain committed to our 5x5 goals, and our recent product launches direct us toward our Horizon 2010 objectives."

            "The success of new product launches and the continued strength of our existing product sales are driving our operating revenues growth of 41 percent over the same quarter last year," said Myrtle Potter, president of Commercial Operations. "Rituxan continued to exhibit healthy growth, with a 17 percent increase over the same period last year. Also, our new product launches are contributing to ongoing revenue growth. Our three new product launches contributed $190.1 million or 21 percent of total net product sales for the second quarter of 2004. Our teams are also gearing up for the potential upcoming launch of Tarceva."

            "We continue to deliver on our earnings per share targets while making strong investments in our new product launches and research and development initiatives," said Louis J. Lavigne, Jr., Genentech's executive vice president and chief financial officer. "Based on our current view of the business, we have now raised our goal for 2004 non-GAAP EPS to be in the range of $0.75 to $0.80."

- 1 -

For the three months ended June 30, 2004:

• Operating revenues increased 41 percent to $1,128.2 million from $799.7 million in the second quarter of 2003. Total product sales increased 42 percent to $913.4 million from $644.3 million in the second quarter of 2003.
   
• Non-GAAP net income increased 23 percent to $201.8 million from $163.5 million in the second quarter of 2003. GAAP net income increased 29 percent to $170.8 million from $132.3 million in the second quarter of 2003.
   
• Non-GAAP earnings per share increased 19 percent to $0.19 per share from $0.16 per share in the second quarter of 2003. GAAP earnings per share increased by 23 percent to $0.16 per share from $0.13 per share in the second quarter of 2003.

Note:  Genentech's non-GAAP earnings per share and non-GAAP net income exclude recurring charges related to the 1999 Roche redemption of Genentech's stock, and litigation-related special items. The differences in non-GAAP and GAAP numbers are reconciled in the tables below and on www.gene.com. All share and per share amounts reflect the May 2004 two-for-one split of Genentech common stock.

Along with the discontinuation of Nutropin Depot® (somatropin [RDNA origin] for injectable suspension), Genentech took a charge of $37.4 million, of which $18.6 million was related to the Nutropin Depot license and $18.8 million was related to inventory. In addition, during the quarter, Genentech took a provision of $21.3 million related to filling failures for other products.

Product Sales

For the three months ended June 30, 2004:

• Sales of marketed products increased 42 percent to $913.4 million from $644.3 million in the second quarter of 2003.
   
• BioOncology sales were 74 percent of total product revenues compared to 73 percent of total product revenues in the second quarter of 2003.
   
• Avastin, in its first full quarter of sales, realized sales of $133.0 million for the quarter.
   
• Rituxan® (Rituximab) sales increased 17 percent to $424.7 million from $363.4 million in the second quarter of 2003.
   
• Net U.S. sales were $390 million, a 19 percent increase from the second quarter of 2003.
   
• Ex-U.S. sales were $34.7 million compared to $35.4 million in the second quarter of 2003.
   
• Herceptin® (Trastuzumab) sales increased 8 percent to $117.7 million from $109.1 million in the second quarter of 2003.
   
• Xolair® (Omalizumab) sales were $43.7 million for the quarter.

 - 2 -

• RAPTIVA® (efalizumab) sales were $13.4 million for the quarter.
   
• Sales of legacy products, including growth hormone, cardiovascular products and Pulmozyme® (dornase alfa, recombinant) Inhalation Solution, increased 5 percent to $180.9 million from $171.8 million in the second quarter of 2003.

Royalties
            Royalties grew to $151.9 million compared to $122.8 million in the second quarter of 2003. The increase is primarily due to higher royalties from Roche for Rituxan and Herceptin.

Contract Revenues
            Contract revenues increased to $62.9 million compared to $32.6 million in the second quarter of 2003. The increase is primarily due to higher revenues from ongoing collaborations, including ongoing payments after opt-ins from Roche and other parties.

Total Costs and Expenses
            Costs and expenses increased as anticipated in the second quarter of 2004 in comparison to costs and expenses in the second quarter of 2003.

• Research and development (R&D) expenses were $212.9 million compared to $180.2 million in the second quarter of 2003. R&D expenses as a percentage of operating revenues were 19 percent compared to 23 percent in the second quarter of 2003.
   
• Cost of sales increased to $186.7 million from $123.4 million in the second quarter of 2003, primarily due to the inclusion of an $18.8 million charge related to Nutropin Depot inventory and a provision of $21.3 million related to filling failures for other products. Cost of sales as a percentage of product sales was 20 percent compared to 19 percent in the second quarter of 2003.
   
