Exhibit 25.1

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM T-1

STATEMENT OF ELIGIBILITY
UNDER THE TRUST INDENTURE ACT OF 1939 OF A
CORPORATION DESIGNATED TO ACT AS TRUSTEE

CHECK IF AN APPLICATION TO DETERMINE ELIGIBILITY OF A TRUSTEE
PURSUANT TO SECTION 305(b)(2) o

LASALLE BANK NATIONAL ASSOCIATION

(Exact name of trustee as specified in its charter)

36-0884183
(I.R.S. Employer
Identification No.)

135 South LaSalle Street, Chicago, Illinois 60603
(Address of principal executive offices) (Zip Code)

Willie J. Miller, Jr.
Group Senior Vice President
Chief Legal Officer and Secretary
Telephone: (312) 904-2018
135 South LaSalle Street, Suite 925
Chicago, Illinois 60603
(Name, address and telephone number of agent for service)

Amgen Inc.
(Exact name of obligor as specified in its charter)

Delaware	95-3540776
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification No.)

One Amgen Center Drive
Thousand Oaks, California	91320-1799
(Address of principal executive offices)	(Zip Code)

Zero Coupon Convertible Notes due 2032
(Title of the indenture securities)

ITEM 1. GENERAL INFORMATION

Furnish the following information as to the trustee:

(a)   Name and address of each examining or supervising authority to which it is subject.

1.	Comptroller of the Currency, Washington D.C.
2.	Federal Deposit Insurance Corporation, Washington, D.C.
3.	The Board of Governors of the Federal Reserve Systems, Washington, D.C.

(b)   Whether it is authorized to exercise corporate trust powers.

Yes.

ITEM 2. AFFILIATIONS WITH THE OBLIGOR AND GUARANTORS.

If the obligor or any guarantor is an affiliate of the trustee, describe each such affiliation.

None.

ITEMS 3 THROUGH 15, INCLUSIVE, ARE NOT APPLICABLE BY VIRTUE OF T-1 GENERAL INSTRUCTION B.

[REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK]

ITEM 16. LIST OF EXHIBITS.

List below all exhibits filed as part of this statement of eligibility and qualification.

1.	A copy of the Articles of Association of LaSalle Bank National Association now in effect. (incorporated herein by reference to Exhibit 1 filed with Form T-1 filed with the Current Report on Form 8-K, dated June 29, 2000, in File No. 333-61691).
2.	A copy of the certificate of authority to commence business (incorporated herein by reference to Exhibit 2 filed with Form T-1 filed with the Current Report on Form 8-K, dated June 29, 2000, in File No. 333-61691).
3.	A copy of the authorization to exercise corporate trust powers (incorporated herein by reference to Exhibit 3 filed with Form T-1 filed with the Current Report on Form 8-K, dated June 29, 2000, in File No. 333-61691).
4.	A copy of the existing By-Laws of LaSalle Bank National Association (incorporated herein by reference to Exhibit 4 filed with Form T-1 filed with the Current Report on Form 8-K, dated June 29, 2000, in File No. 333-61691).
5.	Not applicable.
6.	The consent of the trustee required by Section 321(b) of the Trust Indenture Act of 1939 (incorporated herein by reference to Exhibit 6 filed with Form T-1 filed with the Current Report on Form 8-K, dated June 29, 2000, in File No. 333-61691).
7.	A copy of the latest report of condition of the trustee published pursuant to law or the requirements of its supervising or examining authority.
8.	Not applicable.
9.	Not applicable.

SIGNATURE

Pursuant to the requirements of the Trust Indenture Act of 1939, the trustee, LaSalle Bank National Association, a corporation organized and existing under the laws of the United States of America, has duly caused this statement of eligibility to be signed on its behalf by the undersigned, thereunto duly authorized, all in the City of Chicago, State of Illinois, on the 18th day of March, 2005.

LASALLE BANK NATIONAL ASSOCIATION
By:	/s/ John W. Porter
	John W. Porter Vice President

LaSalle Bank N.A.	Call Date: 12/31/2004	ST-BK: 17-1520	FFIEC		031
135 South LaSalle Street			Page		RC-1
Chicago, IL 60603	Vendor ID: D	CERT: 15407		11

Transit Number: 71000505

Consolidated Report of Condition for Insured Commercial and
State-Chartered Savings Banks for December 31, 2004

All schedules are to be reported in thousands of dollars. Unless otherwise indicated,
report the amount outstanding as of the last business day of the quarter.

Schedule RC — Balance Sheet

						Dollar Amounts in Thousands
ASSETS
1.	Cash and balances due from depository institutions (from Schedule RC-A):			RCFD
	a. Noninterest-bearing balances and currency and coin (1)				0081		1,654,813	1.a
	b. Interest-bearing balances (2)				0071		21,671	1.b
2.	Securities:
	a. Held-to-maturity securities (from Schedule RC-B, column A)				1754		98,557	2.a
	b. Available-for-sale securities (from Schedule RC-B, column D)				1773		21,275,790	2.b
3.	Federal funds sold and securities purchased under agreements to resell
	a. Federal funds sold in domestic offices				B987		534,180	3.a
	b. Securities purchased under agreements to resell (3)				B989		1,375,515	3.b
4.	Loans and lease financing receivables (from schedule RC-C)
	a. Loans and leases held for sale				5369		461,153	4.a
	b. Loans and leases, net of unearned income	B528	35,922,737
	c. LESS: Allowance for loan and lease losses	3123	663,290					4.c
	d. Loans and leases, net of unearned income, allowance, and reserve (item 4.a minus 4.b				B529		35,259,447	4.d
	and 4.c)
5.	Trading assets (from Schedule RC-D)				3545		455,947	5.
6.	Premises and fixed assets (including capitalized leases)				2145		282,308	6.
7.	Other real estate owned (from Schedule RC-M)				2150		11,312	7.
8.	Investments in unconsolidated subsidiaries and associated companies (from Schedule RC-M)				2130		0	8.
9.	Customers’ liability to this bank on acceptances outstanding				2155		19,975	9.
10.	Intangible assets (from Schedule RC-M)
	a. Goodwill				3163		181,613	10.a
	b. Other Intangible assets				0426		0	10.b
11.	Other assets (from Schedule RC-F)				2160		2,102,546	11.
12.	Total assets (sum of items 1 through 11)				2170		63,734,827	12.

