Exhibit 107

Calculation of Filing Fees Tables

424(b)(2)

(Form Type)

Amgen Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

	Security Type		Security Class Title	Fee Calculation or Carry Forward Rule			Amount Registered		Proposed Maximum Offering Price Per Unit			Maximum Aggregate Offering Price		Fee Rate		Amount of Registration Fee		Carry Forward Form Type		Carry Forward File Number		Carry Forward Initial effective date		Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward
Newly Registered Securities
Fees to Be Paid		Debt	5.250% Senior Notes due 2025		457	(r)	$	2,000,000,000		99.934	%	$	1,998,680,000		0.0001102	$	220,254.54
Fees to Be Paid		Debt	5.507% Senior Notes due 2026		457	(r)	$	1,500,000,000		100.000	%	$	1,500,000,000		0.0001102	$	165,300.00
Fees to Be Paid		Debt	5.150% Senior Notes due 2028		457	(r)	$	3,750,000,000		99.826	%	$	3,743,475,000		0.0001102	$	412,530.95
Fees to Be Paid		Debt	5.250% Senior Notes due 2030		457	(r)	$	2,750,000,000		99.769	%	$	2,743,647,500		0.0001102	$	302,349.95
Fees to Be Paid		Debt	5.250% Senior Notes due 2033		457	(r)	$	4,250,000,000		99.685	%	$	4,236,612,500		0.0001102	$	466,874.70
Fees to Be Paid		Debt	5.600% Senior Notes due 2043		457	(r)	$	2,750,000,000		99.441	%	$	2,734,627,500		0.0001102	$	301,355.95
Fees to Be Paid		Debt	5.650% Senior Notes due 2053		457	(r)	$	4,250,000,000		99.856	%	$	4,243,880,000		0.0001102	$	467,675.58
Fees to Be Paid		Debt	5.750% Senior Notes due 2063		457	(r)	$	2,750,000,000		99.072	%	$	2,724,480,000		0.0001102	$	300,237.70
Fees Previously Paid		—	—		—			—		—			—		—		—		—		—		—		—
Carry Forward Securities
Carry Forward Securities		X	X		X			X					X						X		X		X		X
		Total Offering Amounts										$	23,925,402,500				$2,636,579.36
		Total Fees Previously Paid											—				X
		Total Fee Offsets											—				X
		Net Fee Due															$2,636,579.36