• Marketing, general and administrative (MG&A) expenses increased to $276.7 million compared to $184.3 million in the second quarter of 2003 due to ongoing expenses for commercial products, primarily related to the launch of three new products and preparation for the potential launch of Tarceva&trade (erlotinib HCl), and a charge of $18.6 million related to the license for Nutropin Depot. MG&A expenses as a percentage of operating revenues increased to 25 percent compared to 23 percent in the second quarter of 2003.
   
• Collaboration profit-sharing expenses in the second quarter of 2004 increased to $145.2 million compared to $107.3 million in the second quarter of 2003. The growth in these expenses is attributable to higher Rituxan and Xolair sales.

- 3 -

Webcast:
Genentech will be offering a live webcast of a discussion by Genentech management of the earnings and other business results on Wednesday, July 7, 2004, at 2:15 p.m. Pacific Time (PT). The live webcast may be accessed on Genentech's website at http://www.gene.com. This webcast will also be available after the call via the website until 5:00 p.m. PT on July 21, 2004. An audio replay of the webcast will be available beginning at 5:15 p.m. PT on July 7, 2004 through 5:15 p.m. PT on July 14, 2004. Access numbers for this replay are: 1-800-642-1687 (U.S./Canada) and 1-706-645-9291 (international); conference ID number is 8133116.

About Genentech:
Genentech is a leading biotechnology company that discovers, develops, manufactures and commercializes biotherapeutics for significant unmet medical needs. Eighteen of the currently approved biotechnology products originated from or are based on Genentech science. Genentech manufactures and commercializes 12 biotechnology products directly in the United States. The company has headquarters in South San Francisco, California and is traded on the New York Stock Exchange under the symbol DNA. For press releases and additional information about the company, please visit http://www.gene.com.

Genentech Business and Product Development
Events in the Second Quarter 2004

MARKETED AND PIPELINE PRODUCT EVENTS

Oncology

Medical Meetings:  Data from more than 150 abstracts were presented on Genentech oncology products at the 40^th Annual Meeting of the American Society of Clinical Oncology (ASCO) on June 5-8.

Avastin:  Genentech and Roche announced that The New England Journal of Medicine published Genentech's Phase III pivotal trial for Avastin in first-line (previously untreated) metastatic colorectal cancer. The study showed that the addition of Avastin to the IFL (5-FU/Leucovorin/CPT-11) chemotherapy regimen significantly extended survival in patients with first-line metastatic colorectal cancer. The median survival of patients treated with Avastin plus the IFL chemotherapy regimen was extended by approximately five months, compared to patients treated with the IFL chemotherapy regimen alone.

Genentech enrolled the first patient in the Avastin Phase III pancreatic cancer study in early June.

Tarceva:  At ASCO, Genentech announced with OSI Pharmaceuticals, Inc. and Roche that a Phase III study of Tarceva in advanced non-small cell lung cancer (NSCLC) demonstrated a 42.5 percent improvement in median survival and a 41 percent improvement in one-year survival rates compared to placebo.

- 4 -

In late June, OSI Pharmaceuticals announced that the New Drug Application for Tarceva was accepted into the U.S. Food and Drug Administration's Pilot 1 Program for Continuous Marketing Applications. The Pilot 1 Program is designed for products that have been designated Fast Track status and have demonstrated significant promise in clinical trials as a therapeutic advance over available therapy for the disease or condition.

On June 16, 2004,Genentech and OSI Pharmaceuticals announced agreements detailing the roles of the two companies with respect to promotion, marketing and manufacturing of Tarceva, if it is approved for distribution in the United States.

After the completion of the first stage of a Phase II study of Tarceva for glioblastoma multiforme (GBM) conducted in collaboration with ABC2, Genentech and OSI Pharmaceuticals decided not to proceed to the second stage based upon a lower-than-expected objective response with single-agent Tarceva in this setting. Research on the potential to use Tarceva in the treatment of GBM will be pursued through ongoing investigator-sponsored trials.

Combination Targeted Therapies:  Genentech and OSI Pharmaceuticals announced at ASCO results from Phase I/II clinical studies examining the combination of Avastin and Tarceva in the treatment of metastatic renal cell carcinoma (kidney cancer) and relapsed non-small cell lung cancer (NSCLC). Other studies of this combination were presented, including metastatic breast cancer and head and neck cancer.

Genentech added to its development pipeline a randomized, multi-center Phase II study of the combination of Avastin and Tarceva in patients with first-line metastatic renal cell carcinoma, based on positive Phase II single-arm trial data.

