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Collaborations - Kyowa Kirin (Details) - Kyowa Kirin Co. Ltd. - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Sep. 30, 2021
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Up-front payment $ 400      
Contingent future milestone payments   $ 850    
Research and development        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Cost recoveries   $ 93 $ 0 $ 0