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Derivative instruments - Summary of Income and Expense Line Items (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales $ 7,447 $ 6,105
Other (expense) income, net (235) 2,064
Interest expense, net (824) (543)
Interest rate swap agreements    
Derivative Instruments, Gain (Loss) [Line Items]    
Gains (losses) on fair value hedging relationships, Hedged items 49 (88)
Gains (losses) on fair value hedging relationships, Derivatives designated as hedging instruments (28) 114
Reclassification out of Accumulated Other Comprehensive Income | Cash flow hedges | Cross-currency swap contracts    
Derivative Instruments, Gain (Loss) [Line Items]    
Other (expense) income, net (31) (22)
Product sales    
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales 7,118 5,846
Product sales | Reclassification out of Accumulated Other Comprehensive Income | Cash flow hedges | Foreign currency forward contracts    
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales $ 51 $ 52