Rituxan:  Also at ASCO, Genentech, Biogen Idec Inc. and Roche announced positive data from a large, randomized Phase III cooperative group trial (E1496) evaluating Rituxan as maintenance therapy for newly diagnosed patients with indolent non-Hodgkin's lymphoma (NHL) following initial (induction) treatment with chemotherapy. The study authors concluded that there was a significant improvement in progression-free survival (PFS), the primary endpoint of the study. Also presented were data from the MabThera International Trial (MinT) study of R-CHOP (Rituxan, cyclophosphamide, doxorubicin, vincristine and prednisone) versus CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) in younger patients with newly diagnosed, aggressive NHL.

Earlier in the quarter, Roche announced the initial results of the European Organization for Research and Treatment of Cancer (EORTC) 20981 trial of Rituxan in patients with relapsed indolent NHL. The trial evaluated patients treated with Rituxan and CHOP or CHOP alone followed by Rituxan maintenance therapy for two years and was stopped early due to efficacy when initial results showed Rituxan to be the best therapeutic option in both arms of the trial.

- 5 -

Herceptin:  In June, Roche announced that the European Commission approved the use of Herceptin in combination with Taxotere® (docetaxel) in the European Union as a first-line therapy in HER2-positive metastatic breast cancer patients who have not yet received chemotherapy.

As presented at ASCO, a Phase II investigator-sponsored study of Herceptin plus anthracycline chemotherapy versus anthracycline chemotherapy alone in the neoadjuvant setting was stopped early when initial results demonstrated a significant increase in pathological complete response in patients with operable breast cancer. While there were no observed cases of congestive heart failure (CHF) in this small study, there has been an increased incidence of CHF reported with the use of Herceptin in patients previously treated with anthracyclines.

Omnitarg&trade  (pertuzumab):  In the Phase II open-label trial of Omnitarg, evidence was observed of anti-tumor activity, including objective responses and durable stable disease in patients with advanced, relapsed/refractory ovarian cancer. While there was evidence of clinical benefit in the trial, the objective response rate was not adequate for an accelerated approval or pursuit of a Phase III trial for single-agent therapy in ovarian cancer at this time. Moving forward, Omnitarg will be evaluated in combination with chemotherapy in a Phase II trial in ovarian cancer.

Immunology and Specialty Biotherapeutics

Xolair:  Genentech, with Novartis Pharma AG and Tanox, Inc., enrolled the first patient in the Phase II Xolair peanut allergy study of 150 patients, also known as TOPS.

Novartis Pharma AG submitted its application for the European approval of Xolair to the European Agency for the Evaluation of Medicinal Products (EMEA) Committee for Medicinal Products for Human Use (CHMP).

Rituxan:  Genentech, Biogen Idec and Roche announced in June that The New England Journal of Medicine published the results of a Phase IIa study showing that two doses of Rituxan, administered two weeks apart, improved symptoms in patients with moderate-to-severe rheumatoid arthritis (RA) for up to 48 weeks when combined with methotrexate (MTX), compared to MTX alone.

In June, Genentech enrolled the first patient in the OLYMPUS study, a Phase II/III study of Rituxan in patients with primary progressive multiple sclerosis (PPMS).

RAPTIVA:  Serono S.A. announced that CHMP made a unanimous recommendation for approval of RAPTIVA in the European Union.

- 6 -

BR3-Fc:  A new molecular entity for rheumatoid arthritis, a BR3 fusion protein, which resulted from a collaboration with Biogen Idec, has been entered into the development pipeline.

Nutropin Depot:  In June, Genentech and Alkermes Inc. announced their decision to discontinue commercialization of Nutropin Depot. The decision was based on the significant resources required by both companies to continue manufacturing and commercializing the product.

CORPORATE EVENTS

The Genentech board of directors approved a two-for-one split of common stock in the form of a stock dividend. The stock split's record date was April 28, 2004, and additional shares were distributed beginning May 12, 2004. Genentech also announced the election of William M. Burns, head of Pharmaceuticals of the Roche Group, and Erich Hunziker, Ph.D., chief financial officer of the Roche Group, to the board of directors. Franz B. Humer, chairman and chief executive officer of the Roche Group, resigned from the board.

The Genentech Foundation for Biomedical Sciences, an independent foundation, awarded 23 grants totaling $1,061,090 to San Francisco Bay Area educational institutions that support biomedical research and education for local students.

Genentech announced the following senior officer promotions and appointments:  Vince Anicetti was promoted to vice president, Product Portfolio Management; Martin Babler was promoted to vice president, Immunology Sales and Marketing; Charlie Johnson was promoted to vice president, Clinical Biotherapeutics; and Karen McCormick was hired as vice president, Specialty Therapeutic Sales & Marketing.

