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Acquisitions - Acquisition of Horizon Therapeutics plc (Details) - USD ($)
$ / shares in Units, shares in Millions, $ in Millions
3 Months Ended
Oct. 06, 2023
Mar. 31, 2024
Dec. 31, 2023
Business Acquisition [Line Items]      
Goodwill   $ 18,570 $ 18,629
Horizon Therapeutics      
Business Acquisition [Line Items]      
Acquisition price per share (in dollars per share) $ 116.50    
Consideration transferred $ 27,800    
Cash purchase price 26,700    
Consideration transferred for vested and outstanding awards 523    
Consideration transferred for replacement awards 180    
Liabilities incurred $ 382    
Replacement equity awards issued (in shares) 1.7    
Inventories $ 5,025 $ 5,000  
Business combination, turnover period of inventory acquired   27 months  
Deferred tax liability 2,492    
Deferred tax asset 834    
Goodwill 3,062    
Goodwill increase (decrease)   $ (49)  
Horizon Therapeutics | Developed-product-technology rights      
Business Acquisition [Line Items]      
Estimated fair value $ 20,700    
Weighted average period of amortization 10 years