Prudential Jennison Small Company Fund, Inc.
Gateway Center Three
100 Mulberry Street, 9th Floor
Newark, N.J.  07102-4077



                                                       December 9, 2010



Securities and Exchange Commission
450 Fifth Street, NW
Washington, DC  20549

	Re:	Rule 24f-2 Notice for Prudential Jennison Small Company Fund, Inc.
		File Nos. 811-3084 and 02-68723

On behalf of the Prudential Jennison Small Company Fund, Inc., enclosed for
filing under the Investment Company Act of 1940, is one copy of the Rule
24f-2 Notice. This document has been filed using the EDGAR system.  Should you
have any questions, please contact me at (973) 367-7503.

							Very truly yours,


							/s/ Grace C. Torres

							Grace C. Torres
							Treasurer