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Stock Based Option Compensation and Restricted Stock Compensation (Tables)
9 Months Ended
Sep. 30, 2018
Stock Options [Member]  
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]  
Summarization of stock-based compensation
The following table summarizes stock-based option compensation for the three and nine months ended September 30, 2018 and 2017:
 
 
 
Three months ended
 
 
Nine months ended
 
 
 
September 30,
 
 
September 30,
 
 
 
2018
 
 
2017
 
 
2018
 
 
2017
 
Research and development
 
$
1,012,000
 
 
$
394,000
 
 
$
2,756,000
 
 
$
1,118,000
 
General and administrative
 
 
1,487,000
 
 
 
398,000
 
 
 
4,316,000
 
 
 
2,409,000
 
Stock-based option compensation expense included in operating expense
 
$
2,499,000
 
 
$
792,000
 
 
$
7,072,000
 
 
$
3,527,000
 
Restricted Stock [Member]  
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]  
Summarization of stock-based compensation
The following table summarizes restricted common stock compensation expense for the three and nine months ended September 30, 2018 and 2017:
 
 
 
Three months ended
 
 
Nine months ended
 
 
 
September 30,
 
 
September 30,
 
 
 
2018
 
 
2017
 
 
2018
 
 
2017
 
General and administrative
 
$
172,000
 
 
$
293,000
 
 
$
516,000
 
 
$
979,000
 
Restricted stock compensation expense included in operating expense
 
$
172,000
 
 
$
293,000
 
 
$
516,000
 
 
$
979,000