The statements made in this press release relating to the potential launch of Tarceva and 2004 non-GAAP EPS are forward-looking and actual results could differ materially. Among other things, the potential launch of Tarceva could be impacted by a number of factors, including manufacturing issues, discussions with the FDA, the need for additional clinical studies, FDA actions or delays, or the failure to receive FDA approval; and 2004 non-GAAP EPS could be impacted by all of the foregoing and by competition, pricing, new product approvals and launches, government reimbursement rates, the ability to supply product, product withdrawals, achieving sales revenue consistent with internal forecasts, unanticipated expenses such as litigation or legal settlement expenses or equity securities writedowns, costs of sales, R&D expenses, fluctuations in contract revenues and royalties, and fluctuations in tax and interest rates. Genentech disclaims any obligation and does not undertake to upda te or revise the forward-looking statements discussed in this press release.

# # #

- 7 -

GENENTECH, INC. CONDENSED CONSOLIDATED STATEMENTS OF INCOME (in thousands, except per share amounts) (unaudited)
		Three Months Ended June 30,
		2004							2003
		GAAP(1)		Differences			Non-GAAP(2)		GAAP(1)		Differences			Non-GAAP(2)
Revenues:
Product sales		$	913,366				$	913,366	$	644,324				$	644,324
Royalties			151,860					151,860		122,786					122,786
Contract revenue			62,852					62,852		32,602					32,602
Total operating revenues			1,128,078					1,128,078		799,712					799,712
Costs and expenses:
Cost of sales			186,683					186,683		123,407					123,407
Research and development			212,886					212,886		180,203					180,203
Marketing, general and administrative			276,654					276,654		184,258					184,258
Collaboration profit sharing			145,221					145,221		107,307					107,307
Recurring charges related to redemption			38,209	$	(38,209)	(3)		-		38,586	$	(38,586)	(3)		-
Special charges:  litigation-related			13,458		(13,458)	(4)		-		13,363		(13,363)	(4)		-
Total costs and expenses			873,111		(51,667)			821,444		647,124		(51,949)			595,175
Operating margin			254,967		51,667			306,634		152,588		51,949			204,537
Other income, net(5)			15,444		-			15,444		40,870		-			40,870
Income before taxes			270,411		51,667			322,078		193,458		51,949			245,407
Income tax provision			99,640		20,666			120,306		61,113		20,779			81,892
Net income		$	170,771	$	31,001		$	201,772	$	132,345	$	31,170		$	163,515
Earnings per share:(6)
	Basic	$	0.16	$	0.03		$	0.19	$	0.13	$	0.03		$	0.16
	Diluted	$	0.16	$	0.03		$	0.19	$	0.13	$	0.03		$	0.16
Weighted average shares used to compute    earnings per share: (6)
Basic			1,060,619					1,060,619		1,025,818					1,025,818
Diluted			1,087,087					1,087,087		1,045,829					1,045,829

___________________

(1)	Reflects operating results in accordance with U.S. generally accepted accounting principles (or GAAP).
(2)	Non-GAAP amounts exclude litigation-related special charges and recurring charges related to the 1999 redemption of Genentech's Special Common Stock, net of related taxes.
(3)	Represents the amortization of other intangible assets related to the 1999 redemption of Genentech's Special Common Stock.
(4)	Represents accrued interest and bond costs related to the City of Hope trial judgment.
(5)	"Other income, net" includes realized gains and losses from the sale of certain biotechnology equity securities and write-downs for other-than-temporary declines in the fair value of certain biotechnology debt and equity securities. In addition, "other income, net" includes interest income and interest expense. For further detail, refer to our web site at www.gene.com.
(6)	All share and per share amounts reflect the May 2004 two-for-one stock split of our Common Stock. 2004 Reconciliation of GAAP and Non-GAAP EPS Our 2004 GAAP EPS is not estimable at this time. The 2004 GAAP EPS would include recurring charges related to the 1999 redemption of our stock by Roche, which are estimated to be approximately $145 million on a pretax basis in 2004. In addition, the 2004 GAAP EPS would include litigation-related special charges for accrued interest and associated bond costs on the City of Hope judgment, which are estimated to be approximately $54 million on a pretax basis in 2004. The 2004 non-GAAP EPS estimate does not include the redemption related recurring charges and the litigation-related special charges or any other potential special charges related to existing or future litigation or its resolution, or changes in accounting principles, all of which may be significant.

