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Acquisitions and divestitures - Summary of Total Consideration for ChemoCentryx Inc (Details) - USD ($)
$ in Millions
Dec. 31, 2023
Dec. 31, 2022
Oct. 20, 2022
Dec. 31, 2021
Business Acquisition [Line Items]        
Goodwill $ 18,629 $ 15,529   $ 14,890
ChemoCentryx, Inc.        
Business Acquisition [Line Items]        
Cash and cash equivalents     $ 86  
Marketable securities     235  
Inventories     41  
Goodwill     649  
Other liabilities, net     (83)  
Deferred tax liability, net     (502)  
Total assets acquired, net     3,925  
ChemoCentryx, Inc. | Developed-product-technology rights        
Business Acquisition [Line Items]        
Finite-lived intangible assets – developed-product-technology rights     $ 3,499