Acquisitions and divestitures - Divestiture of Gensenta (Details) - USD ($) $ in Millions		12 Months Ended
Nov. 02, 2022	Dec. 31, 2022
Business Acquisition [Line Items]
Proceeds from divestiture of businesses	$ 130
Divested assets	$ 86
Foreign currency translation, loss on divestiture of a business		$ 615
Other general expense
Business Acquisition [Line Items]
Loss on divestiture		$ 567

Foreign currency translation, loss on divestiture of a business

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Amount classified as assets attributable to disposal group held for sale or disposed of.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of gain (loss) from sale and disposal of integrated set of activities and assets capable of being conducted and managed for purpose of providing return in form of dividend, lower cost, or other economic benefit to investor, owner, member and participant.

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The cash inflow associated with the amount received from the sale of a portion of the company's business, for example a segment, division, branch or other business, during the period.

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