- 8 -

GENENTECH, INC. CONDENSED CONSOLIDATED STATEMENTS OF INCOME (in thousands, except per share amounts) (unaudited)
		Six Months Ended June 30,
		2004							2003
		GAAP(1)		Differences			Non-GAAP(2)		GAAP(1)		Differences			Non-GAAP(2)
Revenues:
Product sales		$	1,677,066				$	1,677,066	$	1,242,806				$	1,242,806
Royalties			305,957					305,957		236,061					236,061
Contract revenue			120,190					120,190		70,517					70,517
Total operating revenues			2,103,213					2,103,213		1,549,384					1,549,384
Costs and expenses:
Cost of sales			301,163					301,163		238,249					238,249
Research and development			403,231					403,231		337,636					337,636
Marketing, general and administrative			523,968					523,968		321,480					321,480
Collaboration profit sharing			271,652					271,652		203,854					203,854
Recurring charges related to redemption			76,418	$	(76,418)	(3)		-		77,172	$	(77,172)	(3)		-
Special charges:  litigation-related			26,857		(26,857)	(4)		-		26,608		(26,608)	(4)		-
Total costs and expenses			1,603,289		(103,275)			1,500,014		1,204,999		(103,780)			1,101,219
Operating margin			499,924		103,275			603,199		344,385		130,780			448,165
Other income, net(5)			37,765		-			37,765		56,573		-			56,573
Income before taxes			537,689		103,275			640,964		400,958		130,780			504,738
Income tax provision			190,331		41,310			231,641		117,143		41,511			158,654
Net income		$	347,358	$	61,965		$	409,323	$	283,815	$	62,269		$	346,084
Earnings per share: (6)
	Basic	$	0.33	$	0.06		$	0.39	$	0.28	$	0.06		$	0.34
	Diluted	$	0.32	$	0.06		$	0.38	$	0.27	$	0.06		$	0.33
Weighted average shares used to compute    earnings per share: (6)
Basic			1,057,955					1,057,955		1,024,796					1,024,796
Diluted			1,084,618					1,084,618		1,040,204					1,040,204

___________________

(1)	Reflects operating results in accordance with U.S. generally accepted accounting principles (or GAAP).
(2)	Non-GAAP amounts exclude litigation-related special charges and recurring charges related to the 1999 redemption of Genentech's Special Common Stock, net of related taxes.
(3)	Represents the amortization of other intangible assets related to the 1999 redemption of Genentech's Special Common Stock.
(4)	Represents accrued interest and bond costs related to the City of Hope trial judgment.
(5)	"Other income, net" includes realized gains and losses from the sale of certain biotechnology equity securities and write-downs for other-than-temporary declines in the fair value of certain biotechnology debt and equity securities. In addition, "other income, net" includes interest income and interest expense. For further detail, refer to our web site at www.gene.com.
(6)	All share and per share amounts reflect the May 2004 two-for-one stock split of our Common Stock.

- 9 -

GENENTECH, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (in thousands) (unaudited)
	June 30,
	2004			2003(6)
Selected balance sheet data:
Cash, cash equivalents and short-term investments	$	1,619,134		$	1,215,813
Accounts receivable - product sales, net		464,032			270,993
Accounts receivable - royalties, net		189,513			140,693
Accounts receivable - other, net		88,901			267,770
Inventories		527,649			422,414
Long-term marketable debt and equity securities		1,414,663			785,877
Property, plant and equipment, net		1,740,423	(4)		1,146,875
Goodwill		1,315,019			1,315,019
Other intangible assets		710,644			865,719
Other long-term assets		817,906			793,345
Total assets		9,055,039			7,459,115
Total current liabilities		836,876			598,721
Total liabilities		2,170,005	(5)		1,606,182
Total stockholders' equity		6,885,034			5,852,933
Year-to-date:
Capital expenditures	$	196,633		$	140,145
Total GAAP(1) depreciation and amortization expense		178,520			144,871
Less:  redemption related amortization expense(3)		(76,418)			(77,172)
Non-GAAP(2) depreciation and amortization expense	$	102,102		$	67,699

___________________

(1)	In accordance with U.S. generally accepted accounting principles (or GAAP).
(2)	Non-GAAP amounts exclude amortization of other intangible assets related to the 1999 redemption of Genentech's Special Common Stock.
(3)	Represents the amortization of other intangible assets related to the 1999 redemption of Genentech's Special Common Stock.
(4)	Includes $338 million of assets related to the consolidation of a variable interest entity pursuant to Financial Accounting Standards Board Interpretation No. 46 (or FIN 46) on July 1, 2003.
(5)	Includes $412 million of debt related to the consolidation of a variable interest entity pursuant to FIN 46.
(6)	Certain reclassifications of prior period amounts have been made to conform with the current year presentation.

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