Collaborations - AstraZeneca PLC (Details) - AstraZeneca PLC - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Research and development
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Development costs due to collaboration partner	$ 77	$ 74	$ 49
Selling, general and administrative
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cost recoveries	73	60	$ 39
Cost of sales
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Profit and loss share of expenses	$ 310	$ 119