(1)	Includes cash items in process of collection and unposted debits.
(2)	Includes time certificates of deposit not held for trading.
(3)	Includes all securities resale agreements in domestic and foreign offices, regardless of maturity.

LaSalle Bank N.A.	Call Date: 12/31/2004	ST-BK: 17-1520	FFIEC		031
135 South LaSalle Street			Page		RC-2
Chicago, IL 60603	Vendor ID: D	CERT: 15407		12

Transit Number: 71000505

Schedule RC — Continued

								Dollar Amounts in Thousands
LIABILITIES
13.	Deposits:
	a.	In domestic offices (sum of totals of				RCON
		columns A and C from Schedule RC-E, part I)					2200		30,303,455	13.a
				RCON
		(1)	Noninterest-bearing (1)	6631	7,265,226					13.a.1
		(2)	Interest-bearing	6636	23,038,229					13.a.2
						RCFN
	b.	In foreign offices, Edge and Agreement subsidiaries, and IBFs (from Schedule RC-E,
		part II)					2200		7,437,278	13.b
				RCFN
		(1)	Noninterest-bearing	6631	0					13.b.1
		(2)	Interest-bearing	6636	7,437,278					13.b.2
						RCON
14.	Federal funds purchased and securities sold under agreements to repurchase:
	a.	Federal funds purchased in domestic offices (2)					B993		2,192,955	14.a
						RCFD
	b.	Securities sold under agreements to repurchase (3)					B995		7,102,085	14.b
15.	Trading liabilities (from Schedule RC-D)						3548		138,932	15
16.	Other borrowed money (includes mortgage indebtedness and obligations
	under capitalized leases): From schedule RC-M						3190		8,560,613	16
17.	Not applicable.
18.	Bank’s liability on acceptances executed and outstanding						2920		19,975	18.
19.	Subordinated notes and debentures (4)						3200		540,000	19.
20.	Other liabilities (from Schedule RC-G)						2930		1,955,957	20.
21.	Total liabilities (sum of items 13 through 20)						2948		58,251,250	21.
22.	Minority Interest in consolidated subsidiaries						3000		66,678	22.
EQUITY CAPITAL						RCFD
23.	Perpetual preferred stock and related surplus						3838		500,000	23.
24.	Common stock						3230		41,234	24.
25.	Surplus (exclude all surplus related to preferred stock)						3839		2,010,375	25.
26.	a.	Retained Earnings					3632		2,558,905	26.a
	b.	Accumulated Other Comprehensive income.(5)					B530		306,385	26.b
27.	Other Equity capital components (6)						3284		0	27.
28.	Total equity capital (sum of items 23 through 27)						3210		5,416,899	28.
29.	Total liabilities, minority interest, and equity capital (sum of items 21, 22, and 28)						3300		63,734,827	29.

Memorandum

To be reported only with the March Report of Condition.

1.	Indicate in the box at the right the number of the statement below that best describes
	the most comprehensive level of auditing work performed for the bank by independent	RCFD	Number
	external auditors as of any date during 2001	6724	N/A	M.1

1 =	Independent audit of the bank conducted in accordance with generally accepted auditing standards by a certified public accounting firm which submits a report on the bank
2 =	Independent audit of the bank’s parent holding company conducted in accordance with generally accepted auditing standards by a certified public accounting firm which submits a report on the consolidated holding company (but not on the bank separately)
3 =	Attestation on bank managements assertion on the effectiveness of the bank’s internal control over financial reporting by a certified public accounting firm
4 =	Directors’ examination of the bank conducted in accordance with generally accepted auditing standards by a certified accounting firm (may be required by state chartering authority)

5 =	Directors’ examination of the bank performed by other external auditors (may be required by state chartering authority)
6 =	Review of the bank’s financial statements by external auditors
7 =	Compilation of the bank’s financial statements by external auditors
8 =	Other audit procedures (excluding tax preparation work)
9 =	No external audit work

(1)	Includes total demand deposits and noninterest-bearing time and savings deposits.
(2)	Report overnight Federal Home Loan Bank advances in Schedule RC, item 16 “other borrowed money.”
(3)	Includes all securities repurchased agreements in domestic and foreign offices, regardless of maturity.
(4)	Includes limited-life preferred stock and related surplus.
(5)	Includes net unrealized holding gains(losses) on available for sale securities, accumulated net gains (losses) on cash flow hedges, cumulative foreign currency translation adjustments, and minimum pension liability adjustments.
(6)	Includes treasury stock and unearned Employee Stock Ownership plan shares.